Paracetamol combined with Tramadol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rales Life Threatening 11/11/2005 85 Female 1/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 6/21/2003 Female 2/9/2006 United Kingdom
Primary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 2/9/2006 United Kingdom
Primary
Concomitant
Sudden Death Disability 11/3/2005 Male 4/14/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/4/2004 60 Female 4/14/2006 Physician Netherlands
Primary
Concomitant
Tongue Ulceration Other Serious 10/1/2006 68 Female 185 lb 11/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 5/2/2007 57 Male 183 lb 11/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2007 Female 11/14/2007 Pharmacist United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 9/30/2008 61 Male 12/29/2008 Physician France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/1/2008 Male 12/30/2008 Other Health Professional France
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 7/10/2008 Female 12/31/2008 Physician United Kingdom
Primary
Concomitant
Colitis Hospitalization 9/12/2008 Female 12/31/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 12/1/2008 2/12/2009 Other Health Professional France
Primary
Secondary
Concomitant
Tremor Hospitalization 2/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Oedema Other Serious Female 2/13/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious Male 152 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/16/2009 87 Female 2/13/2009 Consumer Spain
Primary
Concomitant
Rash Maculo-papular Other Serious 1/16/2009 3/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 61 Female 161 lb 3/12/2009 Other Health Professional France
Primary
Concomitant
Tremor Hospitalization 3/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 3/30/2009 United Kingdom
Primary
Secondary
Concomitant
Diverticulitis Other Serious 1/7/2009 Female 231 lb 4/6/2009 Consumer United Kingdom
Primary
Concomitant
Transaminases Increased Other Serious 6/9/2008 Female 116 lb 4/8/2009 Physician Philippines
Primary
Concomitant
Unresponsive To Stimuli Other Serious Male 179 lb 4/8/2009 Germany
Primary
Concomitant
Unresponsive To Stimuli Other Serious Male 179 lb 4/8/2009 Germany
Primary
Concomitant
Chest Pain Hospitalization 3/1/2009 Male 220 lb 4/9/2009 Consumer United Kingdom
Primary
Concomitant
Transaminases Increased Other Serious 6/9/2008 Female 116 lb 4/9/2009 Physician Philippines
Primary
Concomitant
Visual Impairment Other Serious 3/1/2009 Female 163 lb 4/9/2009 Brazil
Primary
Concomitant
Serotonin Syndrome Other Serious 73 Female 4/14/2009 Other Health Professional Spain
Primary
Secondary
Vomiting Other Serious 1/1/2009 4/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 3/25/2009 16 Female 5/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 36 6/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 7/4/2008 Female 168 lb 7/9/2009 Physician Australia
Primary
Concomitant
Cushingoid Other Serious 11/1/2008 60 Male 7/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Other Serious 1/1/2009 60 7/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms Life Threatening Male 209 lb 7/21/2009 Consumer United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Life Threatening 4/17/2009 75 7/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 36 7/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Proteinuria Other Serious 5/1/2009 51 Female 7/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Peripheral Ischaemia 12/1/2008 66 Male 7/23/2009 United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 6/23/2009 82 7/30/2009 Other Health Professional France
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/12/2008 Male 7/31/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Proteinuria Other Serious 5/1/2009 51 Female 8/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 7/4/2009 65 8/4/2009 Brazil
Primary
Concomitant
Renal Failure Acute Life Threatening 6/30/2009 61 8/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Stress Fracture Disability 3/1/2008 Female 7/31/2009 United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 6/6/2007 Male 8/10/2009 Physician Chile
Primary
Concomitant
Wound Other Serious 1/1/2009 Female 163 lb 8/10/2009 Brazil
Primary
Concomitant
Vomiting Other Serious 8/14/2009 Other Health Professional Italy
Primary
Secondary
Upper Gastrointestinal Haemorrhage Other Serious 4/1/2008 64 8/14/2009 Physician Philippines
Primary
Secondary
Concomitant
Gastric Ulcer Other Serious 77 Female 8/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/12/2008 Male 8/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 62 Male 8/14/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/23/2009 82 8/24/2009 Other Health Professional France
Primary
Secondary
Concomitant
Surgery Other Serious 1/1/2009 60 8/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/4/2009 65 8/27/2009 Other Health Professional Brazil
Primary
Concomitant
Myocardial Infarction Death 8/25/2009 93 9/17/2009 Consumer Peru
Primary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 36 9/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Wrist Fracture Hospitalization 11/27/2008 73 9/30/2009 Physician France
Primary
Secondary
Concomitant
Ulcer Hospitalization 63 Female 10/15/2009 Netherlands
Primary
Secondary
Renal Failure Hospitalization 7/4/2009 65 10/30/2009 Other Health Professional Brazil
Primary
Concomitant
Drug Toxicity Death 45 Female 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Pituitary Tumour Benign Other Serious 5/1/2008 51 Female 146 lb 11/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/17/2008 Male 11/19/2009 Physician Belgium
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 9/18/2009 48 Female 99 lb 12/17/2009 Pharmacist United Kingdom
Primary
Concomitant
Abdominal Pain Death 12/5/2009 Male 179 lb 12/24/2009 Other Health Professional Spain
Primary
Concomitant
Febrile Neutropenia Life Threatening 12/15/2008 Male 12/31/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Male 176 lb 1/6/2010 Physician Netherlands
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2009 Female 150 lb 1/6/2010 Pharmacist Australia
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 10/27/2008 76 Male 154 lb 1/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Drug Withdrawal Syndrome Hospitalization Female 1/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 12/23/2008 78 Female 1/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 12/15/2008 Male 123 lb 1/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Multiple Drug Overdose Death 45 Female 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Drug Withdrawal Syndrome Hospitalization Female 1/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intermittent Claudication Other Serious 7/10/2009 64 Male 164 lb 1/29/2010 Physician Netherlands
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Female 2/1/2010 Pharmacist United Kingdom
Primary
Concomitant
Nephrotic Syndrome Hospitalization 1/1/2009 75 Male 2/1/2010 Other Health Professional France
Primary
Secondary
Concomitant
Malnutrition Hospitalization 11/17/2009 58 Male 112 lb 2/4/2010 Physician France
Primary
Secondary
Concomitant
Rheumatoid Vasculitis Hospitalization 9/25/2009 Female 103 lb 2/4/2010 Physician United Kingdom
Primary
Concomitant
Myopericarditis Hospitalization 9/4/2009 Female 130 lb 2/4/2010 Consumer United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 12/23/2009 63 Male 2/5/2010 Pharmacist United Kingdom
Primary
Concomitant
Malnutrition Hospitalization 11/17/2009 58 Male 112 lb 2/8/2010 Physician France
Primary
Secondary
Concomitant
Upper Limb Fracture Hospitalization 6/13/2009 Male 193 lb 2/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Malnutrition Hospitalization 11/17/2009 59 Male 117 lb 2/11/2010 Physician United States
Primary
Concomitant
Interacting
Swelling Face Other Serious 11/1/2009 51 Female 2/12/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 6/26/2008 Male 197 lb 2/12/2010 Physician France
Primary
Concomitant
White Blood Cell Count Increased Death 11/6/2009 Female 163 lb 2/12/2010 United Kingdom
Primary
Concomitant
Vomiting Other Serious 83 Female 2/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abscess Intestinal Hospitalization 1/23/2010 Female 249 lb 2/19/2010 Physician Australia
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 11/13/2009 Male 153 lb 3/23/2010 Physician Belgium
Primary
Secondary
Concomitant
Skin Cancer Other Serious 10/1/2007 Female 159 lb 3/24/2010 Consumer United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 51 Female 121 lb 4/9/2010 United Kingdom
Primary
Concomitant
Demyelination Life Threatening 1/5/2010 28 Female 141 lb 4/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 51 Female 121 lb 5/3/2010 United Kingdom
Primary
Concomitant
Spinal Cord Compression Other Serious 9/23/2009 60 Male 172 lb 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wrist Fracture Hospitalization 11/27/2008 73 Female 119 lb 5/5/2010 Physician France
Primary
Secondary
Concomitant
Myalgia Hospitalization 3/20/2010 84 Female 209 lb 5/20/2010 Other Health Professional
Primary
Concomitant
Impaired Healing Hospitalization 4/12/2010 60 203 lb 6/2/2010 Physician Netherlands
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 10/5/2009 36 Female 6/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Polyarthritis Hospitalization 11/30/2009 68 Female 196 lb 6/2/2010 Argentina
Primary
Concomitant
Intentional Self-injury Other Serious 5/10/2010 67 Male 6/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 4/15/2010 48 Male 6/11/2010 Physician United Kingdom
Primary
Concomitant
Pelvic Abscess Hospitalization 5/11/2010 52 Male 213 lb 6/11/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Subdural Haemorrhage Other Serious 2/12/2010 70 Male 6/14/2010 Other Health Professional Ireland
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/19/2010 Physician Belgium
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/20/2010 Physician Belgium
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 24 Female 7/21/2010 Physician United Kingdom
Primary
Secondary
Impaired Gastric Emptying Hospitalization 3/17/2010 41 Male 273 lb 7/21/2010 Physician Denmark
Primary
Concomitant
Vasculitis Hospitalization Female 7/21/2010 Philippines
Primary
Concomitant
Pleural Disorder Hospitalization 3/6/2010 31 Female 7/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/1/2009 8/18/2010 Physician France
Primary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 8/24/2010 Consumer United States
Primary
Secondary
Concomitant
Surgical Failure Other Serious 1/1/2006 60 Female 9/2/2010 Consumer Netherlands
Primary
Concomitant
Surgery Other Serious 1/1/2009 60 Male 9/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 8/25/2009 93 Male 9/16/2010 Consumer Peru
Primary
Concomitant
Tremor Other Serious 1/1/2009 29 Female 150 lb 9/16/2010 Pharmacist Australia
Primary
Secondary
Concomitant
Swelling Face Other Serious 11/1/2009 51 Female 9/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 51 Female 121 lb 9/16/2010 United Kingdom
Primary
Concomitant
Vasculitis Hospitalization Female 9/16/2010 Philippines
Primary
Concomitant
Splenic Haemorrhage Other Serious 2/3/2009 60 Female 157 lb 9/20/2010 Physician Czech Republic
Primary
Concomitant
Large Intestine Perforation Hospitalization 2/17/2010 64 Male 165 lb 9/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 8/1/2010 63 Female 9/27/2010 Other Health Professional France
Primary
Secondary
Concomitant
Wheezing Life Threatening 6/1/2010 75 Male 9/28/2010 Consumer United Kingdom
Primary
Concomitant
Haemoglobin Increased Other Serious 8/26/2010 52 Female 170 lb 9/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Intracranial Pressure Increased Hospitalization 9/15/2010 57 Male 154 lb 10/4/2010 Physician France
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 4/1/2008 64 Female 121 lb 10/7/2010 Physician Philippines
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 10/5/2009 36 Female 10/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukocytosis Other Serious 12/22/2009 93 Female 108 lb 10/11/2010 Physician France
Primary
Concomitant
Synovitis Other Serious 6/1/2010 51 Female 223 lb 10/11/2010 Physician United Kingdom
Primary
Concomitant
Intracranial Pressure Increased Hospitalization 9/15/2010 57 Male 154 lb 10/15/2010 Physician France
Primary
Concomitant
Large Intestine Perforation Hospitalization 4/8/2010 67 Female 143 lb 10/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Peritonitis Hospitalization 4/8/2010 67 Female 143 lb 10/29/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 10/11/2010 34 Female 11/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Pain Hospitalization 6/20/2009 71 Male 11/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Spinal Cord Compression Other Serious 9/23/2009 60 Male 172 lb 11/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/6/2009 70 Male 11/1/2010 Physician Germany
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2009 34 Female 11/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious Female 10/25/2010 Other Health Professional Sweden
Primary
Concomitant
Surgery Other Serious 1/1/2006 60 Female 11/8/2010 Consumer Netherlands
Primary
Concomitant
Surgery Other Serious 1/1/2006 60 Female 11/12/2010 Physician Netherlands
Primary
Concomitant
Hyponatraemia Hospitalization 10/26/2010 2 Female 11/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Haematoma Hospitalization 4/8/2010 67 Female 126 lb 12/8/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Wound Secretion Other Serious 12/16/2009 64 Female 12/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vasculitis Hospitalization Female 7/21/2010 Philippines
Primary
Concomitant
Surgery Other Serious 1/1/2009 60 8/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 8/25/2009 93 9/17/2009 Consumer Peru
Primary
Concomitant
Swelling Face Other Serious 11/1/2009 51 Female 2/12/2010 Consumer United Kingdom
Primary
Secondary
Concomitant

Drug Data