Norvasc combined with Sunitinib Malate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Hospitalization 10/16/2006 Female 116 lb 8/17/2007 United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 54 Female 12/22/2007 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 54 Female 1/10/2008 Physician United States
Primary
Concomitant
Intussusception Death 10/20/2007 56 Male 2/13/2008 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 54 Female 2/21/2008 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 10/17/2007 56 Male 2/28/2008 Physician United States
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 6/13/2007 Male 5/29/2008 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 8/8/2007 Male 193 lb 7/31/2008 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 5/2/2008 Male 320 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 5/2/2008 Male 320 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Hypertension Hospitalization 8/22/2008 Female 90 lb 12/16/2008 Physician Italy
Primary
Concomitant
Urticaria Hospitalization 9/29/2008 12/17/2008 Physician Japan
Primary
Secondary
Concomitant
Urticaria Other Serious 9/19/2008 12/31/2008 Physician Japan
Primary
Secondary
Concomitant
Transitional Cell Carcinoma Hospitalization 10/5/2008 Male 196 lb 1/14/2009 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 9/30/2008 1/26/2009 Physician Japan
Primary
Concomitant
Hypertension Other Serious 5/10/2008 Female 115 lb 1/27/2009 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 11/14/2008 2/11/2009 Physician Japan
Primary
Concomitant
Sinus Disorder Hospitalization 8/8/2007 Male 193 lb 2/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/6/2008 Male 187 lb 2/18/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/5/2008 Male 379 lb 2/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Haemothorax Other Serious 10/3/2008 2/25/2009 Physician Japan
Primary
Concomitant
Hepatic Infection Bacterial Hospitalization 11/23/2007 Female 134 lb 3/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 8/28/2006 3/9/2009 Physician Italy
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 2/27/2009 3/20/2009 Physician Japan
Primary
Concomitant
Haemothorax Other Serious 10/2/2008 3/20/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/13/2009 4/3/2009 Physician Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 8/28/2006 4/3/2009 Physician Italy
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 1/28/2009 4/6/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 11/14/2008 4/7/2009 Physician Japan
Primary
Secondary
Concomitant
Gingival Infection Life Threatening 2/14/2009 4/14/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/13/2009 4/17/2009 Physician Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 2/27/2009 4/20/2009 Physician Japan
Primary
Concomitant
Hepatic Infection Bacterial Hospitalization 11/23/2007 Female 134 lb 4/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Other Serious 5/10/2008 Female 115 lb 4/21/2009 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 11/14/2008 4/27/2009 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 11/28/2008 4/27/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/13/2009 4/30/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/13/2009 43 5/8/2009 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Hospitalization 8/2/2006 75 5/12/2009 Physician Germany
Primary
Concomitant
Urosepsis Hospitalization 6/14/2005 Female 137 lb 5/13/2009 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 11/28/2008 66 5/18/2009 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 1/20/2006 Female 123 lb 5/22/2009 United States
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 9/19/2008 67 6/3/2009 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 4/21/2009 77 6/10/2009 Physician Japan
Primary
Concomitant
Cholecystitis Hospitalization 8/28/2008 77 6/15/2009 Physician Korea, Republic Of
Primary
Concomitant
Pyrexia Other Serious 1/1/2009 70 6/23/2009 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 4/21/2009 77 6/29/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 1/28/2009 62 6/30/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 3/16/2009 70 7/6/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Other Serious 4/6/2009 67 7/7/2009 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Other Serious 9/30/2008 59 7/7/2009 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 4/14/2009 58 7/13/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 2/20/2009 59 7/15/2009 Pharmacist Japan
Primary
Concomitant
Renal Cell Carcinoma Other Serious 9/19/2008 67 7/17/2009 Physician Japan
Primary
Concomitant
Memory Impairment Other Serious 5/10/2008 Female 115 lb 7/21/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Life Threatening 3/2/2009 67 7/22/2009 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 6/13/2009 51 7/24/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Pyrexia Hospitalization 2/20/2009 59 7/28/2009 Pharmacist Japan
Primary
Concomitant
Hypothyroidism Other Serious 6/6/2009 69 Male 141 lb 8/4/2009 Physician United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 4/14/2009 58 8/5/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 3/2/2009 67 8/5/2009 Physician Japan
Primary
Concomitant
Sudden Death Death 4/8/2007 Female 231 lb 8/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Complication Hospitalization 10/22/2005 Male 284 lb 8/11/2009 Other Health Professional United States
Primary
Concomitant
Hypertension Other Serious 5/10/2008 Female 115 lb 8/18/2009 Other Health Professional United States
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 10/22/2005 Male 284 lb 8/18/2009 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 4/6/2009 67 8/19/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 11/14/2008 53 8/19/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/10/2008 66 8/21/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 9/6/2008 Male 187 lb 8/24/2009 Physician United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 9/30/2008 59 8/27/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/10/2008 66 8/31/2009 Physician Japan
Primary
Concomitant
Mouth Ulceration Hospitalization 6/13/2007 Male 9/7/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 7/28/2004 Male 219 lb 9/16/2009 Other Health Professional United States
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 10/22/2005 Male 285 lb 9/17/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/22/2009 78 10/16/2009 Physician Japan
Primary
Concomitant
Paralysis Hospitalization 4/16/2006 67 10/16/2009 Other Health Professional Italy
Primary
Concomitant
Hypertension Other Serious 5/10/2008 Female 115 lb 10/20/2009 Other Health Professional United States
Primary
Concomitant
Cerebellar Infarction Hospitalization 3/9/2006 Female 140 lb 11/3/2009 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 4/6/2009 67 Male 93 lb 11/9/2009 Physician Japan
Primary
Concomitant
Hypothyroidism Hospitalization 3/8/2007 Male 262 lb 11/9/2009 Other Health Professional United States
Primary
Concomitant
Mouth Ulceration Hospitalization 6/13/2007 Male 11/11/2009 Physician United States
Primary
Concomitant
Pneumonitis Hospitalization 7/13/2009 41 Female 141 lb 11/12/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 5/9/2006 71 Male 172 lb 11/13/2009 Physician Germany
Primary
Concomitant
Blood Bilirubin Increased Hospitalization 7/31/2009 65 Male 129 lb 11/17/2009 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 6/13/2009 51 Male 165 lb 11/16/2009 Physician Taiwan, Province Of China
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/20/2009 59 Female 98 lb 11/23/2009 Physician Japan
Primary
Concomitant
Suicide Attempt Other Serious 10/2/2008 59 Male 161 lb 11/27/2009 Physician Japan
Primary
Concomitant
Lacunar Infarction Hospitalization 9/18/2009 70 Male 11/27/2009 Physician Japan
Primary
Concomitant
Metabolic Disorder Hospitalization 8/8/2007 Male 193 lb 11/30/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/10/2008 66 Female 139 lb 12/11/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 10/27/2009 75 Female 101 lb 12/15/2009 Physician Japan
Primary
Concomitant
Fatigue Hospitalization 2/2/2008 Male 214 lb 12/15/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 167 lb 12/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 11/27/2009 75 Female 101 lb 12/18/2009 Physician Japan
Primary
Concomitant
Lacunar Infarction Hospitalization 9/18/2009 70 12/21/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 9/28/2009 77 Male 137 lb 12/30/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 11/25/2009 75 Female 101 lb 1/5/2010 Physician Japan
Primary
Concomitant
Oesophagitis Other Serious 12/11/2006 Male 161 lb 1/4/2010 Physician Malaysia
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/10/2008 66 Female 139 lb 1/8/2010 Physician Japan
Primary
Concomitant
Cerebellar Infarction Hospitalization 3/9/2006 Female 140 lb 1/14/2010 Other Health Professional United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 12/31/2009 Male 170 lb 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 12/20/2009 36 Female 112 lb 1/15/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Lacunar Infarction Hospitalization 9/18/2009 70 Male 1/20/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/17/2009 45 Male 116 lb 2/9/2010 Physician Japan
Primary
Concomitant
Blood Sodium Decreased Other Serious 1/19/2010 Female 172 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Aphasia Other Serious 6/23/2009 79 Male 106 lb 2/19/2010 Physician Japan
Primary
Concomitant
Mental Status Changes Hospitalization 2/8/2010 Female 192 lb 2/22/2010 Physician United States
Primary
Secondary
Concomitant
Dysphagia Other Serious 6/23/2009 79 Male 106 lb 2/23/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/17/2009 45 Male 116 lb 3/3/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 2/10/2007 69 Female 140 lb 3/9/2010 Physician Italy
Primary
Concomitant
Mental Status Changes Hospitalization 3/8/2010 Female 172 lb 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 3/28/2010 Male 240 lb 3/30/2010 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Upper Other Serious 6/25/2006 66 Male 163 lb 3/30/2010 Physician Germany
Primary
Concomitant
Bone Marrow Failure Other Serious 7/29/2009 77 Male 140 lb 2/15/2010 Physician United States
Primary
Concomitant
Mental Status Changes Hospitalization 2/8/2010 59 Female 192 lb 4/12/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 12/18/2009 82 Female 125 lb 4/12/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/15/2009 67 Male 132 lb 4/20/2010 Physician Japan
Primary
Secondary
Concomitant
Overdose Hospitalization 2/8/2010 59 Female 192 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 8/5/2008 59 Male 379 lb 4/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 9/14/2009 82 Female 125 lb 5/5/2010 Physician Japan
Primary
Concomitant
Thyroiditis Other Serious 57 Female 132 lb 5/5/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 2/23/2009 50 Female 98 lb 5/5/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/15/2009 67 Male 132 lb 5/5/2010 Physician Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization 2/17/2010 79 Male 5/5/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/18/2008 72 Female 101 lb 5/12/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 4/7/2010 62 Male 5/19/2010 Pharmacist Japan
Primary
Concomitant
Renal Failure Life Threatening 4/5/2010 62 Male 179 lb 5/26/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Vascular Insufficiency Hospitalization 2/20/2009 59 Male 162 lb 5/28/2010 Physician Japan
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 7/16/2009 65 Male 100 lb 6/1/2010 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 9/19/2009 64 Male 87 lb 5/31/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/2/2010 42 Male 192 lb 6/3/2010 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Life Threatening 9/14/2009 82 Female 125 lb 6/3/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 9/25/2008 66 Female 101 lb 6/3/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/20/2009 59 Female 98 lb 6/4/2010 Physician Japan
Primary
Concomitant
Nephrotic Syndrome Hospitalization 2/17/2010 79 Male 6/4/2010 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 10/30/2008 59 Male 143 lb 6/8/2010 Physician Japan
Primary
Concomitant
Hepatitis Hospitalization 8/2/2006 75 Female 187 lb 6/9/2010 Physician Germany
Primary
Concomitant
Platelet Count Decreased Other Serious 8/18/2008 72 Female 101 lb 6/11/2010 Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 8/11/2008 81 Female 114 lb 6/14/2010 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 9/19/2009 64 Male 87 lb 6/25/2010 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Other Serious 9/25/2008 66 Female 101 lb 6/25/2010 Japan
Primary
Concomitant
Pyrexia Hospitalization 10/30/2008 59 Male 143 lb 6/28/2010 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 2/20/2009 59 Male 162 lb 6/30/2010 Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/18/2008 72 Female 101 lb 7/2/2010 Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/15/2009 67 Male 132 lb 7/7/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/23/2009 50 Female 98 lb 7/8/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 12/14/2009 60 Male 134 lb 7/14/2010 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 9/19/2009 64 Male 87 lb 7/26/2010 Physician Japan
Primary
Concomitant
Death Death 4/15/2010 80 Male 7/27/2010 Physician Japan
Primary
Concomitant
Hypertension Other Serious 5/10/2008 82 Female 115 lb 7/27/2010 Other Health Professional United States
Primary
Concomitant

Drug Data