Omeprazole combined with Valproic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Therapeutic Agent Toxicity Life Threatening 8/15/2005 40 Female 1/31/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Sedation Life Threatening 6/15/2005 40 Female 1/31/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypertriglyceridaemia Hospitalization 4/27/2005 53 Female 4/17/2006 Mexico
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 40 Male 6/21/2006 Other Health Professional Australia
Primary
Secondary
Pharmaceutical Product Complaint 8/24/2005 60 Female 7/12/2006 Consumer United States
Primary
Concomitant
Parkinsonism Hospitalization 10/28/2004 77 Female 140 lb 7/28/2006 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/27/2006 77 Male Pharmacist United States
Primary
Concomitant
Postictal State Other Serious 7/13/2006 42 Female 1/3/2007 United Kingdom
Primary
Concomitant
Drug Level Decreased Other Serious 1/3/2006 80 Female 163 lb 3/23/2007 France
Primary
Secondary
Concomitant
Interacting
Tracheostomy Other Serious 43 Male 5/7/2007 Physician Brazil
Primary
Secondary
Concomitant
Confusional State Hospitalization 9/29/2006 51 Female 3/14/2007 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 63 Female 7/11/2007
Primary
Secondary
Hodgkin's Disease Other Serious 4/1/2007 Female 134 lb 7/24/2007 Consumer Mexico
Primary
Concomitant
Transplant Rejection Life Threatening 6/13/2007 57 Female 7/25/2007 United Kingdom
Primary
Concomitant
Transplant Rejection Life Threatening 6/13/2007 57 Female 8/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 8/6/2007 Male 112 lb 8/20/2007 Pharmacist United States
Primary
Concomitant
Weight Increased 52 Female 227 lb 9/18/2007 Consumer United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 8/6/2007 42 Male 112 lb 10/24/2007 Pharmacist United States
Primary
Concomitant
Suicide Attempt Other Serious 1/25/2008 50 Male 2/6/2008 Physician Brazil
Primary
Secondary
Raynaud's Phenomenon Other Serious 1/1/2001 Female 137 lb 2/8/2008 Netherlands
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 1/21/2008 52 Female 143 lb 2/18/2008 Physician Israel
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 62 Female 2/20/2008 Netherlands
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 62 Female 2/22/2008 France
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 62 Female 2/22/2008 France
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 1/21/2008 52 Female 143 lb 2/29/2008 Physician Israel
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 62 Female 3/14/2008 Netherlands
Primary
Concomitant
Epilepsy Other Serious 1/14/2008 53 Male 4/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Death 9/11/2004 Female 125 lb 4/10/2008 Lawyer United States
Primary
Concomitant
Swollen Tongue Hospitalization 3/23/2008 Female 143 lb 4/30/2008 Pharmacist United States
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 62 Female 6/12/2008 France
Primary
Concomitant
Transaminases Increased Other Serious 10/10/2003 Female 6/13/2008 France
Primary
Concomitant
Somnolence Other Serious Female 6/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious Female 7/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Death 9/11/2004 Female 125 lb 7/22/2008 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious Female 7/15/2008 United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 8/5/2008 91 Female 132 lb 9/2/2008 Other Health Professional Portugal
Primary
Concomitant
Interacting
Drug Interaction Other Serious 8/5/2008 91 Female 132 lb 9/23/2008 Other Health Professional Portugal
Primary
Concomitant
Interacting
Drug Toxicity Death 9/11/2004 Female 125 lb 10/17/2008 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 60 Female 10/27/2008 Physician Portugal
Primary
Secondary
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Death Death 8/16/2008 Female 287 lb 11/14/2008 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death 8/15/2008 Female 287 lb 11/24/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2008 69 Female 130 lb 11/21/2008 Portugal
Primary
Secondary
Concomitant
Chest Pain Hospitalization 11/12/2008 60 Female 11/26/2008 Consumer Colombia
Primary
Concomitant
Chest Pain Hospitalization 11/12/2008 60 Female 12/2/2008 Consumer Colombia
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death 8/15/2008 Female 287 lb 12/22/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2008 69 Female 130 lb 1/13/2009 Portugal
Primary
Secondary
Concomitant
Drug Toxicity Death 9/11/2004 Female 125 lb 1/26/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 32 Male 227 lb 1/26/2009 Germany
Primary
Concomitant
Interacting
Urinary Incontinence Life Threatening 9/15/2008 70 Male 2/23/2009 Pharmacist Switzerland
Primary
Concomitant
Interacting
Urinary Incontinence Life Threatening 9/15/2008 70 Male 2/27/2009 Pharmacist Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 59 Female 3/9/2009 Netherlands
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/27/2009 56 Male 130 lb 3/20/2009 Physician Germany
Primary
Secondary
Concomitant
Urinary Incontinence Life Threatening 9/15/2008 70 Male 4/6/2009 Pharmacist Switzerland
Primary
Concomitant
Interacting
Urinary Incontinence Life Threatening 9/15/2008 70 Male 4/10/2009 Pharmacist Switzerland
Primary
Secondary
Concomitant
Drug Toxicity Death 9/11/2004 Female 125 lb 4/17/2009 Other Health Professional United States
Primary
Concomitant
Convulsion Hospitalization 4/18/2009 5/5/2009 Physician Argentina
Primary
Concomitant
Convulsion Hospitalization 4/15/2009 59 5/8/2009 Physician Argentina
Primary
Concomitant
Convulsion Hospitalization 4/15/2009 59 5/25/2009 Physician Argentina
Primary
Concomitant
Urticaria Hospitalization 38 Male 5/21/2009 Physician Germany
Primary
Secondary
Decreased Appetite Hospitalization 4/15/2009 59 7/2/2009 Physician Argentina
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death 8/15/2008 Female 287 lb 7/13/2009 Physician United States
Primary
Concomitant
Subileus Death 1/11/2009 68 Female 117 lb 7/29/2009 Physician Germany
Primary
Secondary
Vomiting Other Serious 2/16/2009 Male 7/30/2009 Physician United States
Primary
Secondary
Concomitant
Subileus Death 1/11/2009 68 Female 117 lb 7/27/2009 Physician Germany
Primary
Secondary
International Normalised Ratio Increased Hospitalization 56 Male 124 lb 8/5/2009 Pharmacist United States
Primary
Concomitant
Interacting
Renal Tubular Necrosis Hospitalization 4/14/2009 72 Male 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/6/2003 43 Male 213 lb 8/7/2009 United States
Primary
Concomitant
Decreased Appetite Hospitalization 4/15/2009 59 8/7/2009 Physician Argentina
Primary
Concomitant
Subileus Death 1/11/2009 68 Female 8/10/2009 Physician France
Primary
Secondary
Vomiting Other Serious 2/16/2009 Male 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Subileus Other Serious 1/11/2009 68 Female 117 lb 10/12/2009 Pharmacist Germany
Primary
Secondary
Meningioma Hospitalization 9/15/2007 Male 10/13/2009 Other Health Professional France
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 7/31/2009 52 Male 10/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Subileus Other Serious 1/1/2009 68 Female 117 lb 10/19/2009 Pharmacist United States
Primary
Secondary
Ileus Hospitalization 1/9/2009 Female 10/23/2009 Physician France
Primary
Secondary
Concomitant
Meningioma Hospitalization 9/15/2007 Male 10/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Syncope Other Serious 56 Male 123 lb 10/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Decreased Appetite Hospitalization 4/15/2009 59 10/28/2009 Physician Argentina
Primary
Concomitant
Syncope Hospitalization 56 Male 124 lb 10/29/2009 Pharmacist United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Required Intervention Male 124 lb 10/23/2009 Pharmacist United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 4/15/2009 59 Male 143 lb 11/27/2009 Physician Argentina
Primary
Concomitant
Decreased Appetite Hospitalization 4/15/2009 59 Male 143 lb 12/4/2009 Other Health Professional Argentina
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 56 Male 124 lb 12/7/2009 Pharmacist United States
Primary
Secondary
Concomitant
Platelet Count Decreased Disability 4/15/2009 50 Female 157 lb 12/10/2009 Pharmacist United States
Primary
Concomitant
Weight Increased 7/16/2009 51 Male 209 lb 12/9/2009 Consumer United States
Primary
Concomitant
Syncope Other Serious 56 Male 123 lb 1/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Medication Error Male 1/20/2010 Consumer United States
Primary
Concomitant
Serum Ferritin Increased Other Serious 1/6/2010 49 Male 152 lb 1/22/2010 Physician Belgium
Primary
Concomitant
Meningioma Hospitalization 9/1/2007 Male 185 lb 2/2/2010 Other Health Professional France
Primary
Secondary
Concomitant
Skin Burning Sensation 2/5/2010 Female 187 lb 2/16/2010 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 2/16/2010 50 Female 234 lb 3/17/2010 Pharmacist United States
Primary
Concomitant
Hepatitis Toxic Other Serious 1/6/2010 49 Male 152 lb 4/2/2010 Physician Belgium
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 4/14/2010 United States
Primary
Secondary
Concomitant
Mental Disorder Other Serious 62 Female 4/19/2010 Consumer Colombia
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 47 Male 5/27/2010 Physician United States
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 1/16/2004 59 Male 6/11/2010 United States
Primary
Concomitant
Vomiting Other Serious 3/1/2009 19 Female 6/14/2010 Consumer United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 4/15/2009 59 Male 143 lb 6/14/2010 Other Health Professional Argentina
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 6/21/2010 United States
Primary
Secondary
Concomitant
Osteopenia Hospitalization 2/2/2010 42 Male 223 lb 6/22/2010 Physician Germany
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 1/16/2004 59 Male 7/14/2010 United States
Primary
Concomitant
Osteopenia Hospitalization 2/2/2010 42 Male 223 lb 7/16/2010 Physician Germany
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2009 49 Male 235 lb 5/18/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 7/29/2010 United States
Primary
Secondary
Concomitant
Mental Disorder Other Serious 62 Female 8/17/2010 Consumer Colombia
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 8/23/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 8/26/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Male 9/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Osteopenia Hospitalization 2/2/2010 42 Male 223 lb 9/14/2010 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Chronic Other Serious 1/1/2005 56 Male 187 lb 9/17/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious Male 11/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Sedation Hospitalization 8/17/2010 55 Male 111 lb 11/3/2010 Pharmacist United States
Primary
Concomitant
Neck Mass Other Serious 11/1/2010 40 Female 128 lb 12/23/2010 Consumer Canada
Primary
Concomitant
Neoplasm Malignant Hospitalization 11/1/2010 40 Female 128 lb 1/3/2011 Consumer Canada
Primary
Concomitant
Cardio-respiratory Arrest Death 10 Male 1/4/2011 Other Health Professional United States
Primary
Secondary
Injury Death 1/1/2009 10 Male 1/6/2011 Physician United States
Primary
Secondary
Intentional Drug Misuse Hospitalization 10 Male 1/12/2011 Physician United States
Primary
Secondary
Syncope Hospitalization 6/1/2010 39 Female 150 lb 12/30/2010 Physician Germany
Primary
Secondary
Concomitant
Heart Rate Decreased Other Serious 6/1/2010 39 Female 150 lb 1/7/2011 Other Health Professional Germany
Primary
Concomitant
Cardio-respiratory Arrest Death 10 Male 1/21/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Other Serious 10 Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 1/1/2009 10 Male 1/26/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 10 Male 1/20/2011 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2009 10 Male 1/26/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 10 Male 3/7/2011 Other Health Professional United States
Primary
Secondary
Death Death 10 Male 2/25/2011 Physician United States
Primary
Concomitant
Child Abuse Death 10 Male 3/14/2011 Physician United States
Primary
Secondary
Generalised Oedema Hospitalization 1/23/2011 30 Male 156 lb 3/17/2011 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Death 10 Male 3/24/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 10 Male 3/30/2011 Other Health Professional United States
Primary
Secondary
Serum Ferritin Increased Hospitalization 2/16/2009 72 Male 5/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Anaemia Hospitalization 4/14/2009 72 Male 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 6/9/2004 71 Male 6/8/2011 Other Health Professional Canada
Primary
Concomitant
Obesity Death 1/18/2008 49 Male 6/4/2011 Physician United Kingdom
Primary
Concomitant
Hepatitis C Virus Test Positive Death Male 6/14/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Haematochezia Hospitalization 11/8/2008 69 Male 140 lb 6/14/2011 Consumer United States
Primary
Concomitant
Gastric Polyps Other Serious 9/15/2008 69 Male 6/8/2011 Consumer United States
Primary
Secondary
Concomitant
Hypoventilation Hospitalization 11/1/2010 74 Male 6/24/2011 Other Health Professional Netherlands
Primary
Concomitant
Pruritus Other Serious 5/29/2010 46 Female 6/23/2011 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/7/2004 60 Male 7/5/2011 Consumer United States
Primary
Concomitant
Asthenia Hospitalization 11/8/2008 69 Male 140 lb 7/7/2011 Consumer United States
Primary
Secondary
Concomitant
Herpes Virus Infection Other Serious 12/1/2010 16 Female 88 lb 7/14/2011 Consumer Brazil
Primary
Concomitant
Hypothermia Hospitalization 5/3/2011 64 Male 9/2/2011 Physician France
Primary
Concomitant
Bipolar Disorder Hospitalization 4/1/2011 50 Male 9/9/2011 Consumer Brazil
Primary
Concomitant
Ejection Fraction Decreased Disability 5/31/2011 25 Male 9/17/2011 Pharmacist United States
Primary
Secondary
Concomitant
Insomnia Other Serious 8/26/2011 51 Male 9/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Epilepsy Other Serious 51 Male 9/21/2011 Physician United Kingdom
Primary
Concomitant
Insomnia Other Serious 52 Male 9/22/2011 United Kingdom
Primary
Concomitant
Drug Dose Omission Other Serious 2/1/2011 86 Male 10/18/2011 Consumer United Kingdom
Primary
Concomitant

Drug Data