Promethazine combined with Vitamin B-12

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vitamin B12 Deficiency Hospitalization 1/23/2006 67 Male 169 lb 3/7/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 5/14/2006 49 Female 175 lb 6/22/2006 Physician United States
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 5/19/2006 52 Female 141 lb 8/3/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 8/17/2006 Female 8/28/2006 Pharmacist United States
Primary
Concomitant
Activated Partial Thromboplastin Time Prolonged Other Serious 8/17/2006 Female 9/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/19/2006 52 Female 141 lb 9/7/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 7/3/2006 50 Female 150 lb 10/26/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 7/3/2006 50 Female 150 lb 10/26/2006 Physician United States
Primary
Concomitant
Laboratory Test Interference Other Serious 8/17/2006 Female 11/7/2006 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 64 Female 178 lb 4/18/2007 Physician United States
Primary
Concomitant
Rectocele Repair Hospitalization 12/11/2006 50 Female 5/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 4/5/2007 61 Female 97 lb 6/14/2007 Other Health Professional United States
Primary
Concomitant
Resorption Bone Increased Other Serious 1/1/1999 Female 8/10/2007 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 4/5/2007 61 Female 97 lb 11/15/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 128 lb 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Interacting
Hypoglycaemia Hospitalization 3/1/2008 Female 177 lb 3/11/2008 United States
Primary
Concomitant
Hypoglycaemia Hospitalization 3/1/2008 Female 177 lb 3/18/2008 United States
Primary
Concomitant
Hypomagnesaemia Hospitalization 5/10/2008 Male 110 lb 5/31/2008 Physician United States
Primary
Concomitant
Anaphylactic Reaction Life Threatening 7/4/2008 Male 132 lb 7/10/2008 Physician China
Primary
Concomitant
Tremor Other Serious 1/1/2007 Female 280 lb 7/22/2008 Consumer United States
Primary
Concomitant
Anaphylactic Reaction Life Threatening 7/4/2008 Male 132 lb 7/28/2008 Physician China
Primary
Concomitant
Vomiting Hospitalization 3/25/2008 Female 159 lb 9/22/2008 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2008 42 Female 190 lb 10/1/2008 United States
Primary
Concomitant
Vomiting Hospitalization 3/25/2008 Female 159 lb 10/14/2008 United States
Primary
Concomitant
Scrotal Gangrene Hospitalization 10/10/2008 Male 166 lb 10/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Scrotal Gangrene Hospitalization 10/10/2008 Male 166 lb 10/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Scrotal Gangrene Hospitalization 10/10/2008 Male 166 lb 11/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Proctalgia Hospitalization 10/10/2008 Male 166 lb 11/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Proctalgia Hospitalization 10/10/2008 Male 166 lb 12/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Cancer Metastatic Death 1/16/2009 Male 120 lb 3/18/2009 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 3/19/2009 Female 201 lb 4/30/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 38 Female 282 lb 5/20/2009 United States
Primary
Secondary
Concomitant
Dysplastic Naevus Syndrome Other Serious Male 194 lb 6/24/2009 Physician United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/1/2009 Male 194 lb 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2003 35 Female 291 lb 8/3/2009 United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 3/19/2009 Female 201 lb 8/6/2009 United States
Primary
Concomitant
Wound Infection Other Serious 3/1/2008 68 Female 205 lb 8/20/2009 Lawyer United States
Primary
Concomitant
Flushing Female 8/22/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 9/7/2008 33 Male 236 lb 9/25/2009 Consumer United States
Primary
Secondary
Concomitant
Mobility Decreased Hospitalization 6/19/2009 Female 188 lb 9/29/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 148 lb 11/3/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 11/4/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2009 66 Male 157 lb 11/17/2009 Consumer United States
Primary
Secondary
Concomitant
Thalassaemia Other Serious 76 Female 11/17/2009 United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 11/24/2009 Consumer United States
Primary
Concomitant
Tremor Other Serious 1/1/2007 Female 280 lb 12/1/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 12/23/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 73 Female 1/11/2010 Lawyer United States
Primary
Concomitant
Surgery Hospitalization 73 Female 1/21/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 74 Female 164 lb 1/20/2010 United States
Primary
Concomitant
Surgery Hospitalization 73 Female 2/9/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2010 Male 3/18/2010 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2010 Male 3/22/2010 Consumer United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Death 3/1/2010 Female 128 lb 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Death Death Male 4/2/2010 Consumer United States
Primary
Concomitant
Haemorrhagic Stroke Death 3/1/2010 62 Female 128 lb 4/6/2010 Physician United States
Primary
Secondary
Concomitant
Fibromyalgia Other Serious Female 110 lb 4/7/2010 Physician
Primary
Secondary
Concomitant
Viral Infection Hospitalization 73 Female 4/8/2010 Lawyer United States
Primary
Concomitant
Fibromyalgia Other Serious 2/1/2009 64 Female 110 lb 4/21/2010 Physician
Primary
Secondary
Concomitant
Wheezing Death Male 4/21/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2010 58 Male 4/29/2010 Consumer United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Death 3/1/2010 62 Female 128 lb 4/30/2010 Physician United States
Primary
Secondary
Concomitant
Intentional Drug Misuse Hospitalization 3/7/2010 26 Male 5/3/2010 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 2/1/2008 68 Female 205 lb 5/14/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2010 58 Male 5/17/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 2/1/2008 68 Female 205 lb 6/1/2010 United States
Primary
Concomitant
Seborrhoeic Dermatitis Other Serious 2/1/2009 64 Female 110 lb 6/15/2010 Physician
Primary
Secondary
Concomitant
Vaginal Ulceration Other Serious 2/1/2010 69 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 38 Female 138 lb 7/1/2010 United States
Primary
Concomitant
Pleural Effusion Other Serious 1/29/2010 82 Male 154 lb 7/7/2010 Consumer United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 3/19/2009 62 Female 201 lb 7/8/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2010 58 Male 7/16/2010 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 5/1/2010 66 Male 220 lb 7/26/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 35 Female 8/5/2010 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 5/1/2010 66 Male 220 lb 8/10/2010 Consumer United States
Primary
Concomitant
No Adverse Event Male 8/12/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2010 58 Male 8/18/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/17/2010 39 Female 9/10/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 52 Female 148 lb 9/16/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 35 Female 127 lb 9/21/2010 Consumer United States
Primary
Concomitant
Fatigue Hospitalization 9/7/2010 66 Male 183 lb 9/20/2010 Physician United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 5/1/2010 66 Male 227 lb 9/22/2010 Physician United States
Primary
Concomitant
Fatigue Hospitalization 9/7/2010 66 Male 183 lb 9/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 53 Female 10/7/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2010 58 Male 10/8/2010 Consumer United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 8/1/2010 49 Female 9/28/2010 Consumer United States
Primary
Concomitant
Heart Rate Increased Other Serious 9/1/2010 44 Female 216 lb 10/14/2010 Consumer United States
Primary
Concomitant
Hepatic Steatosis Other Serious 8/1/2010 59 Female 218 lb 10/22/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 10/20/2010 United States
Primary
Concomitant
Fatigue Hospitalization 9/7/2010 66 Male 183 lb 11/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 10/7/2010 47 Female 140 lb 11/4/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased 10/1/2009 90 Female 11/17/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/19/2009 74 Female 172 lb 11/22/2010 Physician United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 8/1/2010 58 Female 160 lb 11/24/2010 Physician United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 9/7/2010 66 Male 183 lb 11/29/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/19/2009 74 Female 172 lb 12/2/2010 Physician United States
Primary
Concomitant
Anaemia Hospitalization 9/7/2010 66 Male 183 lb 12/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 10/1/2009 90 Female 12/8/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 52 Female 148 lb 11/3/2009 Consumer United States
Primary
Secondary
Concomitant
Obstruction Other Serious 1/1/2010 58 Male 166 lb 1/10/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 9/1/2010 44 Female 220 lb 1/18/2011 Consumer United States
Primary
Secondary
Concomitant
Blister 6/23/2010 43 Female 1/29/2011 Consumer United States
Primary
Concomitant
Hangover 11/29/2010 38 Female 1/30/2011 Consumer United States
Primary
Concomitant
Chest Pain 1/1/2009 40 Female 170 lb 1/30/2011 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 12/1/2010 72 Male 2/23/2011 United States
Primary
Concomitant
Gingival Bleeding Other Serious 12/1/2010 88 Female 3/1/2011 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 3/3/2011 54 Female 3/21/2011 Consumer United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 1/1/2008 39 Male 235 lb 3/22/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 3/3/2011 54 Female 3/23/2011 United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 10/11/2010 72 Male 183 lb 3/25/2011 Consumer United States
Primary
Secondary
Concomitant
Arthralgia Hospitalization 1/1/2008 39 Male 235 lb 4/6/2011 Consumer United States
Primary
Concomitant
Gait Disturbance Other Serious 3/3/2011 54 Female 4/11/2011 Consumer United States
Primary
Secondary
Concomitant
Cholecystectomy Other Serious 7/1/2008 21 Female 104 lb 4/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Migraine Other Serious 3/3/2011 54 Female 4/20/2011 United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death Male 161 lb 4/20/2011 Consumer United States
Primary
Concomitant
Biliary Dyskinesia Other Serious 7/1/2008 21 Female 104 lb 4/26/2011 Consumer United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 3/19/2009 62 Female 201 lb 5/13/2011 Physician United States
Primary
Concomitant
Electroencephalogram Abnormal Other Serious 11/1/2010 48 Female 5/18/2011 Consumer United States
Primary
Concomitant
Large Intestine Perforation Hospitalization 7/25/2010 67 Male 168 lb 5/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cyanosis Other Serious 3/3/2011 54 Female 5/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 5/12/2011 68 Female 130 lb 5/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 7/25/2010 67 Male 165 lb 5/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Distension Death 5/12/2011 68 Female 130 lb 6/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 5/12/2011 68 Female 130 lb 6/29/2011 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/1/2011 34 Female 7/8/2011 Physician United States
Primary
Concomitant
Blood Albumin Decreased Required Intervention 1/1/2010 61 Female 145 lb 6/29/2011 Consumer United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Required Intervention 1/1/2010 61 Female 145 lb 7/19/2011 Consumer United States
Primary
Secondary
Concomitant
Constipation Hospitalization 2/1/2006 85 Male 7/29/2011 Other Health Professional United States
Primary
Concomitant
Headache Other Serious Female 8/8/2011 Consumer United States
Primary
Concomitant
Blood Calcium Decreased Required Intervention 1/1/2010 61 Female 145 lb 8/11/2011 Consumer United States
Primary
Secondary
Concomitant
Off Label Use Disability 7/2/2009 41 Female 8/19/2011 United States
Primary
Secondary
Concomitant
Death Death 7/29/2011 52 Female 8/30/2011 Consumer United States
Primary
Secondary
Death Death 7/29/2011 52 Female 8/30/2011 Consumer United States
Primary
Secondary
Headache Other Serious Female 110 lb 9/6/2011 Physician United States
Primary
Concomitant
Aggression 10/1/2009 90 Female 9/22/2011 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected Hospitalization 3/1/2011 34 Female 9/22/2011 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 11/8/2010 29 Female 190 lb 9/27/2011 Other Health Professional United States
Primary
Concomitant
Mobility Decreased Hospitalization 6/19/2009 77 Female 188 lb 9/27/2011 Consumer United States
Primary
Secondary
Concomitant
Application Site Vesicles Other Serious 1/1/2006 44 Female 160 lb 10/7/2011 Consumer United States
Primary
Concomitant
Joint Injury Other Serious 1/1/2006 44 Female 160 lb 10/10/2011 Consumer United States
Primary
Concomitant
Gastric Disorder Hospitalization 2/1/2006 25 Female 249 lb 10/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2010 59 Female 10/12/2011 Consumer United States
Primary
Concomitant
Electroencephalogram Abnormal Other Serious 11/1/2010 48 Female 10/14/2011 Other Health Professional United States
Primary
Concomitant
Breast Cancer Metastatic Death 7/29/2011 52 Female 10/14/2011 Consumer United States
Primary
Secondary
Breast Cancer Metastatic Death 7/29/2011 52 Female 10/14/2011 Physician United States
Primary
Secondary
Depression Other Serious 1/1/2006 44 Female 160 lb 10/20/2011 Consumer United States
Primary
Concomitant
Cholelithiasis Hospitalization 2/1/2006 25 Female 249 lb 10/12/2011 Consumer United States
Primary
Secondary
Concomitant
Emotional Distress Hospitalization 2/1/2006 25 Female 249 lb 10/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fall Other Serious 8/1/2010 63 Female 10/26/2011 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 4/1/2011 50 Female 142 lb 9/9/2011 Consumer United States
Primary
Secondary
Concomitant

Drug Data