Provigil combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tremor Other Serious 11/21/2005 64 Female 1/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 11/21/2005 64 Female 133 lb 1/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tendon Injury Disability 8/7/2003 75 Female 178 lb 2/1/2006 Physician United States
Primary
Concomitant
Tremor Other Serious 11/21/2005 64 Female 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash 10/5/2005 58 Female 160 lb 1/5/2006 Consumer United States
Primary
Concomitant
Tremor Hospitalization 11/21/2005 64 Female 133 lb 2/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 11/21/2005 64 Female 132 lb 2/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 1/1/2003 55 Male 240 lb 3/1/2006 United States
Primary
Concomitant
Suicide Attempt Other Serious 53 Female 165 lb 2/24/2006 United States
Primary
Secondary
Concomitant
Troponin I Increased Life Threatening 2/7/2006 31 Female 3/13/2006 Physician United States
Primary
Secondary
Concomitant
Laboratory Test Abnormal Hospitalization 7/1/2004 50 Female 11/29/2004 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 41 Female 1/12/2006 United States
Primary
Concomitant
Road Traffic Accident Other Serious 45 Female 90 lb 3/23/2006 Physician United States
Primary
Concomitant
Vascular Resistance Systemic Increased Life Threatening 2/7/2006 31 Female 3/29/2006 Physician United States
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 6/30/2000 Female 231 lb 5/1/2006 Lawyer United States
Primary
Concomitant
Vascular Resistance Systemic Increased Life Threatening 2/7/2006 31 Female 4/28/2006 Physician United States
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 45 Female 90 lb 5/8/2006 Physician United States
Primary
Concomitant
Visual Disturbance Hospitalization 4/3/2006 29 Female 5/10/2006 United States
Primary
Concomitant
Ventricular Hypokinesia Life Threatening 2/7/2006 31 Female 5/30/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization Female 6/8/2006 Consumer United States
Primary
Secondary
Ejection Fraction Decreased Other Serious 4/12/2006 39 Female 132 lb 6/15/2006 United States
Primary
Concomitant
Suicide Attempt Other Serious 53 Female 165 lb 5/23/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 8/22/2004 Female 10/14/2005 United States
Primary
Concomitant
Drug Ineffective 12/1/2005 49 Female 7/12/2006 Consumer United States
Primary
Concomitant
Neck Pain Hospitalization 11/1/2005 Female 8/7/2006 United States
Primary
Concomitant
Starvation Hospitalization 5/1/2006 46 Female 9/18/2006 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 8/2/2006 14 Female 159 lb 9/15/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 34 Female 100 lb 9/26/2006 Consumer United States
Primary
Concomitant
Traumatic Brain Injury Hospitalization 9/1/2004 32 Female 118 lb 9/26/2006 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 6/1/2005 53 Female 8/18/2006 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 8/2/2006 14 Female 159 lb 11/16/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 46 Female 12/1/2006 United States
Primary
Secondary
Concomitant
Tremor 2/13/2006 24 Female 12/20/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 9/28/2006 35 Female 12/14/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred Hospitalization 11/1/2006 Female 103 lb 1/5/2007 Consumer United States
Primary
Concomitant
Hypotonia Hospitalization 1/1/2006 46 Female 12/29/2006 Consumer United States
Primary
Concomitant
Syncope Other Serious 12/1/1999 Female 1/19/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 2/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 1/1/2007 48 Female 3/9/2007 United States
Primary
Concomitant
Tremor Hospitalization 1/1/2004 Female 132 lb 3/27/2007 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 1/1/2007 48 Female 3/21/2007 Physician United States
Primary
Concomitant
Paranoia Other Serious 49 Female 123 lb 11/28/2006 United States
Primary
Concomitant
Osteoporosis Other Serious 5/1/2002 64 Female 4/11/2007 Consumer United States
Primary
Concomitant
Sedation Other Serious 3/1/2007 Female 175 lb 4/17/2007 Consumer United States
Primary
Concomitant
Interacting
Vomiting Hospitalization 10/1/2006 55 Female 158 lb 4/16/2007 Consumer United States
Primary
Concomitant
Overdose Death 2/13/2007 35 Male 5/4/2007 Consumer United States
Primary
Concomitant
Syncope Other Serious 1/1/2007 52 Female 5/16/2007 United States
Primary
Concomitant
Weight Decreased Other Serious Female 5/25/2007 Consumer United States
Primary
Secondary
Concomitant
Petit Mal Epilepsy Other Serious 5/15/2007 43 Female 5/23/2007 Physician United States
Primary
Concomitant
Swelling Hospitalization 2/8/2007 Female 5/30/2007 Physician United States
Primary
Concomitant
Swelling Hospitalization 2/8/2007 Female 5/30/2007 Physician United States
Primary
Concomitant
Petit Mal Epilepsy Other Serious 5/14/2007 43 Female 175 lb 5/25/2007 Physician United States
Primary
Secondary
Concomitant
Petit Mal Epilepsy Other Serious 5/14/2007 43 Female 175 lb 5/30/2007 Consumer United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 1/1/2006 38 Female 154 lb 6/7/2007 Consumer United States
Primary
Concomitant
Hypersomnia 3/14/2007 34 Female 299 lb 5/11/2007 United States
Primary
Concomitant
Application Site Discolouration Disability 1/1/2005 Female 112 lb 6/27/2007 Physician United States
Primary
Concomitant
White Blood Cell Disorder Other Serious 1/1/2007 Female 266 lb 7/13/2007 Consumer United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2007 52 Female 7/21/2007 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 5/27/2007 59 Female 7/20/2007 Physician United States
Primary
Concomitant
Pitting Oedema 12/1/2006 Female 184 lb 7/26/2007 Physician United States
Primary
Concomitant
Tremor Hospitalization 1/1/2004 Female 132 lb 7/30/2007 Physician United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 1/1/2006 38 Female 154 lb 8/16/2007 Physician United States
Primary
Secondary
Concomitant
Pathological Gambling Male 8/22/2007 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 Female 228 lb 8/24/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/1/2007 56 Female 8/27/2007 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious Male 9/21/2007 Physician United States
Primary
Concomitant
Pathological Gambling 11/9/2005 Female 10/1/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 157 lb 10/12/2007 Consumer United States
Primary
Secondary
Concomitant
Injection Site Haemorrhage Hospitalization 2/1/2007 Male 195 lb 10/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Musculoskeletal Discomfort Other Serious 6/25/2007 Female 146 lb 10/24/2007 Physician United States
Primary
Secondary
Concomitant
Pathological Gambling 11/9/2005 Female 11/5/2007 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 Female 228 lb 11/19/2007 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 11/10/2007 31 Female 12/7/2007 Physician United States
Primary
Secondary
Weight Increased Other Serious 1/1/2007 Female 287 lb 12/26/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 8/27/2004 40 Male 12/6/2007 United States
Primary
Concomitant
Restlessness 11/5/2007 31 Female 220 lb 12/18/2007 United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/15/2008 35 Female 120 lb 1/23/2008 Physician United States
Primary
Concomitant
Fatigue 4/23/2007 35 Female 1/29/2008 Consumer United States
Primary
Secondary
Weight Increased Other Serious Female 180 lb 1/29/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 157 lb 2/7/2008 Physician United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 2/1/2007 Male 280 lb 2/19/2008 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 1/1/2007 37 Female 2/12/2008 United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2006 Female 158 lb 2/25/2008 Consumer United States
Primary
Concomitant
Hepatitis A Hospitalization 1/29/2008 49 Female 154 lb 2/14/2008 Physician Israel
Primary
Concomitant
Pharyngolaryngeal Pain 11/26/2007 34 Female 2/22/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 250 lb 2/28/2008 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2006 36 Female 187 lb 3/10/2008 United States
Primary
Concomitant
Thrombosis Hospitalization 10/7/2007 44 Female 3/17/2008 United States
Primary
Concomitant
Tooth Loss Other Serious Male 160 lb 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/1998 Female 207 lb 4/7/2008 Consumer United States
Primary
Concomitant
Pancytopenia Other Serious 75 Male 4/1/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 75 Male 190 lb 4/7/2008 Other Health Professional United States
Primary
Concomitant
Sedation Hospitalization 1/1/2005 48 Female 200 lb 4/9/2008 United States
Primary
Concomitant
Tremor Other Serious 1/19/2007 Male 4/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious Male 160 lb 4/21/2008 Lawyer United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/1/2006 Female 158 lb 5/15/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2004 Male 5/23/2008 Consumer United States
Primary
Concomitant
Convulsion 35 Female 103 lb 5/27/2008 United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2006 Female 158 lb 6/10/2008 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint 2/21/2008 Female 204 lb 6/6/2008 Pharmacist United States
Primary
Concomitant
Nerve Degeneration Other Serious 5/1/2008 43 Female 154 lb 6/11/2008 Physician United States
Primary
Concomitant
Sinus Disorder Other Serious 4/21/2008 Female 175 lb 6/18/2008 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 3/1/2007 Female 123 lb 7/8/2008 United States
Primary
Secondary
Concomitant
Peroneal Nerve Palsy Hospitalization 3/17/2008 47 Female 130 lb 7/11/2008 United States
Primary
Concomitant
Restless Legs Syndrome Hospitalization 1/1/2005 Female 120 lb 8/7/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 1/1/1999 Female 8/8/2008 Consumer United States
Primary
Concomitant
Hiatus Hernia Hospitalization 1/1/2001 49 Female 8/7/2008 United States
Primary
Concomitant
Condition Aggravated Other Serious 38 Female 215 lb 8/22/2008 United States
Primary
Concomitant
Memory Impairment Other Serious 38 Female 215 lb 9/2/2008 Other Health Professional United States
Primary
Concomitant
Erectile Dysfunction 2/1/2007 44 Male 9/12/2008 Consumer United States
Primary
Concomitant
Lethargy 7/1/2008 47 Female 155 lb 9/16/2008 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/1995 Female 198 lb 10/20/2008 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2007 Female 198 lb 10/22/2008 Consumer United States
Primary
Concomitant
Wound Infection Hospitalization Female 10/22/2008 Consumer United States
Primary
Concomitant
Multiple Congenital Abnormalities Congenital Anomaly 4/1/2008 11/17/2008 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2006 57 Male 240 lb 11/20/2008 United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2007 Female 198 lb 12/11/2008 Consumer United States
Primary
Concomitant
Spinal Nerve Stimulator Implantation Other Serious Female 120 lb 12/19/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/24/2007 56 Female 137 lb 12/17/2008 Other Health Professional United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 9/1/2008 68 Female 1/28/2009 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 11/1/2008 43 Female 1/27/2009 United States
Primary
Concomitant
Peroneal Nerve Palsy Other Serious 3/21/2008 47 Female 130 lb 2/3/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2007 61 Female 172 lb 2/12/2009 Other Health Professional United States
Primary
Concomitant
Spinal Nerve Stimulator Implantation Other Serious 1/23/2006 Female 120 lb 2/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 9/1/2008 68 Female 3/5/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2007 61 Female 172 lb 3/13/2009 Other Health Professional United States
Primary
Concomitant
Headache 1/1/2007 Female 156 lb 3/14/2009 Consumer United States
Primary
Concomitant
Pruritus Other Serious 12/31/2008 Female 3/18/2009 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 45 Female 115 lb 3/18/2009 United States
Primary
Concomitant
Speech Disorder Other Serious 39 Female 220 lb 3/24/2009 Consumer United States
Primary
Concomitant
Abortion Spontaneous Other Serious 3/20/2009 35 Female 4/2/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 39 Female 4/3/2009 United States
Primary
Concomitant
Speech Disorder Other Serious 39 Female 220 lb 4/7/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2007 61 Female 172 lb 4/9/2009 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 1/22/2009 35 Female 4/9/2009 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2008 68 Female 231 lb 4/10/2009 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 1/22/2009 35 Female 4/16/2009 Other Health Professional United States
Primary
Concomitant
Vocal Cord Disorder Other Serious 11/1/2007 56 Male 380 lb 4/17/2009 Lawyer United States
Primary
Concomitant
Urticaria Hospitalization 12/5/2007 68 Female 229 lb 4/23/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2007 61 Female 172 lb 4/30/2009 Other Health Professional United States
Primary
Concomitant
Speech Disorder Disability 1/1/2009 33 Female 195 lb 3/27/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Life Threatening 4/27/2009 42 Female 5/15/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 6/2/2009 United States
Primary
Secondary
Concomitant
Pain In Extremity Female 6/11/2009 United States
Primary
Concomitant
Traumatic Brain Injury Life Threatening 4/27/2009 42 Female 6/12/2009 Consumer United States
Primary
Secondary
Concomitant
Fatigue 60 Female 6/22/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 33 Female 6/22/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 6/30/2009 United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 12/24/2008 47 Female 183 lb 7/2/2009 Other Health Professional United States
Primary
Concomitant
Iud Migration Other Serious 1/1/2008 48 Female 157 lb 7/8/2009 Other Health Professional United States
Primary
Concomitant

Drug Data