Pydoxal combined with Tykerb

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 7/3/2009 Female 8/11/2009 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 7/20/2009 Female 137 lb 8/13/2009 Physician Japan
Primary
Secondary
Vomiting Hospitalization 7/3/2009 Female 8/27/2009 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 7/20/2009 Female 137 lb 9/9/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/3/2009 Female 10/5/2009 Other Health Professional Japan
Primary
Concomitant
Rash Erythematous Hospitalization 7/16/2009 61 Female 10/7/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/1/2009 Female 10/13/2009 Physician Japan
Primary
Concomitant
Jaundice Hospitalization 9/25/2009 Female 90 lb 11/4/2009 Pharmacist Japan
Primary
Concomitant
Paronychia Hospitalization 61 Female 11/18/2009 Physician Japan
Primary
Secondary
Concomitant
Jaundice Hospitalization 9/25/2009 Female 90 lb 12/8/2009 Pharmacist Japan
Primary
Concomitant
Vomiting Hospitalization 7/3/2009 Female 134 lb 1/20/2010 Other Health Professional Japan
Primary
Concomitant
Nausea Hospitalization 10/12/2009 Female 101 lb 2/10/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/27/2009 Female 89 lb 3/4/2010 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 10/12/2009 Female 101 lb 3/16/2010 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 2/5/2010 Female 3/16/2010 Physician Japan
Primary
Secondary
Concomitant
Paronychia Hospitalization 9/22/2009 Female 112 lb 3/24/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/1/2009 Female 3/24/2010 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 2/5/2010 Female 3/31/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 7/16/2009 59 Female 88 lb 4/30/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Nausea Death 7/17/2009 37 Female 106 lb 5/3/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 8/24/2009 60 Female 5/5/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 8/1/2009 48 Female 148 lb 5/18/2010 Physician Japan
Primary
Concomitant
Nausea Death 7/17/2009 37 Female 106 lb 5/25/2010 Physician Japan
Primary
Concomitant
Sepsis Death 11/18/2009 65 Female 93 lb 6/23/2010 Physician Japan
Primary
Concomitant
Jaundice Hospitalization 9/25/2009 79 Female 90 lb 7/7/2010 Pharmacist Japan
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 3/15/2010 61 Female 97 lb 8/4/2010 Physician Japan
Primary
Secondary
Concomitant
Wheezing Life Threatening 7/30/2010 75 Female 106 lb 8/17/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Malaise Other Serious 2/25/2010 56 Female 8/17/2010 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 12/25/2009 362 Female 90 lb 8/24/2010 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2010 41 Female 112 lb 9/2/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Pustular Hospitalization 9/3/2009 58 Female 112 lb 9/2/2010 Physician Japan
Primary
Secondary
Concomitant
Wheezing Life Threatening 7/30/2010 75 Female 106 lb 9/7/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 9/25/2009 79 Female 90 lb 9/10/2010 Pharmacist Japan
Primary
Concomitant
Sepsis Death 11/18/2009 65 Female 93 lb 9/15/2010 Physician Japan
Primary
Concomitant
Malaise Other Serious 2/25/2010 54 Female 99 lb 9/15/2010 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased 6/2/2010 41 Female 112 lb 9/22/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/5/2009 49 Female 99 lb 9/22/2010 Physician Japan
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 6/4/2010 49 Female 128 lb 9/23/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/25/2009 62 Female 90 lb 9/28/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 3/15/2010 61 Female 97 lb 10/6/2010 Physician Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 8/27/2009 60 Female 106 lb 10/28/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 8/1/2009 48 Female 148 lb 11/11/2010 Physician Japan
Primary
Concomitant
Arthralgia Other Serious 9/17/2010 60 Female 112 lb 12/1/2010 Pharmacist Japan
Primary
Concomitant
Pyrexia Hospitalization 6/4/2010 49 Female 128 lb 12/6/2010 Physician Japan
Primary
Concomitant
Paronychia Other Serious 4/7/2010 71 Female 106 lb 12/13/2010 Physician Japan
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 11/17/2010 59 Female 121 lb 12/17/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 10/28/2010 56 Female 123 lb 12/20/2010 Physician Japan
Primary
Secondary
Concomitant
Vertigo Hospitalization 10/28/2010 56 Female 123 lb 12/22/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 10/28/2010 56 Female 123 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 7/30/2010 75 Female 106 lb 12/29/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Dizziness 8/27/2009 60 Female 106 lb 1/5/2011 Physician Japan
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 4/7/2010 71 Female 106 lb 1/5/2011 Physician Japan
Primary
Secondary
Concomitant
Anaemia Other Serious 7/8/2010 62 Female 97 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Disability 4/15/2010 80 Female 142 lb 1/19/2011 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/27/2010 62 Female 121 lb 1/26/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 6/27/2009 59 Female 106 lb 2/1/2011 Consumer Japan
Primary
Secondary
Concomitant
Depression Hospitalization 11/17/2010 59 Female 119 lb 2/2/2011 Physician Japan
Primary
Secondary
Seborrhoeic Dermatitis Other Serious 6/3/2010 39 Female 134 lb 2/8/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 11/17/2010 59 Female 119 lb 2/14/2011 Physician Japan
Primary
Secondary
Malignant Pleural Effusion Hospitalization 76 Female 2/17/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Other Serious 6/3/2010 39 Female 134 lb 2/25/2011 Physician Japan
Primary
Secondary
Concomitant
Listless Other Serious 11/17/2010 59 Female 121 lb 3/2/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Cellulitis Hospitalization 7/7/2010 55 Female 97 lb 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Death 7/12/2009 56 Female 99 lb 3/9/2011 Physician Japan
Primary
Concomitant
Vertigo Hospitalization 10/28/2010 56 Female 123 lb 3/24/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Cellulitis Hospitalization 7/7/2010 55 Female 97 lb 3/28/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Death 7/12/2009 56 Female 99 lb 3/28/2011 Physician Japan
Primary
Concomitant
Drug Eruption Hospitalization 7/25/2009 37 Female 106 lb 4/5/2011 Physician Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 4/13/2010 68 Female 93 lb 4/7/2011 Physician Japan
Primary
Secondary
Concomitant
Hypercapnia Life Threatening 8/1/2009 48 Female 148 lb 4/8/2011 Physician Japan
Primary
Concomitant
Nausea Hospitalization 8/16/2010 69 Female 90 lb 4/14/2011 Physician Japan
Primary
Secondary
Concomitant
Urticaria Hospitalization 9/7/2009 49 Female 93 lb 4/18/2011 Physician Japan
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 3/25/2010 66 Female 99 lb 4/20/2011 Physician Japan
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 6/4/2010 49 Female 128 lb 4/22/2011 Physician Japan
Primary
Concomitant
Vertigo Hospitalization 10/28/2010 56 Female 123 lb 4/27/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 5/26/2010 57 Female 132 lb 4/27/2011 Physician Japan
Primary
Concomitant
Dehydration Hospitalization 3/25/2010 66 Female 99 lb 4/28/2011 Physician Japan
Primary
Concomitant
Drug Eruption Hospitalization 7/25/2009 37 Female 106 lb 5/5/2011 Physician Japan
Primary
Concomitant
Vertigo Hospitalization 10/28/2010 56 Female 123 lb 5/17/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 9/3/2009 58 Female 112 lb 6/9/2011 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 12/25/2009 62 Female 90 lb 6/15/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Urticaria Hospitalization 9/5/2009 49 Female 93 lb 7/1/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Hospitalization 6/27/2009 59 Female 106 lb 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Paronychia Hospitalization 11/16/2009 59 Female 128 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 5/23/2011 85 Female 148 lb 7/21/2011 Physician Japan
Primary
Concomitant
Pneumothorax Hospitalization 11/19/2009 60 Female 8/26/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Disability 12/22/2009 67 Female 93 lb 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 4/15/2010 80 Female 93 lb 9/12/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/16/2010 69 Female 90 lb 11/1/2011 Physician Japan
Primary
Secondary
Concomitant
Superior Vena Cava Syndrome Hospitalization 5/6/2010 50 Female 108 lb 11/4/2011 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 12/25/2009 62 Female 90 lb 12/1/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 5/23/2011 85 Female 148 lb 12/14/2011 Physician Japan
Primary
Concomitant
Dehydration Hospitalization 3/25/2010 66 Female 99 lb 1/4/2012 Physician Japan
Primary
Concomitant
Decubitus Ulcer Hospitalization 5/30/2011 67 Female 97 lb 1/20/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 12/22/2009 67 Female 93 lb 1/26/2012 Physician Japan
Primary
Secondary
Concomitant
Decubitus Ulcer Hospitalization 5/30/2011 67 Female 97 lb 2/9/2012 Physician Japan
Primary
Secondary
Concomitant
Brain Oedema Hospitalization 9/5/2011 34 Female 104 lb 2/15/2012 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 7/8/2011 67 Female 106 lb 3/9/2012 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 4/26/2011 43 Female 123 lb 3/9/2012 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 7/8/2011 67 Female 106 lb 3/27/2012 Physician Japan
Primary
Secondary
Concomitant
Infection Hospitalization 6/27/2009 59 Female 106 lb 4/5/2012 Physician Japan
Primary
Secondary
Concomitant
Calculus Ureteric Hospitalization 10/31/2009 44 Female 128 lb 4/6/2012 Physician Japan
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 3/6/2011 76 Female 77 lb 4/25/2012 Physician Japan
Primary
Secondary
Concomitant
Brain Oedema Hospitalization 9/5/2011 34 Female 104 lb 5/2/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Disability 6/10/2011 43 Female 123 lb 5/3/2012 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 12/29/2011 44 Female 86 lb 5/14/2012 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 4/3/2012 82 Female 101 lb 6/14/2012 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 12/27/2010 51 Female 108 lb 7/13/2012 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 12/8/2011 67 Female 137 lb 7/19/2012 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/16/2010 69 Female 90 lb 4/9/2013 Physician Jp
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 6/27/2011 67 Female 106 lb 11/12/2013 Physician Jp
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 4/3/2012 82 Female 101 lb 12/17/2012 Physician Jp
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 12/16/2010 68 Female 8/28/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/13/2012 51 Female 86 lb 10/3/2012 Physician Jp
Primary
Secondary
Concomitant
Subcutaneous Abscess Death 1/20/2012 50 Female 93 lb 9/10/2013 Physician Jp
Primary
Secondary
Concomitant
Anaemia Other Serious 12/1/2011 56 Female 130 lb 10/22/2012 Physician Jp
Primary
Secondary
Concomitant
Stress Cardiomyopathy Other Serious 12/3/2010 81 Female 99 lb 1/8/2013 Physician Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 2/17/2012 64 Female 97 lb 1/28/2013 Physician Jp
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 2/2011 Female 95 lb 1/3/2013 Physician Jp
Primary
Secondary
Concomitant
Pancytopenia Other Serious 7/19/2009 Female 134 lb 1/30/2013 Physician Jp
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/28/2012 Female 126 lb 1/31/2013 Physician Jp
Primary
Secondary
Concomitant
Stomatitis Other Serious 4/16/2010 Female 143 lb 2/1/2013 Physician Jp
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/19/2010 Female 110 lb 2/1/2013 Physician Jp
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/17/2011 Female 132 lb 2/1/2013 Physician Jp
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2011 Female 101 lb 2/1/2013 Physician Jp
Primary
Secondary
Concomitant
Duodenal Ulcer Other Serious 11/30/2011 Female 117 lb 2/1/2013 Physician Jp
Primary
Secondary
Concomitant
Rash Other Serious 11/28/2011 Female 2/1/2013 Physician Jp
Primary
Concomitant
Rash Other Serious 7/10/2009 Female 112 lb 1/31/2013 Physician Jp
Primary
Concomitant
Pigmentation Disorder Other Serious 7/29/2009 Female 121 lb 1/31/2013 Physician Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/12/2009 Female 117 lb 1/31/2013 Physician Jp
Primary
Secondary
Concomitant
Nausea Other Serious 4/21/2010 Female 128 lb 1/31/2013 Physician Jp
Primary
Secondary
Concomitant
Rash Other Serious 4/10/2010 Female 110 lb 1/31/2013 Physician Jp
Primary
Secondary
Concomitant
Stomatitis Other Serious 11/2010 Female 115 lb 1/31/2013 Physician Jp
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/17/2010 Female 139 lb 1/31/2013 Physician Jp
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 5/13/2010 Female 1/31/2013 Physician Jp
Primary
Secondary
Concomitant
Hand Dermatitis Other Serious 8/18/2010 Female 121 lb 1/31/2013 Physician Jp
Primary
Secondary
Concomitant
Sepsis Death 10/4/2010 73 Male 132 lb 4/22/2013 Physician Jp
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/25/2012 41 Female 68 lb 4/9/2013 Physician Jp
Primary
Secondary
Concomitant
Stomatitis Other Serious 10/19/2009 63 Female 106 lb 3/28/2013 Physician Jp
Primary
Secondary
Concomitant
Hyperbilirubinaemia Other Serious 2/22/2010 49 Female 117 lb 3/28/2013 Physician Jp
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/1/2010 60 Female 112 lb 3/28/2013 Physician Jp
Primary
Concomitant
Venous Thrombosis Limb Life Threatening 7/30/2009 58 Female 117 lb 3/28/2013 Physician Jp
Primary
Secondary
Concomitant
Rash Other Serious 3/8/2011 41 Female 93 lb 3/28/2013 Physician Jp
Primary
Secondary
Concomitant
Rash Other Serious 7/29/2010 41 Female 163 lb 6/26/2013 Physician Jp
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/5/2010 47 Female 99 lb 4/2/2013 Physician Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/9/2008 38 Female 99 lb 4/3/2013 Physician Jp
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/29/2009 42 Female 99 lb 4/3/2013 Physician Jp
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Disability 1/19/2010 63 Female 121 lb 4/9/2013 Physician Jp
Primary
Secondary
Concomitant
Malaise Other Serious 2/25/2010 55 Female 99 lb 4/11/2013 Physician Jp
Primary
Secondary
Concomitant
Stomatitis Other Serious 11/18/2010 45 Female 143 lb 4/11/2013 Physician Jp
Primary
Secondary
Concomitant

Drug Data