Pamidronate Disodium combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Other Serious 8/1/2004 1/18/2006 Physician Belgium
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 12/7/2004 66 Male 1/21/2006 United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Life Threatening 7/1/2005 53 Female 2/13/2006 Physician Spain
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2006 55 Female 3/15/2006 Pharmacist Ireland
Primary
Secondary
Tooth Extraction Other Serious 9/27/2005 81 Male 3/29/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Other Serious 5/4/2005 62 Female 102 lb 3/28/2006 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Other Serious Female 4/6/2006 Physician Australia
Primary
Secondary
Osteonecrosis Other Serious 5/1/2005 80 Female 132 lb 4/13/2006 Physician Portugal
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 6/16/2003 68 Male 4/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 2/8/2006 56 Female 106 lb 4/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 6/16/2003 68 Male 4/23/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death 3/16/2003 68 Male 4/20/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 61 Female 4/28/2006 Canada
Primary
Concomitant
Renal Failure Acute Death 3/16/2003 68 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
No Therapeutic Response Hospitalization 2/8/2006 56 Female 106 lb 5/6/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 9/1/2004 75 Male 5/15/2006 Physician Spain
Primary
Secondary
Tooth Extraction Other Serious 63 Male 5/23/2006 Greece
Primary
Secondary
Wound Debridement Other Serious 71 Female 5/23/2006 Greece
Primary
Secondary
Tooth Extraction Other Serious 11/1/2005 Female 5/23/2006 Other Health Professional New Zealand
Primary
Secondary
Wound Debridement Other Serious 76 Female 5/25/2006 Greece
Primary
Secondary
Osteonecrosis Other Serious Female 6/2/2006 Physician United Kingdom
Primary
Secondary
Osteonecrosis Other Serious 61 Female 6/15/2006 Canada
Primary
Concomitant
Procedural Hypotension Other Serious 61 Female 6/22/2006 Canada
Primary
Concomitant
Renal Failure Acute Other Serious 5/31/2006 53 Female 6/26/2006 Pharmacist United Kingdom
Primary
Secondary
Secretion Discharge Other Serious 3/1/2004 57 Male 7/6/2006 Physician Australia
Primary
Secondary
Tooth Extraction Other Serious 6/1/2006 70 Female 7/18/2006 Other Health Professional Canada
Primary
Concomitant
Wound Drainage Other Serious 9/21/2004 63 Male 8/8/2006 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 8/8/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/31/2006 53 Female 8/18/2006 Consumer United Kingdom
Primary
Secondary
Ureteral Stent Insertion Other Serious 5/30/2006 53 Female 8/23/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Tooth Loss Other Serious 8/25/2006 Physician Australia
Primary
Concomitant
Osteonecrosis Other Serious Female 8/26/2006 United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 8/26/2006 Physician United Kingdom
Primary
Secondary
Wound Debridement Other Serious 8/1/2005 58 Male 9/26/2006 Italy
Primary
Secondary
Radiculopathy Other Serious 2/1/2006 60 Male 9/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 76 Female 9/27/2006 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2003 63 Male 9/28/2006 Physician United Kingdom
Primary
Secondary
Osteonecrosis Disability 63 Male 10/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Other Serious 1/1/2006 Female 11/2/2006 Consumer Canada
Primary
Secondary
Wound Debridement Other Serious 53 Female 11/10/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 53 Female 11/22/2006 United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious Female 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/1/2005 Female 121 lb 1/3/2007 Physician Germany
Primary
Secondary
Wound Debridement Other Serious Female 1/13/2007 Physician United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 8/12/2005 58 Female 1/17/2007 Pharmacist Australia
Primary
Concomitant
Osteonecrosis Other Serious 64 Female 3/6/2007 United States
Primary
Secondary
Osteonecrosis Hospitalization 1/8/2007 63 Male 3/16/2007 Sweden
Primary
Secondary
Weight Increased Other Serious 1/23/2002 52 Male 3/27/2007 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/23/2002 52 Male 4/5/2007 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 64 Female 4/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious Female 5/10/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/1/2006 68 Female 5/18/2007 Sweden
Primary
Secondary
Concomitant
Pain In Jaw Disability Female 5/23/2007 United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2005 70 Male 3/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/13/2006 55 Female 3/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/1/2006 73 Female 187 lb 8/15/2007 Physician Germany
Primary
Secondary
Pain In Jaw Other Serious 1/1/2001 Female 8/22/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/1997 64 Female 9/4/2007 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/1997 64 Female 9/4/2007 United States
Primary
Secondary
Concomitant
Hepatic Failure Life Threatening 6/19/2007 Female 126 lb 9/12/2007 Physician Germany
Primary
Concomitant
Osteonecrosis Other Serious 1/31/2006 55 Female 8/23/2007 Other Health Professional United States
Primary
Concomitant
Pain In Jaw Other Serious 8/12/2005 58 Female 9/20/2007 Pharmacist Australia
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2001 Female 9/22/2007 Consumer United Kingdom
Primary
Secondary
Hypercalcaemia Hospitalization Female 10/3/2007 Pharmacist United Kingdom
Primary
Secondary
Rash Other Serious 6/19/2007 Female 126 lb 10/5/2007 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 83 Male 10/11/2007 Pharmacist United States
Primary
Secondary
Rash Other Serious 6/19/2007 Female 126 lb 10/23/2007 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 65 Male 11/12/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/1/2004 44 Male 132 lb 11/20/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Muscle Contractions Involuntary Hospitalization Male 11/25/2007 Physician Spain
Primary
Secondary
Muscle Contractions Involuntary Hospitalization Male 11/27/2007 Physician Spain
Primary
Secondary
Rash Other Serious 6/19/2007 Female 126 lb 11/27/2007 Physician Germany
Primary
Secondary
Concomitant
Wound Debridement Other Serious 6/1/2006 79 Male 153 lb 12/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2006 79 Male 153 lb 1/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 81 Female 1/15/2008 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 81 Female 192 lb 1/19/2008 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 79 Male 154 lb 1/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 7/1/2007 Female 126 lb 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious Female 2/19/2008 Physician United States
Primary
Secondary
Concomitant
Neoplasm Progression Other Serious 7/1/2007 Female 126 lb 3/4/2008 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 2/13/2008 Lawyer United States
Primary
Secondary
Scar Other Serious Female 4/3/2008 Lawyer United States
Primary
Secondary
Osteonecrosis Other Serious 4/21/2008 Physician Australia
Primary
Secondary
Neoplasm Progression Other Serious 7/1/2007 Female 126 lb 6/9/2008 Physician Germany
Primary
Secondary
Concomitant
Scar Other Serious Female 10/6/2008 Lawyer United States
Primary
Secondary
Osteonecrosis Other Serious 3/1/2005 Female 12/4/2008 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/1/2005 Female 132 lb 12/5/2008 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 12/19/2008 Other Health Professional United States
Primary
Secondary
Osteonecrosis Other Serious 8/1/2008 64 Female 1/30/2009 Other Health Professional Germany
Primary
Secondary
Osteonecrosis Other Serious Female 2/25/2009 Other Health Professional United States
Primary
Secondary
Physical Disability Other Serious Female 3/19/2009 Lawyer United States
Primary
Secondary
Swelling Hospitalization 5/1/2008 Female 4/2/2009 Physician Germany
Primary
Concomitant
Interacting
Tooth Extraction Other Serious 10/1/2003 76 Male 5/20/2009 Other Health Professional Spain
Primary
Interacting
Tumour Marker Increased Other Serious 9/1/2001 Female 6/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Parathyroid Tumour Malignant Other Serious 6/19/2009 Male 6/29/2009 Physician United States
Primary
Concomitant
Tumour Marker Increased Other Serious 9/1/2001 Female 7/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Toothache Other Serious 11/22/2006 Female 7/16/2009 Physician Japan
Primary
Secondary
Toothache Other Serious 11/22/2006 Female 7/16/2009 Physician Japan
Primary
Secondary
Sepsis Other Serious 5/19/2009 70 Male 120 lb 7/21/2009 Physician United States
Primary
Concomitant
Swelling Other Serious Female 298 lb 7/23/2009 Physician Canada
Primary
Secondary
Sepsis Other Serious 6/1/2009 70 Male 120 lb 7/24/2009 Physician United States
Primary
Concomitant
Pain Other Serious Female 8/19/2009 Lawyer United States
Primary
Secondary
Osteonecrosis Disability Female 8/5/2009 Consumer United States
Primary
Secondary
Osteonecrosis Disability Female 8/5/2009 Lawyer United States
Primary
Secondary
Weight Decreased Other Serious 12/1/1996 48 Female 132 lb 9/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Infiltration Other Serious 9/15/2006 28 9/17/2009 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 12/1/1996 48 Female 132 lb 10/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Surgery Other Serious 75 Female 11/12/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/19/2001 Female 11/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Other Serious Female 11/20/2009 United States
Primary
Secondary
Weight Increased Other Serious 4/19/2001 Female 11/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 9/1/2001 Female 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 5/9/1997 Female 120 lb 1/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/19/2001 Female 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/30/2003 Female 87 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2001 Female 2/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/19/2001 Female 2/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 5/9/1997 Female 120 lb 3/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/19/2001 Female 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 5/9/1997 Female 120 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 6/6/2009 37 Female 4/6/2010 Consumer Canada
Primary
Secondary
Tooth Extraction Other Serious Female 200 lb 4/8/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 74 Female 192 lb 4/8/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 74 Female 192 lb 4/12/2010 United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 1/19/2010 61 Female 5/6/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Wound Secretion Other Serious 5/9/1997 48 Female 120 lb 5/11/2010 United States
Primary
Secondary
Concomitant
Pain Other Serious Male 4/29/2010 Lawyer United States
Primary
Secondary
Pain Other Serious Male 5/4/2010 Lawyer United States
Primary
Secondary
Overdose Other Serious Female 5/5/2010 Lawyer United States
Primary
Secondary
Pain Other Serious Female 5/5/2010 Lawyer United States
Primary
Secondary
Overdose Other Serious Female 5/4/2010 Lawyer United States
Primary
Secondary
Pain Other Serious Female 5/4/2010 Lawyer United States
Primary
Secondary
Pain Other Serious Female 5/4/2010 Lawyer United States
Primary
Secondary
Death Death Female 5/28/2010 Canada
Primary
Secondary
Wound Secretion Other Serious 5/9/1997 48 Female 120 lb 6/15/2010 United States
Primary
Secondary
Concomitant
Vaginal Ulceration Other Serious 2/1/2010 69 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 78 Female 6/25/2010 United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 5/9/1997 48 Female 120 lb 6/29/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 78 Female 7/9/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 74 Female 192 lb 7/19/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 74 Female 192 lb 7/21/2010 United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Disability 1/19/2010 61 Female 7/27/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/19/2001 62 Female 7/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 74 Female 192 lb 8/11/2010 United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 6/2/2010 52 Female 159 lb 8/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 78 Female 9/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 5/9/1997 48 Female 120 lb 9/28/2010 United States
Primary
Secondary
Concomitant
Impaired Healing Other Serious Female 10/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 78 Female 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 78 Female 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data