Peginterferon Alfa-2B combined with Ribavirin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatic Failure Death 47 Female 1/25/2006 Other Health Professional France
Primary
Secondary
Hypertensive Crisis Other Serious 12/26/2005 60 Female 145 lb 2/1/2006 Physician United States
Primary
Secondary
Malaise Required Intervention 1/1/2005 48 Female 155 lb 9/2/2005 Consumer United States
Primary
Secondary
Concomitant
Drug Specific Antibody Absent Other Serious Female 10/17/2006 Physician United States
Primary
Secondary
Productive Cough Other Serious 9/10/2001 Male 10/27/2006 Physician Japan
Primary
Secondary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Walking Disability Other Serious 10/14/1996 Male 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 3/24/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/23/2006 35 Male 130 lb 12/19/2006 Physician United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain 12/30/2005 43 Female 130 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Suicide Attempt Other Serious 6/17/2005 Male 4/5/2007 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 1/3/2007 Male 216 lb 3/30/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Life Threatening 2/25/2007 Male 4/26/2007 Physician Netherlands
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 4/27/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 5/17/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/25/2007 Male 5/18/2007 Physician Netherlands
Primary
Secondary
Concomitant
Walking Disability Other Serious 2/23/1998 Male 6/6/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/14/2007 Physician Japan
Primary
Secondary
Concomitant
Varices Oesophageal Life Threatening 12/29/2004 27 Male 6/15/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Acute Psychosis Hospitalization 7/15/2007 Male 187 lb 7/20/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 7/26/2007 Physician United States
Primary
Secondary
Concomitant
Walking Disability Other Serious 2/23/1998 Male 7/31/2007 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 8/8/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 234 lb 8/21/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/26/2007 Male 234 lb 8/27/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 9/4/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 9/10/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 9/18/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 9/18/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 9/24/2007 Physician United States
Primary
Secondary
Concomitant
Acute Psychosis Other Serious 7/15/2007 Male 187 lb 9/25/2007 Physician United States
Primary
Secondary
Concomitant
Self-medication Other Serious 6/26/2007 Male 238 lb 10/1/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/25/2007 Male 10/1/2007 Physician Netherlands
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 10/8/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/25/2007 Male 10/15/2007 Physician Netherlands
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 10/15/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 10/22/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 10/29/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/26/1999 Male 11/1/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 11/5/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 6/26/2007 Male 238 lb 11/19/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 11/27/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 12/7/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 1/21/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 8/1/2007 41 Male 180 lb 1/22/2008 Physician Brazil
Primary
Secondary
Weight Decreased Other Serious 49 Female 232 lb 2/1/2008 United States
Primary
Secondary
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 2/21/2008 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 3/13/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/30/2005 Male 3/13/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 3/13/2008 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 11/18/2006 Male 3/18/2008 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/30/2005 Male 4/23/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/30/2008 Male 174 lb 5/20/2008 Physician Canada
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/26/1999 Male 6/3/2008 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/26/2007 Male 238 lb 6/13/2008 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 54 Female 6/13/2008 United States
Primary
Secondary
Oligohydramnios Other Serious 7/23/2007 Female 7/9/2008 Consumer France
Primary
Concomitant
Myxoedema Coma Hospitalization 5/25/2008 68 Female 143 lb 7/8/2008 Physician Germany
Primary
Secondary
Concomitant
Tinnitus 8/1/2007 Female 7/25/2008 Pharmacist United States
Primary
Secondary
Anaemia Other Serious 4/6/2008 40 Male 10/9/2008 Consumer France
Primary
Secondary
Lichenoid Keratosis Other Serious 50 Male 10/31/2008 Other Health Professional Italy
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/3/2007 65 Female 10/30/2008 Consumer United States
Primary
Secondary
Lichenoid Keratosis Other Serious 1/1/2002 50 Male 11/5/2008 Other Health Professional Italy
Primary
Secondary
White Blood Cell Count Decreased 4/1/2008 Female 12/12/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 57 Male 2/11/2009 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 3/30/2005 Male 3/6/2009 Physician Japan
Primary
Secondary
Concomitant
Palpitations Hospitalization 12/15/2009 60 Male 165 lb 12/16/2009 Pharmacist United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 11/3/2008 38 Female 3/4/2010 Physician United States
Primary
Secondary
Phlebitis Hospitalization 8/31/2009 60 Male 4/2/2010 Physician Taiwan, Province Of China
Primary
Secondary
Pneumonia Hospitalization 8/11/2009 66 Female 4/2/2010 Physician Taiwan, Province Of China
Primary
Secondary
Visual Field Defect Other Serious 50 Male 4/5/2010 France
Primary
Secondary
Parkinsonism Other Serious 52 Male 4/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Amyloidosis Hospitalization 8/11/2009 66 Female 5/11/2010 Physician Taiwan, Province Of China
Primary
Secondary
Abdominal Sepsis Life Threatening 5/5/2010 49 Male 5/14/2010 Physician Brazil
Primary
Secondary
Jaundice Other Serious 10/1/2003 22 Male 6/1/2010 Other Health Professional Germany
Primary
Secondary
Virologic Failure Other Serious 9/1/2006 62 Female 6/1/2010 Other Health Professional Germany
Primary
Secondary
Sleep Apnoea Syndrome 4/25/2010 57 Female 5/28/2010 Mexico
Primary
Secondary
Sjogren's Syndrome 67 Female 89 lb 6/7/2010 Physician Japan
Primary
Concomitant
Stress Hospitalization 4/7/2010 40 Female 101 lb 6/2/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/25/2009 27 Female 6/3/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 5/13/2010 43 Male 6/3/2010 Physician Spain
Primary
Secondary
Lymphadenitis Hospitalization 4/16/2010 48 Male 6/9/2010 Physician France
Primary
Secondary
Vomiting Hospitalization 5/20/2010 53 Male 271 lb 6/11/2010 Physician Italy
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 5/13/2010 43 Male 6/11/2010 Physician Spain
Primary
Secondary
Autoimmune Hepatitis Other Serious 4/30/2010 27 Male 6/11/2010 Physician Ukraine
Primary
Secondary
Thrombocytopenia Hospitalization 3/30/2008 56 Male 159 lb 6/22/2010 Physician Canada
Primary
Secondary
Concomitant
Parkinsonism Other Serious 52 Male 6/17/2010 United Kingdom
Primary
Secondary
Stress Hospitalization 4/7/2010 40 Female 101 lb 6/22/2010 Physician Japan
Primary
Secondary
Concomitant
Hypothyroidism Other Serious 7/1/2005 34 Female 137 lb 6/24/2010 Physician Turkey
Primary
Secondary
Pyrexia Hospitalization 5/13/2010 43 Male 6/24/2010 Physician Spain
Primary
Secondary
Pyrexia Hospitalization 10/29/2008 55 Female 145 lb 6/25/2010 Physician Brazil
Primary
Secondary
Concomitant
Serum Ferritin Decreased Other Serious 1/1/2003 36 Female 6/29/2010 Physician Italy
Primary
Secondary
Thrombocytopenia Hospitalization 5/14/2010 48 Male 7/1/2010 Physician Pakistan
Primary
Secondary
Autoimmune Hepatitis Other Serious 4/30/2010 27 Male 7/6/2010 Physician Ukraine
Primary
Secondary
Varices Oesophageal Other Serious 11/1/1998 63 Female 7/8/2010 Physician France
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 1/1/2006 73 Male 7/8/2010 Physician Japan
Primary
Secondary
Portal Hypertensive Gastropathy Hospitalization 76 Female 7/8/2010 Other Health Professional Greece
Primary
Secondary
Concomitant
Muscle Necrosis Hospitalization 4/7/2010 49 Male 187 lb 7/21/2010 Physician Canada
Primary
Secondary
Stress Hospitalization 4/7/2010 40 Female 101 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 5/13/2010 43 Male 8/2/2010 Physician Spain
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 7/7/2010 50 Male 8/3/2010 Physician Egypt
Primary
Secondary
Vomiting Other Serious 7/7/2010 50 Male 8/2/2010 Physician Egypt
Primary
Secondary
Thyroid Disorder Other Serious 8/17/2010 Other Health Professional Tunisia
Primary
Secondary
Thrombocytopenia Hospitalization 4/16/2010 48 Male 8/11/2010 Physician France
Primary
Secondary
Concomitant
Vomiting Other Serious 8/2/2010 50 Male 8/20/2010 Physician Egypt
Primary
Secondary
Stress Hospitalization 4/7/2010 40 Female 101 lb 8/25/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/9/2010 Physician Brazil
Primary
Secondary
Pulmonary Fibrosis Other Serious 9/14/2010 Other Health Professional Hungary
Primary
Secondary
Thrombocytopenia Other Serious 9/20/2010 Other Health Professional Netherlands
Primary
Secondary
Sensation Of Foreign Body Other Serious 1/1/2008 52 Male 9/9/2010 Consumer Spain
Primary
Secondary
Tuberculosis Hospitalization 4/16/2010 48 Male 9/10/2010 Physician France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/11/2009 66 Female 9/13/2010 Physician Taiwan, Province Of China
Primary
Secondary
Pneumonia Hospitalization 7/11/2009 66 Female 9/20/2010 Physician Taiwan, Province Of China
Primary
Secondary
Thrombocytopenia Other Serious 54 Female 9/23/2010 Physician Japan
Primary
Secondary
Thrombocytopenia Hospitalization 7/26/2010 48 Male 9/22/2010 Physician France
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 5/20/2010 53 Male 271 lb 9/22/2010 Physician Italy
Primary
Secondary
Concomitant
Pancytopenia Other Serious 6/8/2010 54 Male 10/18/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization 33 Female 10/27/2010 Other Health Professional Korea, Republic Of
Primary
Secondary
Thrombocytopenia Other Serious 10/28/2010 Other Health Professional United States
Primary
Secondary
Stress Hospitalization 4/7/2010 40 Female 101 lb 10/21/2010 Physician Japan
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 10/8/2010 58 Male 10/25/2010 Canada
Primary
Secondary
Urinary Tract Infection Other Serious 11/8/2010 Other Health Professional Netherlands
Primary
Secondary
Skin Ulcer Other Serious 1/1/2003 42 Female 11/8/2010 Other Health Professional Brazil
Primary
Secondary
Suicide Attempt Hospitalization 4/7/2010 40 Female 101 lb 10/29/2010 Physician Japan
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/2003 42 Female 11/12/2010 Consumer United Kingdom
Primary
Secondary
Weight Decreased Other Serious 48 Male 143 lb 11/9/2010 Physician Australia
Primary
Secondary
Suicide Attempt Other Serious 11/23/2010 Physician France
Primary
Secondary
Autoimmune Thrombocytopenia Other Serious 7/1/2006 72 Female 119 lb 11/12/2010 Other Health Professional Japan
Primary
Secondary
Weight Decreased Other Serious 11/24/2010 Other Health Professional Slovenia
Primary
Secondary
Splenomegaly Hospitalization 10/8/2010 58 Male 11/11/2010 Physician Canada
Primary
Secondary
Weight Decreased Other Serious 11/29/2010 Other Health Professional Slovakia (Slovak Republic)
Primary
Secondary
Weight Decreased Other Serious 11/30/2010 Other Health Professional Italy
Primary
Secondary
Vomiting Other Serious 12/3/2010 Other Health Professional Italy
Primary
Secondary
Hepatic Neoplasm Other Serious 11/24/2010 Physician Canada
Primary
Secondary
Hepatic Neoplasm Hospitalization 9/15/2010 60 Male 220 lb 11/30/2010 Physician Canada
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/15/2010 Other Health Professional United States
Primary
Secondary
Urinary Tract Infection Hospitalization 54 Female 12/1/2010 Physician Netherlands
Primary
Secondary
Death Death 62 Male 12/8/2010 Physician Canada
Primary
Secondary
Concomitant
Small For Dates Baby Other Serious 7/6/2009 Female 3 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/14/2010 Physician United States
Primary
Secondary
Suicide Attempt Hospitalization 4/7/2010 40 Female 101 lb 12/16/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/20/2010 United States
Primary
Secondary
Swelling Face Other Serious 12/20/2010 India
Primary
Secondary
Scrotal Swelling Hospitalization 12/11/2010 63 Male 250 lb 12/20/2010 Physician Canada
Primary
Secondary
Concomitant

Drug Data