Omeprazole combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Ulcer Hospitalization 10/10/2003 57 Male 160 lb 1/5/2006 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/21/2005 65 Female 106 lb 1/13/2006 Netherlands
Primary
Concomitant
Haemothorax Life Threatening 8/17/2004 77 Male 1/20/2006 Consumer Poland
Primary
Concomitant
Platelet Count Decreased Other Serious 11/4/2005 72 Female 97 lb 1/18/2006 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 1/7/2006 74 Male 1/18/2006 Other Health Professional United States
Primary
Concomitant
Spleen Disorder Other Serious 2/25/2005 66 Male 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ascites Hospitalization 6/16/2005 Female 1/26/2006 United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization 1/10/2006 58 Male 1/30/2006 Physician United States
Primary
Concomitant
Lethargy Other Serious 12/27/2005 64 Female 253 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Somnolence Life Threatening 11/21/2005 85 Female 143 lb 1/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/3/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Tremor Hospitalization 12/7/2005 74 Male 213 lb 12/29/2005 Pharmacist United States
Primary
Concomitant
Ventricular Asystole Death 7/15/2004 68 Female 128 lb 2/9/2006 Physician Brazil
Primary
Concomitant
Hyperkalaemia Hospitalization 12/2/2005 61 Male Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 52 Male 2/15/2006 Consumer United States
Primary
Secondary
Concomitant
Restrictive Pulmonary Disease Hospitalization 52 Male 2/10/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 9/5/2005 33 Male 2/13/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 12/20/2005 74 Male 187 lb 2/16/2006 Czech Republic
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 1/18/2006 85 Male 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Shock Other Serious 11/4/2005 72 Female 97 lb 2/23/2006 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Life Threatening 2/3/2006 53 Male 159 lb 2/17/2006 Consumer Colombia
Primary
Secondary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 64 Male 2/28/2006 Israel
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/22/2006 69 Female 3/10/2006 Physician Sweden
Primary
Concomitant
Neutropenia Life Threatening 2/3/2006 53 Male 159 lb 2/24/2006 Consumer Colombia
Primary
Secondary
Concomitant
Ascites Hospitalization 6/16/2005 Female 3/13/2006 United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Required Intervention 3/6/2006 79 Male 184 lb 3/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 3/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/1/2003 67 Female 174 lb 3/7/2006 Lawyer United States
Primary
Concomitant
Influenza Hospitalization 80 Female 3/14/2006 United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 6/16/2005 Female 3/23/2006 United Kingdom
Primary
Secondary
Concomitant
Throat Tightness Hospitalization 9/15/2005 49 Female 3/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Viral Mutation Identified Hospitalization 6/16/2005 Female 3/29/2006 United Kingdom
Primary
Secondary
Concomitant
Virus Serology Test Positive Other Serious 2/23/2005 57 Male 3/16/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 2/16/2006 80 Female 3/29/2006
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 12/5/2005 55 Male 4/6/2006 Other Health Professional France
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 12/5/2005 55 Male 4/10/2006 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 4/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toothache Other Serious 12/1/2005 67 Female 139 lb 4/13/2006 Physician Portugal
Primary
Concomitant
Neutropenia Hospitalization 52 Male 4/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/16/2006 81 Female 4/13/2006 Czech Republic
Primary
Secondary
Concomitant
Encephalopathy Other Serious 2/22/2006 79 Male 4/13/2006 Pharmacist Spain
Primary
Secondary
Concomitant
Urticaria Other Serious 1/2/2006 67 Male 248 lb 2/15/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 4/13/2006 76 Male 160 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 4/19/2006 Physician France
Primary
Concomitant
Respiratory Failure Hospitalization 52 Male 4/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/13/2005 56 Male 220 lb 4/24/2006 Germany
Primary
Concomitant
Hyponatraemia Hospitalization 2/15/2006 58 Female 214 lb 4/18/2006 Pharmacist United Kingdom
Primary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 4/27/2006 Physician France
Primary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 4/26/2006 Physician France
Primary
Concomitant
Weight Decreased Hospitalization 1/16/2006 81 Female 5/1/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 11/22/2005 71 Male 194 lb 5/9/2006 Physician Belgium
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/14/2006 64 Male Pharmacist United States
Primary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 5/15/2006 Physician France
Primary
Concomitant
Vomiting Required Intervention 1/2/2006 51 Male 161 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Injection Site Bruising 1/1/2006 67 Female 249 lb 4/17/2006 Consumer United States
Primary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 6/20/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/21/1999 62 Female 128 lb 7/10/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 4/28/2006 59 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 7/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 9/16/2005 59 Female 105 lb 6/30/2006 Physician Japan
Primary
Concomitant
Skin Exfoliation Hospitalization 6/19/2006 62 Male 7/7/2006 Pharmacist United States
Primary
Concomitant
Hypokalaemia Hospitalization 4/24/2006 55 Male Pharmacist United States
Primary
Concomitant
Renal Disorder 1/1/2004 80 Male 7/21/2006 Consumer United States
Primary
Concomitant
Throat Tightness Hospitalization 10/13/2005 49 Female 157 lb 7/21/2006 Physician United States
Primary
Secondary
Concomitant
Gastric Ulcer 6/21/2006 68 Male 238 lb 6/21/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 6/24/2006 71 Female 146 lb 7/20/2006 Netherlands
Primary
Concomitant
Gastrointestinal Toxicity Hospitalization 4/1/2006 74 Female 159 lb 8/8/2006 Consumer Mexico
Primary
Concomitant
Vomiting Required Intervention 7/30/2006 76 Female 118 lb 8/6/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 6/16/2006 77 Female 8/10/2006 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 8/17/2005 72 Male 8/8/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 6/14/2006 84 Female 8/23/2006 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 2/16/2006 80 Female 8/30/2006 Physician Japan
Primary
Secondary
Concomitant
Sedation 2/1/2006 83 Male 9/6/2006 Consumer United States
Primary
Concomitant
Vasculitis Other Serious 8/28/2006 38 Male 225 lb 9/7/2006 Consumer United States
Primary
Concomitant
Throat Tightness Hospitalization 9/15/2005 49 Female 9/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Stomatitis 4/1/2006 49 Male 173 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Renal Impairment Hospitalization 6/14/2006 84 Female 243 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 6/14/2006 84 Female 243 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Toxicity Hospitalization 4/1/2006 74 Female 159 lb 9/12/2006 Consumer Mexico
Primary
Concomitant
Renal Impairment Other Serious 6/14/2006 84 Female 9/7/2006 Denmark
Primary
Concomitant
Muscle Twitching Other Serious 1/1/2006 78 Female 9/7/2006 Denmark
Primary
Concomitant
Pneumonia Hospitalization 8/19/2006 28 Female 137 lb 9/15/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 9/22/2006 Other Health Professional France
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 8/19/2006 28 Female 137 lb 9/22/2006 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 6/5/2005 75 Female 174 lb 9/14/2006 Physician Poland
Primary
Secondary
Concomitant
International Normalised Ratio Abnormal Life Threatening 6/4/2006 89 Male 155 lb 6/5/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 6/5/2005 75 Female 174 lb 9/14/2006 Physician Poland
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/19/2006 28 Female 115 lb 9/25/2006 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/11/2006 79 Female 154 lb 10/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Circulatory Collapse Death 69 Male 9/30/2006 Physician Singapore
Primary
Secondary
Tachycardia Hospitalization 2/8/2005 43 Female 146 lb 9/27/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 9/27/2006 62 Male 230 lb 9/29/2006 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 79 Female 154 lb 9/29/2006 United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 10/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/1/2006 62 Male 176 lb 10/6/2006 Other Health Professional France
Primary
Concomitant
Vision Blurred Life Threatening 6/19/2006 86 Female 200 lb 9/15/2006 Consumer United States
Primary
Concomitant
Vaginal Candidiasis Hospitalization 3/25/2006 64 Female 10/9/2006 Consumer Australia
Primary
Concomitant
Hyperkalaemia Hospitalization 9/23/2006 58 Male Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 88 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Myalgia Required Intervention 7/27/2006 47 Male 265 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Hospitalization 4/1/2006 70 Male 10/5/2006 Japan
Primary
Concomitant
Myocardial Infarction Hospitalization 9/14/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Heart Rate Increased Other Serious 8/28/2006 1 Male 15 lb 10/20/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Linear Iga Disease Other Serious 73 Male 10/26/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/5/2006 91 Female 11/3/2006 Sweden
Primary
Secondary
Concomitant
Ulcer Hospitalization 9/1/2006 Male 150 lb 11/10/2006 Consumer Brazil
Primary
Concomitant
Ulcer Hospitalization 9/1/2006 Male 150 lb 11/10/2006 Consumer Brazil
Primary
Concomitant
Myocardial Ischaemia Death 69 Male 11/14/2006 Physician Singapore
Primary
Concomitant
Pulmonary Oedema Hospitalization 8/1/2006 81 Female 11/8/2006 United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 8/1/2006 81 Female 11/13/2006 United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 8/1/2006 81 Female 11/13/2006 United Kingdom
Primary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 11/17/2006 Lawyer United Kingdom
Primary
Secondary
Concomitant
Speech Disorder Other Serious 7/21/2006 86 Male 164 lb 7/26/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 8/2/2006 65 Male 185 lb 9/18/2006 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 9/15/2006 70 Male 12/1/2006 Other Health Professional France
Primary
Concomitant
Interacting
Diverticulitis Other Serious 11/12/2006 80 Male 12/4/2006 Other Health Professional Japan
Primary
Concomitant
Urethral Haemorrhage Other Serious 10/30/2006 Male 181 lb 12/4/2006 Physician Czech Republic
Primary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 11/28/2006 United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 9/15/2006 70 Male 12/14/2006 Physician Denmark
Primary
Concomitant
Interacting
Somnolence Other Serious 1/1/2006 61 Female 120 lb 1/2/2007 Other Health Professional United States
Primary
Concomitant
Visual Disturbance 6/19/2006 86 Female 200 lb 10/11/2006 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/17/2006 93 Female 1/2/2007 Italy
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Cardiac Failure Death 10/18/2005 65 Male 121 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/30/2005 60 Male 134 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 9/28/2006 68 Female 115 lb 1/4/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Peripheral Ischaemia Hospitalization 93 Female 1/9/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 2/17/2006 72 Male 183 lb 1/15/2007 Physician France
Primary
Concomitant
Haemorrhage Intracranial Other Serious 6/2/2006 Male 1/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/14/2006 80 Male 240 lb 1/18/2007 Pharmacist United States
Primary
Concomitant
Blood Urea Increased Life Threatening 12/19/2006 52 Male 1/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Gynaecomastia Other Serious 9/26/2006 64 Male 242 lb 9/26/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 10/18/2006 54 Female 100 lb 1/24/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/10/2007 59 Male 1/30/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 11/17/2006 82 Female 2/2/2007 Spain
Primary
Secondary
Concomitant
Productive Cough Hospitalization 11/20/2006 Male 230 lb 12/22/2006 Pharmacist United States
Primary
Concomitant
Gynaecomastia Hospitalization 9/3/2006 87 Male 185 lb 2/13/2007 Other Health Professional Spain
Primary
Concomitant
Psychotic Disorder Other Serious 9/1/2006 77 Male 121 lb 2/14/2007 Physician Sweden
Primary
Concomitant
Right Ventricular Failure Life Threatening 1/19/2006 33 Female 108 lb 2/9/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 11/17/2006 82 Female 2/14/2007 Spain
Primary
Secondary
Concomitant
Syncope Other Serious 2/9/2007 57 Female 2/26/2007 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/19/2006 28 Female 115 lb 3/5/2007 Consumer United States
Primary
Concomitant
Angina Pectoris Other Serious 2/1/2007 73 Female 3/13/2007 Consumer United States
Primary
Concomitant
Pericardial Effusion Other Serious Female 3/20/2007 Consumer Germany
Primary
Concomitant
Shunt Occlusion Other Serious Female 132 lb 3/23/2007 Physician Australia
Primary
Concomitant

Drug Data