Quetiapine combined with Valproate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Hospitalization 1/30/2006 65 Female 10/17/2006 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/1999 31 Female 156 lb 4/2/2007 Consumer United States
Primary
Concomitant
Neutropenia Female 6/20/2007 Physician United Kingdom
Primary
Concomitant
Tardive Dyskinesia Disability 8/1/2006 58 Male 6/22/2007 United Kingdom
Primary
Concomitant
Tongue Paralysis Disability 8/1/2006 58 Male 6/29/2007 United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 45 Male 12/18/2007 Physician India
Primary
Concomitant
Sedation Hospitalization 4/1/2007 33 Male 12/20/2007 Physician Germany
Primary
Concomitant
Interacting
Muscle Spasms 12/6/2007 Female 150 lb 3/14/2008 United States
Primary
Concomitant
Tachycardia Hospitalization 36 Female 3/19/2008 Other Health Professional France
Primary
Secondary
Concomitant
Generalised Anxiety Disorder Other Serious 6/7/2008 31 Female 122 lb 9/5/2008 Physician United Kingdom
Primary
Secondary
Generalised Anxiety Disorder Death 6/7/2008 31 Female 122 lb 9/11/2008 Physician United Kingdom
Primary
Secondary
Weight Decreased 6/1/2008 Male 193 lb 9/13/2008 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 3/20/2008 Male 183 lb 9/16/2008 Physician Germany
Primary
Concomitant
Cough Death 9/4/2008 48 Female 9/19/2008 Physician Uruguay
Primary
Concomitant
Sudden Cardiac Death Death 6/7/2008 31 Female 9/19/2008 Other Health Professional France
Primary
Secondary
Paranoia Other Serious 1/1/2007 2/11/2009 Other Health Professional Slovenia
Primary
Concomitant
Hypotension 3/4/2009 Other Health Professional United States
Primary
Concomitant
Tremor Female 3/4/2009 Consumer United States
Primary
Concomitant
Drug Toxicity Death 42 Male 3/26/2009 United States
Primary
Secondary
Drug Toxicity Death 42 Male 4/6/2009 Denmark
Primary
Secondary
Vomiting Other Serious 4/1/2009 Female 5/4/2009 Other Health Professional United States
Primary
Secondary
Metabolic Syndrome Other Serious 10/1/2008 40 Male 8/18/2009 Consumer Germany
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Other Serious 11/1/2008 Female 8/27/2009 Physician United Kingdom
Primary
Concomitant
Vascular Pseudoaneurysm Other Serious 11/1/2008 Female 9/2/2009 Physician United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 53 Female 9/3/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Drug Interaction Other Serious 63 Male 9/3/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/4/2009 Physician United Kingdom
Primary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/9/2009 Physician France
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 11/17/2003 48 Female 10/16/2009 Physician New Zealand
Primary
Concomitant
Vomiting Other Serious 10/27/2009 Other Health Professional Turkey
Primary
Secondary
Somnolence Other Serious 3/1/2007 42 Male 11/5/2009 Physician India
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/21/2009 55 Female 11/20/2009 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 10/21/2009 55 Female 12/14/2009 Physician United Kingdom
Primary
Secondary
Parkinsonism Other Serious 78 Male 12/16/2009 Physician United States
Primary
Concomitant
Leukopenia Other Serious 8/1/2005 59 Female 2/1/2010 Physician United Kingdom
Primary
Concomitant
Delirium Other Serious 46 Female 3/24/2010 Turkey
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/21/2009 55 Female 4/19/2010 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 10/21/2009 55 Female 4/22/2010 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/1/2008 40 Male 5/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 5/24/2010 France
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/1/2008 40 Male 5/20/2010 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/1/2008 40 Male 231 lb 5/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dystonia Hospitalization 31 Female 6/21/2010 Other Health Professional Poland
Primary
Concomitant
Hypertension Hospitalization 31 Female 7/1/2010 Other Health Professional Poland
Primary
Concomitant
Social Avoidant Behaviour Required Intervention 6/6/2009 46 Female 126 lb 7/20/2010 Consumer United States
Primary
Secondary
Concomitant
Sexual Dysfunction Hospitalization 1/1/2006 36 Male 8/9/2010 Physician Korea, Republic Of
Primary
Secondary
Drug Interaction Other Serious 63 Male 8/20/2010 Other Health Professional China
Primary
Secondary
Drug Interaction Other Serious 53 Female 8/23/2010 Other Health Professional China
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization Female 123 lb 8/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 7/1/2010 43 Male 8/26/2010 Pharmacist Australia
Primary
Concomitant
Psychotic Disorder Other Serious 11/1/2009 44 Female 8/26/2010 Physician Portugal
Primary
Secondary
Concomitant
Swelling Face Other Serious 8/8/2010 16 Female 9/1/2010 Physician Finland
Primary
Concomitant
Psychotic Disorder Other Serious 11/1/2009 44 Female 9/10/2010 Physician Portugal
Primary
Secondary
Concomitant
Tachycardia Hospitalization 55 Male 9/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ulcer Hospitalization 28 Male 9/22/2010 Consumer Poland
Primary
Concomitant
Osteoporosis Other Serious 29 Male 10/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Neutropenia Other Serious 12/29/2010 25 Male 2/2/2011 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/29/2010 25 Male 2/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Antipsychotic Drug Level Increased Other Serious Female 2/23/2011 India
Primary
Secondary
Concomitant
Myoclonus Other Serious 1/1/2009 34 Male 191 lb 3/10/2011 Physician Ireland
Primary
Secondary
Concomitant
Bipolar Disorder Other Serious 62 Female 3/10/2011 Physician India
Primary
Secondary
Transient Ischaemic Attack Hospitalization 3/29/2011 49 Female 5/9/2011 Physician United Kingdom
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 4/1/2010 66 Female 117 lb 6/2/2011 Physician United Kingdom
Primary
Concomitant
Cognitive Disorder Hospitalization 8/1/2007 66 Female 6/3/2011 Physician Spain
Primary
Secondary
Overdose Death 25 Male 6/6/2011 Physician Australia
Primary
Secondary
Concomitant
Leukopenia Other Serious 9/13/2010 46 Male 6/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
Eating Disorder Hospitalization 85 Male 7/1/2011 Other Health Professional Japan
Primary
Secondary
Cerebral Atrophy Hospitalization 66 Male 7/7/2011 Physician Greece
Primary
Secondary
Antipsychotic Drug Level Above Therapeutic Other Serious 1/1/2005 53 Male 7/28/2011 New Zealand
Primary
Concomitant
Dilatation Ventricular Hospitalization 1/1/2009 20 Female 8/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Heart Rate Increased Hospitalization 1/1/2009 20 Female 8/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 4 Female 8/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 4 Female 8/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 3/29/2011 49 Female 8/26/2011 Physician United Kingdom
Primary
Concomitant
Death Death 4 Female 9/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 4 Female 9/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 4 Female 9/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 1/1/2009 34 Male 191 lb 9/8/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 3/29/2011 49 Female 9/12/2011 Physician United Kingdom
Primary
Concomitant
Dystonia Other Serious 1/1/2009 34 Male 191 lb 9/13/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 1/1/2009 20 Female 9/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 3/24/2003 50 Female 9/14/2011 Consumer Canada
Primary
Concomitant
Dysphoria Other Serious 48 Male 9/19/2011 Physician Hungary
Primary
Concomitant
Mean Cell Haemoglobin Concentration Other Serious 1/1/2009 34 Male 191 lb 9/23/2011 Physician Ireland
Primary
Secondary
Concomitant
Heart Rate Increased Hospitalization 1/1/2009 20 Female 9/23/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Dyslipidaemia Other Serious 56 Male 9/29/2011 Other Health Professional Romania
Primary
Secondary
Dyslipidaemia Other Serious 40 Male 9/29/2011 Other Health Professional Romania
Primary
Secondary
Blood Triglycerides Increased Other Serious 40 Male 9/29/2011 Other Health Professional Romania
Primary
Secondary
Blood Triglycerides Increased Other Serious 40 Male 9/29/2011 Other Health Professional Romania
Primary
Secondary
Completed Suicide Death 2/13/2011 69 Male 10/4/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Pulmonary Oedema Death 9/11/2011 48 Female 10/12/2011 Other Health Professional New Zealand
Primary
Concomitant
Blood Triglycerides Increased Other Serious 54 Male 10/18/2011 Other Health Professional Romania
Primary
Secondary
Blood Triglycerides Increased Other Serious 56 Male 10/18/2011 Other Health Professional Romania
Primary
Secondary
Blood Triglycerides Increased Other Serious 40 Male 10/18/2011 Other Health Professional Romania
Primary
Secondary
Drug Ineffective Other Serious 1/1/2009 34 Male 191 lb 10/20/2011 Physician Ireland
Primary
Secondary
Concomitant
Alcohol Use Death 2/13/2011 69 Male 10/20/2011 Physician Switzerland
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 39 Male 11/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stridor Other Serious 11/1/2008 38 Female 11/11/2011 Physician United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 45 Female 11/14/2011 Other Health Professional United Kingdom
Primary
Concomitant
Foetal Growth Restriction Death 11/21/2011 Physician Germany
Primary
Secondary
Feeling Abnormal Hospitalization 7/1/2011 30 Female 11/29/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Gestational Diabetes Other Serious Female 209 lb 11/29/2011 Consumer Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/4/2011 36 Female 12/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 37 Male 12/14/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 37 Male 12/20/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Mental Impairment Other Serious 2/1/2007 54 Male 12/23/2011 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Suicidal Ideation Hospitalization 2/1/2007 54 Male 12/23/2011 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Apathy Other Serious 55 Female 1/13/2012 Physician Hungary
Primary
Concomitant
Hip Arthroplasty Hospitalization 12/21/2011 45 Female 150 lb 1/26/2012 Other Health Professional Canada
Primary
Concomitant
Toxic Skin Eruption Hospitalization 27 Female 1/31/2012 Physician United States
Primary
Secondary
Death Death 10/10/2011 88 Male 2/1/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Off Label Use 1/16/2012 61 Male 163 lb 1/30/2012 Physician Israel
Primary
Concomitant
Psychotic Disorder Other Serious 5/1/2011 45 Female 2/14/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Salmonellosis Hospitalization Male 2/15/2012 Pharmacist Australia
Primary
Concomitant
Mental Impairment Hospitalization 6/23/2009 24 Male 2/20/2012 Pharmacist Australia
Primary
Concomitant
Headache Hospitalization 36 Female 2/23/2012 Other Health Professional Australia
Primary
Concomitant
Headache Hospitalization 36 Female 2/24/2012 Other Health Professional Australia
Primary
Concomitant
Pleurothotonus Other Serious 47 Female 2/24/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Delirium Other Serious 40 Male 2/28/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Hypoacusis Hospitalization 67 Female 3/1/2012 Other Health Professional Germany
Primary
Concomitant
Convulsion Hospitalization 60 Female 106 lb 3/2/2012 Physician Canada
Primary
Secondary
Concomitant
Mania 32 Female 3/1/2012 Physician Italy
Primary
Concomitant
Suicide Attempt Life Threatening 11/1/2010 31 Male 3/13/2012 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Death 2/17/2012 51 Female 3/15/2012 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/4/2011 36 Female 3/23/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thought Blocking 32 Female 3/20/2012 Physician Italy
Primary
Concomitant
Neurotoxicity Required Intervention 27 Male 4/6/2012 Physician Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 2/28/2012 43 Male 4/12/2012 Pharmacist Australia
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 8/1/2011 40 Male 265 lb 4/16/2012 Physician Australia
Primary
Concomitant
Intestinal Dilatation Other Serious 7/7/2010 36 Female 4/26/2012 Other Health Professional Australia
Primary
Concomitant
C-reactive Protein Increased Life Threatening 6/11/2010 36 Female 4/26/2012 Other Health Professional Australia
Primary
Concomitant
Pyrexia Hospitalization 7/7/2010 36 Female 5/3/2012 Other Health Professional Australia
Primary
Concomitant
Full Blood Count Abnormal Hospitalization 11/1/2010 31 Male 5/21/2012 Physician United Kingdom
Primary
Concomitant
Pleurothotonus Death 47 Female 5/28/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Multi-organ Failure Death Female 6/4/2012 Other Health Professional Canada
Primary
Concomitant
Delirium Life Threatening 34 Male 6/19/2012 Physician Japan
Primary
Concomitant
Multi-organ Failure Death Female 6/20/2012 Physician Canada
Primary
Concomitant
Pyrexia Hospitalization 60 Female 172 lb 6/26/2012 Physician Canada
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 1/1/2009 34 Male 191 lb 6/28/2012 Other Health Professional Ireland
Primary
Secondary
Concomitant
Aggression Life Threatening 11/1/2010 31 Male 6/29/2012 Physician United Kingdom
Primary
Concomitant
Drug Ineffective Death 43 Male 6/29/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 40 Female 7/2/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperammonaemia Other Serious 37 Female 7/5/2012 Other Health Professional Portugal
Primary
Secondary
Concomitant
Agitation Life Threatening 34 Male 7/3/2012 Physician Japan
Primary
Concomitant
Overdose Other Serious 22 Male 7/16/2012 Other Health Professional Hong Kong
Primary
Secondary
Platelet Count Decreased Other Serious 8/10/2010 36 Male 191 lb 7/30/2012 Other Health Professional Ireland
Primary
Secondary
Concomitant
Neutropenia Hospitalization 85 Male 7/30/2012 Physician Taiwan, Province Of China
Primary
Interacting

Drug Data