Risperidone combined with Valproic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Mental Status Changes Hospitalization 10/25/2005 Male 1/19/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 8/1/2003 37 Male 187 lb 1/20/2006
Primary
Secondary
Concomitant
Splenomegaly Other Serious 5/13/2005 62 Male 250 lb 2/10/2006 Physician United States
Primary
Concomitant
Psychotic Disorder Hospitalization 9 Male 3/8/2006 Physician United States
Primary
Secondary
Schizophrenia Hospitalization 55 Female 3/27/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/19/2005 8 Male 5/23/2006 Consumer Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 27 Female 6/20/2006 India
Primary
Concomitant
Tachycardia Death 6/1/2006 28 Male 176 lb 7/7/2006 Physician Ecuador
Primary
Concomitant
Hyperammonaemia Hospitalization 15 Male 7/21/2006 France
Primary
Concomitant
Granulocytopenia Required Intervention 12/7/2005 40 Female 220 lb 5/16/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 2/7/2006 45 Male 6/1/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/26/2005 36 Male 259 lb 1/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/8/2005 33 Male 153 lb 3/14/2006 Consumer United States
Primary
Concomitant
Status Epilepticus Hospitalization 15 Male 8/7/2006 France
Primary
Concomitant
Loss Of Consciousness Other Serious 8/9/2006 54 Female 170 lb 9/7/2006 Pharmacist United States
Primary
Concomitant
No Therapeutic Response Hospitalization 11 Female 1/3/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 22 Female 292 lb 10/10/2006 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/4/2005 Female 1/26/2007 Physician Canada
Primary
Concomitant
Overdose Other Serious 27 Male 3/9/2007 Japan
Primary
Secondary
Weight Increased Other Serious 33 Female 168 lb 3/14/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Mania Other Serious 11 Male 3/20/2007 France
Primary
Concomitant
Interacting
Mania Other Serious 11 Male 3/20/2007 France
Primary
Concomitant
Interacting
Urinary Incontinence Other Serious 53 Male 5/10/2007 Physician Canada
Primary
Concomitant
Tremor Hospitalization 11 Male 5/21/2007
Primary
Secondary
Tremor Hospitalization 11 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 30 Male 5/23/2007 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/16/2002 40 Female 5/26/2007 Physician Canada
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 27 Male 6/28/2007 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 191 lb Physician United States
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 27 Male 7/13/2007 Japan
Primary
Secondary
Concomitant
Respiration Abnormal Life Threatening 25 Female 7/17/2007 Physician India
Primary
Secondary
Shock Hospitalization 27 Male 7/30/2007
Primary
Secondary
Mania Other Serious 27 Male 7/30/2007 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 16 Male 7/30/2007 United Kingdom
Primary
Secondary
Shock Hospitalization 27 Male 8/10/2007 Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 25 Female 7/27/2007 India
Primary
Secondary
Oedema Peripheral Other Serious 16 Male 8/13/2007 United Kingdom
Primary
Secondary
Overdose Other Serious 1/1/2007 Male 9/21/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 25 Female 10/3/2007 Physician Netherlands
Primary
Secondary
Concomitant
Weight Increased Other Serious 25 Female 10/5/2007 Netherlands
Primary
Secondary
Concomitant
Weight Increased Other Serious 25 Female 10/24/2007 Netherlands
Primary
Secondary
Concomitant
Weight Increased Other Serious 25 Female 11/6/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Weight Increased Hospitalization 25 Female 11/20/2007
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Other Serious 1/1/2007 Male 154 lb 12/19/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 25 Female 12/18/2007 Netherlands
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 25 Male 3/17/2008 Physician Switzerland
Primary
Secondary
Concomitant
Sinus Tachycardia Life Threatening 10/2/2007 18 Male 4/29/2008 Sweden
Primary
Concomitant
Sinus Tachycardia Life Threatening 10/2/2007 18 Male 4/29/2008 Sweden
Primary
Concomitant
Sinus Tachycardia Life Threatening 10/2/2007 18 Male 4/30/2008 Sweden
Primary
Concomitant
Sensory Loss Other Serious 1/1/2005 Male 190 lb 4/30/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/29/2005 24 Female 5/1/2008 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/29/2005 24 Female 5/10/2008 Physician Australia
Primary
Concomitant
Sensory Loss Other Serious 1/1/2005 Male 190 lb 5/28/2008 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Death 35 6/9/2008 Other Health Professional United States
Primary
Secondary
Nocturnal Dyspnoea Hospitalization 59 Male 218 lb 6/24/2008 Other Health Professional Germany
Primary
Concomitant
Hyponatraemia Hospitalization 6/16/2008 58 Female 7/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Sleep Apnoea Syndrome Other Serious 59 Female 284 lb 8/6/2008
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 59 Male 218 lb 8/6/2008
Primary
Secondary
Concomitant
Neutropenia 55 Male 8/19/2008 United States
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 55 Male 8/25/2008 Physician United States
Primary
Secondary
Concomitant
Sensory Loss Other Serious 1/1/2005 Male 299 lb 9/12/2008 Consumer United States
Primary
Secondary
Concomitant
Medication Error Death 58 Male 12/23/2008 Physician United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 1/1/2007 43 Female 12/19/2008 Physician Canada
Primary
Concomitant
Medication Error Death 51 Female 12/29/2008 Physician United States
Primary
Secondary
Medication Error Death 58 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 51 Female 12/24/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 51 Female 1/6/2009 United States
Primary
Secondary
Multiple Drug Overdose Accidental Death 58 Male 1/7/2009 United States
Primary
Secondary
Medication Error Death 1/1/2007 58 Male 1/15/2009 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 51 Female 1/16/2009 United States
Primary
Secondary
Medication Error Death 58 Male 1/16/2009 United States
Primary
Secondary
Medication Error Death 58 Male 1/16/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 51 Female 1/15/2009 Physician United States
Primary
Secondary
Accidental Overdose Death 1/27/2009 Other Health Professional United States
Primary
Secondary
Poisoning Death 58 Male 1/21/2009 Physician United States
Primary
Secondary
Accidental Overdose Death 58 Male 1/21/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 51 Female 1/26/2009 Physician United States
Primary
Secondary
Death Death 1/1/2007 58 Male 2/3/2009 Pharmacist United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2007 51 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Unresponsive To Stimuli Death 10/4/2008 44 Female 225 lb 2/9/2009 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 51 Female 3/20/2009 Physician United States
Primary
Secondary
Status Epilepticus Death 15 Male 3/16/2009 Canada
Primary
Secondary
Concomitant
Medication Error Death 5/6/2009 Other Health Professional United States
Primary
Secondary
Medication Error Death 5/8/2009 Other Health Professional United States
Primary
Secondary
Pneumonia Other Serious 26 Female 5/13/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 45 Female 5/14/2009 Other Health Professional Brazil
Primary
Concomitant
Weight Increased Other Serious 5/1/2007 7 Male 6/10/2009 Physician Brazil
Primary
Secondary
Weight Increased 4/28/1999 Female 250 lb 7/24/2009 Physician United States
Primary
Concomitant
Sensory Loss Other Serious 1/1/2005 Male 299 lb 8/10/2009 Consumer United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 7/9/2009 51 Female 8/20/2009 United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 42 Female 8/28/2009
Primary
Secondary
Concomitant
Schizoaffective Disorder Other Serious 7/9/2009 51 Female 9/2/2009 United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 10/1/2008 40 Male 9/4/2009 Physician United Kingdom
Primary
Concomitant
Myocardial Ischaemia Other Serious 2/1/2009 65 Female 9/17/2009 Physician Denmark
Primary
Concomitant
Diabetic Ketoacidosis Other Serious Female 194 lb 9/23/2009 United States
Primary
Concomitant
Schizoaffective Disorder Other Serious 29 Male 10/2/2009
Primary
Secondary
Platelet Count Decreased Hospitalization 7/31/2009 52 Male 10/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Restlessness Hospitalization 66 Female 99 lb 10/12/2009 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 52 Male 10/21/2009 Physician Canada
Primary
Secondary
Psychotic Disorder Due To A General Medical Condition Hospitalization 30 Male 11/6/2009
Primary
Secondary
Psychotic Disorder Other Serious 16 Male 11/6/2009 Physician United States
Primary
Secondary
Hyponatraemia Other Serious 7/9/2009 51 Female 11/4/2009 United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 11/16/2009 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 1/1/2007 43 Female 11/30/2009 Physician Canada
Primary
Concomitant
Schizophrenia Other Serious 12/18/2009 Japan
Primary
Secondary
Tachycardia Other Serious 23 Female 12/30/2009 Other Health Professional United States
Primary
Secondary
Urinary Incontinence Other Serious 59 Female 157 lb 12/23/2009 Pharmacist United States
Primary
Secondary
Concomitant
Myoclonus Other Serious 66 Female 99 lb 1/14/2010 United States
Primary
Concomitant
Drug Ineffective 63 Female 1/25/2010 Physician United States
Primary
Secondary
Tremor Other Serious 10/1/2002 48 Male 1/29/2010
Primary
Secondary
Hyponatraemia Hospitalization 12/22/2009 64 Female 2/18/2010 Pharmacist United States
Primary
Concomitant
Hyperandrogenism Other Serious 6/1/2007 Female 154 lb 3/10/2010 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7 Female 75 lb 3/15/2010
Primary
Secondary
Myoclonus Hospitalization 38 Male 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 38 Male 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Restlessness Other Serious 12 Female 77 lb 4/16/2010 Other Health Professional India
Primary
Concomitant
Drug Ineffective Other Serious Female 6/24/2010 Physician United States
Primary
Secondary
Bipolar Disorder Other Serious 14 Female 6/29/2010 Other Health Professional Turkey
Primary
Secondary
Weight Increased Other Serious 39 Female 123 lb 7/2/2010
Primary
Secondary
Speech Disorder Other Serious 1/1/2005 21 Male 7/6/2010 Physician Korea, Republic Of
Primary
Concomitant
Incoherent Other Serious 19 Female 7/9/2010 Physician United States
Primary
Secondary
Hyponatraemia Hospitalization 1/1/2008 Male 5/19/2010 United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 31 Female 9/10/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 9/10/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Memory Impairment Other Serious 1/1/2010 47 Male 10/1/2010 Consumer United States
Primary
Concomitant
Hepatitis Hospitalization 8/1/2010 47 Female 10/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Memory Impairment Other Serious 1/1/2010 47 Male 10/19/2010 Consumer United States
Primary
Concomitant
Pain Other Serious 9/13/2010 36 Male 11/1/2010 Physician Canada
Primary
Concomitant
Hallucination, Auditory Other Serious 43 Male 300 lb 11/29/2010 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 66 Female 11/17/2010 Physician United Kingdom
Primary
Concomitant
Rhinorrhoea Hospitalization 11/6/2010 12 Male 12/10/2010 Physician Peru
Primary
Concomitant
Increased Bronchial Secretion Hospitalization 12/1/2009 11 Male 12/10/2010 Physician Peru
Primary
Concomitant
Cardio-respiratory Arrest Death 10 Male 1/4/2011 Other Health Professional United States
Primary
Secondary
Death Death 21 Female 1/10/2011 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process Death 10 Male 1/10/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 21 Female 1/12/2011 Physician United States
Primary
Secondary
Intentional Drug Misuse Hospitalization 10 Male 1/12/2011 Physician United States
Primary
Secondary
Completed Suicide Death 21 Female 1/21/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 10 Male 1/21/2011 Physician United States
Primary
Secondary
Poisoning Hospitalization 53 Male 1/27/2011 Other Health Professional Netherlands
Primary
Concomitant
Cardio-respiratory Arrest Other Serious 10 Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 1/1/2009 10 Male 1/26/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 1/1/2009 10 Male 1/26/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2009 10 Male 1/26/2011 Physician United States
Primary
Secondary
Microcytic Anaemia Other Serious Male 2/11/2011 Physician United Kingdom
Primary
Secondary
Acute Lung Injury Hospitalization 11/16/2009 11 Male 2/14/2011 Physician Peru
Primary
Concomitant
Blood Pressure Systolic Decreased Hospitalization 69 Female 2/2/2011 United Kingdom
Primary
Concomitant
Blister Hospitalization 69 Female 2/2/2011 United Kingdom
Primary
Concomitant

Drug Data