Pradaxa combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Throat Tightness 11/1/2010 81 Female 12/16/2010 Consumer
Primary
Concomitant
Hyperchlorhydria 12/2/2010 67 Male 12/22/2010 Consumer
Primary
Concomitant
Malaise Hospitalization 12/7/2010 62 Female 12/23/2010 Consumer
Primary
Concomitant
Pruritus 11/22/2010 85 Female 12/30/2010 Consumer
Primary
Concomitant
Musculoskeletal Discomfort 12/16/2010 57 Female 1/5/2011 Consumer
Primary
Concomitant
Contusion 12/1/2010 63 Male 1/6/2011 Consumer
Primary
Concomitant
Chest Pain 12/15/2010 78 Male 1/10/2011 Consumer
Primary
Concomitant
Headache 12/1/2010 72 Female 1/11/2011 Consumer
Primary
Concomitant
Cough 12/26/2010 Male 1/12/2011 Consumer
Primary
Concomitant
Dizziness 12/8/2010 80 Female 1/13/2011 Consumer
Primary
Concomitant
Abdominal Distension 12/3/2010 67 Male 1/13/2011 Consumer
Primary
Concomitant
Weight Increased 12/1/2010 71 Male 269 lb 1/14/2011 Consumer
Primary
Concomitant
Pain In Extremity 12/17/2010 57 Female 1/19/2011 Consumer
Primary
Concomitant
Creatinine Renal Clearance 11/29/2010 Male 1/20/2011 Other Health Professional
Primary
Concomitant
Dizziness Hospitalization 12/15/2010 62 Female 1/31/2011 Consumer
Primary
Concomitant
Thirst 1/8/2011 70 Male 2/16/2011 Pharmacist United States
Primary
Concomitant
Laceration 12/3/2010 67 Male 2/24/2011 Consumer United States
Primary
Concomitant
Faeces Discoloured 12/20/2010 76 Male 2/26/2011 Consumer United States
Primary
Concomitant
Activities Of Daily Living Impaired 12/8/2010 80 Female 2/27/2011 Consumer United States
Primary
Concomitant
Eructation 1/22/2011 75 Male 2/28/2011 Consumer United States
Primary
Concomitant
Blood Potassium Increased 1/28/2011 82 Female 2/28/2011 Other Health Professional United States
Primary
Concomitant
Flatulence 1/1/2011 80 Male 2/28/2011 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization 1/8/2011 78 Male 223 lb 3/3/2011 Physician United States
Primary
Concomitant
Ankle Fracture Hospitalization 12/17/2010 84 Female 216 lb 2/23/2011 Pharmacist United States
Primary
Secondary
Concomitant
Foreign Body 12/24/2010 72 Male 3/14/2011 Consumer United States
Primary
Concomitant
Asthenia 1/1/2011 80 Male 3/14/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Upper 11/1/2010 65 Male 3/16/2011 Consumer United States
Primary
Concomitant
Diarrhoea 1/1/2011 71 Female 3/16/2011 Consumer United States
Primary
Concomitant
Throat Irritation 2/17/2011 64 Male 3/16/2011 Consumer United States
Primary
Concomitant
Flatulence 2/3/2011 81 Female 3/16/2011 Consumer United States
Primary
Concomitant
Nervousness 2/15/2011 68 Female 3/16/2011 Consumer United States
Primary
Concomitant
Insomnia 12/20/2010 66 Female 3/18/2011 Consumer United States
Primary
Concomitant
Formication 2/16/2011 Male 3/21/2011 Consumer United States
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 3/15/2011 77 Male 194 lb 3/21/2011 Pharmacist United States
Primary
Concomitant
Cystitis 2/1/2011 86 Male 3/25/2011 Consumer United States
Primary
Secondary
Creatinine Renal Clearance 11/29/2010 Male 3/25/2011 Other Health Professional United States
Primary
Concomitant
Malaise Female 3/29/2011 Consumer United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Male 3/29/2011 Consumer United States
Primary
Concomitant
Anal Haemorrhage 2/1/2011 79 Male 3/30/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Upper 2/1/2011 86 Female 4/1/2011 Consumer United States
Primary
Concomitant
Headache 3/7/2011 67 Male 4/1/2011 Consumer United States
Primary
Concomitant
Constipation 2/1/2011 86 Female 4/8/2011 Consumer United States
Primary
Concomitant
Eructation 3/8/2011 79 Female 4/12/2011 Consumer United States
Primary
Concomitant
Asthenia 3/16/2011 88 Female 4/14/2011 Consumer United States
Primary
Concomitant
Abdominal Discomfort 1/15/2011 67 Female 4/15/2011 Consumer United States
Primary
Concomitant
Nausea 2/1/2011 83 Male 4/19/2011 Consumer United States
Primary
Concomitant
Swelling Face 3/24/2011 77 Male 4/19/2011 Consumer United States
Primary
Concomitant
Decreased Appetite Hospitalization 3/8/2011 77 Female 4/19/2011 Consumer United States
Primary
Concomitant
Haematemesis Hospitalization 3/1/2011 46 Male 276 lb 4/21/2011 Physician United States
Primary
Concomitant
Frequent Bowel Movements 1/28/2011 75 Female 4/21/2011 Consumer United States
Primary
Concomitant
Throat Irritation 1/1/2011 77 Female 4/22/2011 Consumer United States
Primary
Secondary
Concomitant
Odynophagia 2/28/2011 79 Female 4/22/2011 Consumer United States
Primary
Concomitant
Blood Potassium Decreased 11/1/2010 65 Male 4/22/2011 Consumer United States
Primary
Secondary
Concomitant
Burning Sensation 1/24/2011 86 Female 4/24/2011 Consumer United States
Primary
Concomitant
Asthenia 2/1/2011 86 Male 4/25/2011 Consumer United States
Primary
Secondary
Headache 4/12/2011 70 Male 4/25/2011 Consumer United States
Primary
Concomitant
Gait Disturbance Hospitalization 4/1/2011 82 Female 4/29/2011 Pharmacist United States
Primary
Concomitant
Oropharyngeal Pain 1/1/2011 79 Male 5/6/2011 Consumer United States
Primary
Concomitant
Headache 3/7/2011 67 Male 5/6/2011 Consumer United States
Primary
Concomitant
Drug Level Below Therapeutic 3/8/2011 51 Male 5/6/2011 Physician United States
Primary
Concomitant
Abdominal Discomfort 1/1/2011 80 Male 5/9/2011 Consumer United States
Primary
Concomitant
Gastrointestinal Pain 2/3/2011 81 Female 5/10/2011 Consumer United States
Primary
Concomitant
Malaise 1/12/2011 80 Female 5/10/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 1/1/2011 55 Male 208 lb 5/16/2011 Other Health Professional United States
Primary
Concomitant
Constipation 1/30/2011 71 Female 5/18/2011 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/10/2011 85 Female 82 lb 5/25/2011 Physician United States
Primary
Concomitant
Blood Glucose Increased 4/1/2011 70 Male 5/26/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Death 1/1/2010 74 Male 5/27/2011 Physician Canada
Primary
Concomitant
Joint Swelling 2/20/2011 74 Male 6/1/2011 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 5/5/2011 73 Male 126 lb 6/1/2011 Pharmacist Japan
Primary
Concomitant
Renal Impairment Other Serious 76 Male 6/2/2011 Pharmacist Japan
Primary
Concomitant
Anaemia Life Threatening 4/3/2011 83 Male 155 lb 6/2/2011 Physician United States
Primary
Concomitant
Polymyositis 69 Female 6/5/2011 Physician United States
Primary
Concomitant
Urinary Incontinence 1/12/2011 80 Female 6/7/2011 Physician United States
Primary
Concomitant
Abdominal Discomfort 5/6/2011 73 Male 126 lb 6/10/2011 Pharmacist Japan
Primary
Concomitant
Dizziness 5/24/2011 87 Male 6/13/2011 Consumer United States
Primary
Concomitant
Eye Disorder 4/12/2011 70 Male 6/14/2011 Consumer United States
Primary
Concomitant
Intentional Drug Misuse Male 197 lb 6/15/2011 Physician United States
Primary
Concomitant
Head Injury Hospitalization 4/1/2011 82 Female 126 lb 6/16/2011 Pharmacist United States
Primary
Concomitant
Renal Impairment Hospitalization 5/4/2011 76 Male 125 lb 6/22/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Distension 12/3/2010 67 Male 6/28/2011 Consumer United States
Primary
Secondary
Concomitant
Eructation Hospitalization 3/8/2011 77 Female 6/30/2011 Consumer United States
Primary
Concomitant
Epistaxis Other Serious 4/26/2011 87 Male 6/30/2011 Consumer United States
Primary
Concomitant
Capillary Fragility 6/1/2011 72 Male 7/1/2011 Consumer United States
Primary
Concomitant
Renal Cyst Other Serious 11/1/2010 65 Male 7/5/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Cancer Other Serious 4/26/2011 87 Male 7/18/2011 Physician United States
Primary
Concomitant
Malaise 1/12/2011 80 Female 7/18/2011 Physician United States
Primary
Concomitant
Cystitis 7/6/2011 74 Female 7/19/2011 Consumer United States
Primary
Concomitant
Gastrooesophageal Reflux Disease 1/15/2011 67 Female 7/19/2011 Consumer United States
Primary
Concomitant
Dizziness Hospitalization 4/1/2011 71 Male 7/22/2011 Consumer United States
Primary
Concomitant
Head Injury 12/3/2010 67 Male 7/22/2011 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization 4/25/2011 74 Male 244 lb 7/27/2011 Physician United States
Primary
Concomitant
Melaena Death 6/20/2011 75 Female 146 lb 7/28/2011 Physician United States
Primary
Concomitant
Confusional State 4/1/2011 61 Female 8/4/2011 Consumer United States
Primary
Concomitant
Faecal Volume Decreased 5/5/2011 68 Female 8/8/2011 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 5/19/2011 71 Female 8/9/2011 Physician Malaysia
Primary
Concomitant
Dyspepsia 7/17/2011 82 Female 8/10/2011 Consumer United States
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 7/27/2011 66 Female 315 lb 8/12/2011 Pharmacist United States
Primary
Concomitant
Somnolence 3/1/2011 64 Male 8/17/2011 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 6/21/2011 73 Male 8/17/2011 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased 4/12/2011 73 Female 8/19/2011 Physician United States
Primary
Concomitant
Back Pain Female 8/19/2011 Consumer United States
Primary
Concomitant
Nausea 8/1/2011 69 Male 8/23/2011 Consumer United States
Primary
Concomitant
Blood Glucose Fluctuation 6/1/2011 82 Female 8/23/2011 Consumer United States
Primary
Concomitant
Abdominal Discomfort 8/10/2011 86 Female 8/24/2011 Consumer United States
Primary
Concomitant
Atrial Thrombosis Other Serious 71 Male 256 lb 8/24/2011 Physician United States
Primary
Concomitant
Flatulence 8/12/2011 67 Male 8/30/2011 Consumer United States
Primary
Concomitant
Renal Disorder Other Serious 6/21/2011 73 Male 140 lb 8/31/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 8/16/2011 81 Female 157 lb 9/7/2011 Physician Australia
Primary
Concomitant
Bleeding Time Prolonged Death 7/17/2011 89 Female 126 lb 9/8/2011 Physician New Zealand
Primary
Concomitant
Drug Interaction 57 Female 9/8/2011 Consumer United States
Primary
Concomitant
Interacting
Aspartate Aminotransferase Increased Other Serious 9/5/2011 65 Female 9/12/2011 Pharmacist Japan
Primary
Concomitant
Somnolence 3/1/2011 64 Male 9/13/2011 Physician United States
Primary
Concomitant
Hallucination Hospitalization 7/28/2011 73 Male 190 lb 9/20/2011 Physician Australia
Primary
Secondary
Concomitant
Contusion 1/1/2011 88 Female 9/20/2011 Consumer United States
Primary
Concomitant
Increased Upper Airway Secretion 8/25/2011 79 Female 9/23/2011 Consumer United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 9/5/2011 65 Female 112 lb 9/26/2011 Pharmacist Japan
Primary
Concomitant
Melaena Hospitalization 9/5/2011 87 Female 110 lb 9/26/2011 Physician Denmark
Primary
Secondary
Concomitant
Musculoskeletal Pain 8/1/2011 87 Female 9/27/2011 Consumer United States
Primary
Concomitant
Gastritis Hospitalization 5/25/2011 70 Female 176 lb 9/28/2011 Pharmacist United States
Primary
Concomitant
Blister 6/1/2011 72 Female 9/29/2011 Consumer United States
Primary
Concomitant
Arthralgia 4/12/2011 73 Female 9/29/2011 Physician United States
Primary
Secondary
Concomitant
Insomnia 8/12/2011 67 Male 10/3/2011 Consumer United States
Primary
Concomitant
Melaena Hospitalization 9/5/2011 87 Female 110 lb 10/3/2011 Physician Denmark
Primary
Secondary
Concomitant
Contusion 8/1/2011 78 Female 10/4/2011 Consumer United States
Primary
Concomitant
Dizziness Hospitalization 3/1/2011 71 Male 10/5/2011 Consumer United States
Primary
Concomitant
Hot Flush 1/1/2011 74 Male 10/5/2011 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Life Threatening 9/30/2011 62 Male 220 lb 10/6/2011 Physician Germany
Primary
Concomitant
Erection Increased 8/1/2011 45 Male 10/6/2011 Consumer United States
Primary
Concomitant
Arthralgia 10/7/2011 Female 10/13/2011 Consumer United States
Primary
Concomitant
Dyspepsia 8/23/2011 86 Female 123 lb 10/14/2011 Physician New Zealand
Primary
Concomitant
Thrombocytopenia Hospitalization 4/8/2011 88 Male 10/14/2011 Physician United States
Primary
Concomitant
Alopecia 4/12/2011 73 Female 10/17/2011 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization Male 10/17/2011 Physician United States
Primary
Concomitant
Chest X-ray Abnormal 10/1/2011 83 Female 10/18/2011 Consumer United States
Primary
Concomitant
Contusion 10/5/2011 87 Female 10/19/2011 Consumer United States
Primary
Concomitant
Oesophageal Pain 10/1/2010 89 Male 10/20/2011 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization Female 10/21/2011 Pharmacist United States
Primary
Concomitant
Asthenia 5/1/2011 88 Female 10/24/2011 Consumer United States
Primary
Concomitant
Fall Hospitalization 7/17/2011 84 Female 10/26/2011 Physician Australia
Primary
Concomitant
Hot Flush 1/1/2011 74 Male 10/28/2011 Consumer United States
Primary
Concomitant
Ischaemic Stroke Life Threatening 10/21/2011 53 Male 302 lb 10/27/2011 Pharmacist United States
Primary
Concomitant
Creatinine Renal Clearance 11/29/2010 Male 11/1/2011 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/10/2011 85 Female 82 lb 11/3/2011 Physician United States
Primary
Concomitant
Malaise 7/5/2011 90 Female 11/4/2011 Pharmacist New Zealand
Primary
Concomitant
Death Death 7/17/2011 89 Female 126 lb 11/4/2011 Physician New Zealand
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/1/2011 68 Male 11/4/2011 Physician Norway
Primary
Concomitant
Acute Myocardial Infarction Hospitalization Female 11/4/2011 Other Health Professional United States
Primary
Concomitant
Fall Death 7/17/2011 89 Female 126 lb 11/7/2011 Physician New Zealand
Primary
Concomitant
Haemorrhage Disability 7/17/2011 89 Female 11/7/2011 Physician New Zealand
Primary
Concomitant

Drug Data