Norvasc combined with Sorafenib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Hospitalization 12/22/2005 68 Male 262 lb 1/10/2006 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 8/9/2005 57 Male 272 lb 1/10/2006 Physician United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Death 12/24/2005 71 Male 175 lb 1/10/2006 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 12/19/2005 84 Male 215 lb 1/27/2006 United States
Primary
Concomitant
Troponin Increased Other Serious 12/27/2005 63 Male 159 lb 2/8/2006 United States
Primary
Concomitant
Troponin Increased Other Serious 12/27/2005 63 Male 159 lb 2/10/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/22/2005 68 Male 262 lb 2/9/2006 United States
Primary
Concomitant
Troponin Increased Other Serious 12/27/2005 63 Male 159 lb 2/20/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/27/2005 63 Male 159 lb 3/3/2006 United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/27/2005 63 Male 159 lb 3/8/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/27/2005 63 Male 159 lb 3/15/2006 Physician United States
Primary
Concomitant
Peptic Ulcer Haemorrhage Life Threatening 5/7/2006 54 Male 143 lb 5/16/2006 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 2/9/2006 62 Male 155 lb 5/19/2006 United States
Primary
Concomitant
Skin Exfoliation Hospitalization 2/9/2006 62 Male 155 lb 5/30/2006 Consumer United States
Primary
Concomitant
Nausea Life Threatening 5/7/2006 54 Male 143 lb 5/26/2006 United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 2/8/2006 76 Female 179 lb 6/2/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/12/2006 60 Male 141 lb 6/6/2006 Physician United States
Primary
Concomitant
Pruritus 1/10/2006 59 Male 4/24/2006 United States
Primary
Concomitant
Speech Disorder Hospitalization 6/12/2006 78 Female 174 lb 6/22/2006 Canada
Primary
Concomitant
Sarcoidosis Hospitalization 56 Female 7/31/2006 Consumer Germany
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 8/8/2006 Physician Canada
Primary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 8/8/2006 Canada
Primary
Concomitant
Pyrexia Other Serious 7/11/2006 46 Male 205 lb 8/24/2006 Australia
Primary
Concomitant
Pyrexia Other Serious 9/7/2005 45 Male 205 lb 8/29/2006 Australia
Primary
Concomitant
Hypophosphataemia Hospitalization 8/8/2006 82 Male 128 lb 8/30/2006 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 12/19/2005 85 Male 216 lb 9/5/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/27/2005 63 Male 159 lb 9/12/2006 Physician United States
Primary
Concomitant
Sarcoidosis Disability 7/14/2006 56 Female 9/14/2006 Physician Germany
Primary
Secondary
Concomitant
Hypophosphataemia Other Serious 8/8/2006 82 Male 128 lb 9/19/2006 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/10/2006 64 Male 128 lb 9/21/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Urinary Tract Infection Other Serious 9/10/2006 64 Male 128 lb 9/27/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 5/7/2006 54 Male 143 lb 10/3/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 9/10/2006 64 Male 128 lb 10/4/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Sarcoidosis Hospitalization 4/16/2006 56 Female 10/6/2006 Physician Germany
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 5/7/2006 54 Male 143 lb 10/9/2006 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 2/9/2006 63 Male 154 lb 10/11/2006 Physician United States
Primary
Concomitant
Speech Disorder Hospitalization 6/12/2006 78 Female 174 lb 10/12/2006 Physician Canada
Primary
Concomitant
Haemoglobin Decreased Life Threatening 9/13/2005 53 Male 143 lb 10/17/2006 Physician United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 12/19/2005 85 Male 216 lb 10/18/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 10/18/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 10/24/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 9/7/2005 45 Male 205 lb 10/31/2006 Australia
Primary
Concomitant
Skin Ulcer Hospitalization 2/9/2006 63 Male 154 lb 11/2/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/10/2006 64 Male 128 lb 11/7/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Skin Ulcer Hospitalization 2/9/2006 63 Male 154 lb 11/7/2006 Physician United States
Primary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 9/7/2005 45 Male 205 lb 11/16/2006 Australia
Primary
Concomitant
Vision Blurred Hospitalization 8/9/2005 57 Male 271 lb 12/1/2006 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 8/9/2005 57 Male 271 lb 12/6/2006 Physician United States
Primary
Secondary
Concomitant
Hemiparesis Life Threatening 12/9/2006 59 Female 170 lb 12/19/2006 Physician China
Primary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 12/21/2006 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 12/21/2006 Physician United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Death 72 Male 174 lb 12/22/2006 Physician United States
Primary
Concomitant
Duodenal Ulcer Haemorrhage Life Threatening 9/10/2005 53 Male 143 lb 12/29/2006 Physician United States
Primary
Concomitant
Pyrexia Other Serious 9/7/2005 45 Male 205 lb 1/16/2007 Australia
Primary
Concomitant
Dry Skin Male 11/6/2006 United States
Primary
Concomitant
Weight Decreased 1/10/2006 59 Male 203 lb 10/23/2006 United States
Primary
Concomitant
Hypoxia Hospitalization 1/3/2007 53 Male 126 lb 1/19/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 1/23/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 1/3/2007 53 Male 126 lb 1/24/2007 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/3/2007 53 Male 126 lb 1/26/2007 Physician United States
Primary
Concomitant
Skin Ulcer Disability 7/18/2006 56 Female 2/26/2007 Physician Germany
Primary
Secondary
Concomitant
Wheezing Hospitalization 8/18/2005 67 Male 238 lb 3/29/2007 Physician United States
Primary
Concomitant
Gastroenteritis Hospitalization 3/9/2007 66 Male 168 lb 3/30/2007 Physician Netherlands
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 4/2/2007 Physician United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 3/26/2007 71 Female 130 lb 4/13/2007 Physician United States
Primary
Concomitant
Skin Ulcer Disability 7/18/2006 56 Female 4/20/2007 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/7/2007 71 Male 154 lb 4/30/2007 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 5/3/2007 66 Female 117 lb 5/25/2007 Physician Germany
Primary
Concomitant
Hypercreatininaemia Hospitalization 5/18/2007 69 Male 137 lb 6/4/2007 Physician Canada
Primary
Concomitant
Thrombocytopenia Life Threatening 7/16/2007 76 Male 174 lb 7/27/2007 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/18/2007 69 Male 137 lb 7/31/2007 Physician Canada
Primary
Concomitant
Weight Decreased 1/10/2006 59 Male 203 lb 8/1/2007 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 7/16/2007 76 Male 174 lb 10/19/2007 Physician Germany
Primary
Secondary
Concomitant
Pruritus 1/1/2005 45 Female 10/12/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 11/16/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 1/3/2007 53 Male 126 lb 12/10/2007 Physician United States
Primary
Concomitant
Gastric Ulcer Hospitalization 5/3/2007 66 Female 117 lb 12/20/2007 Physician Germany
Primary
Concomitant
Restlessness Hospitalization 12/20/2007 74 Female 187 lb 1/3/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 1/22/2008 Physician United States
Primary
Secondary
Concomitant
Renal Infarct Hospitalization 10/28/2007 61 Female 172 lb 2/12/2008 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 1/29/2008 Female 2/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Peripheral Motor Neuropathy Other Serious 12/25/2007 76 Male 2/26/2008 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 2/22/2008 Male 127 lb 2/25/2008 Other Health Professional United States
Primary
Concomitant
Restlessness Hospitalization 12/20/2007 74 Female 187 lb 3/6/2008 United States
Primary
Secondary
Concomitant
Restlessness Hospitalization 12/20/2007 74 Female 187 lb 3/20/2008 United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 12/25/2007 76 Male 4/7/2008 Physician United States
Primary
Secondary
Concomitant
Skin Lesion 1/1/2005 48 Male 150 lb 5/2/2008 Consumer United States
Primary
Concomitant
Sudden Death Death 3/27/2008 59 Male 190 lb 6/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2007 70 Male 137 lb 7/8/2008 Physician Canada
Primary
Concomitant
Peritonitis Hospitalization 7/5/2008 74 Female 161 lb 7/22/2008 Physician Italy
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 5/2/2008 Male 320 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 5/2/2008 Male 320 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2007 70 Male 137 lb 8/15/2008 Physician Canada
Primary
Concomitant
Peritonitis Hospitalization 7/5/2008 74 Female 161 lb 8/22/2008 Physician Italy
Primary
Secondary
Concomitant
Peripheral Motor Neuropathy Other Serious 12/25/2007 76 Male 9/18/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/5/2006 72 Female 10/3/2008 United States
Primary
Concomitant
Urinary Incontinence Hospitalization 10/1/2008 77 Male 187 lb 10/30/2008 Physician Canada
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 10/1/2008 77 Male 187 lb 11/25/2008 Physician Canada
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 10/1/2008 77 Male 187 lb 12/2/2008 Physician Canada
Primary
Secondary
Concomitant
Wound Infection Hospitalization 10/28/2007 61 Female 176 lb 12/10/2008 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Hospitalization 10/28/2007 61 Female 176 lb 12/15/2008 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Hospitalization 10/28/2007 61 Female 176 lb 12/18/2008 Physician Germany
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 10/1/2008 77 Male 187 lb 12/23/2008 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Thrombosis Other Serious 2/4/2009 79 Male 168 lb 2/10/2009 Physician Greece
Primary
Secondary
Concomitant
Electrocardiogram Abnormal Other Serious 1/30/2009 37 Male 172 lb 2/11/2009 Physician Italy
Primary
Concomitant
Regurgitation Hospitalization 1/1/2009 67 Male 143 lb 3/16/2009 Other Health Professional Canada
Primary
Concomitant
Urinary Incontinence Hospitalization 10/1/2008 77 Male 187 lb 3/25/2009 Physician Canada
Primary
Secondary
Concomitant
Peripheral Motor Neuropathy Other Serious 12/25/2007 76 Male 161 lb 3/30/2009 Physician United States
Primary
Secondary
Concomitant
Electrocardiogram Abnormal Other Serious 1/30/2009 37 Male 172 lb 4/1/2009 Physician Italy
Primary
Concomitant
Regurgitation Hospitalization 1/1/2009 67 Male 143 lb 4/2/2009 Other Health Professional Canada
Primary
Concomitant
Urine Leukocyte Esterase Positive Other Serious 12/25/2007 76 Male 161 lb 4/3/2009 Physician United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 3/16/2009 81 Male 4/9/2009 Physician Italy
Primary
Concomitant
Lymphopenia Hospitalization 2/20/2009 81 Male 143 lb 4/21/2009 Physician Italy
Primary
Concomitant
Diarrhoea Hospitalization 4/11/2009 80 Female 150 lb 4/24/2009 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 4/30/2008 85 Male 148 lb 4/24/2009 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 4/11/2009 80 Female 150 lb 5/8/2009 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/14/2009 58 Female 120 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Skin Exfoliation Hospitalization 5/22/2009 67 Female 194 lb 5/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Hospitalization 5/21/2009 68 Female 194 lb 6/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/22/2009 67 Female 194 lb 6/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/21/2009 68 Female 194 lb 6/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ascites Hospitalization 6/23/2009 59 Male 128 lb 7/22/2009 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/21/2009 68 Female 194 lb 7/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ascites Hospitalization 6/23/2009 59 Male 128 lb 8/4/2009 Physician United States
Primary
Concomitant
Lymphopenia Hospitalization 2/20/2009 81 Male 143 lb 8/11/2009 Physician Italy
Primary
Concomitant
Electrocardiogram Abnormal Other Serious 1/30/2009 37 Male 172 lb 8/17/2009 Physician Italy
Primary
Concomitant
Pain In Extremity Other Serious 12/25/2007 76 Male 161 lb 8/18/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/21/2009 Male 166 lb 9/23/2009 Consumer United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 3/26/2007 71 Female 130 lb 11/4/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 4/30/2008 85 Male 148 lb 11/20/2009 Physician Germany
Primary
Secondary
Concomitant
Femoral Pulse Decreased Other Serious 10/7/2009 78 Male 194 lb 11/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 12/14/2009 80 Female 119 lb 1/12/2010 Physician Japan
Primary
Concomitant
Pain In Extremity Other Serious 9/29/2009 78 Male 194 lb 2/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/3/2010 63 Male 2/12/2010 Physician Germany
Primary
Concomitant
Pain In Extremity Other Serious 9/29/2009 78 Male 194 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/28/2010 56 Male 2/24/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/4/2010 63 Male 2/25/2010 Physician Germany
Primary
Concomitant
Pain In Extremity Other Serious 9/29/2009 78 Male 194 lb 3/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Procedural Complication Other Serious 3/2/2010 59 Male 3/26/2010 Physician Canada
Primary
Concomitant
Procedural Complication Other Serious 3/2/2010 59 Male 4/12/2010 Physician Canada
Primary
Concomitant
Respiratory Disorder Hospitalization 2/18/2010 60 Male 204 lb 4/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Regurgitation Hospitalization 1/1/2009 67 Male 143 lb 4/14/2010 Germany
Primary
Concomitant
Glomerular Filtration Rate Decreased Hospitalization 1/26/2010 60 Male 205 lb 4/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/11/2009 80 Female 139 lb 4/21/2010 Physician United States
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Other Serious 9/29/2009 78 Male 194 lb 4/21/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Hypoxia Hospitalization 4/11/2009 80 Female 139 lb 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Hypoxia Hospitalization 4/11/2009 80 Female 139 lb 5/18/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/11/2009 80 Female 132 lb 6/7/2010 Physician United States
Primary
Secondary
Concomitant

Drug Data