Norepinephrine combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/8/2005 74 236 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 15 Male 2/24/2006 Other Health Professional Netherlands
Primary
Concomitant
Loss Of Consciousness Other Serious 51 Male 2/28/2006
Primary
Secondary
Concomitant
Ventricular Arrhythmia Hospitalization 24 Male 2/28/2006 Other Health Professional Netherlands
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Male 3/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Urine Colour Abnormal Life Threatening 16 Female 73 lb 3/6/2006 Other Health Professional Germany
Primary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/8/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 15 Male 3/10/2006 Other Health Professional Netherlands
Primary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/10/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Female 3/27/2006 United Kingdom
Primary
Secondary
Concomitant
Propofol Infusion Syndrome Required Intervention 15 Male 3/30/2006 Physician Canada
Primary
Concomitant
Pulmonary Embolism Life Threatening 2/21/2006 74 Female 168 lb 4/12/2006 Physician Israel
Primary
Concomitant
Propofol Infusion Syndrome Required Intervention 16 Female 73 lb 4/21/2006 Physician Germany
Primary
Concomitant
Ventricular Dysfunction Other Serious 21 Male 5/17/2006 Other Health Professional United States
Primary
Secondary
Pulse Absent Other Serious 2/6/2005 63 Male 5/22/2006 Pharmacist United States
Primary
Concomitant
Rash Macular 1/23/2007 Male 229 lb 7/12/2007 Other Health Professional Australia
Primary
Concomitant
Sinus Tachycardia Life Threatening 8/18/2006 63 Male 7/9/2007 Japan
Primary
Secondary
Concomitant
Haemorrhage Required Intervention 7/8/2007 59 Male 209 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Sinus Tachycardia Life Threatening 8/18/2006 63 Male 7/26/2007 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/11/2004 52 Male 7/31/2007 Canada
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 1/30/2007 Male 225 lb 2/2/2007 United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 70 Female 9/5/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 9/5/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Troponin I Increased Death 11/1/2007 52 Female 143 lb 2/14/2008 Physician Germany
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 11/1/2006 21 Female 88 lb 2/14/2008 Physician Germany
Primary
Secondary
Concomitant
Interacting
Troponin I Increased Hospitalization 11/1/2006 21 Female 88 lb 2/14/2008 Physician Germany
Primary
Secondary
Concomitant
Interacting
Thermal Burn Other Serious 10/31/2003 Male 2/22/2008 Physician Germany
Primary
Secondary
Thermal Burn Other Serious 10/31/2003 Male 3/12/2008 Physician Germany
Primary
Secondary
Heparin-induced Thrombocytopenia Hospitalization 3/4/2008 66 Female 271 lb 4/10/2008 Pharmacist United States
Primary
Concomitant
Haemorrhage Other Serious 6/28/2004 64 Male 4/29/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 11/1/2006 21 Female 88 lb 5/17/2008 Physician Germany
Primary
Secondary
Concomitant
Interacting
Troponin I Increased Death 11/1/2007 52 Female 143 lb 5/17/2008 Physician Germany
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 4/6/2007 61 Male 4/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Death 33 Female 7/3/2008 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Death 54 Male 101 lb 7/21/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 8/23/2008 89 Male 132 lb 9/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Lung Injury Other Serious 38 Female 12/3/2008
Primary
Concomitant
Shock Other Serious 11/23/2008 76 Male 185 lb 1/9/2009 Other Health Professional Canada
Primary
Concomitant
Propofol Infusion Syndrome Life Threatening 2/2/2009 52 Male 269 lb 2/16/2009 Pharmacist United States
Primary
Concomitant
Cardio-respiratory Arrest Life Threatening 1/15/2009 63 Female 3/9/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 2/1/2009 49 Male 3/11/2009 Physician United States
Primary
Concomitant
Ototoxicity Other Serious 51 Female 315 lb 3/16/2009
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 37 Female 108 lb 3/30/2009 Other Health Professional France
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 2/17/2009 34 Male 300 lb 2/18/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 11/27/2007 58 Female 123 lb 2/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 2/4/2010 Consumer Canada
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 2/18/2010 Lawyer United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 71 Male 187 lb 2/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Pyrexia Other Serious 11/1/2007 62 Female 143 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 71 Male 3/3/2010 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 36 Male 3/15/2010 Lawyer United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 37 Female 108 lb 3/8/2010 Physician France
Primary
Concomitant
Thrombocytopenia Life Threatening 1/12/2010 72 Male 203 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 71 Male 3/24/2010 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 24 Female 4/29/2010
Primary
Secondary
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 5/3/2010 Other Health Professional United States
Primary
Concomitant
Hypotension Death Female 5/21/2010 Physician United States
Primary
Concomitant
Pyrexia Other Serious 6/1/2006 62 Female 143 lb 5/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 36 Male 123 lb 6/11/2010 Lawyer United States
Primary
Concomitant
Hypertension Other Serious 1/1/2008 65 Male 258 lb 6/15/2010 Lawyer United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 12/1/2009 55 Female 110 lb 6/23/2010 Physician Netherlands
Primary
Concomitant
Wound Secretion Other Serious 1/1/2008 68 Male 6/25/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 7/1/2010 Consumer Canada
Primary
Secondary
Concomitant
Hypotension Other Serious 1/3/2008 76 Male 7/7/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 1/23/2008 78 Female 7/13/2010 Lawyer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 12/1/2007 50 Male 309 lb 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Vascular Graft Occlusion Other Serious 2/1/2008 53 Male 203 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 42 Female 183 lb 10/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 12/1/2007 50 Male 309 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 42 Female 183 lb 10/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 36 Male 123 lb 10/25/2010 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 65 Male 207 lb 10/25/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2008 44 Male 452 lb 11/9/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/1/2007 36 Male 123 lb 11/18/2010 Lawyer United States
Primary
Concomitant
Psychomotor Hyperactivity Other Serious 9/12/2010 75 Male 11/19/2010 Other Health Professional Italy
Primary
Concomitant
Tachycardia Other Serious 1/1/2008 78 Female 205 lb 11/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 11/22/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 75 Male 157 lb 11/29/2010 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 12/1/2007 50 Male 309 lb 12/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Uterine Cancer Hospitalization Female 12/2/2010 Physician Netherlands
Primary
Concomitant
Intestinal Ischaemia Death 5/23/2010 68 Male 12/10/2010 Other Health Professional Japan
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 50 Male 262 lb 12/20/2010 Other Health Professional United States
Primary
Concomitant
Pneumatosis Intestinalis Other Serious 10/25/2010 72 Male 159 lb 2/22/2011 Other Health Professional France
Primary
Concomitant
Coagulation Time Prolonged Death 5/23/2010 68 Male 2/28/2011 Other Health Professional Japan
Primary
Concomitant
Pneumatosis Intestinalis Other Serious 10/25/2010 72 Male 159 lb 3/2/2011 Other Health Professional France
Primary
Concomitant
Sepsis Life Threatening 10/22/2010 72 Male 159 lb 3/11/2011 Other Health Professional France
Primary
Concomitant
Peritonitis Hospitalization 10/22/2010 72 Male 154 lb 3/30/2011 Other Health Professional France
Primary
Concomitant
Medication Error Other Serious 10/22/2010 72 Male 154 lb 4/4/2011 Other Health Professional France
Primary
Concomitant
Pseudomembranous Colitis Death 9/18/2010 44 Male 4/13/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Life Threatening 6/7/2012 65 Male 231 lb 6/14/2012 Pharmacist United States
Primary
Secondary
Concomitant
Optic Ischaemic Neuropathy Disability 36 Male 130 lb 7/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Unevaluable Event Other Serious Male 134 lb 7/19/2012 Other Health Professional United States
Primary
Concomitant
Accidental Overdose Hospitalization 17 Male 7/23/2012 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious Male 134 lb 7/23/2012 Other Health Professional United States
Primary
Concomitant
Multi-organ Failure Life Threatening 7/19/2012 49 Male 236 lb 8/10/2012 Physician Canada
Primary
Concomitant
Circulatory Collapse Death 23 8/14/2012 Other Health Professional Netherlands
Primary
Concomitant
Psychomotor Hyperactivity Other Serious 9/12/2010 75 Male 8/28/2012 Other Health Professional It
Primary
Concomitant
Multi-organ Failure Life Threatening 7/19/2012 50 Male 236 lb 11/9/2012 Physician Ca
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 2012 76 Female 10/6/2012 Consumer Si
Primary
Concomitant
Peritonsillar Abscess Hospitalization 8/11/2012 72 Female 143 lb 11/15/2013 Physician Us
Primary
Secondary
Concomitant
Stress Life Threatening 12/31/2010 33 Female 150 lb 9/24/2012 Consumer Us
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 8/29/2012 59 Female 205 lb 10/1/2012 Other Health Professional Us
Primary
Concomitant
Renal Failure Chronic Other Serious 45 Female 143 lb 10/1/2012 Other Health Professional Us
Primary
Concomitant
Shock Hospitalization 10/4/2012 54 Male 12/10/2012 Consumer Us
Primary
Concomitant
Sepsis Death 10/12/2012 57 Female 11/7/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Renal Failure Death Male 12/27/2012 Other Health Professional Nl
Primary
Secondary
Sepsis Life Threatening 1/2/2013 57 Male 167 lb 1/14/2013 Physician Us
Primary
Concomitant
Ventricular Fibrillation Hospitalization 11/16/2012 46 Female 1/23/2013 Other Health Professional Fr
Primary
Concomitant
Respiratory Failure Other Serious 12/21/2012 53 Male 2/26/2013 Consumer Us
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 10/28/2012 76 Male 126 lb 12/11/2013 Consumer Us
Primary
Secondary
Concomitant
Hypoxic-ischaemic Encephalopathy Life Threatening 10/2/2012 41 Male 11/14/2013 Physician At
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 4/25/2013 67 Female 270 lb 5/8/2013 Pharmacist Us
Primary
Secondary
Concomitant
Hyperthermia Malignant Other Serious 4/24/2013 84 Female 88 lb 10/1/2013 Consumer Jp
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 1/25/2013 51 Male 189 lb 6/25/2013 Physician Us
Primary
Secondary
Concomitant
Tachycardia Other Serious 22 Female 7/10/2013 Other Health Professional Cn
Primary
Secondary
Concomitant
Premature Baby Other Serious NotSpecified 7/11/2013 Other Health Professional Cn
Primary
Secondary
Hypoxia Hospitalization 5/2013 72 Male 8/20/2013 No
Primary
Secondary
Concomitant
Carcinoid Crisis Hospitalization 68 Female 9/7/2013 Other Health Professional Gr
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 9/28/2012 63 Male 175 lb Pharmacist Us
Primary
Concomitant
Weight Decreased Other Serious 60 Female 165 lb 10/11/2013 Us
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 1/13/2012 71 Male 226 lb 6/4/2012 Registered Nurse Us
Primary
Concomitant

Drug Data