Olanzapine combined with Quetiapine Fumarate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neuroleptic Malignant Syndrome Hospitalization 4/1/2005 Female 1/3/2006 Physician Japan
Primary
Interacting
Tachycardia Other Serious 26 Male 1/16/2006 Consumer Canada
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/17/2005 56 Male 220 lb 1/16/2006 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 1/1/2004 24 1/13/2006 United States
Primary
Secondary
Respiratory Arrest Death 37 Male 2/7/2006 Pharmacist United States
Primary
Secondary
Treatment Noncompliance Hospitalization 52 Male 3/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tachypnoea Other Serious 36 Female 5/5/2006 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Required Intervention 9/1/2005 15 Male 1/31/2006 Physician United States
Primary
Secondary
Concomitant
Failure To Thrive Death 5/15/2006 58 Male 5/31/2006 United States
Primary
Concomitant
Metabolic Acidosis Hospitalization 5/25/2006 Female 6/1/2006 Other Health Professional United States
Primary
Concomitant
Platelet Count Increased 28 Male 6/7/2006 Pharmacist Japan
Primary
Concomitant
Therapy Non-responder Other Serious 17 Female 6/27/2006 Physician Spain
Primary
Secondary
Concomitant
Heat Stroke Death 7/9/2006 53 Male 223 lb 7/20/2006 Physician Japan
Primary
Concomitant
Stupor Hospitalization 74 Male 7/24/2006 Physician United States
Primary
Secondary
Concomitant
Heat Stroke Death 7/9/2006 53 Male 223 lb 8/9/2006 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 69 Male 8/7/2006 Physician United States
Primary
Secondary
Neuroleptic Malignant Syndrome Other Serious 66 Female 8/3/2006 Pharmacist United States
Primary
Concomitant
Psychiatric Symptom Hospitalization 8/3/2006 41 Female 8/22/2006 Physician Japan
Primary
Concomitant
Hallucination Hospitalization 8/3/2006 42 Female 8/31/2006 Physician Japan
Primary
Concomitant
Polydactyly Congenital Anomaly 8/31/2006 Physician Italy
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2000 50 Male 333 lb 11/8/2006 Lawyer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2000 50 Male 333 lb 11/13/2006 Lawyer United States
Primary
Concomitant
Completed Suicide Death 61 11/14/2006 Other Health Professional United States
Primary
Secondary
Wrong Technique In Drug Usage Process Other Serious 1/1/2000 50 Male 333 lb 11/16/2006 Physician United States
Primary
Concomitant
Completed Suicide Death 61 11/16/2006 Physician United States
Primary
Secondary
Electroencephalogram Abnormal Other Serious 5/1/2006 17 Female 12/6/2006 Physician United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2002 Female 12/21/2006 Consumer United States
Primary
Secondary
Concomitant
Interacting
Completed Suicide Death 1/1/2005 61 1/3/2007 United States
Primary
Secondary
Completed Suicide Death 1/1/2005 61 1/5/2007 United States
Primary
Secondary
Posture Abnormal Other Serious 52 Female 1/19/2007 Other Health Professional Spain
Primary
Secondary
Encephalopathy Hospitalization 50 Female 150 lb 1/4/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/1/2005 37 265 lb 10/10/2006 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/4/2005 Female 1/26/2007 Physician Canada
Primary
Concomitant
Type Iv Hypersensitivity Reaction Other Serious 18 Female 2/9/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 37 Male 265 lb 2/21/2007 Consumer United States
Primary
Concomitant
Neutropenia Other Serious 36 Female 3/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Neutropenia Other Serious 36 Female 3/7/2007 France
Primary
Secondary
Concomitant
Weight Increased Other Serious 33 Female 168 lb 3/14/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Vomiting Hospitalization 19 Male 154 lb 3/14/2007 Physician United States
Primary
Secondary
Concomitant
Extrapyramidal Disorder Required Intervention 82 Female 8/21/2004 United States
Primary
Secondary
Neuroleptic Malignant Syndrome Hospitalization 31 Male 8/25/2005 United States
Primary
Secondary
Electrocardiogram Qt Corrected Interval Prolonged Required Intervention 66 Female 8/21/2004 Physician United States
Primary
Secondary
Weight Increased Other Serious 33 Female 168 lb 4/6/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Liver Disorder 57 Male 95 lb 4/24/2007 Physician Japan
Primary
Concomitant
Liver Disorder 57 Male 95 lb 4/27/2007 Physician Japan
Primary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/3/2006 50 Female 150 lb 5/8/2007 Consumer United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 60 Female 5/1/2007 Germany
Primary
Secondary
White Blood Cell Count Increased Hospitalization 2/16/2002 40 Female 5/26/2007 Physician Canada
Primary
Secondary
Concomitant
Tardive Dyskinesia Disability 8/1/2006 58 Male 6/20/2007 United Kingdom
Primary
Concomitant
Tongue Paralysis Disability 8/1/2006 58 Male 6/20/2007 United Kingdom
Primary
Concomitant
Torticollis Other Serious 60 Female 8/24/2007 France
Primary
Concomitant
Interacting
Refusal Of Treatment By Patient Hospitalization 6/18/2007 62 Male 9/25/2007 Japan
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 30 Male 10/3/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 54 Female 10/3/2007
Primary
Secondary
Concomitant
Hypotension Other Serious 9/23/2007 Female 97 lb 10/4/2007 Physician Portugal
Primary
Concomitant
Epilepsy Other Serious 9/23/2007 Female 97 lb 10/10/2007 Physician Portugal
Primary
Concomitant
Weight Increased Other Serious 3/30/2007 24 Male 11/16/2007 Other Health Professional France
Primary
Secondary
Concomitant
Overdose Other Serious Female 195 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 9/17/2007 Female 11/30/2007 Physician Finland
Primary
Concomitant
Psychotic Disorder Hospitalization 9/3/2007 67 Male 12/28/2007 Japan
Primary
Concomitant
Vision Blurred Other Serious 37 Female 1/10/2008 Canada
Primary
Secondary
Concomitant
Hallucination, Auditory Hospitalization 9/3/2007 67 Male 2/6/2008 Japan
Primary
Concomitant
Wheezing Other Serious 11/15/2007 57 Male 2/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Shock Other Serious 2/5/2008 27 Male 138 lb 2/16/2008 Pharmacist Canada
Primary
Concomitant
Rash Other Serious 20 Male 2/22/2008 Consumer United States
Primary
Secondary
Hallucination, Auditory Disability 1/29/2008 59 Female 3/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 41 Male 2/2/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 74 Female 3/17/2008 Physician Netherlands
Primary
Concomitant
Splenomegaly Disability 10/17/2007 Male 203 lb 4/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pregnancy Other Serious 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Priapism Other Serious 23 Male 5/16/2008 United States
Primary
Secondary
Interacting
Parkinsonism Other Serious 58 Female 5/21/2008 Japan
Primary
Concomitant
Suicidal Ideation Other Serious 58 Female 6/2/2008 Other Health Professional Japan
Primary
Concomitant
Aortic Valve Stenosis Other Serious 22 Female 6/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Priapism Other Serious 23 Male 6/4/2008 United States
Primary
Secondary
Interacting
Traumatic Shock Other Serious 2/4/1999 Female 6/10/2008 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 3/12/2008 21 Male 6/13/2008 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 3/12/2008 21 Male 6/19/2008 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 4/13/2008 53 Male 6/27/2008 Other Health Professional France
Primary
Concomitant
Interacting
Unevaluable Event Other Serious 3/12/2008 21 Male 6/30/2008 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 1/1/2007 Male 174 lb 7/3/2008 United States
Primary
Secondary
Concomitant
Self-medication Hospitalization 4/4/2008 51 Female 7/11/2008 Australia
Primary
Concomitant
Hyponatraemia Other Serious 4/13/2008 53 Male 8/15/2008 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 55 Male 8/25/2008 Physician United States
Primary
Secondary
Concomitant
Pathological Gambling Other Serious 57 Male 9/2/2008 Physician Japan
Primary
Secondary
Concomitant
Aortic Valve Stenosis Other Serious 22 Female 9/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 13 Female 9/23/2008 Physician United States
Primary
Secondary
Somnolence Hospitalization 13 Female 10/10/2008 Other Health Professional Japan
Primary
Concomitant
Somnolence 2/1/2007 13 Female 88 lb 11/3/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Somnolence Hospitalization 2/1/2007 13 Female 88 lb 11/6/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 19 Female 11/19/2008 Physician El Salvador
Primary
Concomitant
Suprapubic Pain 66 Female 11/24/2008 United Kingdom
Primary
Concomitant
Completed Suicide Death 61 1/27/2009 Physician United States
Primary
Concomitant
Drug Toxicity Death Female 2/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 20 Male 2/26/2009
Primary
Secondary
Mania Other Serious 22 Male 2/27/2009 Consumer United States
Primary
Secondary
Psychotic Disorder 17 Male 3/12/2009 Consumer
Primary
Concomitant
Interacting
Pancreatitis 3/12/2009 Physician
Primary
Concomitant
Treatment Noncompliance 50 Female 3/12/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 24 Male 3/21/2009 Physician Spain
Primary
Secondary
Concomitant
Suspiciousness Other Serious 37 Male 3/26/2009 Physician Taiwan, Province Of China
Primary
Secondary
Drug Toxicity Death 32 Male 4/3/2009
Primary
Secondary
Mania Hospitalization 4/25/2006 Male 147 lb 4/17/2009 Physician United States
Primary
Concomitant
Propofol Infusion Syndrome Other Serious 36 Female 5/26/2009 Pharmacist United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 15 Female 6/1/2009 Physician Canada
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 15 Female 6/12/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/26/2009 48 Male 6/17/2009 Physician United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 4/1/2009 Male 6/19/2009 Other Health Professional Ireland
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 15 Female 6/15/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Sepsis Hospitalization 36 Female 7/13/2009 United States
Primary
Secondary
Drug Ineffective Death 7/8/2009 23 Male 8/11/2009 Physician China
Primary
Concomitant
No Therapeutic Response Hospitalization 79 Female 8/28/2009 Spain
Primary
Secondary
Thinking Abnormal Other Serious Female 7/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 26 Male 9/18/2009 Physician Korea, Republic Of
Primary
Secondary
No Therapeutic Response Hospitalization 79 Female 9/12/2009 Spain
Primary
Secondary
Refusal Of Treatment By Patient Other Serious 42 Female 9/15/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Required Intervention 6/28/2009 51 Male 226 lb 9/16/2009 Pharmacist United States
Primary
Secondary
Weight Increased Hospitalization 6/1/2009 48 Female 9/18/2009 Pharmacist United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 55 Female 10/15/2009 Physician Switzerland
Primary
Concomitant
Judgement Impaired Hospitalization 26 Male 192 lb 11/11/2009 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 55 Female 12/3/2009 Switzerland
Primary
Secondary
Disorientation Other Serious 11/2/2009 45 Female 12/17/2009 Physician United Kingdom
Primary
Concomitant
Metabolic Syndrome Hospitalization 28 Female 1/8/2010 France
Primary
Secondary
Respiratory Arrest Hospitalization 40 Female 1/11/2010 Other Health Professional United States
Primary
Secondary
Metabolic Syndrome Hospitalization 28 Female 1/26/2010 France
Primary
Secondary
Treatment Noncompliance Hospitalization 40 Female 2/1/2010 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/17/2009 67 Male 2/5/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Male 6/14/2010 Canada
Primary
Concomitant
Cerebral Infarction Hospitalization 10/8/2010 27 Male 10/15/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 10/8/2010 27 Male 10/29/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2010 53 Female 11/10/2010 Physician Denmark
Primary
Secondary
Concomitant
Pneumonia Death 9/14/2010 63 Male 3/3/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Drug Administration Error Death 3/18/2011 Other Health Professional Australia
Primary
Secondary
Bipolar Disorder Hospitalization 57 Female 3/28/2011 Other Health Professional Japan
Primary
Concomitant
Bipolar Disorder Hospitalization 3/28/2011 Other Health Professional Japan
Primary
Concomitant
Bipolar Disorder Hospitalization 57 Female 4/14/2011 Other Health Professional Japan
Primary
Concomitant
Confusional State Death 74 Male 5/11/2011 Other Health Professional Australia
Primary
Secondary
Bipolar Ii Disorder Hospitalization 63 Female 6/16/2011 Other Health Professional Japan
Primary
Concomitant
Deep Vein Thrombosis Death 69 Female 7/7/2011 Physician Poland
Primary
Secondary
Pyrexia Other Serious 9/14/2010 69 Male 143 lb 7/25/2011 Physician Japan
Primary
Concomitant
Cardiac Arrest Death 1/1/2008 40 Female 7/21/2011 Physician United States
Primary
Secondary
Cognitive Disorder Other Serious 84 Female 7/29/2011 Other Health Professional Japan
Primary
Secondary
Deep Vein Thrombosis Death 69 Female 8/4/2011 Poland
Primary
Secondary
Antiphospholipid Antibodies Positive Hospitalization 69 Female 9/19/2011 Other Health Professional Poland
Primary
Secondary
Condition Aggravated Other Serious 55 Female 10/7/2011 Other Health Professional
Primary
Secondary
Condition Aggravated Death 69 Female 10/19/2011 Other Health Professional Poland
Primary
Secondary
Hepatic Function Abnormal Other Serious 8/13/2010 41 Female 12/21/2011 Other Health Professional Japan
Primary
Concomitant
Bipolar I Disorder Hospitalization 11/30/2011 64 Female 134 lb 12/22/2011 Physician United States
Primary
Concomitant
Unevaluable Event Hospitalization 16 Female 1/4/2012 Physician Japan
Primary
Concomitant

Drug Data