Olanzapine combined with Valproate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 2/5/2000 27 Male 12/23/2005 Australia
Primary
Concomitant
Thinking Abnormal Hospitalization 12/1/2004 38 Female 280 lb 1/19/2006 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/17/2005 44 Male 2/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sedation Hospitalization 1/1/2005 Male 2/11/2006 Other Health Professional Australia
Primary
Concomitant
Shock Life Threatening 19 Male 143 lb 2/21/2006 Physician France
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/18/2005 36 Female 126 lb 12/14/2005 Physician United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 8/23/2005 50 Male 201 lb 12/14/2005 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Death 4/1/1998 Male 3/31/2006 Physician Australia
Primary
Concomitant
Drug Toxicity Death 11/19/2004 31 Male 375 lb 3/15/2005 Physician United States
Primary
Secondary
Concomitant
Restless Legs Syndrome Hospitalization 59 Female 4/6/2006 Switzerland
Primary
Secondary
Pancreatitis Other Serious 32 Male 4/19/2006 Physician Spain
Primary
Concomitant
Pancreatitis Other Serious 14 Female 4/19/2006 Physician Spain
Primary
Concomitant
Restless Legs Syndrome Hospitalization 59 Female 4/26/2006 Switzerland
Primary
Secondary
Scoliosis Hospitalization 59 Female 4/26/2006 Switzerland
Primary
Secondary
Neutrophil Count Decreased 10/1/2004 27 Female 5/15/2006 United Kingdom
Primary
Concomitant
Sinus Tachycardia Other Serious 3/3/2006 30 Female 6/4/2006 Physician Ireland
Primary
Concomitant
Therapy Non-responder Other Serious 17 Female 6/27/2006 Physician Spain
Primary
Secondary
Concomitant
Hypomania Other Serious 1/1/2002 30 Male 6/29/2006 Canada
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 2/2/2006 49 Male 3/21/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/31/2006 59 Male 4/3/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 9/19/2005 44 Female 1/19/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/3/2005 42 Male 1/25/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/14/2005 47 Male 6/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/16/2005 37 Male 210 lb 2/14/2006 United States
Primary
Concomitant
Red Blood Cell Count Decreased Required Intervention 7/6/2006 35 Female 172 lb 7/25/2006 United States
Primary
Concomitant
Impulsive Behaviour Required Intervention 1/1/2006 39 Male 8/4/2006 Pharmacist United Kingdom
Primary
Concomitant
Psychiatric Symptom Hospitalization 8/3/2006 41 Female 8/22/2006 Physician Japan
Primary
Concomitant
Granulocytopenia 1/3/2006 60 Male 5/9/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/30/2006 43 Male 118 lb 5/15/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/5/2000 27 Male 8/14/2006 Other Health Professional Australia
Primary
Concomitant
Treatment Noncompliance Death 8/1/2006 58 Male 8/19/2006 Physician Australia
Primary
Concomitant
Hallucination Hospitalization 8/3/2006 42 Female 8/31/2006 Physician Japan
Primary
Concomitant
Renal Failure Chronic Death 21 Male 9/25/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 21 Male 9/25/2006 United States
Primary
Concomitant
Treatment Noncompliance Death 8/1/2006 58 Male 9/28/2006 Other Health Professional Australia
Primary
Concomitant
Renal Failure Chronic Other Serious 2/15/2006 21 Male 10/12/2006 Consumer France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 36 Male 10/13/2006 France
Primary
Concomitant
Interacting
Metastasis Death 66 Female 170 lb 10/3/2006 Other Health Professional Australia
Primary
Concomitant
Pancreatitis Other Serious Male 10/18/2006 Consumer France
Primary
Secondary
Concomitant
Mania Hospitalization 2/17/2006 56 Female 10/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Mania Hospitalization 2/17/2006 56 Female 10/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 9/21/2006 57 Male 112 lb 10/12/2006 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 36 Male 11/3/2006 France
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 36 Male 11/13/2006 France
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 36 Male 11/13/2006 France
Primary
Concomitant
Interacting
Subdural Haematoma Other Serious 9/21/2006 57 Male 112 lb 11/6/2006 Japan
Primary
Concomitant
Hyponatraemia Other Serious 1/7/2005 Female 165 lb 12/8/2006 Physician Germany
Primary
Secondary
Concomitant
Interacting
Hyponatraemia Other Serious 1/7/2005 Female 165 lb 12/8/2006 Physician Germany
Primary
Secondary
Concomitant
Interacting
Hyponatraemia Other Serious 1/7/2005 Female 165 lb 12/22/2006 Physician Germany
Primary
Secondary
Concomitant
Interacting
Tachycardia Other Serious Female 1/4/2007 Consumer Ireland
Primary
Secondary
Pancreatitis Other Serious 12/26/2005 Male 2/1/2007 Consumer France
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 26 Male 2/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Restlessness Other Serious 11/1/2001 Female 2/6/2007 Physician United Kingdom
Primary
Concomitant
Type Iv Hypersensitivity Reaction Other Serious 18 Female 2/9/2007 Consumer United States
Primary
Concomitant
Balance Disorder Hospitalization 1/1/2006 60 Female 2/23/2007 Physician Australia
Primary
Concomitant
Pancreatitis Other Serious 12/26/2005 Male 3/30/2007 Consumer France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2000 43 Male 4/28/2007 Other Health Professional United States
Primary
Concomitant
Mania Hospitalization 12/11/2006 Male 119 lb 5/1/2007 Physician Malaysia
Primary
Secondary
Concomitant
Somnolence Hospitalization 9/4/2006 22 Female 5/2/2007 Physician Japan
Primary
Concomitant
Serotonin Syndrome Other Serious 41 Male 5/4/2007 Switzerland
Primary
Secondary
Concomitant
Bipolar Disorder Hospitalization 21 Female 128 lb 5/7/2007 Physician Romania
Primary
Concomitant
Bipolar Disorder Hospitalization 6/26/2006 50 Male 5/7/2007 Physician Romania
Primary
Concomitant
Wheezing Life Threatening 9/4/2006 22 Female 5/11/2007 Physician Japan
Primary
Secondary
Overdose Other Serious Male 5/18/2007 Pharmacist France
Primary
Secondary
Pyrexia Other Serious 1/26/2007 17 Male 5/18/2007 United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 12/28/2005 41 Male 182 lb 4/2/2007 Physician United States
Primary
Secondary
Concomitant
Bipolar Disorder Hospitalization 10/13/2006 21 Female 128 lb 6/4/2007 Physician Romania
Primary
Concomitant
Pyrexia Other Serious 5/6/2007 17 Male 6/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tardive Dyskinesia Disability 8/1/2006 58 Male 6/22/2007 United Kingdom
Primary
Concomitant
Tongue Paralysis Disability 8/1/2006 58 Male 6/29/2007 United Kingdom
Primary
Concomitant
Haemolytic Anaemia Other Serious 16 Female 7/11/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Death 2/3/2006 24 Female 7/27/2007 Physician Japan
Primary
Concomitant
Suicide Attempt Other Serious 41 Female 7/27/2007 Other Health Professional France
Primary
Secondary
Vomiting Death 2/3/2006 24 Female 7/30/2007 Physician Japan
Primary
Concomitant
Mania Hospitalization 12/11/2006 Male 119 lb 8/6/2007 Physician Malaysia
Primary
Concomitant
Vomiting Death 2/3/2006 24 Female 8/8/2007 Physician Japan
Primary
Concomitant
Bipolar Disorder Hospitalization 6/2/2007 50 Male 8/7/2007 Physician Romania
Primary
Concomitant
Haemolytic Anaemia Other Serious 16 Female 8/10/2007 Physician United Kingdom
Primary
Concomitant
Syncope Hospitalization 6/29/2007 43 Male 8/28/2007 France
Primary
Secondary
Concomitant
Granulocytopenia Death Male 9/20/2007 Consumer Japan
Primary
Concomitant
Drug Toxicity Other Serious 76 Female 10/19/2007 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/22/2007 16 Female 234 lb 11/27/2007 Pharmacist United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 54 Male 11/28/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 44 Female 12/28/2007 Physician United Kingdom
Primary
Concomitant
Restless Legs Syndrome Hospitalization 10/22/2007 36 Male 1/4/2008 Physician Korea, Republic Of
Primary
Concomitant
Mood Altered Other Serious 12/13/2007 38 Female 1/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Restlessness Hospitalization 12/28/2007 21 Male 1/23/2008 Other Health Professional Japan
Primary
Concomitant
Restless Legs Syndrome Hospitalization 10/22/2007 36 Male 1/25/2008 Physician Korea, Republic Of
Primary
Concomitant
Pulmonary Embolism Hospitalization 24 Female 2/3/2008 Physician Germany
Primary
Concomitant
Neutrophil Count Decreased Other Serious 12/9/2007 28 Male 2/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Weight Increased Other Serious 44 Female 2/29/2008 France
Primary
Secondary
Withdrawal Syndrome Other Serious 45 Male 2/29/2008 United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 12/9/2007 28 Male 3/6/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Suicidal Ideation Other Serious 1/1/2008 Male 3/14/2008 Physician United Kingdom
Primary
Concomitant
Interacting
Neutrophil Count Decreased Other Serious 12/9/2007 28 Male 3/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Restless Legs Syndrome Hospitalization 1/1/2007 36 Male 3/12/2008 Physician Korea, Republic Of
Primary
Concomitant
Hepatotoxicity Other Serious 38 Male 3/28/2008 Turkey
Primary
Concomitant
Pulmonary Embolism Hospitalization 24 Female 3/27/2008 Physician Germany
Primary
Secondary
Concomitant
Prolonged Labour Other Serious Female 4/11/2008 Physician Ireland
Primary
Concomitant
Urinary Incontinence Disability 1/1/2008 49 Male 4/11/2008 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/3/2007 72 Female 4/21/2008 Other Health Professional Australia
Primary
Concomitant
Vomiting Hospitalization 7/3/2007 72 Female 4/23/2008 Other Health Professional Australia
Primary
Concomitant
Weight Increased Other Serious 44 Female 4/24/2008 Physician United Kingdom
Primary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Antipsychotic Drug Level Increased Hospitalization 36 Female 5/28/2008 Consumer Australia
Primary
Concomitant
Interacting
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 44 Female 6/5/2008 France
Primary
Secondary
Weight Increased Other Serious 44 Female 6/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Weight Increased Other Serious 44 Female 6/6/2008 Physician United Kingdom
Primary
Concomitant
Unevaluable Event Hospitalization 3/12/2008 21 Male 6/13/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 44 Female 6/18/2008 Physician United Kingdom
Primary
Concomitant
Unevaluable Event Other Serious 3/12/2008 21 Male 6/19/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/1/2006 22 Male 6/19/2008 Physician France
Primary
Secondary
Pyrexia Other Serious 4/24/2006 Male 6/24/2008 Physician Australia
Primary
Concomitant
Weight Increased Other Serious 44 Female 6/26/2008 Physician United Kingdom
Primary
Concomitant
Unevaluable Event Other Serious 3/12/2008 21 Male 6/30/2008 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 45 Male 6/27/2008 United States
Primary
Concomitant
Hypoaesthesia Other Serious 4/1/2008 Female 7/18/2008 Physician United States
Primary
Concomitant
Hypoaesthesia Other Serious 4/1/2008 Female 8/1/2008 Physician United States
Primary
Concomitant
Suicide Attempt Other Serious 52 Male 8/4/2008 France
Primary
Concomitant
Hypoaesthesia Other Serious 4/6/2008 Female 97 lb 8/8/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 8/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 9/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 44 Female 9/16/2008 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 8/1/2007 22 Male 9/24/2008 Consumer United States
Primary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 10/2/2008 France
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 10/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria Hospitalization 10/18/2007 Female 10/1/2008 Physician Australia
Primary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 10/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Psychiatric Symptom Hospitalization 43 Male 174 lb 10/17/2008 Other Health Professional Japan
Primary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 10/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Psychiatric Symptom Hospitalization 43 Male 174 lb 10/31/2008 Other Health Professional Japan
Primary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 11/11/2008 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 11/19/2008 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 16 Female 11/20/2008 Physician United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 11/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 11/26/2008 Other Health Professional France
Primary
Secondary
Concomitant
Encephalopathy Other Serious 52 Male 12/11/2008 France
Primary
Concomitant
Varicose Vein Hospitalization 12/16/2008 Female 1/2/2009 Physician New Zealand
Primary
Concomitant
Mania Hospitalization 40 Male 1/12/2009
Primary
Concomitant
Drug Level Changed 3/4/2009 Consumer United States
Primary
Interacting
Oedema Peripheral Female 3/4/2009 Physician United States
Primary
Concomitant
Hepatotoxicity 3/4/2009 Physician United States
Primary
Interacting
Neutropenia Other Serious 2/2/2009 15 Female 161 lb 2/25/2009 Physician United Kingdom
Primary
Concomitant
Hallucination Other Serious 5/1/2006 60 Male 3/11/2009 France
Primary
Interacting
Weight Decreased Other Serious 1/1/2003 Male 3/24/2009 Physician United Kingdom
Primary
Concomitant
Hallucination Other Serious 5/1/2006 60 Male 3/26/2009 France
Primary
Interacting
Panic Reaction Other Serious 5/1/2006 Male 3/27/2009 Consumer Germany
Primary
Concomitant
Weight Increased Other Serious 16 Female 4/2/2009 Physician United Kingdom
Primary
Concomitant

Drug Data