Rebif combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Swelling Hospitalization 10/28/2005 34 Male 1/25/2006 Pharmacist United States
Primary
Secondary
Oxygen Saturation Decreased Other Serious Female 147 lb 3/22/2006 United States
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 4/3/2006 29 Female 5/10/2006 United States
Primary
Concomitant
Somnolence Life Threatening 7/4/2005 36 Female 118 lb 5/22/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 96 lb 6/2/2006 Physician United States
Primary
Concomitant
Suicide Attempt Life Threatening 1/1/2006 48 Female 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Multiple Sclerosis Other Serious Female 96 lb 6/2/2006 Physician United States
Primary
Concomitant
Ejection Fraction Decreased Other Serious 4/12/2006 39 Female 132 lb 6/15/2006 United States
Primary
Concomitant
Vomiting Other Serious 11/1/2005 42 Female 168 lb 6/19/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence Life Threatening 7/4/2005 36 Female 118 lb 6/16/2006 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/15/2006 33 Female 229 lb 7/6/2006 United States
Primary
Concomitant
Tunnel Vision Hospitalization 7/1/2006 40 Female 9/8/2006 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 7/4/2005 36 Female 118 lb 9/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Intentional Self-injury Other Serious 1/1/2006 40 Female 10/16/2006 United States
Primary
Secondary
Meningitis Viral Hospitalization 5/25/2006 Female 10/19/2006 Canada
Primary
Concomitant
Rash Hospitalization 11/10/2005 34 Male 8/18/2006 Physician United States
Primary
Secondary
Suicide Attempt Other Serious 7/1/2005 36 Female 118 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 2/26/2006 48 Female 8/18/2006 United States
Primary
Secondary
Suicidal Ideation Hospitalization 1/1/2006 47 Female 203 lb 12/21/2006 Other Health Professional United States
Primary
Concomitant
Hypokalaemia Other Serious 6/1/2006 33 Female 260 lb 1/19/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2006 Female 227 lb 2/26/2007 Other Health Professional United States
Primary
Concomitant
Malignant Melanoma Other Serious 1/1/2007 48 Female 3/9/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2006 Female 227 lb 3/23/2007 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 8/18/2006 38 Male 3/8/2007 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 32 Female 3/20/2007 United States
Primary
Concomitant
Malignant Melanoma Other Serious 1/1/2007 48 Female 3/21/2007 Physician United States
Primary
Concomitant
No Adverse Effect 52 Female 3/26/2007 United States
Primary
Concomitant
Ketoacidosis Hospitalization 12/13/2006 49 Female 150 lb 4/4/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2007 Female 158 lb 4/13/2007 Consumer United States
Primary
Concomitant
Convulsion Hospitalization 3/13/2007 40 Female 4/9/2007 United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2007 32 Female 4/16/2007 United States
Primary
Concomitant
Pain Hospitalization 3/14/2007 48 Female 140 lb 4/19/2007 United States
Primary
Concomitant
Calcinosis Other Serious 1/1/2007 32 Female 4/23/2007 United States
Primary
Concomitant
Suicidal Ideation Required Intervention 1/1/2007 32 Female 4/24/2007 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2007 54 Female 5/1/2007 United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 3/14/2007 48 Female 140 lb 5/3/2007 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 3/1/2007 45 Female 5/8/2007 United States
Primary
Secondary
Infection Hospitalization 10/1/2006 43 Female 169 lb 5/10/2007 United States
Primary
Concomitant
Vomiting Hospitalization 6/8/2006 43 Female 169 lb 5/10/2007 United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 1/26/2007 Female 5/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 38 Female 5/14/2007 United States
Primary
Concomitant
Loss Of Consciousness Other Serious 3/1/2007 Female 5/22/2007 Consumer United States
Primary
Secondary
Syncope Other Serious 8/1/2006 38 Male 240 lb 6/18/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2005 51 Female 85 lb 6/18/2007 United States
Primary
Concomitant
Syncope Vasovagal Other Serious 7/28/2006 38 Male 240 lb 6/26/2007 Physician United States
Primary
Concomitant
Vertigo Other Serious 3/1/2007 37 Female 6/27/2007 United States
Primary
Concomitant
Vertigo Other Serious 3/1/2007 37 Female 215 lb 7/5/2007 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 5/1/2007 25 Female 7/16/2007 United States
Primary
Secondary
Concomitant
Tongue Disorder Other Serious 5/22/2007 52 Female 212 lb 7/17/2007 United States
Primary
Concomitant
Diabetes Mellitus Other Serious 6/1/2007 46 Female 175 lb 7/30/2007 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2004 59 Female 170 lb 9/13/2007 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2004 59 Female 170 lb 9/20/2007 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 10/1/2006 45 Female 125 lb 10/18/2007 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Disorder Other Serious 9/1/2007 27 Female 10/26/2007 United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 7/1/2007 32 Female 223 lb 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Multi-organ Disorder Hospitalization 9/1/2007 27 Female 11/15/2007 United States
Primary
Concomitant
Thyroid Cancer Other Serious 1/1/2007 27 Female 11/15/2007 United States
Primary
Concomitant
Sepsis Hospitalization 7/8/2007 58 Male 270 lb 12/5/2007 Consumer United States
Primary
Concomitant
Cognitive Disorder 1/1/2007 26 Male 12/10/2007 United States
Primary
Concomitant
Muscle Spasms Hospitalization 10/1/2007 27 Female 204 lb 12/14/2007 Physician United States
Primary
Concomitant
Phaeochromocytoma Other Serious 1/1/2007 49 Female 1/2/2008 United States
Primary
Concomitant
Myalgia Other Serious 3/26/2007 52 Female 4/26/2007 Physician United States
Primary
Concomitant
Norepinephrine Increased Other Serious 1/1/2007 49 Female 287 lb 1/11/2008 United States
Primary
Concomitant
Convulsion Other Serious 12/1/2007 27 Female 1/11/2008 United States
Primary
Concomitant
Diabetes Mellitus Other Serious 6/1/2007 46 Female 175 lb 1/22/2008 Other Health Professional United States
Primary
Concomitant
Low Density Lipoprotein Increased Other Serious 5/1/2007 67 Female 121 lb 1/23/2008 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 1/12/2008 49 Female 140 lb 1/23/2008 United States
Primary
Concomitant
Glioma Other Serious 9/1/2007 15 Female 110 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Osteoarthritis Other Serious 1/1/2007 37 Female 2/12/2008 United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2006 Female 158 lb 2/25/2008 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 3/1/2007 48 Female 140 lb 2/27/2008 United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2006 36 Female 187 lb 3/10/2008 United States
Primary
Concomitant
Sciatica Hospitalization 1/28/2008 47 Female 265 lb 3/10/2008 United States
Primary
Concomitant
Dizziness Other Serious 3/6/2008 51 Female 168 lb 3/13/2008 United States
Primary
Concomitant
Bronchospasm Other Serious 1/1/2008 28 Female 3/20/2008 United States
Primary
Concomitant
Ischaemia Other Serious 1/1/2008 50 Female 3/25/2008 United States
Primary
Concomitant
Dizziness Other Serious 2/1/2008 28 Female 240 lb 3/28/2008 United States
Primary
Concomitant
Diabetes Mellitus Other Serious 3/17/2008 51 Female 168 lb 3/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 3/20/2008 42 Female 185 lb 4/1/2008 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 2/1/2008 43 Female 4/3/2008 United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 2/21/2008 50 Female 170 lb 4/2/2008 United States
Primary
Concomitant
Swelling Face Other Serious 3/20/2008 42 Female 185 lb 4/9/2008 Other Health Professional United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2008 31 Female 4/11/2008 United States
Primary
Concomitant
Pyrexia Hospitalization 7/7/2007 58 Male 270 lb 4/14/2008 United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2006 Female 158 lb 5/15/2008 Physician United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 1/1/2008 31 Female 5/20/2008 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 1/12/2008 49 Female 140 lb 5/21/2008 United States
Primary
Concomitant
Convulsion 35 Female 103 lb 5/27/2008 United States
Primary
Concomitant
Paraesthesia Hospitalization 9/1/2007 42 Female 5/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Panic Reaction Hospitalization 6/22/2007 35 Female 130 lb 5/1/2008 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 11/7/2007 30 Female 190 lb 5/1/2008 United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2006 Female 158 lb 6/10/2008 Physician United States
Primary
Concomitant
Multiple Sclerosis Relapse Other Serious 3/1/2008 33 Female 6/13/2008 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 12/1/2007 27 Female 6/20/2008 Other Health Professional United States
Primary
Concomitant
Thyroid Mass 1/1/2007 27 Female 6/24/2008 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 3/1/2007 Female 116 lb 7/2/2008 Consumer United States
Primary
Secondary
Concomitant
Peroneal Nerve Palsy Hospitalization 3/17/2008 47 Female 130 lb 7/11/2008 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/31/2008 27 Female 155 lb 7/28/2008 Physician United States
Primary
Concomitant
Tremor Other Serious 6/29/2008 49 Female 160 lb 7/25/2008 United States
Primary
Concomitant
Knee Arthroplasty 2/1/2007 51 Female 155 lb 8/8/2008 United States
Primary
Concomitant
Splenomegaly Other Serious 8/1/2008 26 Female 260 lb 8/19/2008 United States
Primary
Concomitant
Condition Aggravated Other Serious 38 Female 215 lb 8/22/2008 United States
Primary
Concomitant
Memory Impairment Other Serious 38 Female 215 lb 9/2/2008 Other Health Professional United States
Primary
Concomitant
Treatment Noncompliance Other Serious 8/1/2008 54 Female 190 lb 9/2/2008 United States
Primary
Concomitant
Splenomegaly Other Serious 8/1/2008 26 Female 260 lb 9/2/2008 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 1/12/2008 49 Female 140 lb 9/4/2008 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 8/19/2008 32 Female 9/15/2008 United States
Primary
Concomitant
Splenomegaly Other Serious 8/1/2008 26 Female 260 lb 9/15/2008 United States
Primary
Concomitant
Stress Hospitalization 2/1/2008 50 Female 121 lb 9/25/2008 United States
Primary
Concomitant
Stress Hospitalization 7/1/2008 39 Female 9/29/2008 United States
Primary
Concomitant
Pneumonia Aspiration Life Threatening 6/6/2008 53 Female 10/3/2008 United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 9/1/2007 40 Female 362 lb 10/10/2008 United States
Primary
Concomitant
Suicide Attempt Hospitalization 1/1/2008 40 Female 10/8/2008 United States
Primary
Secondary
Lymphoproliferative Disorder Other Serious 3/1/2008 53 Female 112 lb 10/13/2008 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2008 Male 10/24/2008 Consumer Canada
Primary
Secondary
Concomitant
Interacting
Small Intestinal Obstruction Hospitalization 9/1/2007 40 Female 362 lb 10/17/2008 United States
Primary
Concomitant
Suicide Attempt Hospitalization 9/1/2008 40 Female 10/23/2008 United States
Primary
Secondary
Multiple Sclerosis Other Serious 8/1/2008 22 Female 185 lb 10/28/2008 United States
Primary
Concomitant
Suicide Attempt Hospitalization 9/1/2008 40 Female 10/27/2008 United States
Primary
Secondary
Multiple Sclerosis Hospitalization 5/23/2008 43 Male 238 lb 10/27/2008 United States
Primary
Concomitant
Vascular Calcification Other Serious 2/21/2008 50 Female 170 lb 10/31/2008 United States
Primary
Concomitant
Suicide Attempt Other Serious 9/1/2008 Female 11/13/2008 Consumer United States
Primary
Concomitant
Intentional Self-injury Hospitalization 1/1/2006 Female 11/14/2008 Consumer United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/1/2008 43 Female 11/12/2008 United States
Primary
Concomitant
Intentional Self-injury Hospitalization 1/1/2006 Female 11/18/2008 Consumer United States
Primary
Concomitant
Vomiting 1/1/2008 29 Female 11/14/2008 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/1/2008 36 Female 243 lb 12/1/2008 United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious 56 Female 12/2/2008 United States
Primary
Concomitant
Renal Failure Chronic Other Serious 56 Female 134 lb 12/9/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2007 30 Female 190 lb 12/9/2008 United States
Primary
Concomitant
Myelitis Transverse 9/1/2008 12/10/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 8/24/2007 56 Female 137 lb 12/17/2008 Other Health Professional United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 8/19/2008 32 Female 12/17/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2008 53 Male 247 lb 12/22/2008 United States
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 3/1/2008 53 Female 112 lb 12/22/2008 Consumer United States
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 11/1/2008 45 Female 1/2/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2008 54 Female 130 lb 1/12/2009 United States
Primary
Concomitant
Immune System Disorder Other Serious 1/2/2009 45 Female 190 lb 1/16/2009 United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2008 53 Male 265 lb 1/26/2009 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 11/1/2008 43 Female 1/27/2009 United States
Primary
Concomitant
Immune System Disorder Other Serious 1/2/2009 45 Female 190 lb 1/29/2009 United States
Primary
Concomitant
Off Label Use Other Serious 6/1/2008 26 Male 1/16/2009 Physician United States
Primary
Concomitant
Peroneal Nerve Palsy Other Serious 3/21/2008 47 Female 130 lb 2/3/2009 United States
Primary
Concomitant
Hepatic Steatosis Other Serious 1/1/2009 48 Female 265 lb 2/5/2009 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2009 56 Female 209 lb 2/10/2009 United States
Primary
Secondary
Concomitant
Pruritus Other Serious 12/31/2008 Female 3/18/2009 Physician United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 2/26/2009 27 Female 3/19/2009 United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2008 53 Male 265 lb 3/27/2009 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 2/1/2009 31 Female 201 lb 3/25/2009 United States
Primary
Concomitant
Hepatitis Other Serious 1/1/2009 48 Female 265 lb 4/3/2009 United States
Primary
Secondary
Concomitant

Drug Data