Norvasc combined with Pravastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Life Threatening 9/30/2005 83 Female 1/3/2006 Physician Japan
Primary
Secondary
Concomitant
Respiration Abnormal Life Threatening 9/30/2005 83 Female 1/9/2006 Physician Japan
Primary
Secondary
Concomitant
Somnolence Life Threatening 9/30/2005 83 Female 1/16/2006 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 9/14/2005 82 Male 190 lb 1/23/2006 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 10/20/2005 71 Male 2/8/2006 Japan
Primary
Concomitant
Therapy Non-responder Hospitalization 7/1/2004 71 Female 2/24/2006 Japan
Primary
Secondary
Peroneal Nerve Palsy Other Serious 62 Female 2/28/2006 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/1/2006 75 Female 3/6/2006 Pharmacist Japan
Primary
Concomitant
Tachypnoea Life Threatening 9/30/2005 83 Female 3/8/2006 Physician Japan
Primary
Secondary
Concomitant
Fall Death 3/4/2006 78 Female 3/9/2006 Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/1/2006 70 Female 3/15/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/1/2006 70 Female 3/15/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 3/3/2006 78 Female 3/23/2006 Japan
Primary
Concomitant
Serum Ferritin Increased Hospitalization 7/1/2004 71 Female 3/16/2006 Japan
Primary
Secondary
Sudden Death Death 3/3/2006 78 Female 4/13/2006 Japan
Primary
Concomitant
Pain Other Serious 5/8/2006 73 Female 93 lb 6/21/2006 Physician Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 4/13/2006 61 Male 161 lb 6/23/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/10/2006 75 Male 7/5/2006 Physician Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 4/13/2006 61 Male 161 lb 7/13/2006 Physician Japan
Primary
Secondary
Concomitant
Swelling Other Serious 5/8/2006 73 Female 93 lb 7/26/2006 Physician Japan
Primary
Concomitant
Treatment Noncompliance Hospitalization 4/13/2006 61 Male 161 lb 9/18/2006 Physician Japan
Primary
Secondary
Concomitant
Sinus Arrest Other Serious 9/19/2006 85 Female 10/9/2006 Physician Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 6/6/2006 85 Female 10/23/2006 Physician Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 6/6/2006 85 Female 10/31/2006 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/24/2006 61 Male 12/4/2006 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 8/13/2006 87 Female 12/5/2006 Physician Japan
Primary
Concomitant
Protein Urine Present Other Serious 68 Female 12/6/2006 Physician Japan
Primary
Concomitant
Oral Intake Reduced Hospitalization 5/1/2006 67 Male 12/8/2006 Physician Netherlands
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 11/22/2006 61 Male 12/11/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/2/2006 78 Female 12/21/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 11/22/2006 61 Male 12/14/2006 Physician Japan
Primary
Secondary
Concomitant
Nasopharyngitis Life Threatening 11/13/2006 61 Male 150 lb 12/20/2006 Physician Japan
Primary
Concomitant
Pruritus Hospitalization 8/13/2006 87 Female 82 lb 12/20/2006 Physician Japan
Primary
Concomitant
Nasopharyngitis Life Threatening 11/13/2006 61 Male 150 lb 12/22/2006 Physician Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 8/13/2006 87 Female 82 lb 12/29/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 55 Male 174 lb 1/16/2007 Physician Japan
Primary
Concomitant
Tremor 9/12/2006 59 Male 10/23/2006 United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/26/2006 55 Male 174 lb 1/23/2007 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/13/2006 87 Female 82 lb 1/19/2007 Physician Japan
Primary
Concomitant
Wheezing 9/1/2006 49 Male 11/21/2006 United States
Primary
Concomitant
Pleural Effusion Other Serious 12/27/2005 75 Female 142 lb 2/15/2007 Physician Canada
Primary
Concomitant
Pleural Effusion Other Serious 11/20/2006 76 Female 142 lb 2/15/2007 Physician Canada
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/19/2007 Female 169 lb 2/22/2007 United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 12/27/2005 75 Female 151 lb 2/27/2007 Physician Canada
Primary
Concomitant
Pleural Effusion Other Serious 11/20/2006 76 Female 151 lb 2/27/2007 Physician Canada
Primary
Concomitant
Cerebrovascular Accident Hospitalization 2/19/2007 Female 169 lb 3/5/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected 67 Female 3/7/2007 Consumer United States
Primary
Concomitant
Nocturia 8/1/2006 80 Male 12/5/2006 United States
Primary
Concomitant
Arterial Bypass Operation Other Serious 2/28/2007 Male 170 lb 3/16/2007 Consumer United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 6/1/2004 43 Male 3/15/2007 Physician United States
Primary
Concomitant
Hepatitis B Other Serious 10/4/2006 Female 4/27/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 2/19/2007 Female 169 lb 4/25/2007 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 2/19/2007 Female 169 lb 5/2/2007 Physician United States
Primary
Secondary
Concomitant
Carotid Artery Bypass Other Serious 2/28/2007 Male 170 lb 5/4/2007 Physician United States
Primary
Concomitant
Angioedema Hospitalization 4/15/2007 75 Male 180 lb 4/27/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Wheezing 9/1/2006 49 Male 2/22/2007 United States
Primary
Concomitant
Hyperkalaemia Hospitalization 2/9/2007 79 Female 5/25/2007 United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/6/2007 81 Female 7/6/2007 Physician Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 6/21/2007 Female 110 lb 7/13/2007 Consumer Switzerland
Primary
Concomitant
Haematemesis Hospitalization 7/2/2007 84 Female 93 lb 7/18/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 6/21/2007 Female 110 lb 7/24/2007 Consumer Switzerland
Primary
Concomitant
Faeces Discoloured Hospitalization 82 Male 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Percentage Increased Hospitalization 4/6/2007 81 Female 8/9/2007 Japan
Primary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 4/11/2007 Female 152 lb 8/16/2007 Japan
Primary
Secondary
Concomitant
Faeces Discoloured Hospitalization 82 Male 8/21/2007 Physician Japan
Primary
Secondary
Concomitant
Faeces Discoloured Other Serious 82 Male 8/30/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 8/1/2004 Female 9/4/2007 United States
Primary
Secondary
Concomitant
Dyspnoea 5/3/2007 Male 9/5/2007 Consumer United States
Primary
Concomitant
Faeces Discoloured Other Serious 82 Male 9/17/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 6/19/2007 66 Female 9/20/2007 Other Health Professional Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 6/21/2007 Female 110 lb 9/26/2007 Consumer Switzerland
Primary
Concomitant
Hyperkalaemia Life Threatening 2/9/2007 79 Female 10/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Mitral Valve Incompetence Life Threatening 6/19/2007 66 Female 10/11/2007 Japan
Primary
Concomitant
Myalgia 6/14/2007 83 Female 134 lb 10/3/2007 Consumer United States
Primary
Concomitant
Rash Generalised Hospitalization 9/20/2007 Female 10/26/2007 Physician Japan
Primary
Concomitant
Mitral Valve Incompetence Life Threatening 6/19/2007 66 Female 10/29/2007 Japan
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 106 lb 11/2/2007 Consumer United States
Primary
Concomitant
Haematemesis Hospitalization 7/2/2007 84 Female 93 lb 11/5/2007 Physician Japan
Primary
Secondary
Concomitant
Rash Generalised Disability 9/21/2007 Female 11/9/2007 Physician Japan
Primary
Concomitant
Thrombosis Hospitalization 1/1/2006 59 Female 11/13/2007 Consumer United States
Primary
Concomitant
Weight Increased Life Threatening 6/19/2007 66 Female 11/13/2007 Japan
Primary
Concomitant
Upper Respiratory Tract Infection Life Threatening 11/26/2006 71 Female 104 lb 12/28/2007 Other Health Professional Japan
Primary
Concomitant
Interacting
Muscular Weakness Life Threatening 11/26/2006 71 Female 104 lb 12/28/2007 Other Health Professional Japan
Primary
Concomitant
Interacting
Upper Respiratory Tract Infection Life Threatening 11/26/2006 71 Female 104 lb 12/28/2007 Other Health Professional Japan
Primary
Concomitant
Interacting
Muscular Weakness Life Threatening 11/26/2006 71 Female 104 lb 12/28/2007 Other Health Professional Japan
Primary
Concomitant
Interacting
Weight Decreased Other Serious 1/1/2005 Female 154 lb 2/6/2008 Consumer United States
Primary
Concomitant
Malaise 3/4/2008 32 Male 143 lb 3/21/2008 Other Health Professional United States
Primary
Concomitant
Urine Output Decreased Life Threatening 3/1/2008 78 Female 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/1/2008 82 Female 3/20/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 2/2/2008 82 Female 3/26/2008 Physician Japan
Primary
Concomitant
Chest Pain Hospitalization 3/28/2008 Female 280 lb 4/3/2008 Consumer United States
Primary
Concomitant
Malaise 3/4/2008 32 Male 143 lb 4/10/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 263 lb 4/16/2008 Physician United States
Primary
Concomitant
Hypothyroidism Other Serious 1/10/2008 Female 77 lb 4/22/2008 Physician Japan
Primary
Concomitant
Vision Blurred 12/1/2007 74 Female 154 lb 3/14/2008 Consumer United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 3/28/2008 Female 280 lb 5/5/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 263 lb 5/7/2008 Physician United States
Primary
Concomitant
Urticaria Other Serious 5/2/2008 69 Female 5/23/2008 Physician Switzerland
Primary
Concomitant
Hypothyroidism Other Serious 1/10/2008 Female 77 lb 5/20/2008 Physician Japan
Primary
Concomitant
Weight Decreased 9/1/2005 Female 163 lb 4/10/2008 Consumer United States
Primary
Concomitant
Cerebral Infarction Hospitalization 2/1/2008 82 Female 7/7/2008 Japan
Primary
Concomitant
Somnolence Other Serious 6/28/2008 Male 7/11/2008 Canada
Primary
Concomitant
Urticaria Other Serious 5/2/2008 69 Female 7/16/2008 Physician Switzerland
Primary
Concomitant
Duodenal Perforation Hospitalization 6/13/2008 82 Female 7/9/2008 Physician Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 6/28/2008 Male 7/22/2008 Pharmacist Canada
Primary
Concomitant
Vascular Graft Hospitalization 7/14/2008 75 Female 7/28/2008 Consumer United States
Primary
Concomitant
Oedema Mouth 1/1/2007 82 Female 141 lb 7/29/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious Female 8/7/2008 Physician United States
Primary
Concomitant
Reflux Oesophagitis Life Threatening 2/1/2008 72 Female 8/13/2008 Japan
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2008 Male 200 lb 8/25/2008 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2007 Female 244 lb 9/3/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious Female 9/19/2008 Other Health Professional United States
Primary
Concomitant
Mental Disorder Hospitalization 6/13/2008 82 Female 9/18/2008 Physician Japan
Primary
Secondary
Concomitant
Peripheral Coldness 80 Female 180 lb 10/7/2008 United States
Primary
Concomitant
Urinary Retention Other Serious 8/21/2008 81 Male 112 lb 10/3/2008 Physician Japan
Primary
Concomitant
Prostate Cancer Recurrent Other Serious 11/3/2008 Male 200 lb 12/2/2008 United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2008 Female 12/2/2008 Consumer United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 10/2/2006 Female 190 lb 12/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Pressure Inadequately Controlled 10/28/2008 Male 12/3/2008 Pharmacist
Primary
Concomitant
Venous Thrombosis Other Serious 6/1/2008 Female 119 lb 12/12/2008 Physician Japan
Primary
Concomitant
Basal Cell Carcinoma 1/1/2004 Female 124 lb 12/12/2008 Consumer United States
Primary
Concomitant
Venous Thrombosis Other Serious 6/1/2008 Female 119 lb 12/24/2008 Physician Japan
Primary
Concomitant
Oral Surgery Other Serious 1/1/2008 Male 210 lb 12/29/2008 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2008 Female 12/29/2008 Pharmacist United States
Primary
Concomitant
Blood Pressure Inadequately Controlled 10/28/2008 Male 1/12/2009 Pharmacist
Primary
Concomitant
Anaemia Hospitalization 5/15/2008 1/15/2009 Other Health Professional Germany
Primary
Concomitant
Prostatic Disorder Other Serious 1/1/2008 Male 210 lb 1/15/2009 United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 12/1/2008 Male 1/20/2009 United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2008 Female 2/2/2009 Pharmacist United States
Primary
Concomitant
Left Ventricular Hypertrophy Hospitalization 1/1/2002 90 Female 2/3/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interacting
Renal Failure Acute Hospitalization 12/1/2008 Male 180 lb 2/20/2009 United States
Primary
Concomitant
Stent Placement Other Serious Male 185 lb 3/5/2009 Consumer United States
Primary
Concomitant
Urinary Retention Other Serious 8/15/2008 81 Male 115 lb 3/5/2009 Physician Japan
Primary
Concomitant
Prostatic Disorder Other Serious 1/1/2008 Male 209 lb 3/17/2009 United States
Primary
Concomitant
Open Fracture Hospitalization 2/19/2009 48 Male 340 lb 3/18/2009 United States
Primary
Concomitant
Prostatic Disorder Other Serious 1/1/2008 Male 209 lb 3/30/2009 United States
Primary
Concomitant
Vomiting Hospitalization 3/1/2009 Female 174 lb 4/2/2009 Other Health Professional Canada
Primary
Concomitant
Visual Impairment Other Serious 1/1/2008 Female 162 lb 4/7/2009 Consumer United States
Primary
Secondary
Concomitant
Procedural Pain Other Serious 3/1/2009 61 Male 154 lb 4/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/1/2009 Female 174 lb 4/24/2009 Other Health Professional Canada
Primary
Concomitant
Sleep Disorder Other Serious 1/30/2009 Male 192 lb 4/24/2009 United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 4/15/2009 75 Female 88 lb 4/27/2009 Other Health Professional United States
Primary
Concomitant
Pyrexia 1/1/2008 Male 5/4/2009 Consumer United States
Primary
Concomitant
Anaemia Hospitalization 5/15/2008 5/7/2009 Other Health Professional Germany
Primary
Concomitant
Therapeutic Response Decreased 9/27/2007 83 Male 160 lb 5/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 1/16/2009 Female 178 lb 5/18/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/23/2008 Male 5/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Orthopnoea Other Serious 4/1/2009 Female 5/20/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 1/16/2009 Female 178 lb 5/27/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 5/2/2009 81 Male 6/4/2009 Physician United States
Primary
Secondary
Concomitant

Drug Data