Paracetamol combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tremor Disability 9/10/2005 69 Male 1/10/2006 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2000 83 Female 99 lb 1/25/2006 United Kingdom
Primary
Concomitant
Sepsis Hospitalization 12/9/2004 Male 157 lb 2/9/2006 United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 2/24/2006 55 Female 260 lb 3/28/2006 Other Health Professional Australia
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 6/26/2005 71 Male 200 lb 4/20/2006 Physician Australia
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Other Serious 66 Male 201 lb 2/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 80 Male 5/3/2007
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 75 Female 5/3/2007
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 58 Female 5/18/2007 Sweden
Primary
Interacting
International Normalised Ratio Increased Life Threatening 4/19/2007 78 5/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 66 Male 201 lb 7/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 77 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Other Serious 68 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Other Serious 58 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Death 78 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Death 67 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Other Serious 81 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Other Serious 87 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Death 80 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 86 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Retroperitoneal Haematoma Hospitalization 66 Male 8/16/2007 Pharmacist United Kingdom
Primary
Concomitant
Restlessness Hospitalization 8/26/2007 79 Female 9/27/2007 Physician Italy
Primary
Concomitant
Balance Disorder Hospitalization 1/16/2009 2/2/2009 Physician Sweden
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 12/17/2008 2/3/2009 Other Health Professional France
Primary
Concomitant
Interacting
Urticaria Hospitalization 3/29/2008 2/10/2009 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/15/2008 Male 159 lb 2/26/2009 United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 1/27/2009 Female 185 lb 4/1/2009 Physician Ireland
Primary
Concomitant
Vomiting Hospitalization 1/9/2009 4/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/9/2009 4/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/27/2008 4/24/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/9/2009 35 6/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gout Other Serious 3/12/2009 72 Female 6/25/2009 Physician United Kingdom
Primary
Concomitant
Gout Other Serious 3/12/2009 72 Female 7/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Cancer Other Serious 3/1/2008 Male 203 lb 7/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Osteoradionecrosis Other Serious 10/31/2008 Female 123 lb 7/2/2009 Physician Switzerland
Primary
Secondary
Concomitant
Vocal Cord Paralysis Hospitalization 7/25/2008 Female 108 lb 7/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/7/2009 Consumer United States
Primary
Secondary
Concomitant
Syncope Other Serious 2/8/2009 75 Female 132 lb 8/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 62 Male 8/14/2009 Consumer United States
Primary
Concomitant
Haematoma Hospitalization 90 Female 8/28/2009 United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 8/27/2009 Male 139 lb 10/5/2009 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/2/2009 86 10/21/2009 Physician Sweden
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/2/2009 86 Male 161 lb 12/11/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 10/2/2009 Female 123 lb 12/16/2009 Pharmacist United States
Primary
Concomitant
Interacting
Transient Ischaemic Attack Other Serious 2/24/2009 Female 1/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 10/2/2009 86 Male 161 lb 2/16/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/12/2007 19 Male 3/24/2010 Physician New Zealand
Primary
Concomitant
Hypotension Other Serious 85 Female 4/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Subdural Haemorrhage Other Serious 2/12/2010 70 Male 6/14/2010 Other Health Professional Ireland
Primary
Secondary
Concomitant
Haematuria Hospitalization 9/1/2008 78 Male 6/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Melaena Other Serious 8/1/2002 76 Female 6/16/2010 Other Health Professional South Africa
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 10/7/2009 66 Male 241 lb 6/23/2010 Physician United Kingdom
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 7/5/2010 52 Female 203 lb 7/22/2010 Other Health Professional Australia
Primary
Concomitant
Subdural Haemorrhage Other Serious 2/12/2010 70 Male 7/28/2010 Other Health Professional Ireland
Primary
Secondary
Concomitant
Thyroiditis Other Serious 80 Male 8/9/2010 Other Health Professional Ireland
Primary
Concomitant
Facial Paresis Other Serious 8/9/2010 70 Male 231 lb 9/3/2010 Consumer Finland
Primary
Concomitant
Renal Failure Hospitalization 10/2/2009 86 Male 161 lb 9/6/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Skin Lesion Other Serious 9/27/2010 72 Male 232 lb 11/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/5/2010 69 Female 12/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/5/2010 69 Female 12/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 10/1/2010 69 Female 12/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/5/2010 69 Female 12/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 64 Female 12/10/2010 Pharmacist Denmark
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 9/5/2010 69 Female 12/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/5/2010 69 Female 1/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 64 Female 1/14/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 90 Female 1/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Mobility Decreased Disability 10/1/2010 69 Female 1/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 64 Female 1/10/2011 Pharmacist Denmark
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/5/2011 Female 2/1/2011 Pharmacist United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 1/5/2011 Female 2/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 1/5/2011 Female 2/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Mucopolysaccharidosis Hospitalization 6/17/2008 5 Male 30 lb 1/31/2011 Other Health Professional France
Primary
Concomitant
Contusion Hospitalization 9/18/2010 87 Female 112 lb 2/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malnutrition Hospitalization 12/14/2009 78 Male 100 lb 2/28/2011 Physician France
Primary
Concomitant
Atrial Fibrillation Other Serious 2/16/2010 70 Male 2/11/2011 United Kingdom
Primary
Concomitant
Injection Site Haemorrhage Hospitalization 9/18/2010 3/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 9/18/2010 87 Female 112 lb 3/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Contusion Hospitalization 9/18/2010 3/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 9/18/2010 87 Female 112 lb 3/4/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Death 8/1/2010 87 Female 2/25/2011 United Kingdom
Primary
Secondary
Concomitant
Gout Other Serious 3/12/2009 72 Female 3/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Off Label Use Death 12/8/2010 3/24/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Off Label Use Hospitalization 12/8/2010 3/31/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/19/2011 80 Male 3/22/2011 Other Health Professional
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/15/2008 64 Female 141 lb 4/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Heparin-induced Thrombocytopenia Death 2/12/2010 70 Male 5/5/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Skin Haemorrhage Other Serious 6/27/2011 79 Male 7/15/2011 Physician Slovenia
Primary
Concomitant
Blood Creatinine Increased Disability 9/5/2010 69 Female 8/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Asthenia Disability 9/5/2010 69 Female 8/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Life Threatening 9/5/2010 69 Female 8/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diarrhoea 8/10/2011 48 Male 8/15/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/4/2012 73 Female 216 lb 2/28/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Constipation Other Serious 1/24/2012 66 Male 3/8/2012 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Death 10/1/2011 80 Male 159 lb 4/2/2012 Physician Australia
Primary
Concomitant
International Normalised Ratio Increased Other Serious 89 Male 119 lb 8/30/2012 Other Health Professional Gb
Primary
Concomitant
Interacting
Pneumonia Death 1/12/2012 60 Female 11/7/2012 Physician Gb
Primary
Concomitant
Tricuspid Valve Incompetence Death 5/9/2012 84 Female 80 lb 9/13/2012 Consumer Ie
Primary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 11/14/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 8/30/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 10/24/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 4/2012 59 Female 10/23/2012 Physician Gb
Primary
Concomitant
Prostate Cancer Hospitalization 74 Male 9/17/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 10/17/2011 80 Female 287 lb 9/11/2012 Other Health Professional Gb
Primary
Concomitant
Interacting
Retroperitoneal Haemorrhage Death 10/17/2011 80 Female 287 lb 10/2/2012 Physician Gb
Primary
Concomitant
Interacting
Enuresis 8/1/2012 86 Male 141 lb 10/1/2012 Other Health Professional Gb
Primary
Concomitant
Subdural Haematoma Other Serious 2011 Male 9/29/2012 Physician Au
Primary
Secondary
Concomitant
Ovarian Cancer Hospitalization 7/26/2012 60 Male 176 lb 9/11/2012 Us
Primary
Secondary
Concomitant
Hepatic Enzyme Abnormal Other Serious Male 9/18/2012 Physician Ie
Primary
Concomitant
Thrombosis Hospitalization 7/11/2012 61 Male 198 lb 10/1/2012 Consumer Mx
Primary
Secondary
Concomitant
Pain Other Serious 73 Male 10/16/2012 Other Health Professional Au
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 9/1/2012 21 Female 11/5/2012 Physician Gb
Primary
Concomitant
Memory Impairment Disability 80 Female 10/26/2012 Other Health Professional Gb
Primary
Concomitant
Memory Impairment Disability 80 Female 10/31/2012 Pharmacist Gb
Primary
Concomitant
Hypomagnesaemia Life Threatening 10/21/2012 76 Male 11/5/2012 Other Health Professional Gb
Primary
Concomitant
Hypomagnesaemia Life Threatening 10/21/2012 76 Male 11/9/2012 Physician Gb
Primary
Concomitant
Hypomagnesaemia Life Threatening 10/21/2012 76 Male 11/6/2012 Other Health Professional Gb
Primary
Concomitant
Hypomagnesaemia Life Threatening 10/21/2012 76 Male 11/16/2012 Other Health Professional Gb
Primary
Concomitant
Hypomagnesaemia Life Threatening 10/21/2012 76 Male 11/18/2012 Physician Gb
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/9/2012 57 Female 196 lb 1/9/2013 Physician Us
Primary
Concomitant
Osteomyelitis Hospitalization 11/27/2012 46 Male 163 lb 12/18/2012 Other Health Professional Au
Primary
Concomitant
Toxic Encephalopathy Other Serious 11/28/2012 81 Male 12/18/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Encephalopathy Hospitalization 11/28/2012 81 Male 12/27/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Paraesthesia Disability 11/11/2012 81 Male 161 lb 12/24/2012 Other Health Professional Gb
Primary
Concomitant
Paraesthesia Disability 11/11/2012 81 Male 161 lb 1/3/2013 Pharmacist Gb
Primary
Concomitant
Toxic Encephalopathy Hospitalization 11/28/2012 81 Male 12/27/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 11/14/2012 44 Male 205 lb 12/27/2012 Other Health Professional Gb
Primary
Concomitant
Mobility Decreased Other Serious 11/14/2012 44 Male 205 lb 12/28/2012 Other Health Professional Gb
Primary
Concomitant
Drug Interaction Hospitalization 58 Female 12/31/2012 Other Health Professional Se
Primary
Interacting
Drug Interaction Hospitalization 86 Female 12/31/2012 Other Health Professional Se
Primary
Interacting
Drug Interaction Hospitalization 68 Male 12/31/2012 Other Health Professional Se
Primary
Interacting
Drug Interaction Hospitalization 77 Female 12/31/2012 Other Health Professional Se
Primary
Secondary
Drug Interaction Death 80 Female 12/31/2012 Other Health Professional Se
Primary
Secondary
Interacting
Paraesthesia Disability 11/11/2012 81 Male 161 lb 1/3/2013 Other Health Professional Gb
Primary
Concomitant
Paraesthesia Disability 11/11/2012 81 Male 12/27/2012 Other Health Professional Us
Primary
Concomitant
Mobility Decreased Other Serious 11/14/2012 44 Male 12/27/2012 Other Health Professional Dk
Primary
Concomitant
Rectal Haemorrhage Other Serious 8/2012 89 Female 1/17/2013 Other Health Professional Nz
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 3/15/2012 86 Male 2/7/2013 Physician Gb
Primary
Concomitant
Medication Error Hospitalization 1/13/2013 76 Female 271 lb 2/1/2013 Other Health Professional Gb
Primary
Concomitant
Interacting
Tubulointerstitial Nephritis Life Threatening 78 Female 168 lb 3/5/2013 Physician Gb
Primary
Concomitant
Respiratory Failure Death 11/3/2012 76 Female 106 lb 3/6/2013 Physician Gb
Primary
Concomitant
Supraventricular Extrasystoles Hospitalization 77 Male 3/11/2013 Other Health Professional Gb
Primary
Concomitant
Interacting
Tubulointerstitial Nephritis Life Threatening 78 Female 168 lb 3/14/2013 Other Health Professional Gb
Primary
Concomitant
International Normalised Ratio Decreased Hospitalization 77 Male 3/15/2013 Pharmacist Gb
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 9/2012 62 Female 3/15/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Palpitations Other Serious Male 3/19/2013 Consumer Ie
Primary
Concomitant
Gastroenteritis Death 12/26/2002 80 Female 146 lb 3/21/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 77 Male 3/28/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Interacting
Memory Impairment Disability 80 Female 11/1/2012 Pharmacist Gb
Primary
Concomitant

Drug Data