Propofol combined with Vecuronium Bromide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Procedural Complication Life Threatening 42 Female 1/2/2006 Physician Japan
Primary
Secondary
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Post Procedural Complication Required Intervention 10/4/2005 52 Female 10/31/2005 Pharmacist United States
Primary
Secondary
Concomitant
Spinal Cord Infarction Other Serious 83 Male 1/19/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Spinal Cord Infarction Disability 83 Male 1/19/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 1/24/2006 Japan
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia 6/17/2005 Female 1/24/2006 Japan
Primary
Secondary
Concomitant
Somnolence Hospitalization 25 Female 132 lb 1/26/2006 Other Health Professional India
Primary
Secondary
Concomitant
Somnolence Hospitalization 25 Female 132 lb 1/26/2006 Other Health Professional India
Primary
Secondary
Concomitant
Injection Site Swelling Hospitalization 1/16/2006 55 Male 2/14/2006 Japan
Primary
Concomitant
Blood Pressure Diastolic Increased Life Threatening 4/20/2005 23 Female 2/27/2006 Japan
Primary
Secondary
Liver Disorder Hospitalization 1/30/2006 53 Male 3/8/2006 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Required Intervention 12/13/2005 57 Male 148 lb 3/2/2006 Physician Japan
Primary
Secondary
Concomitant
Swollen Tongue 1/1/2005 32 Female 3/15/2006 Consumer United States
Primary
Secondary
Concomitant
Shock Life Threatening 4/20/2005 23 Female 3/9/2006 Japan
Primary
Secondary
Liver Disorder Hospitalization 1/30/2006 53 Male 3/21/2006 Physician Japan
Primary
Concomitant
Neuromuscular Block Prolonged Required Intervention 35 Female 112 lb 3/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Myopathy Hospitalization 15 Female 192 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Procedural Complication 3/15/2006 37 Female 3/31/2006 Japan
Primary
Concomitant
Tachycardia Life Threatening 3/20/2006 37 Female 4/5/2006 Norway
Primary
Concomitant
Pain In Extremity Hospitalization 10/15/2003 45 Male 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/10/2006 38 Male 176 lb 4/5/2006 Physician United States
Primary
Concomitant
Respiratory Failure 3/15/2006 37 Female 4/12/2006 Physician Japan
Primary
Concomitant
Polyuria Other Serious 3/7/2006 59 Female 4/24/2006 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/13/2005 49 Female 265 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Thirst Other Serious 59 Female 4/28/2006 Consumer Japan
Primary
Secondary
Concomitant
Thirst Other Serious 59 Female 5/1/2006 Consumer Japan
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 5/12/2005 60 Female 4/28/2006 France
Primary
Secondary
Anaphylactic Shock 4/26/2006 44 Male 5/5/2006 Italy
Primary
Secondary
Vomiting Hospitalization 7/10/2005 54 Female 5/24/2006 Pharmacist Australia
Primary
Secondary
Concomitant
Operative Haemorrhage 1/25/2006 67 Male 5/19/2006 Other Health Professional Japan
Primary
Secondary
Blood Pressure Decreased 60 Female 5/24/2006 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 62 Female 106 lb 6/6/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 47 Male 6/6/2006 Other Health Professional Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 21 Male 203 lb 6/8/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 67 Male 139 lb 6/8/2006 Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 59 Male 106 lb 6/12/2006 Other Health Professional Japan
Primary
Concomitant
Interacting
Skin Exfoliation Other Serious 1/20/2006 55 Male 5/29/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 71 Male 112 lb 6/14/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 67 Male 139 lb 6/14/2006 Japan
Primary
Secondary
Concomitant
Procedural Complication 6/1/2005 59 Male 106 lb 6/15/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 47 Male 6/16/2006 Other Health Professional Japan
Primary
Concomitant
Post Procedural Haemorrhage 1/25/2006 67 Male 6/12/2006 Japan
Primary
Secondary
Ventricular Tachycardia Other Serious 62 Female 106 lb 6/20/2006 Other Health Professional Japan
Primary
Concomitant
Chills Other Serious 57 Male 128 lb 6/20/2006 Japan
Primary
Secondary
Atelectasis Life Threatening 5/16/2005 84 Female 6/20/2006 Physician Japan
Primary
Concomitant
Chills Other Serious 10/18/2005 Male 128 lb 6/28/2006 Japan
Primary
Secondary
Concomitant
Airway Complication Of Anaesthesia 60 Female 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Procedural Hypotension Life Threatening 5/16/2006 78 Male 7/26/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 50 Female 88 lb 7/20/2006 Physician India
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 8/7/2006 Other Health Professional Japan
Primary
Concomitant
Anaphylactic Reaction Life Threatening 2/13/2006 65 Female 7/28/2006 Australia
Primary
Secondary
Rash Erythematous Life Threatening 2/13/2006 65 Female 7/25/2006 Australia
Primary
Secondary
Tachycardia 4/26/2006 44 Female 7/28/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Shock Life Threatening 7/25/2006 62 Female 9/1/2006 Other Health Professional Japan
Primary
Concomitant
Delayed Recovery From Anaesthesia Hospitalization 8/2/2006 67 Male 9/4/2006 Japan
Primary
Secondary
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 9/18/2006 Other Health Professional Japan
Primary
Concomitant
Shock Life Threatening 7/25/2006 62 Female 9/25/2006 Other Health Professional Japan
Primary
Concomitant
Electrocardiogram Qrs Complex Prolonged Other Serious 63 Female 128 lb 9/25/2006 Japan
Primary
Secondary
Concomitant
Procedural Complication Hospitalization 8/2/2006 67 Male 9/22/2006 Japan
Primary
Secondary
Concomitant
Shock Life Threatening 7/25/2006 62 Female 10/6/2006 Other Health Professional Japan
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 127 lb 10/23/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Dysfunction Other Serious 21 Male 174 lb 10/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 68 Male 143 lb 10/23/2006 Physician Japan
Primary
Concomitant
Anaphylactic Reaction Life Threatening 9/14/2006 43 Male 10/18/2006 Norway
Primary
Secondary
Concomitant
Bronchospasm Life Threatening 1/13/2006 17 Female 10/18/2006 Japan
Primary
Concomitant
Acute Myocardial Infarction Other Serious 80 Male 10/30/2006 Japan
Primary
Concomitant
Thrombocytopenia Other Serious 64 Male 196 lb 10/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 70 Male 11/3/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/6/2006
Primary
Concomitant
Pulmonary Hypertension Other Serious 11/6/2006
Primary
Concomitant
Lung Disorder Other Serious 11/6/2006
Primary
Concomitant
Acute Myocardial Infarction Other Serious 80 Male 11/8/2006 Japan
Primary
Concomitant
Acute Myocardial Infarction Other Serious 80 Male 11/8/2006 Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 81 Male 11/6/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 11/14/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypoxia Life Threatening 75 Male 11/16/2006 Japan
Primary
Concomitant
Anaphylactoid Reaction 32 Female 11/7/2006 Other Health Professional Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 84 Female 11/17/2006 Japan
Primary
Secondary
Concomitant
Respiratory Tract Haemorrhage Life Threatening 75 Male 11/20/2006 Japan
Primary
Concomitant
Anaphylactic Shock 73 Female 11/9/2006 Physician Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 84 Female 11/21/2006 Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 55 Female 121 lb 11/27/2006 Other Health Professional Japan
Primary
Concomitant
Respiratory Disorder Other Serious 28 Female 11/8/2006 Japan
Primary
Concomitant
Procedural Complication 32 Female 11/15/2006 Japan
Primary
Concomitant
Hypoxia Life Threatening 6/3/2006 Male 11/30/2006 Japan
Primary
Concomitant
Retinal Artery Occlusion Disability 49 Female 121 lb 11/30/2006 Physician China
Primary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 94 lb 12/4/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 3/1/2005 71 Male 137 lb 11/22/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/5/2006 Female 12/6/2006 Japan
Primary
Concomitant
Urticaria Other Serious 5/2/2006 32 Female 12/7/2006 Physician Japan
Primary
Secondary
Concomitant
Erythema Life Threatening 5/2/2006 32 Female 11/29/2006 Japan
Primary
Secondary
Concomitant
Blood Pressure Systolic Decreased Life Threatening 5/2/2006 32 Female 11/24/2006 Japan
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 4/22/2006 Male 12/18/2006 Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 8/29/2005 81 Male 12/12/2006 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Life Threatening 46 Female 12/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ultrasound Scan Abnormal Other Serious 46 Female 12/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 46 Female 12/21/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 46 Female 12/22/2006
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 94 lb 12/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 46 Female 12/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Required Intervention 1/1/2006 46 Female 12/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 10/30/2006 46 Female 12/22/2006 United Kingdom
Primary
Secondary
Concomitant
Stridor Life Threatening 5/31/2006 55 Male 12/22/2006 Japan
Primary
Secondary
Concomitant
Vomiting Required Intervention 9/1/2006 73 Female 12/28/2006 Physician Japan
Primary
Concomitant
Tachypnoea Life Threatening 46 Female 12/30/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 28 Female 12/28/2006 Other Health Professional Japan
Primary
Concomitant
Nasopharyngeal Disorder Life Threatening 5/31/2006 55 Male 1/10/2007 Japan
Primary
Secondary
Concomitant
Tachypnoea Other Serious 46 Female 1/15/2007 United Kingdom
Primary
Secondary
Concomitant
Unwanted Awareness During Anaesthesia Other Serious Male 1/23/2007
Primary
Secondary
Drug Hypersensitivity Life Threatening 11/7/2006 26 Female 1/24/2007 Japan
Primary
Concomitant
Renal Failure Acute Other Serious 40 Female 2/2/2007 Other Health Professional India
Primary
Concomitant
Pharyngolaryngeal Pain Life Threatening 11/7/2006 26 Female 1/26/2007 Japan
Primary
Concomitant
Renal Failure Acute Other Serious 40 Female 2/7/2007 Other Health Professional India
Primary
Concomitant
Sinus Bradycardia Hospitalization 64 Male 2/6/2007 Japan
Primary
Concomitant
Wound Treatment Other Serious 40 Female 2/21/2007 Other Health Professional India
Primary
Concomitant
Psychotic Disorder Other Serious Male 2/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious Male 2/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Uterine Hypertonus 2/23/2007 Japan
Primary
Concomitant
Wound Treatment Other Serious 40 Female 3/2/2007 Other Health Professional India
Primary
Concomitant
Pulmonary Embolism Other Serious 7/5/2006 Female 3/9/2007 Japan
Primary
Concomitant
Uterine Contractions During Pregnancy 9/13/2005 3/22/2007 Japan
Primary
Secondary
Syncope Vasovagal Life Threatening 10/22/2004 64 Male 3/21/2007 Japan
Primary
Secondary
Hot Flush Other Serious 12/28/2005 24 Male 132 lb 4/2/2007 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/30/2007 Male 84 lb 4/4/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Laryngeal Oedema Life Threatening 3/26/2007 51 Female 4/6/2007 Japan
Primary
Secondary
Concomitant
Hot Flush Other Serious 3/29/2007 72 Male 4/16/2007 Consumer Japan
Primary
Concomitant
Hypotension Life Threatening 4/6/2007 54 Female 4/17/2007 Consumer Italy
Primary
Concomitant
Sinus Arrest Life Threatening 40 Female 4/10/2007 Japan
Primary
Secondary
Concomitant
Laryngeal Oedema Life Threatening 3/26/2007 51 Female 4/11/2007 Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 66 Male 4/24/2007 United States
Primary
Secondary
Concomitant
Sinus Arrest Life Threatening 40 Female 4/17/2007 Japan
Primary
Secondary
Concomitant
Arteriospasm Coronary Other Serious 70 Female 101 lb 4/24/2007 Other Health Professional Japan
Primary
Concomitant
Sepsis Hospitalization 66 Male 4/27/2007 United States
Primary
Secondary
Concomitant
Hot Flush Other Serious 3/29/2007 72 Male 119 lb 4/30/2007 Consumer Japan
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 3/26/2007 50 Female 4/30/2007 Physician Japan
Primary
Secondary
Laryngeal Oedema Life Threatening 3/26/2007 51 Female 4/23/2007 Japan
Primary
Secondary
Concomitant
Hot Flush Other Serious 3/29/2007 72 Male 119 lb 5/3/2007 Consumer Japan
Primary
Concomitant
Procedural Complication Hospitalization 9/13/1999 76 Female 4/27/2007 France
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 3/26/2007 50 Female 5/9/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 3/26/2007 51 Female 112 lb 5/14/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 12 Male 5/15/2007 Japan
Primary
Concomitant
Hypersensitivity Life Threatening 4/27/2007 3 Female 5/16/2007 Norway
Primary
Secondary
Concomitant
Hot Flush Other Serious 3/29/2007 72 Male 119 lb 5/22/2007 Consumer Japan
Primary
Concomitant
Wheezing Disability 4/5/2007 74 Male 160 lb 5/18/2007 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 12 Male 5/24/2007 Japan
Primary
Concomitant
Respiratory Arrest Life Threatening 10/20/2006 74 Male 5/22/2007 Japan
Primary
Concomitant
Sinus Bradycardia Hospitalization 64 Male 3/20/2007 Japan
Primary
Concomitant
Tongue Oedema Required Intervention 51 Female 139 lb 2/22/2007 Physician United States
Primary
Concomitant
Lung Disorder Other Serious 58 Male 6/28/2007 Other Health Professional Japan
Primary
Concomitant

Drug Data