Rabeprazole Sodium combined with Zolpidem

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Leukoencephalopathy Other Serious 12/5/2006 70 Female 9/3/2007 Pharmacist Japan
Primary
Secondary
White Blood Cell Count Increased Life Threatening 8/3/2007 68 Male 88 lb 9/5/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/15/2006 71 Male 9/7/2007 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 8/3/2007 68 Male 88 lb 9/12/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 8/3/2007 68 Male 88 lb 10/22/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 9/24/2007 73 Male 150 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 9/24/2007 73 Male 150 lb 11/6/2007 Physician Japan
Primary
Secondary
Concomitant
Plasmacytosis Other Serious Female 9/17/2008 Pharmacist Belgium
Primary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization Male 141 lb 11/25/2008 Korea, Republic Of
Primary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 9/18/2008 1/20/2009 Physician Korea, Republic Of
Primary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 9/18/2008 1/21/2009 Physician Korea, Republic Of
Primary
Concomitant
White Blood Cell Count Increased Death 12/19/2008 80 Male 149 lb 3/4/2009 Physician Japan
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 34 Female 1/25/2010 Physician United States
Primary
Secondary
Completed Suicide Death 12/1/2009 34 Female 2/1/2010 Physician United States
Primary
Secondary
Completed Suicide Death 34 Female 2/23/2010 Physician United States
Primary
Secondary
Condition Aggravated Hospitalization 9/25/2008 51 Male 141 lb 6/11/2010 Physician Korea, Republic Of
Primary
Concomitant
Haemoptysis Hospitalization 6/3/2010 63 Female 119 lb 6/18/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 6/3/2010 63 Female 119 lb 6/22/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/18/2008 80 Male 149 lb 6/23/2010 Physician Japan
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 6/3/2010 63 Female 119 lb 7/14/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 6/3/2010 63 Female 119 lb 7/30/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 6/3/2010 63 Female 119 lb 8/9/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 6/3/2010 63 Female 119 lb 8/25/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Epistaxis Hospitalization 1/1/2010 72 Male 8/26/2010 Other Health Professional France
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2008 34 Female 10/28/2010 Other Health Professional United States
Primary
Secondary
Tremor Other Serious 1/1/2009 52 Male 190 lb 10/27/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/8/2010 60 Female 11/23/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/8/2010 60 Female 12/15/2010 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/16/2011 63 Female 99 lb 5/20/2011 Other Health Professional Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/13/2011 72 Male 112 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Mechanical Ileus Hospitalization 4/24/2011 82 Female 134 lb 5/26/2011 Physician Japan
Primary
Concomitant
Haemoptysis Hospitalization 6/3/2010 63 Female 119 lb 5/27/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 3/21/2011 89 Female 5/19/2011 Physician France
Primary
Concomitant
Cholangitis Life Threatening 7/21/2010 55 Male 176 lb 6/2/2011 Physician Japan
Primary
Concomitant
International Normalised Ratio Increased Other Serious 1/24/2011 84 Female 6/2/2011 Other Health Professional France
Primary
Concomitant
Interacting
Anaemia Hospitalization 1/17/2011 84 Female 6/9/2011 Other Health Professional France
Primary
Concomitant
Interacting
Lung Disorder Hospitalization 3/29/2011 72 Female 6/10/2011 Other Health Professional Japan
Primary
Concomitant
Nausea Hospitalization 12/28/2010 38 Female 6/14/2011 Physician Japan
Primary
Secondary
Concomitant
Pseudoaldosteronism Other Serious 86 Male 119 lb 6/15/2011 Physician Japan
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 2/6/2010 74 Female 106 lb 6/20/2011 Consumer Japan
Primary
Secondary
Concomitant
Blindness Transient Disability 12/7/2010 59 Female 6/22/2011 Other Health Professional Japan
Primary
Concomitant
Multi-organ Failure Death 7/26/2010 70 Female 6/23/2011 Other Health Professional Japan
Primary
Concomitant
Dislocation Of Vertebra Hospitalization 12/3/2010 80 Female 90 lb 6/27/2011 Consumer Japan
Primary
Concomitant
Pseudoaldosteronism Other Serious 86 Male 119 lb 7/1/2011 Physician Japan
Primary
Secondary
Concomitant
Viral Infection Life Threatening 10/8/2007 57 Male 205 lb 7/6/2011 Physician Japan
Primary
Concomitant
Venous Thrombosis Other Serious 5/20/2011 75 Female 154 lb 7/11/2011 Other Health Professional France
Primary
Concomitant
Cholangitis Acute Other Serious 5/3/2010 76 Male 7/12/2011 Physician Japan
Primary
Concomitant
Pseudoaldosteronism Other Serious 86 Male 119 lb 7/12/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Death 8/31/2010 61 Male 115 lb 7/11/2011 Physician Japan
Primary
Concomitant
Nausea Hospitalization 12/28/2010 38 Female 7/14/2011 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 4/24/2011 77 Male 7/14/2011 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 12/28/2010 38 Female 7/20/2011 Physician Japan
Primary
Secondary
Concomitant
Intentional Drug Misuse Death 1/1/2008 34 Female 7/21/2011 Physician United States
Primary
Secondary
Encephalitis Fungal Death Male 139 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 6/10/2011 64 Male 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 12/3/2010 80 Female 90 lb 8/3/2011 Consumer Japan
Primary
Concomitant
Hypokalaemia Other Serious 3/10/2011 52 Female 8/8/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 12/3/2010 41 Female 8/12/2011 Consumer Italy
Primary
Concomitant
Colitis Microscopic Other Serious 6/10/2011 68 Female 8/12/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Other Serious 5/23/2011 77 Male 8/16/2011 Other Health Professional Japan
Primary
Concomitant
Enterocolitis Hospitalization 8/8/2011 70 Male 124 lb 8/22/2011 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/16/2011 63 Female 99 lb 9/2/2011 Other Health Professional Japan
Primary
Concomitant
Enterocolitis Hospitalization 8/8/2011 70 Male 124 lb 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Enterocolitis Hospitalization 8/8/2011 70 Male 124 lb 9/6/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/3/2010 41 Female 9/7/2011 Consumer Italy
Primary
Concomitant
Dislocation Of Vertebra Hospitalization 12/3/2010 80 Female 90 lb 9/13/2011 Consumer Japan
Primary
Concomitant
Pneumonia Hospitalization 7/28/2011 90 Female 82 lb 9/13/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 1/1/2011 84 Female 9/15/2011 Other Health Professional France
Primary
Concomitant
Interacting
Chalazion Other Serious 7/7/2010 37 Male 123 lb 9/19/2011 Physician Japan
Primary
Concomitant
Muscle Spasms Other Serious 8/1/2010 65 Male 9/20/2011 Physician
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/1/2011 84 Female 9/19/2011 Other Health Professional France
Primary
Concomitant
Interacting
Pneumonia Hospitalization 7/1/2011 90 Female 82 lb 9/21/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 9/9/2011 64 Male 9/21/2011 Pharmacist Japan
Primary
Concomitant
Cerebral Haemorrhage Other Serious 9/8/2011 70 Male 106 lb 9/23/2011 Physician Japan
Primary
Concomitant
Enterocolitis Hospitalization 8/8/2011 70 Male 124 lb 9/26/2011 Physician Japan
Primary
Secondary
Concomitant
Erythema Other Serious 8/19/2011 88 Female 9/27/2011 Other Health Professional France
Primary
Concomitant
Nephrotic Syndrome Other Serious 9/14/2010 42 Female 98 lb 9/23/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 5/1/2011 71 Female 132 lb 10/7/2011 Physician France
Primary
Concomitant
Interacting
Pruritus Other Serious 9/21/2010 65 Female 84 lb 10/7/2011 Physician Japan
Primary
Concomitant
Sepsis Death 11/7/2010 59 Male 99 lb 10/10/2011 Physician Japan
Primary
Concomitant
Convulsion Death 7/30/2011 75 Male 84 lb 10/3/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 6/20/2011 73 Female 10/11/2011 Physician Japan
Primary
Concomitant
Chalazion Other Serious 7/7/2010 37 Male 123 lb 10/17/2011 Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 9/9/2011 64 Male 10/19/2011 Pharmacist Japan
Primary
Concomitant
Brain Neoplasm Other Serious 10/11/2011 50 Male 10/20/2011 Physician Japan
Primary
Concomitant
Sudden Onset Of Sleep Other Serious 62 Female 10/24/2011 Pharmacist Japan
Primary
Concomitant
Cardiac Failure Hospitalization 7/4/2008 58 Female 10/24/2011 Physician Japan
Primary
Concomitant
Sudden Onset Of Sleep Other Serious 62 Female 10/25/2011 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/18/2011 65 Male 106 lb 11/3/2011 Physician Japan
Primary
Concomitant
Sudden Onset Of Sleep Other Serious Female 11/3/2011 Pharmacist Japan
Primary
Concomitant
Diarrhoea Life Threatening 7/15/2009 68 Male 161 lb 11/9/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 6/20/2011 71 Male 11/14/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Triglycerides Increased Hospitalization 10/20/2008 48 Female 11/14/2011 Physician Japan
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 10/3/2011 70 Male 11/16/2011 Physician Japan
Primary
Concomitant
Neutrophil Count Increased Hospitalization 5/3/2010 76 Male 159 lb 11/16/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 6/20/2011 71 Male 11/18/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/8/2011 74 Male 84 lb 11/17/2011 Physician Japan
Primary
Concomitant
Sudden Onset Of Sleep Other Serious Female 11/22/2011 Pharmacist Japan
Primary
Concomitant
Sinusitis Other Serious 71 Male 12/5/2011 Pharmacist France
Primary
Concomitant
Decreased Appetite Hospitalization 10/4/2011 82 Female 71 lb 12/5/2011 Physician Japan
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 5/12/2008 67 Male 121 lb 12/5/2011 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/18/2011 65 Male 106 lb 12/7/2011 Pharmacist Japan
Primary
Concomitant
Skin Ulcer Hospitalization 10/20/2008 48 Female 12/8/2011 Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 5/12/2008 67 Male 121 lb 12/12/2011 Physician Japan
Primary
Concomitant
Intestinal Infarction Death 77 Female 12/12/2011 Physician France
Primary
Secondary
Concomitant
Neoplasm Progression Other Serious 5/1/2011 46 Male 12/13/2011 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 6/10/2011 64 Male 12/15/2011 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 3/10/2011 52 Female 12/15/2011 Physician Japan
Primary
Secondary
Concomitant
Delusion Death 8/26/2010 57 Male 12/13/2011 Physician Japan
Primary
Concomitant
Epilepsy Other Serious 8/26/2011 68 Female 157 lb 12/19/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 6/20/2011 71 Male 12/20/2011 Physician Japan
Primary
Secondary
Concomitant
Localised Infection Other Serious 11/16/2011 49 Female 106 lb 12/19/2011 Physician Japan
Primary
Secondary
Concomitant
Restlessness Hospitalization 10/15/2009 56 Male 12/27/2011 Physician Japan
Primary
Secondary
Concomitant
Bacterial Test Positive Other Serious 5/4/2011 63 Female 87 lb 12/28/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/15/2009 56 Male 1/3/2012 Japan
Primary
Secondary
Concomitant
Cognitive Disorder Other Serious 1/1/2011 94 Female 1/6/2012 Physician France
Primary
Concomitant
Arrhythmia Other Serious 71 Male 1/9/2012 Pharmacist France
Primary
Concomitant
Balance Disorder Hospitalization 10/1/2011 66 Female 1/12/2012 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 10/15/2009 56 Male 1/20/2012 Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 5/16/2011 74 Male 119 lb 1/23/2012 Physician Japan
Primary
Concomitant
Restlessness Hospitalization 10/15/2009 56 Male 1/23/2012 Japan
Primary
Secondary
Concomitant
Influenza Hospitalization 11/7/2010 59 Male 99 lb 1/30/2012 Physician Japan
Primary
Concomitant
Hypoalbuminaemia Hospitalization 7/29/2010 62 Male 126 lb 1/31/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Sodium Increased Other Serious 7/29/2010 62 Male 126 lb 2/7/2012 Physician Japan
Primary
Secondary
Concomitant
Joint Swelling Hospitalization 1/11/2012 66 Female 77 lb 2/13/2012 Physician Japan
Primary
Concomitant
Rectal Ulcer Haemorrhage Hospitalization 10/1/2011 51 Female 2/17/2012 Physician Japan
Primary
Concomitant
Condition Aggravated Hospitalization 1/11/2012 66 Female 77 lb 2/20/2012 Physician Japan
Primary
Concomitant
Depression Death 8/26/2010 57 Male 139 lb 2/13/2012 Physician Japan
Primary
Concomitant
Asthenia Hospitalization 1/17/2012 47 Male 146 lb 2/22/2012 Other Health Professional France
Primary
Secondary
Concomitant
Joint Swelling Hospitalization 1/11/2012 66 Female 77 lb 2/27/2012 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 1/17/2012 47 Male 128 lb 3/1/2012 Other Health Professional France
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 1/1/2010 65 Male 99 lb 3/1/2012 Japan
Primary
Concomitant
Nephrotic Syndrome Other Serious 9/14/2010 42 Female 98 lb 2/28/2012 Physician Japan
Primary
Secondary
Concomitant
Hypoalbuminaemia Other Serious 7/29/2010 62 Male 126 lb 3/7/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Paraesthesia Death 1/17/2012 47 Male 128 lb 3/8/2012 Other Health Professional France
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 11/2/2011 67 Female 117 lb 3/9/2012 Physician Japan
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 1/7/2012 90 Female 3/9/2012 Physician France
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 3/18/2009 62 Male 134 lb 3/16/2012 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 7/20/2011 54 Female 200 lb 3/21/2012 United States
Primary
Secondary
Concomitant
Arrhythmia Hospitalization 1/2/2012 78 Female 115 lb 3/21/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Arrhythmia Hospitalization 1/2/2012 78 Female 114 lb 3/22/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Pneumonia Death 7/20/2011 54 Female 200 lb 3/23/2012 United States
Primary
Secondary
Concomitant
Jaundice Hospitalization 1/16/2012 58 Male 134 lb 3/23/2012 Physician Japan
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Life Threatening 11/30/2011 58 Female 3/26/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Death 8/22/2011 60 Male 119 lb 3/29/2012 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 8/31/2010 66 Male 99 lb 3/29/2012 Japan
Primary
Concomitant
B-cell Lymphoma Stage Iv Disability 7/20/2011 54 Female 174 lb 4/2/2012 United States
Primary
Secondary
Concomitant
Dizziness Other Serious 4/25/2011 71 Male 4/3/2012 Physician Japan
Primary
Secondary
Concomitant
B-cell Lymphoma Stage Iv Life Threatening 7/20/2011 54 Female 186 lb 4/4/2012 United States
Primary
Secondary
Concomitant
Laryngeal Oedema Other Serious Female 152 lb 4/4/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data