Oxycontin combined with Xeloda

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteonecrosis Other Serious 8/1/2005 Female 1/12/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Female 3/11/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Female 5/5/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 3/7/2006 46 Male 5/2/2006 Pharmacist United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 50 Female 5/18/2006 United States
Primary
Secondary
Concomitant
Sinus Congestion Hospitalization 5/1/2006 27 Male 7/12/2006 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 43 Female 147 lb 8/11/2006 Consumer United States
Primary
Concomitant
Tooth Loss Other Serious 1/1/2004 43 Female 147 lb 8/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 5/1/2006 46 Female 99 lb 9/11/2006 Physician Japan
Primary
Concomitant
Tooth Discolouration Other Serious 1/1/2004 43 Female 147 lb 9/12/2006 Physician United States
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 5/1/2006 46 Female 99 lb 9/19/2006 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 7/8/2004 50 Female 9/21/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 59 Male 134 lb 10/2/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 10/1/2006 Female 11/6/2006 Other Health Professional United States
Primary
Concomitant
Medication Error Death 65 Male 265 lb 12/6/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 11/19/2006 65 Male 265 lb 1/19/2007 Consumer United States
Primary
Concomitant
Rectal Stenosis Hospitalization 1/11/2007 Male 1/29/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/31/2006 65 Male 265 lb 2/14/2007 Consumer United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 2/1/2007 56 Female Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 1/4/2006 49 Female 2/20/2007 Physician Japan
Primary
Secondary
Concomitant
Rectal Stenosis Hospitalization 1/11/2007 Male 4/4/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Subcutaneous Emphysema Hospitalization 5/7/2007 54 Male 190 lb 5/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious Female 5/21/2007 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 5/25/2007 51 Female 203 lb 5/30/2007 Physician United States
Primary
Concomitant
Back Pain Hospitalization 5/24/2004 66 Male 162 lb 5/26/2004 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/20/2007 Male 214 lb 6/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 42 Female 7/6/2007 Consumer United States
Primary
Concomitant
Vomiting 56 Female 7/6/2007 Consumer United States
Primary
Concomitant
Somnolence Hospitalization 4/30/2007 53 Female 166 lb 7/26/2007 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 4/26/2006 76 Male 7/24/2007 Pharmacist United States
Primary
Concomitant
Malaise Other Serious Female 8/2/2007 Consumer United States
Primary
Concomitant
Rectal Abscess Life Threatening 5/1/2007 Male 10/4/2007 Consumer United States
Primary
Concomitant
Weight Decreased 6/22/2007 39 Female 10/11/2007 Consumer United States
Primary
Concomitant
Drug Administration Error 7/1/2007 65 Female 10/11/2007 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea 8/11/2007 45 Female 10/11/2007 Consumer United States
Primary
Concomitant
Toothache Other Serious 7/4/2006 44 Female 11/1/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Toothache Other Serious 7/4/2006 44 Female 12/6/2007 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2002 68 Female 140 lb 12/18/2007 Consumer United States
Primary
Concomitant
Hyperammonaemia Other Serious 4/9/2004 58 Female 12/18/2007 Physician Japan
Primary
Concomitant
Diarrhoea 5/1/2007 65 Female 1/11/2008 Consumer United States
Primary
Concomitant
Rash Papular Hospitalization 2/8/2007 51 Female 2/1/2008 Other Health Professional United States
Primary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/13/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/17/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/17/2008 United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 10/1/1999 80 Female 3/28/2008 Other Health Professional United States
Primary
Concomitant
Nausea Death 10/7/2005 49 Female 95 lb 3/31/2008 Physician Japan
Primary
Concomitant
Large Intestine Perforation Other Serious 70 Female 3/31/2008 Physician United Kingdom
Primary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 4/4/2008 United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 4/15/2008 Female 4/30/2008 Physician United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 4/15/2008 Female 5/2/2008 Physician United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 4/15/2008 Female 5/7/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 4/28/2008 45 Female 5/9/2008 Physician Israel
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 4/15/2008 Female 5/12/2008 Physician United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 4/15/2008 Female 5/14/2008 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 5/11/2008 50 Female 183 lb 5/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sneezing 1/8/2008 Female 5/30/2008 Consumer United States
Primary
Concomitant
Jaundice Death 2/1/2007 Female 112 lb 5/30/2008 Physician Japan
Primary
Concomitant
Cognitive Disorder Hospitalization 2/27/2008 52 Female 7/2/2008 Physician France
Primary
Secondary
Concomitant
Pyrexia 5/2/2008 Female 7/3/2008 Consumer United States
Primary
Concomitant
Rash Macular 5/28/2008 55 Female 7/3/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 53 Female 214 lb 7/14/2008 Physician France
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 7/22/2008 64 Female 127 lb 7/23/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/25/2008 Female 229 lb 7/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 7/22/2008 64 Female 127 lb 8/5/2008 United States
Primary
Secondary
Concomitant
Pain In Extremity 4/15/2008 58 Female 8/6/2008 Consumer United States
Primary
Concomitant
Disease Progression Hospitalization 9/17/2008 57 Female 143 lb 9/19/2008 Other Health Professional United States
Primary
Concomitant
Product Quality Issue Hospitalization 67 10/6/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2008 Female 148 lb 10/27/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 148 lb 11/11/2008 Physician United States
Primary
Concomitant
Product Quality Issue Hospitalization 67 Female 11/19/2008 Consumer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2003 Female 194 lb 11/28/2008 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2001 Female 152 lb 11/28/2008 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/17/2008 35 Female 12/16/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/17/2008 35 Female 150 lb 12/29/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Dyskinesia Other Serious 6/1/2008 1/7/2009 Physician Japan
Primary
Concomitant
Fatigue Hospitalization 1/12/2009 Male 193 lb 1/14/2009 Consumer United States
Primary
Secondary
Concomitant
Metastases To Lung Hospitalization 1/12/2009 Male 193 lb 1/20/2009 Consumer United States
Primary
Secondary
Concomitant
Thirst Other Serious 10/1/2008 2/5/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/17/2008 35 Female 150 lb 3/6/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/17/2008 Female 150 lb 4/3/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Vomiting 2/11/2009 59 Female 194 lb 4/2/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting 3/7/2009 40 Female 4/2/2009 Consumer United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2003 Female 194 lb 4/16/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 10/17/2008 Female 5/26/2009 Other Health Professional Japan
Primary
Concomitant
Vomiting 2/11/2009 59 Female 194 lb 7/10/2009 Consumer United States
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious 8/7/2008 64 Female 7/14/2009 Other Health Professional United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/31/2009 70 Female 99 lb 8/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/2/2009 51 Female 243 lb 9/10/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 67 Female 9/14/2009 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral 7/19/2009 54 Female 9/24/2009 Consumer United States
Primary
Concomitant
Hypotension 8/5/2009 51 Female 9/24/2009 Consumer United States
Primary
Secondary
Concomitant
Toothache Other Serious 1/1/2002 Female 10/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 1/26/2008 68 10/23/2009 Physician France
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 1/26/2008 68 10/30/2009 Physician France
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious Female 176 lb 11/2/2009 Other Health Professional Sweden
Primary
Concomitant
Movement Disorder Hospitalization 6/9/2009 Female 130 lb 11/17/2009 Physician Japan
Primary
Secondary
Depressed Level Of Consciousness Hospitalization 1/1/2008 50 Female 11/20/2009 Other Health Professional Japan
Primary
Concomitant
Tongue Paralysis Hospitalization 6/9/2009 Female 130 lb 12/3/2009 Physician Japan
Primary
Secondary
Vomiting Other Serious 1/1/2008 Female 148 lb 12/1/2009 Physician United States
Primary
Concomitant
Pneumonia Death 12/1/2009 Male 121 lb 12/22/2009 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious Female 176 lb 12/30/2009 Other Health Professional Sweden
Primary
Concomitant
Pneumonia Death 12/1/2009 Male 121 lb 12/31/2009 Physician Japan
Primary
Secondary
Concomitant
Tenderness Other Serious 12/2/2009 77 Female 156 lb 1/8/2010 Consumer United States
Primary
Secondary
Concomitant
Uterine Cervical Squamous Metaplasia Other Serious 6/26/2006 49 Female 129 lb 1/11/2010 Other Health Professional United States
Primary
Concomitant
Scratch Other Serious 2/13/2001 Female 134 lb 1/11/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2003 Female 1/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Death 12/1/2009 Male 121 lb 2/1/2010 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/5/2005 Female 2/8/2010 United States
Primary
Secondary
Concomitant
Uterine Cervical Squamous Metaplasia Other Serious 6/26/2006 49 Female 129 lb 2/17/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 8/1/2003 Female 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/5/2005 Female 2/22/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/26/2006 Female 129 lb 2/26/2010 Other Health Professional United States
Primary
Concomitant
Varices Oesophageal Other Serious 2/23/2009 Female 3/4/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/26/2006 Female 129 lb 3/8/2010 Other Health Professional United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious 2/13/2001 Female 134 lb 3/9/2010 United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 2/13/2001 Female 134 lb 3/10/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/5/2005 Female 3/11/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/26/2006 Female 129 lb 3/11/2010 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 4/14/2005 Female 127 lb 3/12/2010 Physician United States
Primary
Concomitant
Varices Oesophageal Other Serious 2/23/2009 Female 3/15/2010 Physician United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 Female 3/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2003 Female 3/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/5/2005 Female 3/18/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 7/23/2004 Female 119 lb 3/19/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 6/18/2008 Female 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/12/2000 Female 134 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2003 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 1/1/2004 Female 3/26/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 9/12/2000 Female 134 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/30/2010 Physician United States
Primary
Concomitant
Toothache Other Serious 1/12/2002 Female 3/30/2010 Physician United States
Primary
Concomitant
Varices Oesophageal Other Serious 1/1/2004 Female 3/30/2010 Physician United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 Female 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2003 Female 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/5/2005 Female 3/31/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/18/2008 54 Female 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 47 Female 4/5/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 9/12/2000 65 Female 134 lb 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/26/2006 47 Female 129 lb 4/6/2010 United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 64 Female 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 5/5/2005 57 Female 4/7/2010 United States
Primary
Secondary
Concomitant
Constipation 57 Female 4/9/2010 Consumer United States
Primary
Concomitant
Rash 48 Female 4/9/2010 Consumer United States
Primary
Secondary
Concomitant
Duodenal Ulcer Perforation Hospitalization 3/14/2010 65 Female 121 lb 4/12/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 8/1/2003 43 Female 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/12/2002 54 Female 4/13/2010 Pharmacist United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 4/15/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 7/23/2004 49 Female 119 lb 4/15/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 3/2/2009 58 Female 88 lb 4/22/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/18/2008 54 Female 4/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data