Remifentanil combined with Sevoflurane

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somatosensory Evoked Potentials Abnormal Other Serious 7 Female 97 lb 5/20/2006 Australia
Primary
Concomitant
Vomiting Other Serious 65 Male 6/20/2006 United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 82 Female 132 lb 8/1/2006 Consumer Spain
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/22/2005 65 Male 176 lb 8/4/2006 United Kingdom
Primary
Concomitant
Neuromuscular Block Prolonged Hospitalization 4/24/2006 32 Female 8/11/2006 South Africa
Primary
Concomitant
Metabolic Acidosis Other Serious 32 Female 2/16/2007 Physician United Kingdom
Primary
Concomitant
Acute Coronary Syndrome Other Serious 71 Male 174 lb 9/19/2007 Brazil
Primary
Concomitant
Respiratory Distress Hospitalization 11/9/2007 Physician New Zealand
Primary
Concomitant
Rhabdomyolysis Life Threatening 1 Male 9 lb 11/15/2007 United States
Primary
Secondary
Concomitant
Respiratory Depression Life Threatening 53 Female 128 lb 11/19/2007
Primary
Secondary
Concomitant
Myocardial Ischaemia Life Threatening 45 Male 214 lb 12/5/2007 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 1 Male 9 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Hypotension Other Serious 71 Male 174 lb 12/21/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 53 Female 128 lb 1/18/2008 New Zealand
Primary
Concomitant
Vomiting Other Serious 7/22/2005 65 Male 176 lb 3/1/2008 United Kingdom
Primary
Concomitant
Serotonin Syndrome Hospitalization 65 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 65 Male 3/13/2008 United Kingdom
Primary
Secondary
Concomitant
Hyperaesthesia Other Serious 46 Female 139 lb 5/30/2008 Spain
Primary
Secondary
Concomitant
Vomiting Other Serious 7/22/2008 65 Male 176 lb 8/13/2008 United Kingdom
Primary
Concomitant
Interacting
Cerebrovascular Accident Death 9/5/2008
Primary
Secondary
Concomitant
Tremor Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 47 Female 11/5/2008 Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 47 Female 11/17/2008 Japan
Primary
Secondary
Concomitant
Vocal Cord Disorder Other Serious 11/18/2008 Japan
Primary
Concomitant
Vocal Cord Disorder Other Serious 11/18/2008 Japan
Primary
Concomitant
Vocal Cord Disorder Other Serious 11/18/2008 Japan
Primary
Concomitant
Myasthenia Gravis Hospitalization 76 Female 12/2/2008 Japan
Primary
Concomitant
Vocal Cord Disorder Other Serious 57 Female 143 lb 12/10/2008 Japan
Primary
Concomitant
Vocal Cord Disorder Other Serious 43 Female 126 lb 12/10/2008 Japan
Primary
Concomitant
Vocal Cord Disorder Other Serious 54 Female 123 lb 12/10/2008 Japan
Primary
Concomitant
Circulatory Collapse Other Serious 2 Female 12/11/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 2 Female 23 lb 12/15/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Myasthenia Gravis Hospitalization 76 Female 12/16/2008 Japan
Primary
Concomitant
Tachycardia Other Serious 1/10/2006 64 Female 1/23/2009 Physician France
Primary
Secondary
Rash Hospitalization 6/11/2008 Female 1/26/2009 Physician France
Primary
Secondary
Concomitant
Electromechanical Dissociation Life Threatening 1/1/2008 2 Female 23 lb 1/29/2009 Physician Canada
Primary
Secondary
Anaphylactic Shock Life Threatening 5/29/2008 42 Male 3/2/2009 Other Health Professional France
Primary
Secondary
Overdose Other Serious 2 Male 24 lb 3/4/2009 Physician Germany
Primary
Concomitant
Respiratory Acidosis Other Serious 60 Male 4/13/2009
Primary
Secondary
Tracheomalacia Other Serious 7/18/2006 Male 5 lb 4/16/2009 Physician Germany
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 3/23/2007 60 Male 7/23/2009
Primary
Secondary
Serotonin Syndrome Hospitalization 65 Male 8/26/2009 United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 11/8/2008 81 Male 132 lb 9/2/2009 Physician Japan
Primary
Concomitant
Electromechanical Dissociation Required Intervention 2 Female 23 lb 9/3/2009 Physician Canada
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 35 Female 106 lb 10/6/2009 Japan
Primary
Concomitant
Ventricular Arrhythmia Other Serious 80 Female 121 lb 10/15/2009 Japan
Primary
Secondary
Concomitant
Hepatitis Toxic Other Serious 9/28/2009 43 Female 10/19/2009 Physician Turkey
Primary
Concomitant
Status Epilepticus Other Serious 35 Female 106 lb 10/19/2009 Japan
Primary
Concomitant
Ventricular Arrhythmia Other Serious 80 Female 121 lb 10/23/2009 Japan
Primary
Secondary
Concomitant
Bundle Branch Block Other Serious 17 Female 10/26/2009 Japan
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 3/25/2009 Female 106 lb 11/5/2009 Japan
Primary
Concomitant
Urinary Retention Other Serious 29 Female 123 lb 11/9/2009 Physician France
Primary
Secondary
Ventricular Hypokinesia Other Serious 11/11/2009 United States
Primary
Secondary
Cardiac Arrest Other Serious 11/11/2009 United States
Primary
Secondary
Salivary Gland Enlargement Other Serious 67 Female 11/11/2009 Japan
Primary
Secondary
Concomitant
Resuscitation Life Threatening 11/12/2009 Other Health Professional United States
Primary
Secondary
Resuscitation Life Threatening 11/12/2009 Other Health Professional United States
Primary
Secondary
Salivary Gland Enlargement Other Serious 67 Female 11/18/2009 Japan
Primary
Secondary
Concomitant
Salivary Gland Enlargement Other Serious 67 Female 11/23/2009 Japan
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 11/23/2009 Physician United States
Primary
Secondary
Bundle Branch Block Other Serious 17 Female 12/2/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Epilepsy Other Serious 3/25/2009 Female 106 lb 12/3/2009 Japan
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 3/25/2009 Female 106 lb 12/8/2009 Japan
Primary
Secondary
Concomitant
Bundle Branch Block Other Serious 17 Female 12/11/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Sensorimotor Disorder Other Serious 29 Female 123 lb 12/28/2009 Physician France
Primary
Concomitant
Tremor Life Threatening 65 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 65 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 65 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 11/11/2008 59 Female 3/29/2010 Japan
Primary
Concomitant
Respiratory Depression Hospitalization 74 Female 4/12/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 74 Female 84 lb 4/21/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Torsade De Pointes Other Serious 11/4/2008 59 Female 95 lb 4/30/2010 Japan
Primary
Secondary
Concomitant
Upper Airway Obstruction Hospitalization 1/1/2009 74 Female 84 lb 5/13/2010 Other Health Professional Japan
Primary
Secondary
Ventricular Extrasystoles Other Serious 11/4/2008 59 Female 95 lb 5/28/2010 Japan
Primary
Concomitant
Troponin Increased Other Serious 6/22/2010 Other Health Professional United States
Primary
Concomitant
Drug Interaction Other Serious 66 Female 7/5/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 66 Female 99 lb 8/5/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stress Cardiomyopathy Other Serious 67 Female 159 lb 8/6/2010 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11 Female 77 lb 8/13/2010 Consumer Canada
Primary
Concomitant
Ventricular Tachycardia Other Serious 11 Female 77 lb 8/27/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11 Female 9/3/2010 Physician Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11 Female 9/7/2010 Physician Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11 Female 9/8/2010 Physician Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11 Female 9/8/2010 Physician Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11 Female 77 lb 9/9/2010
Primary
Secondary
White Blood Cell Count Increased Other Serious 22 Female 78 lb 9/13/2010 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/22/2009 22 Female 77 lb 9/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 68 Male 141 lb 10/8/2010 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 68 Male 141 lb 10/19/2010 Physician Japan
Primary
Concomitant
Hypotonia Other Serious 76 Female 128 lb 10/20/2010 Physician Japan
Primary
Concomitant
Hypotonia Other Serious 76 Female 128 lb 11/9/2010 Physician Japan
Primary
Concomitant
Convulsion Other Serious 45 Female 134 lb 12/20/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Trismus Other Serious 8 Female 49 lb 12/8/2010 Physician Japan
Primary
Secondary
Trismus Other Serious 8 Female 49 lb 12/21/2010 Japan
Primary
Secondary
Ventricular Tachycardia Hospitalization 11 Female 1/28/2011 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious Female 3/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Diabetes Insipidus Death Female 3/11/2011 Physician United Kingdom
Primary
Secondary
Anaphylactic Reaction Life Threatening 54 Male 154 lb 3/9/2011 Physician Turkey
Primary
Concomitant
Encephalopathy Hospitalization 12 Female 88 lb 4/22/2011 Physician Canada
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 2 Female 23 lb 4/25/2011 Canada
Primary
Secondary
Concomitant
Dyspnoea Other Serious 6/22/2009 22 Female 77 lb 4/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Bradycardia Hospitalization 42 Male 187 lb 5/23/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Skin Lesion Other Serious 56 Male 7/19/2011 Other Health Professional France
Primary
Concomitant
Compartment Syndrome Other Serious 43 Male 8/16/2011 Physician United States
Primary
Secondary
Concomitant
Compartment Syndrome Other Serious 43 Male 154 lb 8/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Compartment Syndrome Other Serious 43 Male 154 lb 9/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 36 Female 122 lb 9/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 36 Female 122 lb 9/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 36 Female 122 lb 9/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 60 Female 9/29/2011 Other Health Professional Japan
Primary
Concomitant
Blood Pressure Decreased Other Serious 36 Female 122 lb 10/4/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 64 Male 104 lb 10/5/2011 Other Health Professional Japan
Primary
Concomitant
Respiratory Depression Hospitalization 74 Female 84 lb 10/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 4/28/2011 64 Male 104 lb 10/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 60 Female 10/10/2011 Other Health Professional Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 4/28/2011 64 Male 104 lb 10/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 80 Female 121 lb 10/17/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Arrhythmia Life Threatening 80 Female 121 lb 11/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Long Qt Syndrome Other Serious 80 Female 121 lb 11/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypotension Hospitalization 58 Male 11/8/2011 Physician United States
Primary
Secondary
Electrocardiogram St Segment Elevation Other Serious 38 Male 11/9/2011 Physician United States
Primary
Secondary
Anaphylactic Shock Other Serious 68 Male 11/11/2011 Other Health Professional Japan
Primary
Secondary
Toxicity To Various Agents Other Serious 36 Female 146 lb 11/11/2011 Other Health Professional Japan
Primary
Concomitant
Stress Cardiomyopathy Life Threatening Male 11/21/2011 Other Health Professional Japan
Primary
Concomitant
Electrocardiogram St Segment Elevation Other Serious 38 Male 11/23/2011 Physician United States
Primary
Secondary
Cardiac Arrest Life Threatening Male 12/5/2011 Other Health Professional Japan
Primary
Concomitant
Anaphylactic Shock Other Serious 68 Male 12/9/2011 Other Health Professional Japan
Primary
Concomitant
Cardiac Arrest Life Threatening 12/1/2010 50 Male 149 lb 12/13/2011 Other Health Professional Japan
Primary
Concomitant
Stress Cardiomyopathy Life Threatening 12/1/2010 50 Male 149 lb 12/15/2011 Other Health Professional Japan
Primary
Concomitant
Delayed Recovery From Anaesthesia Hospitalization 1/27/2011 76 Female 105 lb 12/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia Hospitalization 1/27/2011 76 Female 105 lb 12/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia Hospitalization 1/27/2011 76 Female 105 lb 12/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia Hospitalization 1/27/2011 76 Female 105 lb 12/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Cardiomyopathy Hospitalization 1/27/2011 76 Female 105 lb 12/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia Hospitalization 1/27/2011 76 Female 105 lb 12/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 11 Female 77 lb 1/10/2012 Physician Canada
Primary
Concomitant
Interacting
Atrioventricular Block Second Degree Hospitalization 12/22/2011 69 Female 88 lb 1/20/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Encephalopathy Life Threatening 15 Male 138 lb 2/6/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Status Asthmaticus Life Threatening 24 Male 2/10/2012 Other Health Professional China
Primary
Concomitant
Anaphylactic Reaction Other Serious 61 Female 99 lb 5/22/2012 Other Health Professional France
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Other Serious 67 Female 7/27/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Other Serious 67 Female 104 lb 8/14/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Reye's Syndrome Other Serious 15 Male 138 lb 9/28/2012 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Reye's Syndrome Hospitalization 15 Male 139 lb 9/13/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Shock Haemorrhagic Hospitalization 65 Female 11/9/2012 Physician Jp
Primary
Secondary
Concomitant
Pneumonia Other Serious 32 Male 112 lb 11/20/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Uterine Hypotonus Other Serious 36 Female 11/21/2012 Physician It
Primary
Secondary
Concomitant
Uterine Hypotonus Other Serious 36 Female 11/29/2012 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant

Drug Data