Risperdal combined with Valproic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Agranulocytosis Required Intervention 4/20/2005 51 Male 194 lb 6/27/2005 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2005 47 Female 178 lb 1/23/2006 Physician United States
Primary
Concomitant
Lethargy Other Serious 26 Female 5/25/2006 Consumer Canada
Primary
Secondary
Concomitant
Anticonvulsant Drug Level Below Therapeutic Other Serious 8/1/2005 Female 179 lb 5/1/2006 Pharmacist United States
Primary
Concomitant
Fall Other Serious 6/1/2006 Female 6/28/2006 Physician Canada
Primary
Concomitant
Interacting
Treatment Noncompliance Other Serious 6/1/2006 75 Female 8/3/2006 Physician Canada
Primary
Concomitant
Interacting
Injury Asphyxiation Death Male 10/25/2006 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2000 50 Male 333 lb 11/8/2006 Lawyer United States
Primary
Concomitant
Tonsillar Disorder Required Intervention 15 Male 11/1/2006 Physician Canada
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2000 50 Male 333 lb 11/13/2006 Lawyer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2000 50 Male 333 lb 11/16/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 11/17/2006 72 Female 1/4/2007 Other Health Professional Canada
Primary
Concomitant
Sedation Required Intervention 68 Male 8/17/2006 Physician United States
Primary
Secondary
Weight Increased Other Serious 33 Female 168 lb 4/6/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Mania Other Serious 11 Male 4/10/2007 France
Primary
Concomitant
Interacting
Mania Other Serious 11 Male 4/10/2007 France
Primary
Concomitant
Interacting
Somnolence Other Serious 2/2/2007 46 Female 4/11/2007 Physician Canada
Primary
Secondary
Concomitant
Mania Other Serious 4/12/2007 Physician United States
Primary
Interacting
Mania Other Serious 4/12/2007 Physician United States
Primary
Interacting
Overdose Other Serious 27 Male 4/12/2007 Japan
Primary
Secondary
Vomiting Other Serious 1/1/2007 Female 143 lb 7/11/2007 Consumer United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 1/10/2003 11 Male 9/17/2007 Other Health Professional United States
Primary
Concomitant
Tardive Dyskinesia Hospitalization 10/16/2002 11 Male 11/2/2007 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Life Threatening 10/26/2007 5 Male 55 lb 11/5/2007 Pharmacist United States
Primary
Secondary
Tardive Dyskinesia Hospitalization 10/16/2002 11 Male 1/29/2008 Other Health Professional United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 43 Female 4/3/2008 Consumer Canada
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 43 Female 4/7/2008 Consumer Canada
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 4/11/2008 Female 176 lb 4/16/2008 Physician Germany
Primary
Secondary
Suicide Attempt Other Serious 4/11/2008 Female 176 lb 5/5/2008 Physician Germany
Primary
Secondary
Electrocardiogram Qt Prolonged Other Serious 43 Female 5/26/2008 Consumer Canada
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/26/2007 5 Male 55 lb 6/2/2008 Other Health Professional United States
Primary
Secondary
Sleep Apnoea Syndrome Other Serious 1/1/2004 37 Male 370 lb 7/10/2008 United States
Primary
Concomitant
Pneumonia Aspiration Other Serious 64 Female 8/4/2008 Physician Japan
Primary
Secondary
Ventricular Tachycardia Life Threatening 6/26/2008 Female 276 lb 8/12/2008 Physician Netherlands
Primary
Concomitant
Wrong Technique In Drug Usage Process 7/9/2008 29 Male 8/15/2008 United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization Female 115 lb 9/2/2008 Physician Japan
Primary
Secondary
Concomitant
Sedation Hospitalization 10/23/2007 Female 115 lb 9/5/2008 Physician Japan
Primary
Secondary
Concomitant
Blood Prolactin Increased 28 Female 9/24/2008 Pharmacist United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 11/1/2007 Female 115 lb 10/13/2008 Physician Japan
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 10/8/2002 10 Male 11/19/2008 United States
Primary
Concomitant
Pulmonary Embolism Death 3/4/2008 70 Female 11/19/2008 Physician Germany
Primary
Secondary
Concomitant
Pleurothotonus Hospitalization 2/12/2008 53 Female 12/23/2008 Physician Germany
Primary
Secondary
Electrocardiogram Qt Prolonged Other Serious 43 Female 1/16/2009 Physician Canada
Primary
Concomitant
Interacting
Schizoaffective Disorder Hospitalization 1/18/2001 38 Female 165 lb 1/20/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 1/20/2009 40 Female 2/11/2009 Physician Mexico
Primary
Concomitant
Therapeutic Response Unexpected 1/20/2009 40 Female 2/12/2009 Physician Mexico
Primary
Concomitant
Urinary Incontinence Life Threatening 9/15/2008 70 Male 2/23/2009 Pharmacist Switzerland
Primary
Concomitant
Interacting
Urinary Incontinence Life Threatening 9/15/2008 70 Male 2/27/2009 Pharmacist Switzerland
Primary
Secondary
Concomitant
Tremor 7/25/2000 73 Male 155 lb 4/3/2009 United States
Primary
Concomitant
Urinary Incontinence Life Threatening 9/15/2008 70 Male 4/6/2009 Pharmacist Switzerland
Primary
Concomitant
Interacting
Urinary Incontinence Life Threatening 9/15/2008 70 Male 4/10/2009 Pharmacist Switzerland
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 7/11/2001 63 Male 220 lb 4/20/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/15/2004 49 Male 276 lb 4/21/2009 United States
Primary
Concomitant
Transaminases Increased Other Serious 3/25/2009 Male 201 lb 4/30/2009 Physician Germany
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 8/2/1999 33 Female 125 lb 5/15/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/8/2001 43 Male 240 lb 5/20/2009 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/17/2008 4 6/23/2009 Physician Japan
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 12/1/2008 Female 280 lb 6/26/2009 Physician United States
Primary
Concomitant
Tachycardia Life Threatening 21 Male 7/7/2009 Physician Canada
Primary
Secondary
Concomitant
Tachycardia Life Threatening 21 Male 7/9/2009 Physician Canada
Primary
Secondary
Concomitant
Diabetic Retinopathy Other Serious 6/23/2003 31 Male 248 lb 7/14/2009 United States
Primary
Concomitant
Apnoea Other Serious Male 7/15/2009 Other Health Professional Mexico
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/8/2002 11 Male 70 lb 7/21/2009 United States
Primary
Concomitant
Weight Increased Other Serious 10/28/2002 35 Male 7/22/2009 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/1999 39 Male 258 lb 7/30/2009 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/1/2009 49 Female 252 lb 8/10/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tremor Other Serious Male 8/13/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Vertigo Hospitalization 8/5/2009 Male 8/18/2009 Physician Germany
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/1/2001 38 Female 165 lb 9/2/2009 United States
Primary
Concomitant
Cerebral Infarction Other Serious 8/6/2009 Male 287 lb 9/3/2009 Physician Germany
Primary
Concomitant
Vertigo Hospitalization 8/6/2009 Male 287 lb 9/8/2009 Physician Germany
Primary
Concomitant
Neuropathy Peripheral Other Serious 10/1/2004 47 Female 237 lb 9/14/2009 United States
Primary
Concomitant
Weight Increased 8/4/2003 36 Male 274 lb 9/23/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2003 38 Female 260 lb 9/23/2009 United States
Primary
Concomitant
Tremor 7/25/2000 73 Male 155 lb 9/23/2009 United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2000 41 Female 230 lb 9/23/2009 United States
Primary
Concomitant
Convulsion Other Serious 8/14/2009 47 Male 10/6/2009 Physician Canada
Primary
Concomitant
Vascular Dementia Other Serious 8/21/2004 66 Male 264 lb 10/15/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 51 Male 286 lb 10/15/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 213 lb 11/2/2009 United States
Primary
Concomitant
Transaminases Increased Other Serious 3/25/2009 Male 201 lb 11/6/2009 Physician Germany
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/1/2003 58 Male 199 lb 11/19/2009 United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 9/1/2003 58 Male 199 lb 11/27/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 213 lb 1/25/2010 United States
Primary
Concomitant
Hyponatraemia Hospitalization 7/31/2009 74 Male 147 lb 3/4/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/7/2004 Female 132 lb 3/2/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 12/1/2003 57 Female 183 lb 6/8/2010 United States
Primary
Concomitant
Hypersomnia-bulimia Syndrome Other Serious 18 Male 6/9/2010 United States
Primary
Concomitant
Weight Increased Other Serious 10/28/2002 35 Male 345 lb 7/6/2010 United States
Primary
Concomitant
Erectile Dysfunction Male 200 lb 7/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/1/2003 57 Female 183 lb 7/9/2010 United States
Primary
Concomitant
Weight Increased 3/1/2007 67 Male 184 lb 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2000 57 Female 7/23/2010 Consumer United States
Primary
Concomitant
Irritability 37 8/3/2010 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/25/2000 73 Male 155 lb 8/5/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2000 57 Female 8/11/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/1999 44 Male 235 lb 8/23/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 43 Male 268 lb 8/27/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2000 57 Female 8/27/2010 Consumer United States
Primary
Concomitant
Flushing 8/29/2010 Consumer United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 43 Female 9/7/2010 Other Health Professional Canada
Primary
Concomitant
Interacting
Weight Increased Other Serious 1/1/2000 57 Female 9/13/2010 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2000 41 Female 230 lb 9/20/2010 United States
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/2005 31 Female 234 lb 9/20/2010 United States
Primary
Concomitant
Pain Other Serious Male 10/27/2010 Physician Canada
Primary
Concomitant
Pain Other Serious 9/13/2010 36 Male 11/1/2010 Physician Canada
Primary
Concomitant
Tic Other Serious 6/3/2010 9 Male 11/2/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Paranoia Hospitalization 1/1/2010 63 Female 110 lb 1/30/2011 Consumer United States
Primary
Secondary
Concomitant
Polydipsia Other Serious 11/1/2010 59 Male 2/28/2011 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2010 59 Male 139 lb 3/1/2011 Physician Japan
Primary
Secondary
Concomitant
Erectile Dysfunction Other Serious 1/1/2003 43 Male 210 lb 3/15/2011 United States
Primary
Concomitant
Diabetic Complication Hospitalization 11/1/2003 43 Male 210 lb 3/17/2011 Other Health Professional United States
Primary
Concomitant
Hydrocephalus Other Serious 1/1/2010 47 Male 240 lb 3/18/2011 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/1/2010 59 Male 139 lb 3/24/2011 Physician Japan
Primary
Secondary
Concomitant
Injection Site Pain Other Serious 1/1/2010 37 Male 280 lb 3/28/2011 Consumer United States
Primary
Secondary
Concomitant
Polydipsia Other Serious 11/1/2010 59 Male 139 lb 4/1/2011 Physician Japan
Primary
Secondary
Concomitant
Erectile Dysfunction Hospitalization 1/1/2002 42 Male 210 lb 4/8/2011 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 9/1/2004 61 Female 5/3/2011 Consumer Canada
Primary
Concomitant
Hypercholesterolaemia Other Serious Male 228 lb 5/23/2011 Physician Canada
Primary
Concomitant
Blood Prolactin Increased Hospitalization 1/1/2011 27 Female 6/3/2011 Physician Austria
Primary
Secondary
Concomitant
Galactorrhoea Other Serious 1/1/2011 27 Female 6/9/2011 Physician Austria
Primary
Secondary
Concomitant
Leukopenia Life Threatening 1/1/2011 27 Female 6/12/2011 Physician Austria
Primary
Secondary
Concomitant
Hypotension Death 12/21/2005 57 Female 6/15/2011 Pharmacist Canada
Primary
Concomitant
Oesophageal Obstruction Other Serious 81 Female 6/27/2011 Pharmacist Switzerland
Primary
Concomitant
Clumsiness Other Serious 51 Female 191 lb 6/24/2011 Lawyer United States
Primary
Concomitant
Hyperprolactinaemia Other Serious 1/1/2005 39 Female 7/28/2011 Other Health Professional France
Primary
Concomitant
Tooth Loss Other Serious 10/28/2002 35 Male 345 lb 7/28/2011 Consumer United States
Primary
Concomitant
Pneumonia Death 11/18/2005 57 Female 188 lb 8/1/2011 Physician Canada
Primary
Concomitant
Confusional State Hospitalization 6/8/2011 5 Male 8/10/2011 Pharmacist Japan
Primary
Concomitant
Dysphonia Hospitalization 6/6/2011 6 Male 42 lb 8/18/2011 Other Health Professional Japan
Primary
Concomitant
Overdose Other Serious 5/23/2006 56 Female 245 lb 8/22/2011 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/29/2011 63 Female 9/12/2011 Other Health Professional France
Primary
Secondary
Concomitant
Cognitive Disorder Hospitalization 43 Male 9/12/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Diabetes Mellitus Other Serious 1/1/2005 31 Female 234 lb 9/22/2011 Other Health Professional United States
Primary
Concomitant
Parkinsonism Hospitalization 8/10/2011 87 Male 10/3/2011 Other Health Professional France
Primary
Secondary
Concomitant
Off Label Use Hospitalization 7/25/2011 87 Male 10/4/2011 Consumer France
Primary
Concomitant
Ileus Death 1/1/2008 38 Male 10/14/2011 Physician Japan
Primary
Secondary
Apallic Syndrome Hospitalization Male 10/24/2011 Physician Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 38 Male 10/14/2011 Consumer Japan
Primary
Concomitant
Respiratory Depression Death 1/1/2007 38 Male 10/25/2011 Consumer Japan
Primary
Concomitant
Overdose Other Serious Female 10/20/2011 Consumer New Zealand
Primary
Concomitant
Self Injurious Behaviour Other Serious 10/22/2011 38 Male 11/11/2011 Physician Italy
Primary
Secondary
Abnormal Faeces Hospitalization 6/26/2007 38 Male 181 lb 12/8/2011 Physician Japan
Primary
Secondary
Concomitant
Ileus Paralytic Life Threatening 6/28/2007 38 Male 181 lb 12/9/2011 Physician Japan
Primary
Concomitant
Interacting
Intestinal Obstruction Hospitalization 6/26/2007 38 Male 181 lb 12/14/2011 Physician Japan
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 56 Male 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 56 Male 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 56 Male 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 10/29/2011 80 Male 12/16/2011 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/28/2007 38 Male 181 lb 12/16/2011 Physician Japan
Primary
Concomitant
Interacting

Drug Data