Propofol combined with Remifentanil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 1/27/2005 71 Female 176 lb 3/2/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Electrocardiogram Qrs Complex Abnormal Other Serious 2/2/2006 58 Male 209 lb 3/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 3/7/2006 Female 3/30/2006 Physician Germany
Primary
Concomitant
Grand Mal Convulsion Other Serious 3/7/2006 Female 4/28/2006 Physician Germany
Primary
Concomitant
Vomiting Other Serious 65 Male 6/20/2006 United Kingdom
Primary
Concomitant
Vomiting Life Threatening 7/22/2005 65 Male 176 lb 8/4/2006 United Kingdom
Primary
Concomitant
Grand Mal Convulsion Other Serious 3/7/2006 Female 8/10/2006 Physician Germany
Primary
Concomitant
Neuromuscular Block Prolonged Hospitalization 4/24/2006 32 Female 8/11/2006 South Africa
Primary
Concomitant
Respiratory Distress Other Serious 8/28/2005 16 Male 8/26/2006 Physician Canada
Primary
Concomitant
Procedural Complication Other Serious Male 9/29/2006
Primary
Concomitant
Myocardial Ischaemia Other Serious Male 9/29/2006
Primary
Concomitant
Anaphylactic Reaction Life Threatening 9/14/2006 43 Male 10/18/2006 Norway
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/6/2006
Primary
Concomitant
Pulmonary Hypertension Other Serious 11/6/2006
Primary
Concomitant
Lung Disorder Other Serious 11/6/2006
Primary
Concomitant
Locked-in Syndrome Hospitalization 7/15/2006 53 Female 121 lb 11/21/2006 Consumer United Kingdom
Primary
Concomitant
Haemoptysis Hospitalization 12/4/2006 48 Female 12/13/2006 Physician Germany
Primary
Concomitant
Haemorrhage Hospitalization 12/4/2006 48 Female 1/8/2007 Germany
Primary
Concomitant
Haemorrhage Hospitalization 12/4/2006 48 Female 2/2/2007 Germany
Primary
Concomitant
Drug Interaction Hospitalization 1/27/1999 83 Female 154 lb 2/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Metabolic Acidosis Other Serious 32 Female 2/16/2007 Physician United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 9/25/2006 54 Female 2/23/2007 Consumer France
Primary
Concomitant
Vomiting Disability 9/21/2006 76 Female 134 lb 3/15/2007 United Kingdom
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Life Threatening 10/24/2005 Male 165 lb 4/5/2007 Physician
Primary
Secondary
Concomitant
Vomiting Other Serious 2/22/2007 54 Male 249 lb 4/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hot Flush Other Serious 3/29/2007 72 Male 4/16/2007 Consumer Japan
Primary
Concomitant
Vomiting Required Intervention 2/22/2007 54 Male 4/9/2007 United Kingdom
Primary
Concomitant
Vomiting Other Serious 2/22/2007 54 Male 249 lb 4/18/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting 2/22/2007 54 Male 4/10/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 2/22/2007 54 Male 249 lb 4/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 76 Male 4/25/2007 Belgium
Primary
Secondary
Hot Flush Other Serious 3/29/2007 72 Male 119 lb 4/30/2007 Consumer Japan
Primary
Secondary
Concomitant
Hot Flush Other Serious 3/29/2007 72 Male 119 lb 5/3/2007 Consumer Japan
Primary
Concomitant
Hot Flush Other Serious 3/29/2007 72 Male 119 lb 5/22/2007 Consumer Japan
Primary
Concomitant
Renal Failure Acute Other Serious 35 Female 5/23/2007 Other Health Professional Greece
Primary
Secondary
Concomitant
Hyperaesthesia Hospitalization 62 Male 159 lb 5/24/2007 Belgium
Primary
Concomitant
Wound Infection Bacterial Other Serious 26 Female 7/12/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 7/16/2007 45 Female 146 lb 8/13/2007 Physician United Kingdom
Primary
Concomitant
Cerebral Haematoma Death 7/18/2007 Male 8/31/2007 Other Health Professional France
Primary
Secondary
Concomitant
Acute Coronary Syndrome Other Serious 71 Male 174 lb 9/19/2007 Brazil
Primary
Concomitant
Sedation Other Serious 62 Male 9/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Urticaria Life Threatening 8/2/2007 69 Male 10/2/2007 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria Life Threatening 8/2/2007 69 Male 10/12/2007 Other Health Professional France
Primary
Secondary
Concomitant
Sedation Death 62 Male 10/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Bronchial Obstruction Other Serious 10/16/2007 52 Female 11/2/2007 Physician Norway
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 11/9/2007 Physician New Zealand
Primary
Concomitant
Rhabdomyolysis Life Threatening 1 Male 9 lb 11/15/2007 United States
Primary
Secondary
Concomitant
Respiratory Depression Life Threatening 53 Female 128 lb 11/19/2007
Primary
Secondary
Concomitant
Myocardial Ischaemia Life Threatening 45 Male 214 lb 12/5/2007 Japan
Primary
Secondary
Concomitant
Opisthotonus Other Serious 11/1/2006 20 Female 117 lb 12/7/2007 Other Health Professional China
Primary
Concomitant
Interacting
Circulatory Collapse Life Threatening 11/20/2007 53 Female 12/11/2007 Physician Norway
Primary
Secondary
Peripheral Coldness Hospitalization 11/2/2007 27 Male 12/18/2007 Other Health Professional Norway
Primary
Concomitant
Loss Of Consciousness Hospitalization 10/29/2007 22 Male 12/19/2007 Other Health Professional Norway
Primary
Concomitant
Hypotension Other Serious 71 Male 174 lb 12/21/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 4/16/2007 Male 1/3/2008 Other Health Professional France
Primary
Secondary
Concomitant
Peripheral Coldness Hospitalization 11/2/2007 27 Male 1/14/2008 Other Health Professional Norway
Primary
Concomitant
Respiratory Depression Other Serious 53 Female 128 lb 1/18/2008 New Zealand
Primary
Concomitant
Pain Other Serious 11/30/2007 3 Male 31 lb 1/28/2008 Pharmacist United Kingdom
Primary
Concomitant
Ill-defined Disorder Other Serious 11/30/2007 4 Male 35 lb 1/28/2008 Pharmacist United Kingdom
Primary
Concomitant
Respiratory Arrest Life Threatening 74 Female 1/28/2008 United Kingdom
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 4/16/2007 Male 1/30/2008 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Death 76 Female 104 lb 2/11/2008 Physician New Zealand
Primary
Concomitant
Hypersensitivity Other Serious Female 2/19/2008
Primary
Secondary
Concomitant
Hypersensitivity Other Serious Female 2/19/2008
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 41 Male 2/22/2008 Other Health Professional Netherlands
Primary
Concomitant
Anaphylactic Reaction Other Serious 65 Male 2/22/2008 Other Health Professional Netherlands
Primary
Concomitant
Vomiting Other Serious 7/22/2005 65 Male 176 lb 3/1/2008 United Kingdom
Primary
Concomitant
Serotonin Syndrome Hospitalization 65 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Lactic Acid Increased Other Serious 66 Male 146 lb 3/17/2008 Other Health Professional France
Primary
Concomitant
Vomiting Hospitalization 65 Male 3/13/2008 United Kingdom
Primary
Secondary
Concomitant
Rash Life Threatening 1/19/2008 46 Female 187 lb 4/14/2008 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious 46 Female 207 lb 4/21/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/12/2008 46 Male 5/8/2008 Pharmacist United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 7/16/2007 46 Female 146 lb 5/20/2008 Physician United Kingdom
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 8 Male 60 lb 5/22/2008
Primary
Secondary
Concomitant
Hyperaesthesia Other Serious 46 Female 139 lb 5/30/2008 Spain
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 1/1/2008 8 Male 60 lb 6/26/2008 Other Health Professional Germany
Primary
Concomitant
Anaphylactic Shock Hospitalization 11/20/2007 Female 7/2/2008 Other Health Professional France
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 5/29/2008 42 Male 7/22/2008 Other Health Professional France
Primary
Secondary
Vomiting Other Serious 7/22/2008 65 Male 176 lb 8/13/2008 United Kingdom
Primary
Concomitant
Interacting
Anaphylactic Shock Hospitalization 11/20/2007 Female 8/19/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tachycardia Life Threatening 8/7/2008 50 Male 9/4/2008 Consumer France
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 8/23/2008 89 Male 132 lb 9/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Arrest Life Threatening 7/8/2004 52 Female 9/10/2008 New Zealand
Primary
Concomitant
Coagulopathy Other Serious Female 9/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Contractions Involuntary Other Serious 19 Male 10/15/2008 Japan
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psychotic Behaviour 8/25/2008 24 Female 10/13/2008 Belgium
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 1 Male 10/15/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 47 Female 11/5/2008 Japan
Primary
Secondary
Concomitant
Muscle Contractions Involuntary Other Serious 19 Male 152 lb 11/14/2008 Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 47 Female 11/17/2008 Japan
Primary
Secondary
Concomitant
Vocal Cord Disorder Other Serious 11/18/2008 Japan
Primary
Concomitant
Vocal Cord Disorder Other Serious 11/18/2008 Japan
Primary
Concomitant
Vocal Cord Disorder Other Serious 11/18/2008 Japan
Primary
Concomitant
Staring Hospitalization 44 Female 11/21/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Drug Interaction Other Serious 77 Female 11/25/2008 Germany
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sluggishness Other Serious 44 Female 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vocal Cord Disorder Other Serious 57 Female 143 lb 12/10/2008 Japan
Primary
Concomitant
Vocal Cord Disorder Other Serious 43 Female 126 lb 12/10/2008 Japan
Primary
Concomitant
Vocal Cord Disorder Other Serious 54 Female 123 lb 12/10/2008 Japan
Primary
Concomitant
Serotonin Syndrome Other Serious 44 Female 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diabetes Insipidus Other Serious 13 Male 12/11/2008 United States
Primary
Secondary
Serotonin Syndrome Hospitalization 44 Female 12/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 44 Female 12/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 44 Female 12/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lactic Acidosis Other Serious 6/13/2006 43 Female 1/6/2009 Other Health Professional Chile
Primary
Concomitant
Staring Life Threatening 44 Female 1/12/2009
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 12/29/2008 Male 1/15/2009 Pharmacist United Kingdom
Primary
Concomitant
Tachycardia Other Serious 1/10/2006 64 Female 1/23/2009 Physician France
Primary
Secondary
Serotonin Syndrome Other Serious 44 Female 1/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 1/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 6/11/2008 Female 1/26/2009 Physician France
Primary
Secondary
Concomitant
Staring Life Threatening 44 Female 1/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 11/3/2008 44 Female 1/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Life Threatening 44 Female 1/27/2009 United Kingdom
Primary
Secondary
Concomitant
Staring Life Threatening 44 Female 2/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staring Life Threatening 44 Female 2/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 44 Female 2/18/2009
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 2/18/2009
Primary
Secondary
Concomitant
Wound Infection Hospitalization 2/18/2009
Primary
Secondary
Concomitant
Wheezing Life Threatening 2/2/2009 31 Female 2/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Life Threatening 2/2/2009 31 Female 2/19/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 5 2/25/2009 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 2/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 44 Female 2/26/2009
Primary
Secondary
Concomitant
Hypotonia Other Serious 3 2/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 5/29/2008 42 Male 3/2/2009 Other Health Professional France
Primary
Secondary
White Blood Cell Count Increased Other Serious 44 Female 3/10/2009
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 3/9/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 3/11/2009
Primary
Secondary
Concomitant
Hypotonia Other Serious 3 NotSpecified 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 2/13/2009 Female 49 lb 3/25/2009 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 3/20/2009 United Kingdom
Primary
Secondary
Concomitant
Hypotonia Other Serious 3 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psychotic Behaviour 8/25/2008 24 Female 4/6/2009 Belgium
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 60 Male 4/13/2009
Primary
Secondary
Metabolic Alkalosis Other Serious 64 Female 117 lb 4/14/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 4/10/2009 Male 170 lb 4/13/2009 United States
Primary
Concomitant
Metabolic Alkalosis Other Serious 64 Female 117 lb 5/27/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 3/23/2007 60 Male 7/23/2009
Primary
Secondary
Unresponsive To Stimuli Required Intervention 66 Male 154 lb 7/30/2009 Physician Germany
Primary
Concomitant
Premature Recovery From Anaesthesia Other Serious 5/30/2008 51 Female 8/19/2009 Physician United Kingdom
Primary
Concomitant
Serotonin Syndrome Hospitalization 65 Male 8/26/2009 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 44 Female 8/28/2009 United Kingdom
Primary
Concomitant

Drug Data