Oxycontin combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Hospitalization 8/24/2005 71 Female 1/25/2006 Other Health Professional United States
Primary
Secondary
Somnolence Other Serious 12/14/2005 46 Female 110 lb 1/20/2006 United States
Primary
Concomitant
Rash Other Serious 49 Female 237 lb 2/27/2006 Consumer United States
Primary
Concomitant
Wheezing Other Serious 63 Male 3/16/2006 Pharmacist United States
Primary
Concomitant
Osteonecrosis Other Serious 11/30/2005 Female 4/28/2006 Physician Sweden
Primary
Concomitant
Wheezing Other Serious 63 Male 4/25/2006 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 9/29/2005 68 Female 196 lb 4/25/2006 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 5/18/2006 Physician Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 12/14/2005 46 Female 110 lb 4/20/2006 Physician United States
Primary
Concomitant
Vomiting Life Threatening 9/29/2005 68 Female 196 lb 7/6/2006 United States
Primary
Concomitant
Weight Increased Other Serious 76 Female 8/4/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/22/2006 64 Male 8/7/2006 Consumer Sweden
Primary
Concomitant
Vomiting Other Serious 2/1/2005 Female 130 lb 9/28/2006 Consumer United States
Primary
Concomitant
Dyspnoea 6/1/2006 80 Male 11/13/2006 Consumer United States
Primary
Concomitant
Psychotic Disorder Other Serious 9/1/2006 77 Male 121 lb 2/14/2007 Physician Sweden
Primary
Concomitant
Tremor Required Intervention 5/2/2006 65 Female 11/13/2006 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 8/18/2005 67 Male 238 lb 3/29/2007 Physician United States
Primary
Concomitant
Death Hospitalization 57 Female 8/20/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 57 Female 263 lb 8/30/2007 Other Health Professional United States
Primary
Concomitant
Drug Administration Error 7/1/2007 65 Female 10/11/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 57 Female 263 lb 10/5/2007 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization Male 1/21/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Male 345 lb 1/30/2008 Physician United States
Primary
Concomitant
Blood Testosterone Decreased Other Serious Male 3/13/2008 Physician Canada
Primary
Concomitant
Thinking Abnormal Other Serious 3/20/2008 Female 131 lb 4/2/2008 Other Health Professional United States
Primary
Concomitant
Swelling Other Serious 3/20/2008 Female 131 lb 4/28/2008 Other Health Professional United States
Primary
Concomitant
Throat Tightness Other Serious 3/20/2008 Female 131 lb 5/30/2008 Physician United States
Primary
Concomitant
Throat Tightness Other Serious 3/20/2008 Female 131 lb 7/11/2008 Physician United States
Primary
Concomitant
Transaminases Increased Hospitalization 6/19/2008 31 Female 198 lb 7/17/2008 Physician United States
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 7/30/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pain Life Threatening 10/18/2006 47 Female 88 lb 8/8/2008 Physician Japan
Primary
Concomitant
Circulatory Collapse Other Serious 8/6/2008 61 Female 8/12/2008 Other Health Professional France
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 8/6/2008 61 Female 8/19/2008 Other Health Professional France
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 8/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 9/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/19/2008 Male 184 lb 10/13/2008 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 10/29/2008 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 10/13/2008 53 Male 170 lb 10/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 12/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 12/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 12/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 12/31/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 2/19/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 3/9/2009 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Disability 10/1/2008 66 Female 151 lb 3/17/2009 Physician United States
Primary
Concomitant
Somnolence Hospitalization Female 3/24/2009 Other Health Professional France
Primary
Secondary
Pulmonary Embolism Other Serious 2/1/2009 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 4/10/2009 Physician United States
Primary
Secondary
Concomitant
Insomnia 3/18/2009 78 Female 170 lb 5/15/2009 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 2/1/2009 Female 5/20/2009 Physician United States
Primary
Concomitant
Interacting
Tooth Extraction Other Serious 2/1/1998 Male 5/20/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 2/1/2009 Female 6/1/2009 Physician United States
Primary
Concomitant
Interacting
Ascites Hospitalization 5/30/2008 Male 6/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 6/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 75 6/9/2009 Australia
Primary
Concomitant
Headache Other Serious 6/1/2009 Female 280 lb 6/30/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 2/1/2009 Female 7/2/2009 Physician United States
Primary
Concomitant
Interacting
Weight Decreased Other Serious 4/1/2009 Male 213 lb 7/8/2009 Physician United States
Primary
Concomitant
Headache Other Serious 6/1/2009 Female 280 lb 7/16/2009 Consumer United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 75 7/24/2009 Australia
Primary
Concomitant
Vomiting Female 120 lb 7/24/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Staphylococcal Hospitalization 5/1/2008 69 Female 9/11/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/7/2008 53 Male 243 lb 9/14/2009 United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 9/7/2008 53 Male 9/28/2009 United States
Primary
Concomitant
Headache Other Serious 6/1/2009 Female 280 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 5/5/2009 75 Female 154 lb 9/29/2009 Netherlands
Primary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Splenomegaly Other Serious 4/4/2008 Male 268 lb 11/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 11/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 11/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/1/2009 70 Female 11/12/2009 Physician New Zealand
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 5/1/2008 69 Female 11/18/2009 Other Health Professional United States
Primary
Concomitant
Renal Impairment Life Threatening 8/26/2009 71 Male 128 lb 11/24/2009 Physician Japan
Primary
Concomitant
Palpitations Disability 10/1/2008 66 Female 151 lb 11/24/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Male 345 lb 11/30/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 9/19/2008 Male 184 lb 12/1/2009 Physician United States
Primary
Concomitant
Somnolence Hospitalization 12/1/2008 59 Female 200 lb 12/18/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 68 Male 1/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Hospitalization 12/1/2008 58 Female 200 lb 1/6/2010 Physician United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 11/1/2009 1/14/2010 Consumer United States
Primary
Concomitant
Spleen Scan Abnormal Hospitalization 11/1/2009 1/22/2010 Consumer United States
Primary
Concomitant
Spleen Scan Abnormal Hospitalization 11/1/2009 1/24/2010 Consumer United States
Primary
Concomitant
Spleen Scan Abnormal Hospitalization 11/1/2009 1/29/2010 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 74 Male 2/5/2010 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 74 Male 2/5/2010 United States
Primary
Concomitant
Pulmonary Congestion 1/1/2010 68 Female 280 lb 3/31/2010 Physician United States
Primary
Concomitant
Spleen Scan Abnormal Hospitalization 11/1/2009 4/12/2010 Consumer United States
Primary
Concomitant
Muscular Weakness Hospitalization 4/5/2010 64 Male 200 lb 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venous Insufficiency Other Serious 2/1/1998 60 Male 4/19/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/11/2009 47 Male 185 lb 4/14/2010 United States
Primary
Secondary
Concomitant
Disease Progression Death 4/19/2010 65 Male 200 lb 4/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization Female 5/4/2010 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 3/16/2010 55 Female 160 lb 5/6/2010 Physician United States
Primary
Concomitant
Venous Insufficiency Other Serious 2/1/1998 60 Male 5/7/2010 United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 8/1/2009 75 Female 5/18/2010 Consumer Netherlands
Primary
Concomitant
Venous Insufficiency Other Serious 2/1/1998 60 Male 5/21/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 2/1/1998 60 Male 5/25/2010 United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/18/2010 71 Female 6/1/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Abnormal Hospitalization 11/1/2009 6/9/2010 Consumer United States
Primary
Concomitant
Sepsis Death 11/18/2009 65 Female 93 lb 6/23/2010 Physician Japan
Primary
Concomitant
Pancreatitis Hospitalization Female 6/24/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/1/2009 6/25/2010 Consumer United States
Primary
Concomitant
Transplant Rejection Hospitalization Female 126 lb 6/28/2010 Physician United States
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 7/13/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Vision Blurred Other Serious 2/1/1998 60 Male 7/20/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/14/2004 58 Female 155 lb 7/23/2010 United States
Primary
Secondary
Concomitant
Nausea 4/1/2009 53 Female 115 lb 7/23/2010 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 7/11/2010 55 Female 234 lb 7/28/2010 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 6/1/2010 43 Male 290 lb 8/10/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 7/12/2010 64 Male 8/10/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/14/2004 58 Female 155 lb 8/24/2010 United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/1/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 4/30/2010 32 Female 9/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 60 Male 9/9/2010 United States
Primary
Secondary
Concomitant
Sepsis Death 11/18/2009 65 Female 93 lb 9/15/2010 Physician Japan
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pancreatitis Hospitalization Female 9/16/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2010 52 Female 148 lb 9/22/2010 Physician United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 8/26/2009 71 Male 128 lb 9/23/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 6/14/2004 58 Female 155 lb 9/23/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 60 Male 9/24/2010 United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/28/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 60 Male 10/5/2010 United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 6/1/2010 43 Male 290 lb 10/6/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 6/14/2004 58 Female 155 lb 10/6/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 60 Male 10/8/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 60 Male 10/14/2010 United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 10/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 10/2/2010 11/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 60 Male 11/10/2010 United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/28/2010 69 Male 11/11/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 5/1/2010 63 Male 11/15/2010 Consumer United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 52 Male 11/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/14/2004 58 Female 155 lb 11/30/2010 United States
Primary
Secondary
Concomitant
Oropharyngeal Spasm Other Serious 1/1/2009 45 Male 280 lb 12/10/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 6/14/2004 58 Female 155 lb 12/13/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 60 Male 12/14/2010 United States
Primary
Secondary
Concomitant
Drug Dependence Other Serious 1/1/2010 52 Female 12/14/2010 Pharmacist Canada
Primary
Secondary
Concomitant
Splenomegaly Other Serious 4/4/2008 67 Male 268 lb 12/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 5/30/2008 67 Male 12/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Skin Infection Hospitalization 9/17/2010 59 Male 12/23/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 6/1/2010 44 Male 290 lb 11/8/2010 Consumer United States
Primary
Concomitant
Drug Administration Error Hospitalization 9/17/2010 59 Male 1/4/2011 Consumer Australia
Primary
Secondary
Concomitant
Glossodynia 7/1/2010 51 Female 1/29/2011 Consumer United States
Primary
Concomitant
Oral Herpes 1/1/2010 72 Female 151 lb 1/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 11/8/2010 64 Female 1/30/2011 Consumer United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 6/14/2004 58 Female 155 lb 1/31/2011 United States
Primary
Secondary
Concomitant
Arterial Thrombosis Limb Life Threatening 8/26/2009 71 Male 128 lb 2/14/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 6/14/2004 58 Female 155 lb 2/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data