Quetiapine combined with Valproic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Completed Suicide Death 16 3/9/2006 United States
Primary
Secondary
Unresponsive To Pain Stimuli Other Serious 45 Male 3/9/2006 United States
Primary
Secondary
Suicide Attempt Other Serious 41 Male 4/3/2006 Physician United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/13/2006 48 Female 203 lb 5/18/2006 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 8/9/2006 54 Female 170 lb 9/7/2006 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 26 Female 9/15/2006 Physician United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 4/26/2006 Female 9/15/2006 United Kingdom
Primary
Secondary
Concomitant
Haematemesis Hospitalization 7/25/2006 Male 9/20/2006 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 26 11/9/2006 United States
Primary
Secondary
Respiratory Arrest Death 50 11/10/2006 United States
Primary
Secondary
Completed Suicide Death 50 11/10/2006 United States
Primary
Secondary
Urine Cannabinoids Increased Hospitalization 57 Male 5/23/2007 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 25 Male 6/15/2007 United States
Primary
Concomitant
Pleural Effusion Other Serious 25 Male 6/26/2007 United States
Primary
Concomitant
Liver Function Test Abnormal 3/10/2006 70 Male 150 lb 3/15/2006 Pharmacist United States
Primary
Secondary
Pleurothotonus Other Serious 39 Female 1/7/2008 France
Primary
Secondary
Interacting
Tremor Other Serious 6/18/2008 20 Female 8/18/2008 Other Health Professional Australia
Primary
Concomitant
Completed Suicide Death 1/1/2007 36 Male 12/24/2008 Physician United States
Primary
Secondary
Death Death 21 Female 12/24/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 36 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 29 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 48 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 18 Female 12/31/2008 Pharmacist United States
Primary
Secondary
Drug Interaction Other Serious 54 Male 12/31/2008 Other Health Professional Canada
Primary
Secondary
Interacting
Death Death 20 Male 12/31/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 40 Male 12/31/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 18 Female 1/30/2009 Other Health Professional United States
Primary
Secondary
Suicidal Ideation Hospitalization 1/23/2009 Female 216 lb 4/8/2009 Physician Austria
Primary
Concomitant
Urinary Incontinence Other Serious 12/15/2008 Female 4/13/2009 Physician Canada
Primary
Concomitant
Completed Suicide Death 1/1/2007 18 Female 5/7/2009 Physician United States
Primary
Secondary
Pneumonia Other Serious 26 Female 5/13/2009 Physician United States
Primary
Secondary
Concomitant
Myopathy Other Serious 85 Female 8/20/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Psychotic Disorder Other Serious 42 Female 8/28/2009
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 10/1/2008 40 Male 9/4/2009 Physician United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 47 Female 9/16/2009 Other Health Professional Spain
Primary
Concomitant
Multiple Drug Overdose Intentional Hospitalization 34 Female 9/25/2009 Other Health Professional United States
Primary
Secondary
Multiple Drug Overdose Intentional Hospitalization 34 Female 10/9/2009 Physician United States
Primary
Secondary
Neutropenia Other Serious 5/22/2009 86 Female 10/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Judgement Impaired Other Serious 26 Male 192 lb 11/8/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/21/2009 55 Female 11/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Oedema Peripheral Other Serious 44 Male 11/24/2009
Primary
Secondary
Concomitant
Metabolic Syndrome Hospitalization 28 Female 12/1/2009 Other Health Professional Turkey
Primary
Secondary
Drug Ineffective 63 Female 1/25/2010 Physician United States
Primary
Secondary
Sedation Other Serious 48 Female 1/28/2010 Other Health Professional United States
Primary
Secondary
Interacting
Tremor Other Serious 10/1/2002 48 Male 1/29/2010
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 58 Male 2/5/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 12/22/2009 64 Female 2/18/2010 Pharmacist United States
Primary
Concomitant
Drug Toxicity Death 4/10/2008 40 Female 225 lb 3/11/2010 Consumer United States
Primary
Secondary
Sedation Hospitalization 38 Female 4/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Female 6/24/2010 Physician United States
Primary
Secondary
Treatment Noncompliance Hospitalization 30 6/25/2010 Other Health Professional Germany
Primary
Concomitant
Sick Sinus Syndrome Other Serious 51 Male 8/24/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Treatment Noncompliance Hospitalization 30 8/26/2010 Other Health Professional Germany
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 31 Female 9/10/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 9/10/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Drug Interaction Other Serious 53 Female 9/13/2010 Physician Taiwan, Province Of China
Primary
Interacting
Drug Interaction Other Serious 63 Male 9/13/2010 Physician Taiwan, Province Of China
Primary
Interacting
Hepatic Enzyme Increased Hospitalization 26 Male 9/20/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Hospitalization 26 Male 9/21/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Osteoporosis Other Serious 29 Male 9/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Sick Sinus Syndrome Other Serious 51 Male 10/4/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Unresponsive To Stimuli Death 3/9/2010 14 Male 10/27/2010 Physician United States
Primary
Secondary
Off Label Use Death 3/9/2010 14 Male 10/28/2010 Physician United States
Primary
Secondary
Salivary Hypersecretion Other Serious 10/1/2010 9 Male 11/1/2010 Consumer Canada
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 16 Female 11/22/2010 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 10/1/2010 9 Male 11/22/2010 Consumer Canada
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/4/2007 16 Female 12/21/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization Male 12/28/2010 Other Health Professional Canada
Primary
Concomitant
Completed Suicide Death 54 Male 1/4/2011 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 10 Male 1/4/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 38 Male 1/4/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 36 Female 1/4/2011 Other Health Professional United States
Primary
Secondary
Dysarthria Other Serious 10/1/2010 9 Male 1/5/2011 Consumer Argentina
Primary
Secondary
Concomitant
Completed Suicide Death 76 Female 1/5/2011 Other Health Professional United States
Primary
Secondary
Injury Death 1/1/2009 10 Male 1/6/2011 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process Death 10 Male 1/10/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 1/1/2009 36 Female 1/7/2011 Physician United States
Primary
Secondary
Completed Suicide Death 38 Male 1/11/2011 Other Health Professional United States
Primary
Secondary
Intentional Drug Misuse Hospitalization 10 Male 1/12/2011 Physician United States
Primary
Secondary
Death Death 38 Male 1/13/2011 Physician United States
Primary
Secondary
Drug Interaction Hospitalization 8/1/2007 66 Female 115 lb 1/13/2011 Physician Spain
Primary
Concomitant
Interacting
Death Death 76 Female 1/19/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 36 Female 1/20/2011 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 76 Female 1/21/2011 Physician United States
Primary
Secondary
Completed Suicide Death 54 Male 1/21/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 36 Female 1/21/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 10 Male 1/21/2011 Physician United States
Primary
Secondary
Completed Suicide Death 38 Male 1/21/2011 Physician United States
Primary
Secondary
Paranoia Other Serious 9/4/2007 16 Female 1/21/2011 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 38 Male 1/25/2011 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Other Serious 10 Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 38 Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 1/1/2009 10 Male 1/26/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 1/1/2009 10 Male 1/26/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 36 Female 1/20/2011 United States
Primary
Secondary
Cardiac Arrest Death 10 Male 1/20/2011 United States
Primary
Secondary
Vision Blurred Hospitalization 11/2/2010 25 Male 2/9/2011 Physician Germany
Primary
Concomitant
Respiratory Arrest Death 1/1/2009 10 Male 1/26/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2009 38 Male 1/28/2011 Physician United States
Primary
Secondary
Completed Suicide Death 38 Male 2/2/2011 United States
Primary
Secondary
Blood Creatine Phosphokinase Increased Hospitalization 26 Male 2/21/2011 Other Health Professional Turkey
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/20/2011 46 Female 159 lb 2/11/2011 Consumer Brazil
Primary
Concomitant
Completed Suicide Death 38 Male 3/7/2011 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 10 Male 3/7/2011 Other Health Professional United States
Primary
Secondary
Death Death 10 Male 2/25/2011 Physician United States
Primary
Concomitant
Completed Suicide Death 38 Male 3/9/2011 Physician United States
Primary
Secondary
Child Abuse Death 10 Male 3/14/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 10 Male 3/24/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 76 Female 3/24/2011 Physician United States
Primary
Secondary
Mania Hospitalization 1/31/2011 72 Female 4/6/2011 Physician Austria
Primary
Concomitant
Completed Suicide Death 38 Male 3/30/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 10 Male 3/30/2011 Other Health Professional United States
Primary
Secondary
Drug Interaction Hospitalization 44 Male 4/25/2011 Physician Taiwan, Province Of China
Primary
Concomitant
Interacting
Mania Hospitalization 1/31/2011 72 Female 4/27/2011 Consumer Austria
Primary
Concomitant
Granulocytopenia Hospitalization 1/20/2011 30 Female 5/24/2011 Physician Finland
Primary
Secondary
Concomitant
Cognitive Disorder Hospitalization 8/1/2007 66 Female 115 lb 5/27/2011 Physician Spain
Primary
Concomitant
Interacting
Cognitive Disorder Hospitalization 3/1/2007 66 Female 6/3/2011 Physician Spain
Primary
Concomitant
Interacting
Compulsions Other Serious 33 Male 5/27/2011 Other Health Professional Germany
Primary
Concomitant
Cognitive Disorder Disability 8/1/2007 66 Female 6/28/2011 Physician Spain
Primary
Interacting
Infection Hospitalization 4/19/2011 53 Female 7/1/2011 Pharmacist Ireland
Primary
Concomitant
Hypothyroidism Other Serious 29 Female 7/6/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Interacting
Thyroid Function Test Abnormal Other Serious 21 Female 7/7/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Interacting
Tremor Other Serious 66 Female 7/7/2011 Other Health Professional Spain
Primary
Concomitant
Interacting
Dysphagia Other Serious 1/1/2010 85 Male 7/12/2011 Physician Japan
Primary
Secondary
Convulsion Hospitalization 6/28/2011 46 Female 177 lb 7/14/2011 Consumer United States
Primary
Concomitant
Drug Intolerance Other Serious 61 Female 8/22/2011 Other Health Professional United States
Primary
Secondary
Type 2 Diabetes Mellitus 3/29/2005 38 Female 8/26/2011 Physician Canada
Primary
Concomitant
Metastases To Central Nervous System Hospitalization 6/18/2011 58 Female 9/7/2011 Physician Ireland
Primary
Concomitant
Hyperglycaemia Other Serious 12/9/2006 64 Male 9/12/2011 Consumer Canada
Primary
Secondary
Concomitant
Completed Suicide Death 9/23/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 38 9/23/2011 Other Health Professional United States
Primary
Secondary
Overdose Hospitalization Male 9/22/2011 Consumer Canada
Primary
Concomitant
Metastases To Central Nervous System Hospitalization 6/18/2011 58 Female 10/19/2011 Other Health Professional Ireland
Primary
Concomitant
Hyperprolactinaemia Other Serious Male 10/20/2011 Pharmacist United States
Primary
Secondary
Concomitant
Liver Injury Other Serious 37 Male 10/26/2011 Physician Korea, Republic Of
Primary
Concomitant
Diabetic Ketoacidosis Life Threatening 39 Male 10/31/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Life Threatening 39 Male 11/10/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Swelling Face 1/20/2011 46 Female 159 lb 11/7/2011 Consumer Brazil
Primary
Concomitant
Hyponatraemia Hospitalization Male 11/30/2011 Other Health Professional Slovakia (Slovak Republic)
Primary
Concomitant
Suicidal Ideation Other Serious 76 Female 12/14/2011 Other Health Professional United States
Primary
Secondary
Suicidal Ideation Other Serious 76 Female 12/14/2011 Other Health Professional United States
Primary
Secondary
Electrocardiogram Qt Prolonged Other Serious 56 Male 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 56 Male 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 10 Male 12/15/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 10 Male 12/15/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 10 Male 12/15/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 45 Male 12/20/2011 Physician United States
Primary
Secondary
Completed Suicide Death 36 Female 12/20/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 14 Male 12/20/2011 Physician United States
Primary
Secondary
Completed Suicide Death 29 Female 12/21/2011 Physician United States
Primary
Secondary

Drug Data