Phenobarbital combined with Phenytoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Haemodynamic Instability Required Intervention 9 Male 8/31/2006 Physician Belgium
Primary
Concomitant
Ventricular Tachycardia Death 2/15/2006 Male 235 lb United States
Primary
Concomitant
Convulsion Hospitalization 11/1/2006 79 Female 1/4/2007 Physician France
Primary
Concomitant
Convulsion Other Serious 11/1/2006 79 Female 1/12/2007 Other Health Professional France
Primary
Concomitant
Pneumonia Death 11/1/2008 81 Male 12/11/2008 Germany
Primary
Concomitant
Sepsis Hospitalization 3/8/1988 Male 165 lb 12/18/2008 Physician Canada
Primary
Secondary
Concomitant
Treatment Noncompliance Death 7/1/2005 39 Female 2/3/2009 Other Health Professional Japan
Primary
Concomitant
Chest Pain Hospitalization 2/4/2009 2/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 0 4/1/2009
Primary
Secondary
Spinal Disorder Other Serious 6/1/2005 Male 180 lb 4/9/2009 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Death 3 Male 4/15/2009 Consumer Turkey
Primary
Concomitant
Spinal Disorder Other Serious 6/1/2005 Male 180 lb 4/24/2009 Consumer United States
Primary
Secondary
Concomitant
Laceration Hospitalization 3/17/2009 72 Male 194 lb 4/27/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1 Female 5/1/2009 Physician Turkey
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/14/2009 Male 5/1/2009 Consumer Switzerland
Primary
Concomitant
Hepatomegaly Other Serious 13 Female 110 lb 5/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1 Female 5/15/2009 Physician Turkey
Primary
Secondary
Concomitant
Wheezing Other Serious 8/6/2001 25 Male 256 lb 5/21/2009 United States
Primary
Concomitant
Hepatomegaly Other Serious 13 Female 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Regurgitation Hospitalization 0 7/7/2009 France
Primary
Concomitant
Diabetic Retinopathy Other Serious 6/23/2003 31 Male 248 lb 7/14/2009 United States
Primary
Concomitant
Status Epilepticus Other Serious 6/25/2000 19 Female 8/3/2009 Physician Japan
Primary
Concomitant
Tracheal Stenosis Other Serious 7/8/2009 16 Male 8/12/2009 Physician Brazil
Primary
Concomitant
Status Epilepticus Other Serious 24 8/31/2009 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 7/16/2009 Female 110 lb 9/1/2009 Japan
Primary
Concomitant
Pneumonia Hospitalization 7/16/2009 Female 110 lb 9/3/2009 Japan
Primary
Concomitant
Pulmonary Fibrosis Other Serious 66 Male 9/8/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 24 9/4/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 66 Male 9/10/2009 Physician Japan
Primary
Concomitant
Incorrect Dose Administered 8/3/2007 Female 195 lb 9/11/2009 Consumer United States
Primary
Concomitant
Propofol Infusion Syndrome Death 37 Male 9/14/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 7/16/2009 Female 110 lb 9/15/2009 Japan
Primary
Concomitant
Spinal Disorder Other Serious 1/1/2005 Male 180 lb 9/21/2009 United States
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 24 9/22/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 66 Male 9/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tracheal Stenosis Other Serious 7/8/2009 16 Male 9/25/2009 Physician Brazil
Primary
Concomitant
Urethral Meatus Stenosis Other Serious 1/1/1962 Male 174 lb 10/28/2009 Consumer United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious Male 11/6/2009 Physician United States
Primary
Concomitant
Convulsion Other Serious 36 Female 11/6/2009 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Death 10/30/2009 29 Male 247 lb 11/4/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 154 lb 11/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization Female 12/4/2009 Japan
Primary
Concomitant
Vomiting Other Serious Female 12/16/2009 Japan
Primary
Secondary
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 70 Female 12/21/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious Female 12/29/2009 Japan
Primary
Secondary
Drug Toxicity Death 56 Male 1/8/2010 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 56 Male 2/24/2010 Physician United States
Primary
Secondary
Vomiting Other Serious Female 3/5/2010 Japan
Primary
Secondary
Urinary Tract Malformation Congenital Anomaly 1/1/2009 3/9/2010 Other Health Professional Israel
Primary
Secondary
Metabolic Acidosis Hospitalization 9 Female 4/26/2010
Primary
Secondary
Concomitant
Drug Toxicity Death 56 Female 162 lb 5/3/2010 Consumer United States
Primary
Secondary
Concomitant
Coma Hospitalization 1 Female 5/11/2010 Other Health Professional Japan
Primary
Concomitant
Metabolic Acidosis Hospitalization 9 Female 5/8/2010 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/27/2008 41 Female 5/24/2010 Lawyer United States
Primary
Concomitant
Hepatotoxicity Other Serious 3 Male 24 lb 5/31/2010 Physician Turkey
Primary
Concomitant
Status Epilepticus Life Threatening 4/7/2010 25 Female 110 lb 5/26/2010 Physician Japan
Primary
Concomitant
Pneumonia Death 4/20/2010 63 Male 6/1/2010 Physician Japan
Primary
Concomitant
Pneumonia Aspiration Other Serious 4/20/2010 63 Male 6/14/2010 Physician Japan
Primary
Concomitant
Rash Erythematous Hospitalization 1 Female 6/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 4/18/2010 73 Male 6/23/2010 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 66 Male 6/24/2010 Physician Japan
Primary
Concomitant
Rash Erythematous Hospitalization 1 Female 6/25/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 9/11/2008 39 Male 7/1/2010 Physician Japan
Primary
Concomitant
Weight Increased 7/9/2007 67 Female 85 lb 7/15/2010 Other Health Professional United States
Primary
Concomitant
Oxygen Consumption Increased 2/4/2008 50 Male 186 lb 7/19/2010 Consumer United States
Primary
Concomitant
Hyperhidrosis Hospitalization 4/1/2010 19 Female 143 lb 7/20/2010 Other Health Professional Portugal
Primary
Concomitant
Urethral Repair Other Serious 40 Male 7/21/2010 Other Health Professional Netherlands
Primary
Secondary
Mental Disability Other Serious Female 7/22/2010 Other Health Professional Netherlands
Primary
Secondary
Unresponsive To Stimuli Other Serious 1/27/2008 41 Female 7/22/2010 Lawyer United States
Primary
Concomitant
Nose Deformity Other Serious Male 7/23/2010 Other Health Professional Netherlands
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 1/18/2010 Male 7 lb 7/26/2010 Physician Japan
Primary
Concomitant
Overdose Other Serious 6 Male 8/3/2010 Other Health Professional China
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 1/18/2010 Male 7 lb 8/5/2010 Physician Japan
Primary
Concomitant
Myoclonus Other Serious 11 Male 8/6/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Convulsion Other Serious 1/1/2007 56 Female 321 lb 8/6/2010 Consumer United States
Primary
Secondary
Concomitant
Palpitations Female 180 lb 8/6/2010 Consumer United States
Primary
Secondary
Concomitant
Hot Flush Female 8/6/2010 Consumer United States
Primary
Secondary
Concomitant
Overdose Life Threatening 10 Male 8/10/2010 Other Health Professional China
Primary
Secondary
Epilepsy Life Threatening 10 Female 8/10/2010 Other Health Professional China
Primary
Secondary
Road Traffic Accident Other Serious 8/1/2010 56 Male 200 lb 8/17/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 6/1/2010 46 Female 160 lb 8/13/2010 United States
Primary
Concomitant
Myoclonus Other Serious 11 Male 8/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/16/2009 69 Female 110 lb 8/27/2010 Physician Japan
Primary
Concomitant
Cholecystitis Acute Other Serious 8/26/2010 47 Female 9/2/2010 Other Health Professional Argentina
Primary
Secondary
Concomitant
Intentional Drug Misuse Other Serious 55 Male 9/27/2010
Primary
Secondary
Concomitant
Myoclonus Other Serious 23 Male 9/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Virologic Failure Other Serious 12/1/2009 70 Male 10/8/2010 Consumer United States
Primary
Secondary
Concomitant
Interacting
Vomiting Hospitalization 10/3/2010 80 Female 10/21/2010 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 11/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 61 Female 11/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 61 Female 12/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Somnolence Hospitalization 2/24/2006 Female 11/16/2010 Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 61 Female 11/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Somnolence Other Serious 59 12/7/2010 Other Health Professional Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 61 Female 12/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Somnolence Other Serious 59 12/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 9/1/2008 58 Male 12/21/2010 Other Health Professional Japan
Primary
Concomitant
Irritable Bowel Syndrome Hospitalization 10/3/2010 80 Female 12/23/2010 Consumer United States
Primary
Concomitant
Syncope Hospitalization 9/1/2008 58 Male 12/29/2010 Japan
Primary
Concomitant
Respiratory Arrest Death 1/1/2009 41 Male 1/10/2011 Physician United States
Primary
Secondary
Congenital Nail Disorder Congenital Anomaly 1/18/2010 Male 7 lb 1/11/2011 Physician Japan
Primary
Concomitant
Headache Hospitalization 10/1/2008 58 Male 1/17/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 41 Male 1/19/2011 Physician United States
Primary
Secondary
Off Label Use Other Serious 1/1/2010 52 Male 210 lb 1/18/2011 Consumer United States
Primary
Concomitant
Interacting
Antisocial Behaviour Other Serious 11/29/2010 50 Female 160 lb 1/20/2011 Consumer United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction 1/4/2011 45 Male 1/7/2011 Other Health Professional Greece
Primary
Secondary
Concomitant
Cardiac Index Decreased Death 10/3/2010 50 Female 1/31/2011 Pharmacist Canada
Primary
Concomitant
Poisoning Death 1/1/2009 41 Male 1/27/2011 Physician United States
Primary
Secondary
Lethargy Other Serious 1/1/2011 52 Male 210 lb 2/10/2011 Consumer United States
Primary
Concomitant
Interacting
Back Pain Other Serious 12/1/2007 20 Female 2/15/2011 Lawyer United States
Primary
Concomitant
Somnolence Other Serious 1/26/2011 Other Health Professional China
Primary
Concomitant
Chest Discomfort Hospitalization 1/4/2011 45 Male 2/8/2011 Physician Greece
Primary
Secondary
Concomitant
Confusional State Other Serious 1/1/2011 52 Male 210 lb 2/17/2011 United States
Primary
Secondary
Concomitant
Inhibitory Drug Interaction Other Serious 1/1/2011 52 Male 210 lb 3/1/2011 Consumer United States
Primary
Concomitant
Interacting
Multiple Drug Overdose Accidental Death 41 Male 3/9/2011 Physician United States
Primary
Secondary
Metabolic Acidosis Hospitalization 50 Female 3/23/2011 Consumer United Kingdom
Primary
Concomitant
Cardiac Arrest Death 41 Male 3/24/2011 Physician United States
Primary
Secondary
Drug Ineffective Hospitalization 1/1/2010 61 Female 4/8/2011 Consumer Brazil
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 73 Male 4/8/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 50 Female 4/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Metabolic Acidosis Hospitalization 5/1/2010 50 Female 4/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Depressed Level Of Consciousness Other Serious 50 Female 4/29/2011 Other Health Professional United Kingdom
Primary
Interacting
Tachypnoea Hospitalization 50 Female 5/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypothermia Other Serious 75 Female 5/26/2011 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/1/2010 27 Male 176 lb 6/22/2011 Physician Brazil
Primary
Secondary
Concomitant
Face Injury Hospitalization 1/1/2009 23 Female 82 lb 6/24/2011 Consumer Brazil
Primary
Concomitant
Pyroglutamate Increased Hospitalization 50 Female 7/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Completed Suicide Other Serious 1/1/2008 56 Male 7/20/2011 Physician United States
Primary
Secondary
Rash Other Serious 10/18/2011 52 Female 139 lb 11/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2010 61 Female 12/15/2011 Consumer United States
Primary
Secondary
Concomitant
Hyperaemia Hospitalization 1/1/2010 61 Female 12/15/2011 Consumer Brazil
Primary
Secondary
Concomitant
Hyperaemia Hospitalization 1/1/2010 61 Female 12/28/2011 Consumer Brazil
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/1/2010 61 Female 12/29/2011 Consumer United States
Primary
Secondary
Concomitant
Lethargy 1/1/2010 52 Male 210 lb 1/6/2012 Consumer United States
Primary
Concomitant
Interacting
Drug Effect Decreased Other Serious 1/1/1980 22 Male 179 lb 1/18/2012 Consumer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 8/27/2004 1 Male 1/31/2012 Lawyer United States
Primary
Concomitant
Motor Dysfunction Hospitalization 3/21/2012 45 Male 4/2/2012 Consumer Brazil
Primary
Concomitant
Headache Other Serious 1/1/2012 39 Male 5/15/2012 Consumer Brazil
Primary
Concomitant
Convulsion Other Serious 1/1/2012 39 Male 5/18/2012 Consumer Brazil
Primary
Concomitant
Death Death 6/29/2008 41 Male 273 lb 6/5/2012 Other Health Professional Germany
Primary
Concomitant
Pain In Extremity Hospitalization 3/21/2012 45 Male 7/9/2012 Consumer Brazil
Primary
Secondary
Concomitant
Protrusion Tongue Other Serious 31 Female 7/9/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myositis Other Serious 38 Female 8/15/2012 Physician United States
Primary
Concomitant
Hypoaesthesia Oral 8/16/2012 62 Male 190 lb 8/22/2012 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 75 Female 12/26/2012 Other Health Professional Us
Primary
Concomitant
Interacting
Weight Decreased Other Serious 12/17/1988 33 Female 110 lb 10/19/2012 Consumer Ca
Primary
Secondary
Concomitant
Hyperammonaemic Encephalopathy Other Serious 42 Male 11/13/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Interacting
Vitreous Detachment Other Serious 5/2012 64 Male 9/12/2012 Consumer Gb
Primary
Secondary
Concomitant
Toxicity To Various Agents Hospitalization 6/6/2012 62 Male 128 lb 9/18/2012 Physician Jp
Primary
Concomitant
Drug Ineffective Other Serious 6 Male 10/16/2012 Physician Country Not Specified
Primary
Secondary
Concomitant

Drug Data