Nplate combined with Rituxan

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Therapeutic Response Decreased Other Serious 10/21/2008 64 Male 190 lb 11/12/2008 Pharmacist United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 11/17/2008 Male 160 lb 4/13/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 11/17/2008 Male 160 lb 4/21/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 11/17/2008 Male 160 lb 4/24/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Female 6/5/2009 Physician United States
Primary
Concomitant
Tremor Other Serious 4/21/2009 Female 256 lb 6/23/2009 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 4/21/2009 Female 256 lb 6/30/2009 Physician United States
Primary
Secondary
Concomitant
Skin Haemorrhage Other Serious Female 117 lb 7/14/2009 Consumer United States
Primary
Concomitant
Fibrosis Other Serious 9/9/2009 62 Male 235 lb 10/4/2009 Other Health Professional United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious Male 195 lb 1/11/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious Male 240 lb 1/13/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/23/2009 Female 159 lb 2/8/2010 Physician United States
Primary
Concomitant
Sepsis Hospitalization 1/1/2009 Female 2/11/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/2/2009 Male 2/23/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/16/2010 Male 220 lb 2/23/2010 Pharmacist United States
Primary
Concomitant
Urticaria Other Serious 1/1/2009 Male 165 lb 2/26/2010 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/23/2009 Female 159 lb 3/3/2010 Physician United States
Primary
Concomitant
Thrombocytosis Other Serious Male 3/5/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/2/2009 Male 172 lb 3/16/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2009 Male 175 lb 3/25/2010 Physician United States
Primary
Concomitant
Myeloproliferative Disorder Other Serious Male 172 lb 3/26/2010 Physician United States
Primary
Concomitant
Pain Other Serious 1/1/2009 40 Female 210 lb 4/5/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2009 72 Female 190 lb 5/4/2010 Physician United States
Primary
Concomitant
Procedural Pain Other Serious 9/5/2009 67 Female 5/5/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2009 70 Female 146 lb 5/7/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2009 70 Female 146 lb 5/11/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2010 51 Female 158 lb 5/12/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 70 Female 146 lb 5/17/2010 Physician United States
Primary
Concomitant
Hypertension Other Serious 3/1/2009 83 Male 205 lb 5/21/2010 Physician United States
Primary
Concomitant
Urticaria Other Serious 1/1/2009 73 Male 165 lb 5/24/2010 Physician United States
Primary
Concomitant
Headache 9/1/2009 50 Male 170 lb 5/25/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 5/15/2009 34 Female 198 lb 5/25/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2009 72 Female 190 lb 5/28/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 5/1/2009 50 Male 170 lb 6/2/2010 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/26/2009 43 Female 220 lb 6/8/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2009 70 Female 146 lb 6/11/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2009 70 Female 146 lb 6/22/2010 Physician United States
Primary
Concomitant
Malaise Other Serious 6/7/2010 68 Male 238 lb 7/1/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2009 70 Female 146 lb 7/1/2010 Physician United States
Primary
Concomitant
Malaise Other Serious 6/7/2010 68 Male 238 lb 7/9/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2010 67 Male 237 lb 7/16/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 12/28/2009 84 Female 140 lb 7/21/2010 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Death Male 7/23/2010 Physician United States
Primary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2010 55 Male 196 lb 7/23/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/1/2010 69 Male 202 lb 7/27/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2010 67 Male 237 lb 7/28/2010 Physician United States
Primary
Concomitant
Syncope Other Serious 1/1/2010 55 Male 196 lb 8/4/2010 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Death 9/18/2009 72 Male 193 lb 8/4/2010 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/26/2009 43 Female 220 lb 8/27/2010 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Recurrent Other Serious Female 8/31/2010 Physician United States
Primary
Concomitant
Thrombocytosis Other Serious Male 9/1/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2009 50 Male 175 lb 9/3/2010 Physician United States
Primary
Concomitant
Urticaria Other Serious 1/1/2009 73 Male 165 lb 9/7/2010 Physician United States
Primary
Concomitant
Polymyalgia Rheumatica Other Serious 12/17/2009 73 Female 136 lb 9/10/2010 Physician United States
Primary
Concomitant
Pulmonary Thrombosis Other Serious 6/25/2010 66 Male 336 lb 9/15/2010 Physician United States
Primary
Concomitant
Platelet Count Increased Other Serious 6/8/2010 40 Male 270 lb 9/17/2010 Physician United States
Primary
Concomitant
Paroxysmal Nocturnal Haemoglobinuria Other Serious 1/1/2009 75 Male 9/22/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2010 65 Male 9/22/2010 Physician United States
Primary
Concomitant
Pulmonary Thrombosis Other Serious 6/25/2010 66 Male 336 lb 9/24/2010 Physician United States
Primary
Concomitant
Platelet Count Increased Other Serious 6/8/2010 40 Male 270 lb 9/29/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2010 65 Male 203 lb 10/7/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 10/21/2008 64 Male 190 lb 10/7/2010 Physician United States
Primary
Concomitant
Splenomegaly Other Serious 1/1/2010 49 Male 195 lb 10/13/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2010 52 Female 10/13/2010 Physician United States
Primary
Concomitant
Epistaxis Other Serious 11/3/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2009 11/22/2010 Physician United States
Primary
Concomitant
Dementia Hospitalization 11/22/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2010 11/30/2010 Physician United States
Primary
Concomitant
Platelet Destruction Increased Other Serious 2/17/2010 12/14/2010 Physician United States
Primary
Concomitant
Platelet Destruction Increased Other Serious 2/17/2010 12/17/2010 Physician United States
Primary
Concomitant
Pain Other Serious 12/30/2010 Physician United States
Primary
Concomitant
Pain Other Serious 12/31/2010 Physician United States
Primary
Concomitant
Fatigue Other Serious 1/14/2011 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 1/17/2011 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 4/16/2010 1/21/2011 Physician United States
Primary
Concomitant
Pulmonary Toxicity Hospitalization 5/30/2009 Male 1/25/2011 Physician United States
Primary
Secondary
Oedema Hospitalization 12/1/2010 71 Female 172 lb 2/8/2011 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 12/1/2010 71 Female 172 lb 2/15/2011 Physician United States
Primary
Concomitant
Depression Hospitalization 6/23/2009 58 Male 2/18/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2010 69 Male 2/23/2011 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 9/3/2010 30 Female 110 lb 2/24/2011 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/23/2009 58 Male 2/28/2011 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 3/18/2011 Physician United States
Primary
Concomitant
Alveolitis Hospitalization 3/30/2011 Consumer United States
Primary
Secondary
Cytomegalovirus Test Positive Other Serious 3/1/2011 36 Male 141 lb 4/5/2011 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 8/1/2009 Female 4/15/2011 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Other Serious 3/18/2011 Female 4/15/2011 Physician United States
Primary
Concomitant
Hypertension Other Serious 2/1/2011 70 Female 4/21/2011 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 8/1/2009 Female 4/25/2011 Physician United States
Primary
Concomitant
Fatigue Other Serious 3/14/2011 71 Female 148 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Cytomegalovirus Test Positive Other Serious 3/1/2011 36 Male 141 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Death Death Female 5/11/2011 Other Health Professional United States
Primary
Concomitant
Hospitalisation Hospitalization 4/11/2011 59 Male 5/11/2011 Physician United States
Primary
Concomitant
Cerebrovascular Accident Death 88 Female 118 lb 5/11/2011 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 3/1/2011 37 Male 141 lb 5/11/2011 Other Health Professional United States
Primary
Concomitant
Biopsy Bone Marrow Abnormal Other Serious Female 5/11/2011 Physician United States
Primary
Concomitant
Diabetes Insipidus Other Serious 2/17/2011 24 Male 5/12/2011 Physician United States
Primary
Concomitant
Hospitalisation Hospitalization 12/16/2010 79 Male 5/12/2011 Physician United States
Primary
Concomitant
Death Death Female 196 lb 5/13/2011 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 4/14/2011 72 Female 5/13/2011 Physician United States
Primary
Concomitant
Death Death 65 Female 154 lb 5/18/2011 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/1/2011 70 Female 5/18/2011 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 5/7/2011 69 Female 5/20/2011 Physician United States
Primary
Concomitant
Haemolysis Other Serious 46 Male 153 lb 6/2/2011 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious 3/18/2010 22 Female 6/3/2011 Physician United States
Primary
Concomitant
Medication Error Hospitalization 11/1/2010 Female 176 lb 6/6/2011 Physician Australia
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 3/18/2010 22 Female 183 lb 6/14/2011 Pharmacist United States
Primary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 3/1/2011 37 Male 141 lb 6/20/2011 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 3/1/2011 37 Male 141 lb 6/21/2011 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Other Serious 3/1/2011 37 Male 141 lb 6/23/2011 Other Health Professional United States
Primary
Concomitant
Medication Error Other Serious 5/18/2010 59 Male 197 lb 7/11/2011 Physician United States
Primary
Concomitant
Sepsis Hospitalization 1/1/2010 69 Male 7/13/2011 Physician United States
Primary
Concomitant
Medication Error Hospitalization 5/24/2011 60 Male 158 lb 7/19/2011 Physician United States
Primary
Concomitant
Biopsy Bone Marrow Abnormal Other Serious 6/28/2011 2 Male 7/22/2011 Physician United States
Primary
Concomitant
Death Death Male 7/22/2011 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 2/28/2011 81 Male 8/2/2011 Physician United States
Primary
Concomitant
Headache Hospitalization 1/1/2010 69 Male 243 lb 8/8/2011 Physician United States
Primary
Concomitant
Bile Duct Stone Hospitalization 2/28/2011 81 Male 8/11/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/1/2011 70 Female 8/12/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/1/2011 70 Female 8/16/2011 Physician United States
Primary
Concomitant
Myelofibrosis Death 2/1/2011 70 Female 8/19/2011 Physician United States
Primary
Concomitant
Therapeutic Response Delayed 1/1/2011 8/30/2011 Pharmacist United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2011 36 Male 8/30/2011 Physician United States
Primary
Concomitant
Bile Duct Stone Hospitalization 2/28/2011 81 Male 8/31/2011 Physician United States
Primary
Concomitant
Petechiae Other Serious 1/1/2011 87 Male 238 lb 9/20/2011 Physician United States
Primary
Concomitant
Dementia Alzheimer's Type Hospitalization Male 9/22/2011 Physician United States
Primary
Concomitant
Repetitive Speech Hospitalization 3/14/2011 71 Female 154 lb 9/30/2011 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Other Serious Female 10/3/2011 Pharmacist United States
Primary
Concomitant
Purpura Hospitalization 3/14/2011 71 Female 154 lb 10/5/2011 Physician United States
Primary
Concomitant
Petechiae Other Serious 6/23/2011 58 Female 10/5/2011 Physician United States
Primary
Concomitant
Haemolysis Other Serious 7/1/2011 74 Female 10/10/2011 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 187 lb 10/11/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Male 163 lb 10/11/2011 Other Health Professional United States
Primary
Concomitant
Petechiae Other Serious 58 Female 10/11/2011 Other Health Professional United States
Primary
Concomitant
Fatigue Hospitalization 7/1/2011 74 Female 10/12/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 9/21/2011 76 Male 163 lb 10/14/2011 Physician United States
Primary
Concomitant
Anxiety Other Serious Male 10/18/2011 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious Male 187 lb 10/21/2011 Physician United States
Primary
Concomitant
Gastritis Hospitalization 8/1/2011 21 Male 275 lb 10/31/2011 Physician United States
Primary
Concomitant
Osteoarthritis Hospitalization 9/2/2011 66 Female 231 lb 11/8/2011 Physician United States
Primary
Concomitant
Stasis Dermatitis Other Serious 1/1/2011 88 Male 238 lb 11/8/2011 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 8/17/2011 73 Male 187 lb 11/8/2011 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization Male 200 lb 11/10/2011 Physician United States
Primary
Concomitant
Arteriosclerosis Other Serious 9/2/2011 66 Female 231 lb 11/14/2011 Physician United States
Primary
Concomitant
Petechiae Other Serious 1/1/2011 88 Male 238 lb 11/21/2011 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 51 Male 315 lb 11/30/2011 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/1/2010 59 Male 269 lb 1/25/2012 Other Health Professional United States
Primary
Concomitant
Asthenia Death 5/19/2010 76 Female 182 lb 1/31/2012 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 2/4/2011 47 Male 220 lb 2/13/2012 Other Health Professional United States
Primary
Concomitant
Melaena Hospitalization 9/22/2010 34 Female 220 lb 2/23/2012 Physician United Kingdom
Primary
Secondary

Drug Data