Omeprazole combined with Sorafenib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Tachycardia Hospitalization 6/22/2005 76 Female 1/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/30/2006 49 Male 148 lb 2/9/2006 France
Primary
Concomitant
Weight Decreased Hospitalization 1/30/2006 49 Male 148 lb 2/22/2006 France
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 4/4/2006 26 Male 165 lb 4/7/2006 United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 4/3/2006 Male 148 lb 4/11/2006 Germany
Primary
Concomitant
Small Intestinal Haemorrhage Other Serious 4/4/2006 26 Male 165 lb 5/8/2006 United Kingdom
Primary
Secondary
Concomitant
Hallucination Other Serious 74 Female 141 lb 6/1/2006 Sweden
Primary
Concomitant
Mechanical Ileus Hospitalization 5/15/2006 52 Male 6/12/2006 Other Health Professional Italy
Primary
Concomitant
Skin Lesion Required Intervention 6/15/2006 55 Male 188 lb 6/15/2006 Pharmacist United States
Primary
Concomitant
Post Procedural Complication Hospitalization 5/15/2006 52 Male 6/16/2006 Italy
Primary
Concomitant
Post Procedural Complication Hospitalization 5/15/2006 52 Male 6/14/2006 Italy
Primary
Concomitant
Peritoneal Necrosis Hospitalization 5/15/2006 52 Male 6/27/2006 Italy
Primary
Concomitant
Tachycardia Hospitalization 4/10/2006 66 Female 7/17/2006 Other Health Professional France
Primary
Concomitant
Peritoneal Necrosis Hospitalization 5/15/2006 53 Male 9/21/2006 Physician Italy
Primary
Concomitant
Weight Decreased Life Threatening 5/4/2006 52 Male 130 lb 9/26/2006 Physician Poland
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/24/2006 75 Male 163 lb 9/26/2006 Physician France
Primary
Concomitant
Small Intestinal Haemorrhage Other Serious 4/4/2006 31 Male 165 lb 9/29/2006 United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 4/10/2006 66 Female 10/3/2006 Physician France
Primary
Concomitant
Oral Intake Reduced Other Serious 11/9/2005 69 Male 176 lb 10/9/2006 Physician United States
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 4/26/2006 59 Male 10/9/2006 Physician Germany
Primary
Concomitant
Cardiac Failure Life Threatening 9/9/2006 76 Male 161 lb 10/26/2006 Physician Italy
Primary
Concomitant
Tooth Malformation Hospitalization 10/23/2006 Male 194 lb 11/3/2006 Physician United Kingdom
Primary
Concomitant
Tooth Malformation Hospitalization 10/23/2006 Male 194 lb 11/8/2006 Physician United Kingdom
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/24/2006 75 Male 163 lb 11/10/2006 Physician France
Primary
Concomitant
Weight Decreased Life Threatening 5/4/2006 52 Male 130 lb 11/13/2006 Physician Poland
Primary
Concomitant
Fatigue Hospitalization 1/30/2006 50 Male 148 lb 12/4/2006 Physician France
Primary
Concomitant
Renal Failure Acute Hospitalization 3/24/2006 75 Male 163 lb 12/13/2006 Physician France
Primary
Concomitant
Respiratory Failure Death 11/3/2006 59 Male 12/18/2006 Physician Spain
Primary
Concomitant
Respiratory Failure Death 11/3/2006 59 Male 12/28/2006 Physician Spain
Primary
Concomitant
Hypomagnesaemia Hospitalization 12/18/2006 67 Male 181 lb 12/28/2006 Physician Germany
Primary
Concomitant
Hypocalcaemia Other Serious 11/9/2005 69 Male 176 lb 1/12/2007 Physician United States
Primary
Concomitant
Hyperthyroidism Hospitalization 2/17/2006 72 Male 183 lb 1/15/2007 Physician France
Primary
Concomitant
Coronary Artery Insufficiency Hospitalization 10/16/2006 73 Male 203 lb 1/16/2007 Physician France
Primary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 61 Male 1/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 3/24/2006 75 Male 163 lb 1/23/2007 Physician France
Primary
Concomitant
Periodontal Disease Hospitalization 1/30/2007 Male 159 lb 2/7/2007 Physician United Kingdom
Primary
Concomitant
Tremor Other Serious 11/28/2006 63 Male 128 lb 2/7/2007 Physician United States
Primary
Concomitant
Periodontal Disease Hospitalization 1/30/2007 Male 159 lb 2/12/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 61 Male 172 lb 2/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 61 Male 172 lb 2/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sarcoma Other Serious 12/1/2006 55 Male 128 lb 3/8/2007 Physician Italy
Primary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 61 Male 172 lb 3/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Periodontal Disease Hospitalization 1/30/2007 Male 159 lb 3/15/2007 Physician United Kingdom
Primary
Concomitant
Toothache Other Serious 12/1/2005 43 Female 243 lb 3/24/2007 France
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 3/13/2007 71 Male 148 lb 3/30/2007 Physician Spain
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 3/13/2007 71 Male 148 lb 4/3/2007 Physician Spain
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/7/2007 68 Male 112 lb 4/3/2007 Physician Brazil
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 3/7/2007 68 Male 112 lb 4/11/2007 Physician Brazil
Primary
Secondary
Concomitant
Tumour Embolism Hospitalization 3/13/2007 71 Male 148 lb 4/17/2007 Physician Spain
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 3/7/2007 68 Male 112 lb 4/25/2007 Physician Brazil
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 3/7/2007 68 Male 112 lb 5/2/2007 Physician Brazil
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/30/2007 74 Male 5/3/2007 Physician Italy
Primary
Concomitant
Sepsis Hospitalization 3/30/2007 74 Male 5/7/2007 Physician Italy
Primary
Concomitant
Sarcoma Other Serious 12/1/2006 55 Male 128 lb 6/11/2007 Physician Italy
Primary
Concomitant
Hypomagnesaemia Hospitalization 12/18/2006 67 Male 181 lb 7/27/2007 Physician Germany
Primary
Concomitant
Urinary Retention Other Serious 5/2/2007 48 Male 183 lb 8/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 4/3/2006 49 Male 148 lb 8/10/2007 Physician Germany
Primary
Concomitant
Periodontal Disease Hospitalization 1/30/2007 67 Male 159 lb 8/24/2007 Physician United Kingdom
Primary
Concomitant
Tooth Disorder Hospitalization 10/23/2006 66 Male 194 lb 8/24/2007 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 8/21/2007 65 Male 9/13/2007 Physician Netherlands
Primary
Secondary
Concomitant
Cerebral Ischaemia Other Serious 8/7/2007 40 Male 159 lb 9/21/2007 Physician Spain
Primary
Secondary
Concomitant
Cerebral Ischaemia Other Serious 8/7/2007 40 Male 159 lb 9/24/2007 Physician Spain
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 4/10/2006 66 Female 10/1/2007 Physician France
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/26/2006 59 Male 10/8/2007 Physician Germany
Primary
Concomitant
Scrotal Ulcer Hospitalization 9/25/2007 75 Male 10/15/2007 Physician Italy
Primary
Concomitant
Sudden Death Hospitalization 10/22/2007 58 Male 11/9/2007 Physician Spain
Primary
Concomitant
Urinary Retention Other Serious 5/2/2007 57 Male 183 lb 11/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Scrotal Ulcer Hospitalization 9/25/2007 75 Male 11/19/2007 Physician Italy
Primary
Concomitant
Sudden Death Hospitalization 10/22/2007 58 Male 11/26/2007 Physician Spain
Primary
Concomitant
Urinary Retention Other Serious 5/2/2007 57 Male 183 lb 11/30/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 3/6/2007 49 Male 146 lb 12/6/2007 Physician Spain
Primary
Concomitant
Sigmoiditis Hospitalization 11/28/2007 85 Female 1/15/2008 Physician Spain
Primary
Concomitant
Sigmoiditis Hospitalization 11/28/2007 85 Female 1/17/2008 Physician Spain
Primary
Concomitant
Sudden Death Hospitalization 10/22/2007 58 Male 1/22/2008 Physician Spain
Primary
Concomitant
Urinary Retention Other Serious 5/2/2007 57 Male 183 lb 2/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Other Serious 4/4/2006 31 Male 165 lb 2/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Scrotal Ulcer Hospitalization 9/25/2007 75 Male 2/12/2008 Physician Italy
Primary
Concomitant
Hallucination Other Serious 5/24/2006 75 Female 141 lb 2/14/2008 Physician Sweden
Primary
Concomitant
Vomiting Hospitalization 5/6/2007 81 Female 121 lb 3/4/2008 Physician Brazil
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 7/4/2006 75 Female 3/5/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Retention Other Serious 5/2/2007 57 Male 183 lb 3/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 4/19/2008 57 Female 147 lb 5/14/2008 Physician United States
Primary
Secondary
Concomitant
Sigmoiditis Hospitalization 11/28/2007 85 Female 5/20/2008 Physician Spain
Primary
Concomitant
Thrombocytopenia Hospitalization 4/19/2008 57 Female 147 lb 6/3/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/19/2008 57 Female 147 lb 6/6/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/15/2008 58 Female 6/6/2008 Physician United States
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 4/29/2008 46 Male 159 lb 7/8/2008 Physician Italy
Primary
Concomitant
Haemoglobin Decreased Other Serious 5/1/2008 82 Male 176 lb 7/10/2008 Physician Italy
Primary
Concomitant
Vomiting Hospitalization 5/26/2008 68 Male 148 lb 7/10/2008 Physician Spain
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/5/2008 70 Male 181 lb 7/16/2008 Mexico
Primary
Secondary
Concomitant
Intestinal Haemorrhage Other Serious 4/4/2006 31 Male 165 lb 7/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Waist Circumference Increased Hospitalization 2/12/2008 41 Male 249 lb 7/17/2008 Physician Mexico
Primary
Concomitant
Pyrexia Hospitalization 9/10/2007 60 Male 181 lb 7/31/2008 Physician Denmark
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/20/2007 70 Male 181 lb 7/31/2008 Mexico
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/31/2008 Male 215 lb 8/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Life Threatening 7/17/2008 68 Male 157 lb 8/8/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2007 70 Male 137 lb 8/15/2008 Physician Canada
Primary
Concomitant
Gingivitis Hospitalization 1/30/2007 67 Male 159 lb 8/18/2008 Physician Germany
Primary
Concomitant
Tooth Extraction Hospitalization 10/23/2006 66 Male 194 lb 8/18/2008 Physician Germany
Primary
Concomitant
Prostate Cancer Hospitalization 8/13/2008 Male 152 lb 8/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Prostate Cancer Hospitalization 8/13/2008 Male 152 lb 8/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Life Threatening 7/17/2008 68 Male 157 lb 9/5/2008 United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/18/2007 70 Male 181 lb 9/18/2008 Mexico
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/24/2007 67 Male 159 lb 9/18/2008 Physician Italy
Primary
Secondary
Concomitant
Dehydration Hospitalization 9/30/2008 Male 240 lb 10/1/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 7/31/2008 Male 215 lb 10/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 10/18/2007 84 Female 10/30/2008 Physician Spain
Primary
Concomitant
Diarrhoea Hospitalization 9/30/2008 Male 240 lb 10/1/2008 Other Health Professional United States
Primary
Concomitant
Skin Toxicity Hospitalization 6/26/2008 71 Female 126 lb 11/14/2008 Physician Spain
Primary
Secondary
Concomitant
Hypotension Other Serious 11/4/2008 40 Male 130 lb 11/17/2008 Physician Italy
Primary
Concomitant
Atrial Fibrillation Hospitalization 10/24/2008 62 Male 234 lb 11/21/2008 Physician United States
Primary
Secondary
Concomitant
Sudden Death Hospitalization 10/22/2007 58 Male 12/1/2008 Physician Spain
Primary
Concomitant
Waist Circumference Increased Hospitalization 2/12/2008 41 Male 249 lb 12/1/2008 Physician Mexico
Primary
Concomitant
Sudden Death Hospitalization 10/22/2007 58 Male 12/2/2008 Physician Spain
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/21/2008 53 Male 141 lb 12/4/2008 Physician Italy
Primary
Concomitant
Waist Circumference Increased Hospitalization 2/12/2008 41 Male 249 lb 12/11/2008 Physician Mexico
Primary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 61 Male 172 lb 12/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Aortic Dissection Life Threatening 9/14/2008 50 Male 181 lb 1/12/2009 Physician Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/2/2008 69 Female 132 lb 1/19/2009 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 10/2/2008 69 Female 132 lb 2/5/2009 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/15/2008 58 Female 2/4/2009 Physician United States
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 1/11/2009 60 Female 220 lb 2/11/2009 Physician France
Primary
Concomitant
Haematemesis Hospitalization 1/29/2009 59 Male 134 lb 2/11/2009 Physician Singapore
Primary
Secondary
Concomitant
Electrocardiogram Abnormal Other Serious 1/30/2009 37 Male 172 lb 2/11/2009 Physician Italy
Primary
Concomitant
Vomiting Hospitalization 4/19/2008 57 Female 147 lb 2/6/2009 Physician United States
Primary
Secondary
Concomitant
Tumour Haemorrhage Other Serious 1/11/2009 60 Female 220 lb 2/18/2009 Physician France
Primary
Concomitant
Vessel Puncture Site Haematoma Hospitalization 4/19/2008 57 Female 147 lb 2/19/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/21/2008 53 Male 141 lb 2/25/2009 Physician Italy
Primary
Concomitant
Generalised Oedema Hospitalization 3/10/2009 62 Female 66 lb 3/18/2009 United Kingdom
Primary
Concomitant
Generalised Oedema Hospitalization 3/10/2009 62 Female 66 lb 3/25/2009 United Kingdom
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 10/22/2007 58 Male 3/25/2009 Physician Spain
Primary
Concomitant
Aortic Dissection Hospitalization 9/14/2008 50 Male 181 lb 4/16/2009 Physician Italy
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 3/10/2009 62 Female 66 lb 4/21/2009 United Kingdom
Primary
Concomitant
Right Ventricular Failure Hospitalization 3/10/2009 62 Female 66 lb 4/21/2009 United Kingdom
Primary
Concomitant
Right Ventricular Failure Hospitalization 3/10/2009 62 Female 66 lb 4/24/2009 United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/26/2009 58 Male 157 lb 5/8/2009 Physician Spain
Primary
Secondary
Concomitant
Aortic Dissection Life Threatening 9/14/2008 50 Male 181 lb 5/11/2009 Physician Italy
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 5/19/2009 65 Male 123 lb 5/26/2009 Physician Belgium
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 5/16/2009 70 Male 152 lb 5/27/2009 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 5/30/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/29/2008 60 Female 146 lb 6/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/2/2008 69 Female 132 lb 6/10/2009 United Kingdom
Primary
Concomitant
Oedema Other Serious 4/27/2009 54 Male 115 lb 6/16/2009 Physician United States
Primary
Secondary
Concomitant
Herpes Zoster Ophthalmic Other Serious 5/19/2009 76 Male 165 lb 6/17/2009 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 6/11/2009 Male 135 lb 6/18/2009 Physician Singapore
Primary
Concomitant
Pyrexia Hospitalization 6/10/2009 50 Male 134 lb 6/22/2009 Physician United States
Primary
Concomitant
Salmonellosis Hospitalization 6/11/2009 Male 135 lb 7/9/2009 Physician Singapore
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 7/10/2009 Physician United States
Primary
Concomitant
Pancytopenia Other Serious 5/19/2009 65 Male 123 lb 7/16/2009 Physician Belgium
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/19/2009 65 Male 123 lb 7/21/2009 Physician Belgium
Primary
Secondary
Concomitant

Drug Data