Rabeprazole Sodium combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Other Serious 1/1/2006 75 Female 2/6/2006 Japan
Primary
Concomitant
Injection Site Cellulitis Hospitalization 1/10/2006 54 Female 2/24/2006 Ireland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/23/2006 75 Female 3/6/2006 Japan
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 85 Male 3/27/2006 Physician Denmark
Primary
Concomitant
Staphylococcal Sepsis Other Serious 3/15/2006 29 Female 78 lb 4/11/2006 Physician Japan
Primary
Concomitant
Influenza Other Serious 10/24/2005 24 Male 128 lb 4/17/2006 Physician Japan
Primary
Secondary
Concomitant
Haematuria Hospitalization 2/7/2006 66 Female 5/30/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2006 Female 172 lb 6/21/2006 Physician Australia
Primary
Secondary
Concomitant
Lung Neoplasm Hospitalization 3/29/2005 Female 146 lb 7/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Blood Creatine Phosphokinase Increased 5/8/2006 79 Female 7/6/2006 Pharmacist United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 7/10/2006 Male 153 lb 8/8/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/28/2003 56 Male 320 lb 8/21/2006 United States
Primary
Concomitant
Coronary Artery Disease Other Serious 59 Male 167 lb 8/31/2006 United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 7/8/2006 Male 153 lb 9/7/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/8/2006 Male 153 lb 9/8/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Pancytopenia Other Serious 6/8/2006 76 Male 117 lb 9/7/2006 Physician Japan
Primary
Concomitant
Renal Failure Chronic Hospitalization 11/18/2004 51 Female 10/25/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 12/27/2006 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 2/20/2007 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/7/2006 66 Female 5/15/2007 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/7/2006 66 Female 5/29/2007 Physician United Kingdom
Primary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 2/7/2006 66 Female 8/3/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Pyrexia Other Serious 6/1/2007 Female 8/10/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/1/2007 Female 8/15/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/1/2007 Female 9/14/2007 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Life Threatening 8/24/2007 63 Male 115 lb 9/20/2007 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 2 Male 10/9/2007 Physician Saudi Arabia
Primary
Concomitant
Pulmonary Oedema Other Serious 11/1/2007 Male 250 lb 11/21/2007 United States
Primary
Concomitant
Hypoglycaemia Other Serious 5/3/2007 Male 11/30/2007 Consumer United Kingdom
Primary
Concomitant
Renal Failure Hospitalization Male 12/3/2007 Consumer Australia
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/10/2007 Male 123 lb 12/10/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pain 9/1/2007 Female 130 lb 12/14/2007 United States
Primary
Concomitant
Completed Suicide Other Serious 1/10/2005 Female 176 lb 12/18/2007 Physician Japan
Primary
Concomitant
Hypertension Other Serious 3/22/2005 86 Female 12/14/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Meningitis Hospitalization 6/27/2007 Female 110 lb 2/15/2008 Physician Japan
Primary
Concomitant
Renal Disorder Life Threatening 12/18/2007 70 Male 132 lb 2/20/2008 Physician Japan
Primary
Secondary
Concomitant
Meningitis Hospitalization 6/27/2007 Female 110 lb 2/21/2008 Physician Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 12/13/2007 Female 93 lb 3/14/2008 Physician Japan
Primary
Secondary
Cerebral Haemorrhage Death 2/12/2008 81 Male 119 lb 3/18/2008 Physician Japan
Primary
Concomitant
Varicella Life Threatening 5/13/2007 18 Female 110 lb 4/28/2008 Physician Japan
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Other Serious 3/12/2008 81 Female 5/29/2008 United Kingdom
Primary
Secondary
Concomitant
Protein Total Decreased Hospitalization 12/12/2007 83 Female 88 lb 6/9/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/28/2003 Male 320 lb 6/19/2008 Lawyer United States
Primary
Concomitant
Jaundice Other Serious 5/14/2008 Male 144 lb 6/30/2008 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 6/9/2008 52 Male 154 lb 7/28/2008 Physician Japan
Primary
Concomitant
Pulmonary Embolism Other Serious 5/31/2008 66 Male 8/7/2008 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/10/2007 Male 123 lb 8/18/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 5/1/2008 82 Female 8/21/2008 Consumer Canada
Primary
Concomitant
Insomnia Hospitalization 6/5/2008 59 Male 146 lb 8/20/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 74 Female 8/27/2008 United States
Primary
Concomitant
Pain Of Skin 8/16/2007 Female 185 lb 8/27/2008 Consumer United States
Primary
Concomitant
Melaena Other Serious 8/18/2008 71 Male 8/29/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 69 Male 161 lb 9/8/2008 Physician Japan
Primary
Concomitant
Neoplasm Malignant Hospitalization 5/13/2008 Male 9/8/2008 Canada
Primary
Concomitant
Liver Disorder Hospitalization 6/2/2008 63 Male 9/10/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 11/18/2004 51 Female 9/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Occlusion Hospitalization 7/1/2008 Female 212 lb 9/18/2008 United States
Primary
Concomitant
Respiratory Tract Haemorrhage Other Serious 8/18/2008 71 Male 9/19/2008 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Hospitalization 11/16/2007 62 Male 143 lb 9/22/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 5/10/2007 Male 123 lb 9/23/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 8/3/2008 84 Male 134 lb 9/30/2008 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 8/3/2008 84 Male 134 lb 10/1/2008 Physician Japan
Primary
Concomitant
Respiratory Tract Haemorrhage Other Serious 8/18/2008 71 Male 10/6/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/3/2008 84 Male 134 lb 10/22/2008 Physician Japan
Primary
Concomitant
Throat Irritation Other Serious 8/20/2007 63 Female 9/18/2008 United States
Primary
Concomitant
Haemorrhage Life Threatening 10/30/2007 Male 157 lb 11/3/2008 Physician Canada
Primary
Concomitant
Interstitial Lung Disease Death 1/21/2008 69 Male 161 lb 11/4/2008 Physician Japan
Primary
Concomitant
Somnolence Other Serious 9/6/2008 Female 11/7/2008 Physician Japan
Primary
Concomitant
Interacting
Somnolence Other Serious 8/29/2008 Female 11/19/2008 Physician Japan
Primary
Concomitant
Interacting
Cardiac Failure Hospitalization 74 Female 11/21/2008 Italy
Primary
Concomitant
Thrombocytopenia Hospitalization 9/12/2008 Male 115 lb 11/26/2008 Physician Japan
Primary
Secondary
Concomitant
Muscle Spasms 9/23/2008 Female 130 lb 11/26/2008
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/19/2008 67 Female 12/1/2008 Other Health Professional Japan
Primary
Concomitant
Pain In Extremity Female 12/12/2008 United States
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/19/2008 68 Female 104 lb 12/15/2008 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/26/2007 65 Male 161 lb 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 5/10/2007 Male 123 lb 12/23/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/12/2008 1/5/2009 Japan
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 8/6/2008 60 Female 90 lb 2/9/2009 Other Health Professional Japan
Primary
Concomitant
Platelet Count Decreased Death 4/14/2008 72 Male 2/9/2009 Japan
Primary
Concomitant
Cardiac Failure Other Serious 74 Female 3/9/2009 Physician United States
Primary
Concomitant
Hyponatraemia Other Serious 77 Female 4/13/2009 Canada
Primary
Concomitant
Cardiac Failure Hospitalization 74 Female 4/20/2009 Other Health Professional Italy
Primary
Concomitant
Hypotension Life Threatening 3/16/2009 78 Male 5/4/2009 United Kingdom
Primary
Concomitant
Thyroidectomy Other Serious 1/1/2000 Male 190 lb 5/15/2009 Consumer United States
Primary
Concomitant
Interacting
Haemoptysis Other Serious 3/28/2009 64 5/21/2009 Pharmacist Canada
Primary
Concomitant
Varicella Life Threatening 5/13/2007 18 Female 110 lb 6/8/2009 Physician Japan
Primary
Secondary
Concomitant
Stent Occlusion Other Serious 6/20/2008 Male 189 lb 6/25/2009 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Life Threatening 5/11/2009 Male 203 lb 7/15/2009 Canada
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 6/18/2009 83 Male 7/30/2009 Consumer United States
Primary
Secondary
Concomitant
Injection Site Pain 6/21/2007 Female 280 lb 9/11/2009 United States
Primary
Concomitant
Vomiting Other Serious 9/1/2007 49 Female 99 lb 10/6/2009 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Death 5/2/2008 72 Male 10/14/2009 Japan
Primary
Concomitant
Corneal Erosion Disability 9/25/2009 57 Male 11/4/2009 Physician Japan
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 1/8/2009 62 Female 117 lb 11/13/2009 Physician Japan
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 1/8/2009 62 117 lb 12/2/2009 Physician Japan
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Other Serious 7/1/2009 81 Female 12/5/2009 United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization 1/8/2009 62 Female 117 lb 1/29/2010 Physician Japan
Primary
Secondary
Concomitant
Tremor Other Serious 9/1/2003 73 Female 2/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Life Threatening 5/1/2008 82 Female 2/23/2010 Other Health Professional Canada
Primary
Concomitant
Drug Interaction Hospitalization 1/8/2009 62 Female 117 lb 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 3/19/2010 Male 211 lb 3/25/2010 Canada
Primary
Secondary
Concomitant
Small Intestinal Perforation Other Serious 70 Female 3/30/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 70 Female 3/31/2010 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2010 38 Female 126 lb 4/26/2010 Physician Canada
Primary
Concomitant
Tremor Other Serious 9/1/2007 49 Female 99 lb 4/26/2010 Physician Japan
Primary
Secondary
Concomitant
Urticaria Other Serious 5/26/2010 72 Female 119 lb 6/4/2010 Other Health Professional Canada
Primary
Concomitant
Melaena Death 2/16/2008 84 Female 7/15/2010 Japan
Primary
Secondary
Concomitant
Testis Cancer Hospitalization 11/26/2009 72 Male 132 lb 7/19/2010 Physician Japan
Primary
Concomitant
Cardiac Disorder Hospitalization 57 Male 8/2/2010 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/2/2010 58 Female 194 lb 7/1/2010 Pharmacist United States
Primary
Concomitant
Testis Cancer Hospitalization 11/26/2009 72 Male 132 lb 8/20/2010 Physician Japan
Primary
Concomitant
Muscle Haemorrhage Hospitalization 6/30/2010 64 Male 8/30/2010 Physician Japan
Primary
Secondary
Concomitant
Retinal Detachment Hospitalization 8/3/2010 75 Male 9/8/2010 Physician Switzerland
Primary
Concomitant
Renal Function Test Abnormal Other Serious 1/25/2010 38 Female 9/15/2010 Physician Canada
Primary
Concomitant
Renal Function Test Abnormal Other Serious 1/25/2010 38 Female 10/22/2010 Physician Canada
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 10/8/2008 20 Female 133 lb 10/28/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Ischaemia Hospitalization 1/1/2007 68 Male 3/3/2011 Physician United States
Primary
Concomitant
Coordination Abnormal Life Threatening 91 Female 5/12/2011 Physician Canada
Primary
Concomitant
Muscle Contracture Life Threatening 91 Female 5/12/2011 Physician Canada
Primary
Concomitant
Muscle Spasms Other Serious 4/1/2011 70 Female 5/13/2011 Consumer Canada
Primary
Concomitant
Renal Impairment Hospitalization 4/14/2011 47 Male 5/20/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Hyperkalaemia Hospitalization 7/1/2010 81 Female 88 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization 3/8/2011 31 Male 5/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Death 3/30/2011 73 Male 120 lb 6/1/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 3/8/2011 77 Female 6/3/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Haematochezia Other Serious 4/25/2011 75 Male 6/6/2011 Physician Japan
Primary
Concomitant
Deep Vein Thrombosis Life Threatening 3/31/2011 67 Female 176 lb 6/7/2011 Physician Australia
Primary
Concomitant
Hypothyroidism Other Serious 1/11/2011 68 Male 6/10/2011 Consumer Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 4/27/2010 79 Female 6/13/2011 Other Health Professional Japan
Primary
Concomitant
Platelet Count Decreased Life Threatening 12/2/2010 58 Female 82 lb 6/13/2011 Physician Japan
Primary
Concomitant
Epistaxis Hospitalization 1/22/2003 66 Male 134 lb 6/11/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Death 3/30/2011 73 Male 120 lb 6/14/2011 Physician Japan
Primary
Secondary
Concomitant
Intentional Drug Misuse 3/1/2011 70 Female 6/17/2011 Consumer Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/10/2011 76 Male 6/21/2011 Physician Canada
Primary
Concomitant
Epilepsy Hospitalization 6/1/2011 83 Male 141 lb 6/27/2011 Physician Japan
Primary
Secondary
Blood Urea Increased Other Serious Male 6/28/2011 Consumer Korea, Republic Of
Primary
Concomitant
Retinal Detachment Disability 8/3/2009 74 Male 7/7/2011 Consumer Switzerland
Primary
Concomitant
Cardiac Failure Congestive Other Serious 8/7/2009 64 Male 138 lb 7/7/2011 Physician Japan
Primary
Concomitant
Epilepsy Hospitalization 6/1/2011 83 Male 141 lb 7/11/2011 Physician Japan
Primary
Secondary
Constipation Other Serious 3/10/2011 75 Male 7/12/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 4/16/2011 59 Female 7/13/2011 Physician United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 4/27/2010 79 Female 7/22/2011 Other Health Professional Japan
Primary
Concomitant
Vulval Cellulitis Hospitalization 6/28/2011 63 Female 260 lb 7/26/2011 Physician Australia
Primary
Secondary
Concomitant
International Normalised Ratio Increased Disability 7/10/2011 88 Female 93 lb 7/27/2011 Physician Japan
Primary
Concomitant
Interacting
Vulval Cellulitis Hospitalization 6/22/2011 63 Female 260 lb 8/2/2011 Physician Australia
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 7/10/2011 88 Female 93 lb 8/2/2011 Physician Japan
Primary
Concomitant
Interacting
Unevaluable Event Death 7/6/2007 75 Male 146 lb 8/2/2011 Consumer United States
Primary
Concomitant

Drug Data