Risperidone combined with Valproate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thinking Abnormal Hospitalization 12/1/2004 38 Female 280 lb 1/19/2006 Consumer United Kingdom
Primary
Concomitant
Quadriparesis Other Serious 1/1/2005 47 Female 1/25/2006 Turkey
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 11/17/2005 44 Male 2/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Catatonia Hospitalization 3/6/2006 Male 181 lb 3/17/2006 Physician India
Primary
Concomitant
Neutrophil Count Decreased Other Serious 8/9/2005 54 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Hypokinesia Hospitalization 3/6/2006 Male 181 lb 4/7/2006 Physician India
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/31/2006 Male 4/10/2006 Physician France
Primary
Secondary
Concomitant
Drug Toxicity Death 11/19/2004 31 Male 375 lb 3/15/2005 Physician United States
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 12/23/1999 42 Female 4/25/2006 Physician Australia
Primary
Concomitant
Pancreatitis Other Serious 32 Male 4/19/2006 Physician Spain
Primary
Concomitant
Hypotension Hospitalization 2/3/2005 49 Female 5/25/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 2/3/2005 49 Female 121 lb 5/25/2006 Physician United Kingdom
Primary
Concomitant
Granulocytopenia Required Intervention 1/3/2006 52 Female 3/13/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/3/2006 60 Male 3/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/25/2006 23 Female 167 lb 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/12/2005 47 Female 2/28/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/26/2005 36 Male 259 lb 1/17/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 9/19/2005 44 Female 1/19/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/23/2005 44 Male 4/25/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/27/2005 70 Female 228 lb 3/9/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/3/2005 47 Male 2/14/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/20/2005 37 Male 220 lb 1/31/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/19/2005 31 Male 1/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/10/2005 48 Male 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/31/2005 47 Female 92 lb 2/13/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 10/31/2005 48 Female 3/7/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/8/2005 59 Female 3/22/2006 United States
Primary
Concomitant
Pyrexia Life Threatening 4/13/2006 29 Male 218 lb 5/23/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/3/2006 26 Female 5/30/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 9/13/2005 48 Male 1/13/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/29/2005 53 Female 1/5/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/22/2006 46 Female 5/8/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/31/2005 27 Male 4/25/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 3/1/2006 60 Female 5/18/2006 Consumer United States
Primary
Concomitant
Hiv Infection Death 2/13/2006 Male 9/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization 8/24/2006 30 Female 9/12/2006 Other Health Professional Japan
Primary
Concomitant
Status Epilepticus Hospitalization Female 198 lb 9/14/2006 Physician United Kingdom
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 8/24/2006 30 Female 9/19/2006 Other Health Professional Japan
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 8/24/2006 30 Female 10/6/2006 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 36 Male 10/13/2006 France
Primary
Concomitant
Interacting
Psychomotor Retardation Hospitalization 5/24/2005 67 Male 10/25/2006 Consumer Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 36 Male 11/3/2006 France
Primary
Concomitant
Interacting
Pancytopenia Hospitalization 36 Male 11/3/2006 Consumer France
Primary
Interacting
Grand Mal Convulsion Other Serious 10/25/2006 36 Female 11/13/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 36 Male 11/13/2006 France
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 36 Male 11/13/2006 France
Primary
Concomitant
Interacting
Sudden Death Death 7/7/2006 35 Male 269 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
Mental Impairment Hospitalization 11/7/2006 57 12/19/2006 United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2005 63 Female 12/19/2006 Japan
Primary
Secondary
Concomitant
Sudden Death Death 2/13/2006 Male 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 12 Female 1/2/2007 Physician Japan
Primary
Concomitant
Encephalopathy Other Serious 11 Female 1/5/2007 France
Primary
Concomitant
Tremor Hospitalization 60 Female 5/15/2007 Physician Taiwan, Province Of China
Primary
Concomitant
Pyrexia Other Serious 1/26/2007 17 Male 5/18/2007 United Kingdom
Primary
Concomitant
Tremor Other Serious 60 Female 5/25/2007 Taiwan, Province Of China
Primary
Secondary
Concomitant
Vasculitis Hospitalization 7/7/2006 30 Male 6/1/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/20/2007 18 Female 155 lb 6/4/2007 United Kingdom
Primary
Concomitant
Torticollis Other Serious 11 Female 6/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/1999 31 Female 156 lb 4/2/2007 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 5/6/2007 17 Male 6/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Death 38 Male 7/13/2007 Other Health Professional Denmark
Primary
Concomitant
Vomiting Death 2/3/2006 24 Female 7/27/2007 Physician Japan
Primary
Concomitant
Vomiting Death 2/3/2006 24 Female 7/30/2007 Physician Japan
Primary
Concomitant
Vomiting Death 2/3/2006 24 Female 8/8/2007 Physician Japan
Primary
Concomitant
Oedema Peripheral Other Serious 16 Male 8/10/2007 France
Primary
Concomitant
Interacting
Suicide Attempt Hospitalization 25 Female 8/14/2007 Other Health Professional India
Primary
Secondary
Neuroleptic Malignant Syndrome Other Serious 37 Female 9/5/2007
Primary
Secondary
Neuroleptic Malignant Syndrome Other Serious 37 Female 9/13/2007 Turkey
Primary
Secondary
Neuroleptic Malignant Syndrome Hospitalization 37 Female 10/5/2007
Primary
Secondary
Neuroleptic Malignant Syndrome Other Serious 37 Female 10/10/2007 Turkey
Primary
Secondary
Somnolence Other Serious Female 11/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Death 38 Male 11/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/1/2007 33 Male 12/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Parkinsonism Hospitalization 1/22/2007 Female 1/9/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Urticaria Hospitalization 3/4/2007 31 Female 1/18/2008 Consumer Sweden
Primary
Concomitant
Pneumonia Hospitalization Male 12/7/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 9/18/2007 51 Male 12/7/2007 United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 12/9/2007 28 Male 2/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Tachycardia Other Serious 2/15/2008 36 Female 110 lb 3/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 12/9/2007 28 Male 3/6/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Tachycardia Hospitalization 36 Female 3/19/2008 Other Health Professional France
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 12/9/2007 28 Male 3/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Tooth Extraction Other Serious 2/1/2008 Female 160 lb 3/28/2008 Canada
Primary
Concomitant
Sinus Tachycardia Life Threatening 10/2/2007 18 Male 4/29/2008 Sweden
Primary
Concomitant
Sinus Tachycardia Life Threatening 10/2/2007 18 Male 4/29/2008 Sweden
Primary
Concomitant
Sinus Tachycardia Life Threatening 10/2/2007 18 Male 4/30/2008 Sweden
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/29/2005 24 Female 5/1/2008 Physician Australia
Primary
Concomitant
Overdose Hospitalization 4/1/2008 36 Female 4/30/2008 Physician South Africa
Primary
Concomitant
Tachycardia Hospitalization 5/6/2008 45 Female 143 lb 5/9/2008 Physician Germany
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/29/2005 24 Female 5/10/2008 Physician Australia
Primary
Concomitant
Unevaluable Event Hospitalization 3/12/2008 21 Male 6/13/2008 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 3/12/2008 21 Male 6/19/2008 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2008 Female 160 lb 6/19/2008 Canada
Primary
Concomitant
Unevaluable Event Other Serious 3/12/2008 21 Male 6/30/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 1/1/2008 Male 7/7/2008 Pharmacist Canada
Primary
Concomitant
Hyponatraemia Hospitalization 6/16/2008 58 Female 7/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 6/29/2008 64 Male 7/29/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 8/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Herpes Zoster 3/26/2008 Male 250 lb 9/12/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 9/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 17 Female 10/9/2008 Physician Japan
Primary
Concomitant
Uveitis Other Serious 11/1/2004 Female 10/31/2008 Physician United Kingdom
Primary
Concomitant
Dementia Other Serious 35 Male 11/5/2008 Pharmacist France
Primary
Concomitant
Vomiting Other Serious 10/23/2008 Male 11/5/2008 Canada
Primary
Concomitant
Tremor Hospitalization 11/3/2005 Female 1/12/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 28 Male 1/27/2009 Other Health Professional United States
Primary
Secondary
Hallucination Hospitalization 6/9/2007 67 Male 212 lb 1/29/2009 Other Health Professional Japan
Primary
Concomitant
Troponin Increased Other Serious 28 Male 2 lb 1/23/2009 Physician United States
Primary
Secondary
Vomiting Other Serious 7/7/2008 Male 2/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hallucination Hospitalization 6/9/2008 67 Male 212 lb 2/4/2009 Other Health Professional Japan
Primary
Concomitant
Tremor Other Serious 2/6/2009 Pharmacist Japan
Primary
Concomitant
White Blood Cell Disorder Other Serious 28 Male 2/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 28 Male 2/6/2009 France
Primary
Secondary
Periorbital Oedema Other Serious 43 Female 2/20/2009 Canada
Primary
Secondary
Concomitant
Liver Disorder Other Serious 12/1/2008 14 Male 154 lb 3/2/2009 Physician Mexico
Primary
Concomitant
Tremor 3/4/2009 Physician United States
Primary
Concomitant
Weight Increased Female 3/4/2009 Physician United States
Primary
Concomitant
Drug Interaction 3/4/2009 Physician United States
Primary
Interacting
Mood Altered Other Serious 27 Female 3/25/2009 Physician Japan
Primary
Concomitant
Pulmonary Oedema Hospitalization 28 Male 3/23/2009 United States
Primary
Concomitant
Tachypnoea Other Serious 28 Male 3/26/2009 France
Primary
Secondary
Pulmonary Oedema Other Serious 28 Male 3/27/2009 United Kingdom
Primary
Secondary
Spinal Compression Fracture Hospitalization 2/3/2009 Male 198 lb 4/8/2009 Physician Australia
Primary
Concomitant
Liver Disorder Other Serious 12/1/2008 14 Male 154 lb 5/25/2009 Physician Mexico
Primary
Concomitant
Salivary Hypersecretion Hospitalization 42 Female 6/25/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 19 Male 6/25/2009 Physician Korea, Republic Of
Primary
Secondary
Interacting
Neuroleptic Malignant Syndrome Other Serious 3/1/2009 17 Male 176 lb 6/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 17 Male 6/23/2009 United Kingdom
Primary
Concomitant
Screaming Hospitalization 22 Female 7/8/2009 Consumer Japan
Primary
Concomitant
Screaming Hospitalization 22 Female 7/14/2009 Consumer Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/23/2009 Male 7/24/2009 Pharmacist Australia
Primary
Concomitant
Overdose Other Serious 1/1/2009 81 Female 7/16/2009 Other Health Professional Australia
Primary
Concomitant
Hypertension Other Serious 3/27/2009 16 Male 7/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/9/2004 48 Male 278 lb 7/29/2009 United States
Primary
Concomitant
Hypertension Other Serious 3/31/2009 16 Male 7/23/2009 United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 16 Male 7/27/2009 United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 1/1/2009 16 Male 85 lb 8/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 1/1/2009 Male 7/31/2009 Consumer United Kingdom
Primary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 8/18/2009 Consumer Germany
Primary
Secondary
Concomitant
Burning Sensation Other Serious 7/9/2009 51 Female 227 lb 8/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 7/9/2009 51 Female 227 lb 8/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 7/9/2009 51 Female 227 lb 8/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 1/1/2009 16 Male 8/14/2009 United Kingdom
Primary
Secondary
Concomitant
Skin Burning Sensation 9/28/2008 Male 8/21/2009 United States
Primary
Concomitant
Burning Sensation Other Serious 7/9/2009 51 Female 227 lb 8/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombosis Other Serious 44 Female 8/20/2009 Germany
Primary
Concomitant
Hyponatraemia Other Serious 7/9/2009 51 Female 8/19/2009 United Kingdom
Primary
Concomitant
Hyponatraemia Other Serious 7/9/2009 51 Female 227 lb 8/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Burning Sensation Other Serious 7/9/2009 51 Female 227 lb 8/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Burning Sensation Other Serious 7/9/2009 51 Female 227 lb 9/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data