Propofol combined with Sevoflurane

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Procedural Complication Life Threatening 42 Female 1/2/2006 Physician Japan
Primary
Secondary
Sleep Apnoea Syndrome Hospitalization 1/24/2005 2 Female 24 lb 1/4/2006 Physician Japan
Primary
Concomitant
Blood Creatinine Increased 2/16/2005 69 218 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Blood Creatinine Increased 2/16/2005 69 218 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Renal Impairment Disability 12/10/2005 80 Male 126 lb 1/12/2006 Physician Japan
Primary
Concomitant
Spinal Cord Infarction Other Serious 83 Male 1/19/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Spinal Cord Infarction Disability 83 Male 1/19/2006 Other Health Professional Japan
Primary
Concomitant
Cerebrovascular Accident Hospitalization 1/21/2005 Male 185 lb 1/19/2006 Australia
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 1/24/2006 Japan
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia 6/17/2005 Female 1/24/2006 Japan
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Required Intervention 12/7/2005 56 Male 97 lb 1/20/2006 Physician Japan
Primary
Concomitant
Wheezing Other Serious 24 Male 2/24/2006 Physician Germany
Primary
Concomitant
Injection Site Swelling Hospitalization 1/16/2006 55 Male 2/14/2006 Japan
Primary
Concomitant
Drug Ineffective 11/25/2005 50 Male 2/15/2006 Other Health Professional Portugal
Primary
Concomitant
Myoglobin Blood Increased Life Threatening 12/18/2005 44 Male 2/22/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Impairment Required Intervention 5/25/2005 68 Male 149 lb 3/1/2006 Physician Japan
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 8 Male 64 lb 3/9/2006 France
Primary
Concomitant
Hepatic Function Abnormal Required Intervention 12/13/2005 57 Male 148 lb 3/2/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 30 Male 161 lb 3/10/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 1/13/2006 43 Female 146 lb 3/7/2006 Physician France
Primary
Secondary
Concomitant
Nausea Hospitalization 38 Male 220 lb 3/16/2006 Other Health Professional United States
Primary
Concomitant
Mental Status Changes Life Threatening 6/14/2004 49 Female 3/14/2006 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2001 31 Male 183 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Hypotension Other Serious 2/21/2006 Male 4/4/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 74 Female 4/5/2006 Physician France
Primary
Secondary
Liver Function Test Abnormal Hospitalization 3/21/2006 Female 4/7/2006 Physician Germany
Primary
Concomitant
Procedural Complication 3/15/2006 37 Female 3/31/2006 Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/13/2006 43 Female 146 lb 4/3/2006 Physician France
Primary
Secondary
Concomitant
Neuromuscular Block Prolonged Required Intervention 12/5/2005 34 Female 160 lb 12/5/2005 Physician United States
Primary
Concomitant
Hepatitis Fulminant Hospitalization 1/3/2006 28 Female 4/14/2006 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure 3/15/2006 37 Female 4/12/2006 Physician Japan
Primary
Concomitant
Shock Hospitalization 3/28/2006 68 Male 128 lb 4/20/2006 Physician Japan
Primary
Concomitant
Polyuria Other Serious 3/7/2006 59 Female 4/24/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 30 Male 161 lb 4/11/2006 Physician Spain
Primary
Secondary
Concomitant
Hypotension Other Serious 74 Female 110 lb 4/20/2006 Physician Japan
Primary
Secondary
Concomitant
Thirst Other Serious 59 Female 4/28/2006 Consumer Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/28/2006 68 Male 128 lb 5/1/2006 Physician Japan
Primary
Concomitant
Thirst Other Serious 59 Female 5/1/2006 Consumer Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 3/21/2006 Female 5/9/2006 Physician Germany
Primary
Secondary
Concomitant
Rash Other Serious 4/13/2006 52 Male 190 lb 5/10/2006 Consumer United Kingdom
Primary
Concomitant
Anaphylactic Shock 4/26/2006 44 Male 5/5/2006 Italy
Primary
Secondary
Respiratory Depression Required Intervention 21 Male 77 lb 5/12/2006 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/13/2006 43 Female 146 lb 5/23/2006 Physician France
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 35 Female 116 lb 5/23/2006 Physician China
Primary
Secondary
Concomitant
Blood Pressure Decreased 60 Female 5/24/2006 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 47 Male 6/6/2006 Other Health Professional Japan
Primary
Concomitant
Somnolence Hospitalization 3/21/2006 43 Male 216 lb 5/31/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 21 Male 203 lb 6/8/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 22 Male 6/8/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 67 Male 139 lb 6/8/2006 Japan
Primary
Secondary
Concomitant
Priapism Other Serious 17 Male 6/9/2006 Other Health Professional United States
Primary
Concomitant
Skin Exfoliation Other Serious 1/20/2006 55 Male 5/29/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 67 Male 139 lb 6/14/2006 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 47 Male 6/16/2006 Other Health Professional Japan
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 5/31/2006 41 Female 163 lb 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 65 Male 6/20/2006 United Kingdom
Primary
Concomitant
Therapy Non-responder Other Serious 74 Female 110 lb 6/29/2006 Physician Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 22 Male 7/5/2006 Other Health Professional Japan
Primary
Concomitant
Cardio-respiratory Arrest Death 6/27/2006 13 Male 7/10/2006 Physician Chile
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 3/21/2006 Female 7/10/2006 Physician Germany
Primary
Secondary
Concomitant
Airway Complication Of Anaesthesia 60 Female 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/21/2006 44 Male 216 lb 7/14/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Hypotension Other Serious 4/20/2005 72 Female 71 lb 7/21/2006 Japan
Primary
Secondary
Concomitant
Hypotension Other Serious 4/20/2005 72 Female 71 lb 7/28/2006 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 8/30/2005 48 Male 8/7/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 8/7/2006 Other Health Professional Japan
Primary
Concomitant
Tryptase Increased Other Serious Female 8/9/2006 Physician Ireland
Primary
Concomitant
Tachycardia 4/26/2006 44 Female 7/28/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/22/2005 65 Male 176 lb 8/4/2006 United Kingdom
Primary
Concomitant
Splenomegaly Hospitalization 3/21/2006 Female 8/10/2006 Physician Germany
Primary
Secondary
Concomitant
Neuromuscular Block Prolonged Hospitalization 4/24/2006 32 Female 8/11/2006 South Africa
Primary
Concomitant
Wound Secretion Other Serious 35 Female 116 lb 9/1/2006 Other Health Professional China
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 9/18/2006 Other Health Professional Japan
Primary
Concomitant
Hepatic Failure Other Serious 1 Female 11 lb 9/27/2006 United States
Primary
Concomitant
Wound Dehiscence Other Serious 35 Female 116 lb 9/28/2006 United States
Primary
Concomitant
Interacting
Therapy Non-responder Required Intervention 43 Male 10/2/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 127 lb 10/23/2006 Other Health Professional Japan
Primary
Concomitant
Bronchospasm Life Threatening 1/13/2006 17 Female 10/18/2006 Japan
Primary
Concomitant
Acute Myocardial Infarction Other Serious 80 Male 10/30/2006 Japan
Primary
Concomitant
Urticaria Generalised Life Threatening 10/13/2006 26 Female 10/24/2006 Finland
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 70 Male 11/3/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/3/2006
Primary
Secondary
Concomitant
Movement Disorder Disability 88 Female 141 lb 11/7/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Postoperative Fever Other Serious 3/1/2005 71 Male 137 lb 11/1/2006 Physician Japan
Primary
Concomitant
Acute Myocardial Infarction Other Serious 80 Male 11/8/2006 Japan
Primary
Concomitant
Tracheomalacia Other Serious 66 Female 106 lb 11/8/2006
Primary
Secondary
Acute Myocardial Infarction Other Serious 80 Male 11/8/2006 Japan
Primary
Concomitant
Tachycardia Other Serious 8/24/2006 58 Male 165 lb 11/9/2006 Consumer United Kingdom
Primary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 11/14/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypoxia Life Threatening 75 Male 11/16/2006 Japan
Primary
Concomitant
Anaphylactoid Reaction 32 Female 11/7/2006 Other Health Professional Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 84 Female 11/17/2006 Japan
Primary
Secondary
Concomitant
Respiratory Tract Haemorrhage Life Threatening 75 Male 11/20/2006 Japan
Primary
Concomitant
Anaphylactic Shock 73 Female 11/9/2006 Physician Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 84 Female 11/21/2006 Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 55 Female 121 lb 11/27/2006 Other Health Professional Japan
Primary
Concomitant
Respiratory Disorder Other Serious 28 Female 11/8/2006 Japan
Primary
Concomitant
Spinal Column Stenosis Disability 88 Female 141 lb 11/28/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Procedural Complication 32 Female 11/15/2006 Japan
Primary
Concomitant
Tracheomalacia Other Serious 66 Female 106 lb 11/17/2006 Physician Japan
Primary
Secondary
Hypoxia Life Threatening 6/3/2006 Male 11/30/2006 Japan
Primary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 94 lb 12/4/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 3/1/2005 71 Male 137 lb 11/22/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/5/2006 Female 12/6/2006 Japan
Primary
Concomitant
Metabolic Acidosis Hospitalization 1/1/2006 14 Male 12/6/2006 United Kingdom
Primary
Secondary
Concomitant
Urticaria Other Serious 5/2/2006 32 Female 12/7/2006 Physician Japan
Primary
Secondary
Concomitant
Erythema Life Threatening 5/2/2006 32 Female 11/29/2006 Japan
Primary
Secondary
Concomitant
Blood Pressure Systolic Decreased Life Threatening 5/2/2006 32 Female 11/24/2006 Japan
Primary
Concomitant
Hepatotoxicity Hospitalization 11/9/2006 14 Male 90 lb 12/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myocardial Infarction Life Threatening 4/22/2006 Male 12/18/2006 Japan
Primary
Concomitant
Hepatotoxicity Hospitalization 11/9/2006 14 Male 90 lb 12/8/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 8/29/2005 81 Male 12/12/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 94 lb 12/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 0 Female 4 lb 1/8/2007 France
Primary
Secondary
Concomitant
Hypertension Life Threatening 3 Male 30 lb 1/8/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 28 Female 12/28/2006 Other Health Professional Japan
Primary
Concomitant
Supraventricular Extrasystoles Other Serious 79 Female 110 lb 1/17/2007 Physician United States
Primary
Concomitant
Interacting
Surgery Other Serious 69 Female 1/23/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/15/2007 92 Male 1/26/2007 Physician Japan
Primary
Concomitant
Drug Hypersensitivity Life Threatening 11/7/2006 26 Female 1/24/2007 Japan
Primary
Concomitant
Pulmonary Oedema Death 45 Female 2/1/2007 Physician Lebanon
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Life Threatening 11/7/2006 26 Female 1/26/2007 Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 45 Female 2/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sinus Arrest Hospitalization 5/25/2006 Male 2/9/2007 Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 21 Female 2/16/2007 Physician United Kingdom
Primary
Concomitant
Metabolic Acidosis Other Serious 32 Female 2/16/2007 Physician United Kingdom
Primary
Concomitant
Prothrombin Time Required Intervention 12/7/2005 56 Male 97 lb 2/14/2007 Physician Japan
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 5/25/2006 Male 97 lb 2/22/2007 Japan
Primary
Secondary
Concomitant
Ventricular Hypokinesia Death 45 Female 2/20/2007 Physician Lebanon
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 12/5/2006 66 Female 143 lb 2/28/2007 Physician France
Primary
Concomitant
Pulmonary Embolism Other Serious 7/5/2006 Female 3/9/2007 Japan
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 3/26/2007
Primary
Secondary
Concomitant
Hot Flush Other Serious 12/28/2005 24 Male 132 lb 4/2/2007 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Other Serious 5/1/2006 69 Male 4/4/2007 Other Health Professional Japan
Primary
Secondary
Laryngeal Oedema Life Threatening 3/26/2007 51 Female 4/6/2007 Japan
Primary
Secondary
Concomitant
Laryngeal Oedema Life Threatening 3/26/2007 51 Female 4/11/2007 Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 5/1/2006 69 Male 4/20/2007 Other Health Professional Japan
Primary
Secondary
Ventricular Fibrillation Other Serious 12/5/2006 66 Female 143 lb 4/30/2007 Other Health Professional France
Primary
Concomitant
Laryngeal Oedema Life Threatening 3/26/2007 51 Female 4/23/2007 Japan
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 78 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Other Serious 78 Female 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Post Procedural Complication Hospitalization 73 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 12 Male 5/15/2007 Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 12 Male 5/24/2007 Japan
Primary
Concomitant
Vitamin K Deficiency Hospitalization 75 Male 115 lb 5/23/2007 Japan
Primary
Concomitant
Tongue Oedema Required Intervention 51 Female 139 lb 2/22/2007 Physician United States
Primary
Concomitant
Urticaria Life Threatening 10/13/2006 26 Female 5/24/2007 Finland
Primary
Concomitant
Dystonia Other Serious 34 Female 6/6/2007 Australia
Primary
Secondary
Interacting
Dystonia Other Serious 34 Female 6/7/2007 Australia
Primary
Secondary
Interacting
Thrombocytopenia Death 7/17/2006 5 Female 44 lb 6/10/2007 Pharmacist United States
Primary
Secondary
Concomitant

Drug Data