Novantrone combined with Rebif

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oesophageal Ulcer Haemorrhage Hospitalization 12/1/2005 47 Female 2/1/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 11/1/2005 42 Female 2/13/2006 United States
Primary
Secondary
Pyrexia Hospitalization 1/7/2006 42 Female 2/17/2006 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 8/26/2005 49 Female 2/24/2006 United States
Primary
Secondary
Wheezing Hospitalization 1/1/2006 64 Male 150 lb 3/16/2006 United States
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 3/1/2006 59 Male 4/12/2006 United States
Primary
Concomitant
Overdose Hospitalization 10/30/2005 57 Female 4/14/2006 Physician United States
Primary
Secondary
Concomitant
Joint Injury Hospitalization 9/28/2005 58 Female 215 lb 4/14/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/21/2005 27 Female 4/26/2006 United States
Primary
Concomitant
Muscle Spasms Hospitalization 4/7/2006 45 Male 5/4/2006 Physician United States
Primary
Concomitant
Low Density Lipoprotein Increased Other Serious 3/24/2006 59 Male 191 lb 5/8/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 64 Male 150 lb 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/5/2006 42 Female 5/18/2006 United States
Primary
Secondary
Oedema Peripheral Hospitalization 5/4/2006 42 Female 5/24/2006 Consumer United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 4/12/2006 39 Female 132 lb 6/15/2006 United States
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 6/1/2005 36 Female 115 lb 4/13/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2005 42 Female 168 lb 6/19/2006 Physician United States
Primary
Secondary
Concomitant
Multiple Sclerosis Relapse Hospitalization 1/1/2005 42 Female 6/5/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/7/2006 42 Female 6/22/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/7/2006 42 Female 6/29/2006 Physician United States
Primary
Concomitant
Low Density Lipoprotein Increased Other Serious 3/24/2006 59 Male 191 lb 8/23/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2003 64 Male 153 lb 8/23/2006 United States
Primary
Concomitant
Pancytopenia Other Serious 8/1/2006 41 Female 9/21/2006 United States
Primary
Concomitant
Lymphoma Hospitalization 61 Male 10/10/2006 United States
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 8/1/2005 49 Female 109 lb 10/10/2006 Other Health Professional United States
Primary
Secondary
Tricuspid Valve Incompetence Other Serious 2/5/2002 38 Female 104 lb 10/17/2006 Physician United States
Primary
Concomitant
Suicide Attempt Other Serious 7/1/2005 36 Female 118 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 4/1/2006 54 Female 11/9/2006 Physician United States
Primary
Secondary
Pancytopenia Hospitalization 9/21/2006 61 Male 11/16/2006 Physician United States
Primary
Secondary
Pharyngolaryngeal Pain Hospitalization 8/1/2005 33 Female 11/27/2006 Physician United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 10/27/2006 54 Female 132 lb 12/4/2006 Physician United States
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 5/16/2006 45 Female 12/8/2006 Physician United States
Primary
Secondary
Concomitant
Sudden Death Life Threatening 6/18/2006 49 Female 12/8/2006 Physician United States
Primary
Secondary
Partial Seizures Other Serious 5/16/2006 45 Female 12/15/2006 Physician United States
Primary
Concomitant
Pancytopenia Other Serious 8/1/2006 41 Female 12/15/2006 United States
Primary
Concomitant
Cardiac Disorder Other Serious 55 Male 12/18/2006 United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 2/5/2002 38 Female 104 lb 12/19/2006 Physician United States
Primary
Concomitant
Sepsis Life Threatening 2/1/2006 43 Female 120 lb 12/22/2006 United States
Primary
Secondary
Concomitant
Pollakiuria Other Serious 1/15/2007 35 Female 200 lb 1/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 1/1/2006 42 Female 135 lb 2/2/2007 United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 12/1/2006 29 Female 2/5/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/1/2006 42 Female 120 lb 2/5/2007 United States
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 12/12/2005 33 Female 154 lb 2/5/2007 Other Health Professional United States
Primary
Concomitant
Shunt Occlusion Hospitalization 1/1/2006 21 Female 300 lb 2/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Promyelocytic Leukaemia Other Serious 12/1/2005 36 Female 2/12/2007 United States
Primary
Secondary
Concomitant
Pollakiuria Other Serious 1/15/2007 35 Female 200 lb 2/20/2007 United States
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 12/1/2004 42 Male 2/20/2007 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/13/2007 35 Male 2/20/2007 United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 10/27/2006 54 Female 132 lb 2/16/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/1/2006 55 Female 3/2/2007 United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 46 Female 3/15/2007 United States
Primary
Concomitant
Volvulus Hospitalization 65 Female 3/15/2007 Physician United States
Primary
Secondary
Convulsion Other Serious 12/5/2005 37 Male 3/12/2007 United States
Primary
Secondary
Hospitalisation Hospitalization 1/1/2006 44 Male 3/7/2007 United States
Primary
Secondary
Ejection Fraction Decreased Hospitalization 8/31/2006 47 Female 3/20/2007 United States
Primary
Secondary
Vomiting Hospitalization 1/1/2006 46 Female 4/16/2007 United States
Primary
Secondary
Hypersensitivity Hospitalization 11/24/2006 52 Female 4/13/2007 France
Primary
Concomitant
Sepsis Life Threatening 2/1/2006 43 Female 120 lb 4/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 8/8/2006 42 Female 135 lb 4/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/1/2006 46 Female 5/4/2007 Physician United States
Primary
Secondary
Concomitant
Drug Screen Positive Hospitalization 10/30/2005 57 Female 147 lb 5/8/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/1/2006 Female 5/11/2007 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 12/1/2006 29 Female 5/11/2007 Physician United States
Primary
Concomitant
Condition Aggravated Other Serious 26 Female 5/18/2007 United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 1/1/2007 35 Male 5/21/2007 United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 46 Female 118 lb 5/21/2007 United States
Primary
Concomitant
Fracture 26 Female 191 lb 5/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 1/24/2007 45 Female 198 lb 6/28/2007 Germany
Primary
Secondary
Coronary Artery Occlusion Other Serious 1/1/2007 56 Female 7/5/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2007 46 Female 155 lb 7/13/2007 United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 1/1/2006 56 Female 210 lb 7/23/2007 United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 7/1/2006 61 Male 175 lb 7/8/2007 Physician United States
Primary
Secondary
Stress Hospitalization 5/1/2007 49 Female 152 lb 8/17/2007 United States
Primary
Secondary
Concomitant
Partial Seizures Other Serious 5/16/2006 45 Female 8/30/2007 Physician United States
Primary
Secondary
Concomitant
Splenic Rupture Other Serious 1/1/2007 50 Female 9/7/2007 United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 56 Female 137 lb 9/7/2007 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/1/2007 54 Female 9/14/2007 United States
Primary
Secondary
Thrombosis Life Threatening 1/24/2007 45 Female 207 lb 9/21/2007 Other Health Professional Germany
Primary
Secondary
Viral Infection Other Serious 1/1/2007 58 Female 154 lb 9/27/2007 United States
Primary
Secondary
Viral Infection Other Serious 6/7/2007 58 Female 170 lb 10/3/2007 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/1/2007 62 Female 131 lb 10/4/2007 United States
Primary
Secondary
Musculoskeletal Pain Death 1/1/2005 45 Female 10/17/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2007 41 Female 10/26/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/1/2007 41 Female 11/9/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 49 Female 175 lb 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 1/1/2007 65 Male 12/14/2007 United States
Primary
Secondary
Urinary Tract Infection Hospitalization 11/19/2007 43 Male 160 lb 12/18/2007 United States
Primary
Secondary
Concomitant
Immunosuppression Hospitalization 11/19/2007 43 Male 160 lb 1/11/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 7/20/2007 43 Male 160 lb 1/11/2008 Consumer United States
Primary
Concomitant
Implantable Defibrillator Insertion Other Serious 55 Male 1/16/2008 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/10/2004 52 Female 134 lb 1/16/2008 Other Health Professional United States
Primary
Concomitant
No Therapeutic Response Hospitalization 1/1/2006 64 Female 2/1/2008 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 2/5/2002 35 Female 104 lb 2/27/2008 Physician United States
Primary
Concomitant
Fatigue Other Serious 1/31/2008 50 Female 3/5/2008 United States
Primary
Secondary
Concomitant
Motor Neurone Disease Hospitalization 64 Female 3/3/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/1/2007 41 Female 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 1/1/2008 44 Female 4/11/2008 United States
Primary
Secondary
Ejection Fraction Decreased Other Serious 4/1/2008 44 Female 185 lb 4/23/2008 United States
Primary
Secondary
Concomitant
Death Death 8/1/2007 59 Female 4/30/2008 Consumer United States
Primary
Concomitant
Nephrolithiasis Hospitalization 7/1/2007 54 Female 220 lb 4/29/2008 United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 1/13/2007 46 Female 118 lb 5/5/2008 United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 56 Female 137 lb 5/6/2008 Physician United States
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 1/1/2007 45 Female 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2008 61 Female 5/22/2008 United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 1/1/2005 52 Female 210 lb 6/2/2008 United States
Primary
Secondary
Feeling Hot Death 6/7/2008 38 Female 6/17/2008 Physician United States
Primary
Secondary
Pneumonia Hospitalization 1/1/2008 47 Female 6/19/2008 United States
Primary
Secondary
Ejection Fraction Decreased Other Serious 1/1/2007 53 Female 1788 lb 6/24/2008 United States
Primary
Secondary
Wheelchair User Other Serious 7/1/2007 54 Female 6/24/2008 Physician United States
Primary
Secondary
Therapeutic Response Decreased Hospitalization 1/1/2008 47 Female 175 lb 7/10/2008 United States
Primary
Secondary
Concomitant
Osteoporosis Disability 1/1/2008 60 Female 7/21/2008 Physician Germany
Primary
Concomitant
Raynaud's Phenomenon Disability 1/1/2008 60 Female 7/29/2008 Physician Germany
Primary
Concomitant
Convulsion Other Serious 4/15/2008 44 Female 7/31/2008 United States
Primary
Secondary
Concomitant
Rectocele Other Serious 1/1/2008 45 Female 225 lb 8/7/2008 United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 4/1/2008 44 Female 185 lb 8/11/2008 United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 1/1/2005 52 Female 210 lb 8/20/2008 United States
Primary
Secondary
Cholelithiasis Other Serious 39 Female 8/25/2008 United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 1/31/2008 50 Female 155 lb 9/16/2008 United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2007 47 Female 9/18/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 9/18/2008 65 Male 9/29/2008 United States
Primary
Secondary
Hypotension Other Serious 1/1/2008 56 Female 146 lb 10/2/2008 United States
Primary
Secondary
Concomitant
Mass Other Serious 1/1/2005 52 Female 209 lb 10/10/2008 Physician United States
Primary
Secondary
Pulmonary Embolism Hospitalization 4/1/2008 29 Female 10/17/2008 United States
Primary
Secondary
Status Epilepticus Other Serious 1/1/2007 45 Female 10/22/2008 Physician United States
Primary
Secondary
Concomitant
Hypotension Other Serious 3/16/2006 54 Female 150 lb 10/28/2008 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/1/2007 29 Female 10/28/2008 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 2/5/2002 35 Female 104 lb 11/10/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2008 58 Female 181 lb 11/6/2008 United States
Primary
Secondary
Concomitant
Immobile Death 9/18/2008 65 Male 11/7/2008 United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 1/1/2008 58 Female 11/10/2008 United States
Primary
Secondary
Pain Death 11/1/2005 45 Female 11/14/2008 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 1/1/2008 58 Female 229 lb 11/18/2008 United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 41 Female 11/21/2008 United States
Primary
Secondary
Thrombosis Hospitalization 1/1/2008 58 Female 240 lb 12/1/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/1/2007 41 Female 12/3/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/1/2007 41 Female 12/3/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2008 47 Female 176 lb 12/12/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/1/2006 34 Female 12/5/2008 United States
Primary
Secondary
Weight Bearing Difficulty Hospitalization 1/1/2008 58 Female 240 lb 1/27/2009 United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 4/1/2008 44 Female 185 lb 1/28/2009 Physician United States
Primary
Secondary
Concomitant
Breast Cancer Hospitalization 2/1/2008 48 Female 168 lb 2/26/2009 Physician United States
Primary
Secondary
Vitamin D Abnormal 47 Female 174 lb 3/19/2009 United States
Primary
Concomitant
Mass Other Serious 1/1/2005 52 Female 209 lb 3/27/2009 Other Health Professional United States
Primary
Secondary
Benign Neoplasm Of Thyroid Gland Other Serious 1/1/2009 44 Male 4/23/2009 United States
Primary
Secondary
Concomitant
Vulval Disorder Hospitalization 4/1/2008 46 Female 143 lb 5/1/2009 United States
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 1/1/2009 44 Male 170 lb 5/5/2009 United States
Primary
Secondary
Concomitant
Tubal Rupture Other Serious 1/1/2009 35 Female 5/14/2009 United States
Primary
Concomitant
Multiple Sclerosis Relapse 5/1/2008 35 Female 207 lb 5/11/2009 United States
Primary
Concomitant
Headache Other Serious 5/10/1998 28 Female 6/22/2009 Consumer United States
Primary
Concomitant
Fall Hospitalization 5/1/2009 49 Male 271 lb 6/16/2009 Consumer United States
Primary
Secondary

Drug Data