Pydoxal combined with Xeloda

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Metastasis Other Serious 9/3/2006 69 Female 126 lb 11/6/2006 Physician Japan
Primary
Concomitant
Epilepsy Other Serious 9/6/2006 69 Female 126 lb 2/5/2007 Physician Japan
Primary
Concomitant
Epilepsy Other Serious 9/6/2006 69 Female 126 lb 2/5/2007 Physician Japan
Primary
Concomitant
Epilepsy Other Serious 9/6/2006 69 Female 126 lb 6/13/2007 Physician Japan
Primary
Concomitant
Visual Acuity Reduced Disability 7/1/2007 68 Female 104 lb 9/28/2007 Physician Japan
Primary
Concomitant
Visual Acuity Reduced Hospitalization 7/20/2007 68 Female 104 lb 11/2/2007 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 9/6/2006 69 Female 126 lb 12/19/2007 Physician Japan
Primary
Concomitant
Intestinal Ischaemia Death 1/11/2008 Female 117 lb 5/12/2008 Physician Japan
Primary
Concomitant
Intestinal Ischaemia Death 1/11/2008 Female 117 lb 5/29/2008 Physician Japan
Primary
Concomitant
Retinal Tear Other Serious 3/5/2008 Female 128 lb 6/25/2008 Physician Japan
Primary
Concomitant
Rectal Ulcer Life Threatening 6/24/2008 71 Female 132 lb 7/15/2008 Physician Japan
Primary
Secondary
Concomitant
Rectal Ulcer Life Threatening 6/24/2008 71 Female 132 lb 8/4/2008 Physician Japan
Primary
Secondary
Concomitant
Scrotal Ulcer Other Serious 6/30/2008 Male 97 lb 8/18/2008 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Hospitalization 7/28/2008 35 Female 128 lb 8/18/2008 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 7/1/2008 Female 128 lb 8/29/2008 Physician Japan
Primary
Concomitant
Scrotal Ulcer Other Serious 6/30/2008 Male 97 lb 8/29/2008 Physician Japan
Primary
Concomitant
Rectal Ulcer Other Serious 6/24/2008 Female 132 lb 9/29/2008 Physician Japan
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 6/24/2008 Female 132 lb 10/13/2008 Physician Japan
Primary
Secondary
Concomitant
Intestinal Ischaemia Death 1/11/2008 Female 117 lb 11/10/2008 Other Health Professional Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 7/25/2008 Female 128 lb 12/29/2008 Physician Japan
Primary
Concomitant
Oral Disorder Other Serious 12/8/2008 Male 146 lb 1/19/2009 Physician Japan
Primary
Concomitant
Malaise Hospitalization 11/1/2008 Male 146 lb 1/23/2009 Physician Japan
Primary
Concomitant
Oral Disorder Other Serious 12/8/2008 Male 146 lb 2/2/2009 Physician Japan
Primary
Concomitant
Wound Treatment Other Serious 1/23/2008 Female 134 lb 3/24/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 9/16/2008 68 Female 143 lb 4/1/2009 Physician Japan
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/23/2008 Female 134 lb 5/27/2009 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 5/13/2009 Male 115 lb 6/22/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 7/1/2009 77 Male 7/21/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/3/2009 Female 8/11/2009 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 7/20/2009 Female 137 lb 8/13/2009 Physician Japan
Primary
Secondary
Vomiting Hospitalization 7/3/2009 Female 8/27/2009 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/30/2009 Male 126 lb 9/3/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 7/20/2009 Female 137 lb 9/9/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Death 1/25/2008 Female 9/21/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/3/2009 Female 10/5/2009 Other Health Professional Japan
Primary
Concomitant
Rash Erythematous Hospitalization 7/16/2009 61 Female 10/7/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/1/2009 Female 10/13/2009 Physician Japan
Primary
Concomitant
Malignant Pleural Effusion Death 1/1/2008 53 Female 95 lb 10/16/2009 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 5/13/2009 Male 115 lb 10/27/2009 Physician Japan
Primary
Secondary
Concomitant
Jaundice Hospitalization 9/25/2009 Female 90 lb 11/4/2009 Pharmacist Japan
Primary
Concomitant
Paronychia Hospitalization 61 Female 11/18/2009 Physician Japan
Primary
Secondary
Concomitant
Jaundice Hospitalization 9/25/2009 Female 90 lb 12/8/2009 Pharmacist Japan
Primary
Concomitant
Leukoencephalopathy Other Serious 7/1/2009 Female 108 lb 1/19/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/3/2009 Female 134 lb 1/20/2010 Other Health Professional Japan
Primary
Concomitant
Nausea Hospitalization 10/12/2009 Female 101 lb 2/10/2010 Physician Japan
Primary
Concomitant
Nausea Hospitalization 1/15/2010 Male 124 lb 2/16/2010 Other Health Professional Japan
Primary
Concomitant
Leukoencephalopathy Other Serious 7/1/2009 Female 108 lb 2/18/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Death 3/21/2009 Female 2/22/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/27/2009 Female 89 lb 3/4/2010 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 10/12/2009 Female 101 lb 3/16/2010 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 2/5/2010 Female 3/16/2010 Physician Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 1/1/2009 Male 112 lb 3/18/2010 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 9/16/2008 68 Female 143 lb 3/23/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 3/21/2009 Female 3/23/2010 Physician Japan
Primary
Concomitant
Paronychia Hospitalization 9/22/2009 Female 112 lb 3/24/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/1/2009 Female 3/24/2010 Physician Japan
Primary
Concomitant
Retinal Oedema Other Serious 1/29/2010 Male 108 lb 3/30/2010 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 2/5/2010 Female 3/31/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 12/28/2009 74 Male 139 lb 4/21/2010 Physician Japan
Primary
Concomitant
Anaphylactic Shock Life Threatening 4/15/2010 69 Male 4/27/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 7/16/2009 59 Female 88 lb 4/30/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Nausea Death 7/17/2009 37 Female 106 lb 5/3/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 8/24/2009 60 Female 5/5/2010 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 5/10/2009 68 Female 128 lb 5/14/2010 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 5/10/2009 68 Female 128 lb 5/17/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 8/1/2009 48 Female 148 lb 5/18/2010 Physician Japan
Primary
Concomitant
Nausea Death 7/17/2009 37 Female 106 lb 5/25/2010 Physician Japan
Primary
Concomitant
Pancytopenia Death 12/28/2009 74 Male 139 lb 5/27/2010 Physician Japan
Primary
Concomitant
Nausea Hospitalization 11/13/2009 51 Male 124 lb 5/28/2010 Other Health Professional Japan
Primary
Concomitant
Neuropathy Peripheral Life Threatening 12/17/2009 69 Male 128 lb 6/1/2010 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Perforation Other Serious 11/1/2008 60 Male 119 lb 6/8/2010 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 5/10/2009 68 Female 128 lb 6/22/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 11/18/2009 65 Female 93 lb 6/23/2010 Physician Japan
Primary
Concomitant
Jaundice Hospitalization 9/25/2009 79 Female 90 lb 7/7/2010 Pharmacist Japan
Primary
Concomitant
Hypertriglyceridaemia Other Serious Male 7/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/20/2010 66 Male 7/23/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2007 28 Female 97 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 3/15/2010 61 Female 97 lb 8/4/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/20/2010 66 Male 8/6/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 7/6/2010 31 Female 97 lb 8/10/2010 Physician Japan
Primary
Secondary
Concomitant
Wheezing Life Threatening 7/30/2010 75 Female 106 lb 8/17/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Malaise Other Serious 2/25/2010 56 Female 8/17/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 7/5/2010 65 Male 115 lb 8/18/2010 Physician Japan
Primary
Concomitant
Joint Contracture Other Serious 3/23/2010 58 Male 143 lb 8/20/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 12/25/2009 362 Female 90 lb 8/24/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/20/2010 66 Male 176 lb 8/26/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2010 41 Female 112 lb 9/2/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Pustular Hospitalization 9/3/2009 58 Female 112 lb 9/2/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/20/2010 66 Male 9/7/2010 Physician Japan
Primary
Secondary
Concomitant
Wheezing Life Threatening 7/30/2010 75 Female 106 lb 9/7/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Ovarian Torsion Other Serious 10/2/2008 41 Female 119 lb 9/9/2010 Physician Japan
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 9/25/2009 79 Female 90 lb 9/10/2010 Pharmacist Japan
Primary
Concomitant
Sepsis Death 11/18/2009 65 Female 93 lb 9/15/2010 Physician Japan
Primary
Concomitant
Malaise Other Serious 2/25/2010 54 Female 99 lb 9/15/2010 Physician Japan
Primary
Secondary
Concomitant
Ovarian Torsion Other Serious 10/2/2008 41 Female 119 lb 9/21/2010 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased 6/2/2010 41 Female 112 lb 9/22/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/5/2009 49 Female 99 lb 9/22/2010 Physician Japan
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 6/4/2010 49 Female 128 lb 9/23/2010 Physician Japan
Primary
Concomitant
Rectal Perforation Life Threatening 6/29/2010 75 Female 75 lb 9/24/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/29/2008 52 Female 9/27/2010 Physician Japan
Primary
Concomitant
Rectal Perforation Life Threatening 6/29/2010 Female 9/28/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/25/2009 62 Female 90 lb 9/28/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 3/15/2010 61 Female 97 lb 10/6/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 9/9/2010 69 Male 93 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 9/9/2010 69 Male 93 lb 10/11/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 9/9/2010 69 Male 93 lb 10/12/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 9/9/2010 69 Male 10/13/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 9/9/2010 69 Male 93 lb 10/13/2010 Physician Japan
Primary
Secondary
Concomitant
Rectal Perforation Other Serious 4/28/2010 62 Female 106 lb 10/26/2010 Physician Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 8/27/2009 60 Female 106 lb 10/28/2010 Physician Japan
Primary
Secondary
Concomitant
Rectal Perforation Life Threatening 6/29/2010 75 Female 75 lb 11/4/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 8/1/2009 48 Female 148 lb 11/11/2010 Physician Japan
Primary
Concomitant
Splenic Infarction 8/24/2010 67 Male 112 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Arthralgia Other Serious 9/17/2010 60 Female 112 lb 12/1/2010 Pharmacist Japan
Primary
Concomitant
Pyrexia Hospitalization 6/4/2010 49 Female 128 lb 12/6/2010 Physician Japan
Primary
Concomitant
Paronychia Other Serious 4/7/2010 71 Female 106 lb 12/13/2010 Physician Japan
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 11/17/2010 59 Female 121 lb 12/17/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 10/28/2010 56 Female 123 lb 12/20/2010 Physician Japan
Primary
Secondary
Concomitant
Vertigo Hospitalization 10/28/2010 56 Female 123 lb 12/22/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 10/28/2010 56 Female 123 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 7/30/2010 75 Female 106 lb 12/29/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Dizziness 8/27/2009 60 Female 106 lb 1/5/2011 Physician Japan
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 4/7/2010 71 Female 106 lb 1/5/2011 Physician Japan
Primary
Secondary
Concomitant
Anaemia Other Serious 7/8/2010 62 Female 97 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 2/22/2010 72 Male 123 lb 1/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Disability 4/15/2010 80 Female 142 lb 1/19/2011 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 10/3/2010 66 Female 143 lb 1/20/2011 Other Health Professional Japan
Primary
Concomitant
Shock Hospitalization 9/16/2008 68 Female 143 lb 1/24/2011 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 8/1/2010 68 Male 115 lb 1/25/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/27/2010 62 Female 121 lb 1/26/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 6/27/2009 59 Female 106 lb 2/1/2011 Consumer Japan
Primary
Secondary
Concomitant
Depression Hospitalization 11/17/2010 59 Female 119 lb 2/2/2011 Physician Japan
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 8/5/2010 59 Male 157 lb 2/3/2011 Physician Japan
Primary
Concomitant
Cardio-respiratory Arrest Death 12/10/2010 77 Female 137 lb 2/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 8/1/2010 68 Male 2/8/2011 Physician Japan
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Other Serious 6/3/2010 39 Female 134 lb 2/8/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Pain Death 12/10/2010 77 Female 137 lb 2/11/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchitis Life Threatening 1/1/2010 68 Female 123 lb 2/14/2011 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Hospitalization 11/17/2010 59 Female 119 lb 2/14/2011 Physician Japan
Primary
Secondary
Gastrointestinal Perforation Other Serious 8/23/2010 72 Male 120 lb 2/15/2011 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 10/3/2010 66 Female 143 lb 2/16/2011 Pharmacist Japan
Primary
Concomitant
Abdominal Pain Death 12/10/2010 77 Female 137 lb 2/17/2011 Physician Japan
Primary
Secondary
Concomitant
Malignant Pleural Effusion Hospitalization 76 Female 2/17/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Other Serious 6/3/2010 39 Female 134 lb 2/25/2011 Physician Japan
Primary
Secondary
Concomitant
Listless Other Serious 11/17/2010 59 Female 121 lb 3/2/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Cellulitis Hospitalization 7/7/2010 55 Female 97 lb 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Death 7/12/2009 56 Female 99 lb 3/9/2011 Physician Japan
Primary
Concomitant
Enterocolitis Haemorrhagic Other Serious 1/28/2011 67 Female 128 lb 3/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Melaena Death 11/5/2010 77 Female 121 lb 3/15/2011 Physician Japan
Primary
Secondary
Concomitant
Protein Urine Present Hospitalization 8/20/2010 65 Male 141 lb 3/16/2011 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data