Oxcarbazepine combined with Topiramate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Disorder Life Threatening 15 Female 2/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Serotonin Syndrome Death 39 Female 2/7/2006 Pharmacist United States
Primary
Secondary
Psychotic Disorder Hospitalization 12/2/2004 56 Male 158 lb 1/14/2006 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening 15 Female 3/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 10/1/2002 54 Female 135 lb 10/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 75 Female 3/10/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 3/20/2007 Physician Germany
Primary
Secondary
Aphasia Other Serious 39 Male 4/13/2007 Italy
Primary
Concomitant
Suicidal Ideation Hospitalization 35 Female 5/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 35 Female 6/1/2007 United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 5/28/2007 8 Male 7/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 75 Female 8/22/2007
Primary
Secondary
Concomitant
Traumatic Brain Injury Other Serious 6/1/2006 62 Male 231 lb 11/10/2007 Physician Germany
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 50 Female 3/17/2008 Other Health Professional Belgium
Primary
Secondary
Trigeminal Nerve Disorder Hospitalization 39 Female 6/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 7/9/2008 Other Health Professional Netherlands
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 7/9/2008 Other Health Professional Australia
Primary
Secondary
Stillbirth Other Serious Female 7/9/2008 Physician Italy
Primary
Secondary
Thyroxine Free Decreased Other Serious 8 Female 7/30/2008 Other Health Professional United States
Primary
Concomitant
Poisoning Life Threatening 10/1/2004 67 Male 10/28/2008 Physician Mexico
Primary
Concomitant
Normal Newborn Other Serious Female 11/10/2008 Other Health Professional Norway
Primary
Secondary
Simple Partial Seizures Other Serious Female 11/11/2008 Other Health Professional Norway
Primary
Secondary
Simple Partial Seizures Other Serious Female 11/26/2008 Other Health Professional Norway
Primary
Secondary
Vomiting Other Serious Female 1/21/2009 Other Health Professional Germany
Primary
Concomitant
Fall Other Serious 1/29/2009 62 Male 1/30/2009 Physician Germany
Primary
Concomitant
Drug Interaction 17 3/4/2009 Physician United States
Primary
Interacting
Vision Blurred Hospitalization 1/3/2007 57 Male 143 lb 3/30/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Vomiting Other Serious 12/16/2008 Female 4/7/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 3/25/2009 Female 5/28/2009 Consumer Germany
Primary
Concomitant
Metabolic Acidosis Required Intervention 5/21/2009 32 Female 6/2/2009 Other Health Professional United States
Primary
Concomitant
Psychotic Disorder Hospitalization 32 Female 6/22/2009 Other Health Professional Greece
Primary
Secondary
Psychotic Disorder Other Serious 36 Female 6/23/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Death Death 6/10/2009 59 Female 157 lb 6/24/2009 Physician United States
Primary
Concomitant
Medication Residue 4/1/2008 Female 9/15/2009 Pharmacist United States
Primary
Concomitant
Sudden Unexplained Death In Epilepsy Death 15 Male 9/18/2009 Other Health Professional Brazil
Primary
Concomitant
Normal Newborn Other Serious Female 9/22/2009 Norway
Primary
Secondary
Simple Partial Seizures Other Serious Female 9/22/2009 Other Health Professional Norway
Primary
Secondary
Craniofacial Dysostosis Other Serious Female 10/2/2009 France
Primary
Concomitant
Retrognathia Congenital Anomaly Female 10/8/2009 Other Health Professional France
Primary
Secondary
Concomitant
Teratogenicity Other Serious 25 Female 10/13/2009
Primary
Secondary
Teratogenicity Other Serious Female 10/13/2009
Primary
Secondary
Psychotic Disorder Other Serious 22 Female 10/14/2009 Physician France
Primary
Secondary
Multiple Congenital Abnormalities Congenital Anomaly Female 10/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pregnancy Other Serious Female 10/16/2009 Other Health Professional Norway
Primary
Concomitant
Retrognathia Other Serious Female 10/22/2009 France
Primary
Secondary
Concomitant
Craniofacial Dysostosis Other Serious Female 11/13/2009 France
Primary
Concomitant
Retrognathia Congenital Anomaly Female 8 lb 11/16/2009 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 16 Male 11/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatic Enzymes Increased Other Serious 45 Female 12/7/2009
Primary
Secondary
Nausea 7/25/2009 Female 225 lb 11/19/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 45 Female 12/11/2009 Physician United States
Primary
Concomitant
Lipase Increased Hospitalization 45 Female 12/24/2009 Physician United States
Primary
Concomitant
Simple Partial Seizures Other Serious 1/1/2009 Female 1/22/2010 Other Health Professional Norway
Primary
Secondary
Simple Partial Seizures Other Serious Female 1/25/2010 Other Health Professional Norway
Primary
Secondary
Convulsion Hospitalization 5/1/2009 Female 225 lb 1/26/2010 United States
Primary
Concomitant
Convulsion Other Serious 1/1/2009 Female 2/24/2010 Other Health Professional Norway
Primary
Secondary
Vomiting 7/1/2009 39 Female 115 lb 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10 Male 3/5/2010 Other Health Professional France
Primary
Concomitant
Interacting
Drug Toxicity Hospitalization 10 Male 3/12/2010 France
Primary
Concomitant
Interacting
Therapeutic Agent Toxicity Hospitalization 10 Male 3/17/2010 France
Primary
Concomitant
Interacting
Retrognathia Other Serious Female 8 lb 3/18/2010 Other Health Professional France
Primary
Secondary
Pancreatic Enzymes Increased Other Serious 15 Female 3/29/2010 Physician United States
Primary
Secondary
Metabolic Acidosis Other Serious 9 Female 4/7/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10 Male 4/14/2010 Other Health Professional France
Primary
Concomitant
Interacting
Vomiting Hospitalization 10 Male 4/19/2010 Physician France
Primary
Secondary
Vomiting Hospitalization 10 Male 4/20/2010 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 10 Male 4/20/2010 France
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 10 Male 4/23/2010
Primary
Secondary
Metabolic Acidosis Hospitalization 9 Female 4/26/2010
Primary
Secondary
Concomitant
Vomiting Hospitalization 10 Male 4/27/2010 Other Health Professional France
Primary
Concomitant
Interacting
Stevens-johnson Syndrome Life Threatening 4/1/2010 48 Male 195 lb 4/22/2010 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 10 Male 5/4/2010 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 36 Male 5/7/2010
Primary
Secondary
Treatment Failure Disability 2/24/2010 38 Female 213 lb 5/5/2010 Pharmacist United States
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 9 Female 5/8/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 36 Male 5/18/2010
Primary
Secondary
Psychotic Disorder Hospitalization 4/27/2010 14 Female 6/7/2010 United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious Female 6/24/2010 Physician United States
Primary
Secondary
Nephrolithiasis Other Serious 29 Female 6/29/2010 Other Health Professional Italy
Primary
Secondary
Haemangioma Congenital Anomaly Female 5 lb 6/29/2010 Other Health Professional Italy
Primary
Secondary
Speech Disorder Hospitalization 29 Female 7/8/2010 Italy
Primary
Secondary
Pancreatitis Other Serious 20 Female 7/19/2010 Other Health Professional Finland
Primary
Concomitant
Pancreatitis Other Serious 20 Female 8/9/2010 Other Health Professional Finland
Primary
Concomitant
Pancreatitis Acute Other Serious 15 Female 8/17/2010 Physician United States
Primary
Secondary
Pancreatitis Acute Other Serious 15 Female 8/17/2010 Physician United States
Primary
Secondary
Weight Increased Hospitalization 16 Male 9/29/2010 Physician United States
Primary
Secondary
Concomitant
Retrognathia Other Serious 25 Female 8 lb 10/27/2010 Other Health Professional France
Primary
Secondary
Pancreatitis Acute Other Serious 15 Female 11/10/2010 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2009 37 Female 1/10/2011 Physician United States
Primary
Secondary
Fall Hospitalization 67 Female 1/12/2011 Physician United States
Primary
Concomitant
Interacting
Cardiac Arrest Death 37 Female 1/12/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 37 Female 1/12/2011
Primary
Secondary
Overdose Death 37 Female 1/13/2011 Physician United States
Primary
Secondary
Completed Suicide Death 37 Female 1/19/2011 Physician United States
Primary
Secondary
Completed Suicide Death 37 Female 1/21/2011 Physician United States
Primary
Secondary
Hyperventilation Other Serious 36 Female 1/17/2011 Other Health Professional Switzerland
Primary
Concomitant
Asphyxia Death 35 Female 2/1/2011 Other Health Professional United States
Primary
Secondary
Gait Disturbance Hospitalization 10 Male 2/4/2011 Physician France
Primary
Secondary
Multiple Drug Overdose Intentional Death 37 Female 1/27/2011 Physician United States
Primary
Secondary
Bipolar I Disorder Hospitalization 67 Female 1/24/2011 Physician United States
Primary
Secondary
Concomitant
Poisoning Death 1/1/2009 37 Female 1/27/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2009 37 Female 1/25/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 1/1/2009 37 Female 1/25/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 37 Female 2/2/2011 United States
Primary
Secondary
Speech Disorder Other Serious 21 Female 2/2/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 21 Female 2/4/2011 United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization Female 134 lb Physician United States
Primary
Concomitant
Cerebral Haemorrhage Death 2/18/2011 37 Male 2/28/2011 Physician Italy
Primary
Secondary
Concomitant
Convulsion Hospitalization 36 Female 3/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Arrest Death 1/1/2009 37 Female 2/23/2011 Physician United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 37 Female 3/9/2011 Other Health Professional United States
Primary
Secondary
Fall Hospitalization Female 134 lb 2/25/2011 Physician United States
Primary
Concomitant
Diplopia Other Serious 36 Female 3/9/2011 Consumer United Kingdom
Primary
Secondary
Drug Interaction Other Serious 36 Female 3/9/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Diplopia Hospitalization 36 Female 3/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Inhibitory Drug Interaction Other Serious 36 Female 3/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Psychotic Disorder Other Serious 1/1/2009 39 Male 3/7/2011 Physician Germany
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 36 Female 3/17/2011 Consumer United Kingdom
Primary
Secondary
Physical Assault Other Serious 52 Female 3/18/2011 Physician United States
Primary
Secondary
Balance Disorder Other Serious 36 Female 3/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Psychomotor Hyperactivity Other Serious 34 Male 3/21/2011 Other Health Professional Brazil
Primary
Secondary
Drug Interaction Hospitalization 16 Male 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 37 Female 3/24/2011 Physician United States
Primary
Secondary
Anticonvulsant Drug Level Decreased Hospitalization 36 Female 3/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Balance Disorder Other Serious 37 Female 3/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 36 Female 4/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Condition Aggravated Other Serious 36 Female 3/25/2011 United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 36 Female 4/14/2011 Physician United Kingdom
Primary
Interacting
Convulsion Hospitalization 36 Female 4/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Visual Acuity Reduced Disability 1/1/2011 35 Male 4/18/2011 Physician Germany
Primary
Secondary
Concomitant
Neurotoxicity Hospitalization 36 Female 4/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Interaction Other Serious 36 Female 4/15/2011 Other Health Professional
Primary
Secondary
Anticonvulsant Drug Level Decreased Hospitalization 36 Female 4/15/2011
Primary
Secondary
Hyperammonaemic Encephalopathy Other Serious 34 Female 4/28/2011 Other Health Professional Turkey
Primary
Secondary
Toxicity To Various Agents Hospitalization 67 Female 4/29/2011 Physician United States
Primary
Concomitant
Interacting
Toxicity To Various Agents Other Serious 67 Female 5/2/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Toxicity To Various Agents Other Serious 67 Female 5/6/2011 Other Health Professional United States
Primary
Secondary
Cervical Vertebral Fracture Hospitalization 2/9/2011 27 Female 140 lb 5/6/2011 Physician United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 5/7/2011 27 Female 140 lb 5/16/2011 Physician United States
Primary
Concomitant
Hyperprolactinaemia Other Serious 3/25/2011 27 Female 5/23/2011 Pharmacist United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 34 Female 6/6/2011 Other Health Professional Turkey
Primary
Secondary
Drug Level Increased Other Serious 67 Female 5/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Convulsion Other Serious 11/1/2010 50 Male 6/20/2011 Physician Germany
Primary
Secondary
Concomitant
Death Death 11/11/2010 31 Female 6/22/2011 Other Health Professional United States
Primary
Concomitant
Altered State Of Consciousness Other Serious 34 Female 6/23/2011 Other Health Professional Turkey
Primary
Secondary
Toxicity To Various Agents Hospitalization 67 Female 7/29/2011 Other Health Professional United States
Primary
Secondary
Drug Interaction Other Serious 67 Female 8/5/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Vomiting Hospitalization 1/14/2011 20 Male 165 lb 8/11/2011 Consumer United States
Primary
Concomitant
Convulsion Other Serious 11/1/2010 50 Male 8/16/2011 Physician Germany
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 1/1/2010 49 Male 143 lb 8/16/2011 Physician Germany
Primary
Secondary
Concomitant

Drug Data