Norepinephrine Bitartrate combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Impairment Disability 12/10/2005 80 Male 126 lb 1/12/2006 Physician Japan
Primary
Concomitant
Troponin I Increased Other Serious 11/3/2005 35 Male 170 lb 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Unknown 3/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 51 Female 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulse Absent Other Serious 2/6/2005 63 Male 5/22/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Hospitalization 6/6/2006 Female 151 lb 7/4/2006 Pharmacist United States
Primary
Concomitant
Autoimmune Thrombocytopenia Other Serious 2/27/2002 65 Male 220 lb 7/20/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 8/7/2005 64 Male 7/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Haemorrhage 4/21/2005 87 Male 9/4/2006 Japan
Primary
Concomitant
Prothrombin Time Prolonged 4/21/2005 87 Male 9/28/2006 Japan
Primary
Concomitant
Ventricular Dysfunction Other Serious 21 Male 174 lb 10/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 9/1/2006 54 Male 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2005 77 Male 161 lb 1/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2005 77 Male 161 lb 3/8/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
No Therapeutic Response Required Intervention 26 Male 179 lb 5/7/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Neutropenia Required Intervention 29 Female 165 lb 5/7/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Death 6/6/2007 65 Male 187 lb 6/15/2007 Pharmacist Canada
Primary
Concomitant
Post Procedural Complication Hospitalization Male 116 lb 7/11/2007 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Required Intervention 0 Female 12 lb 7/25/2007 Physician United States
Primary
Secondary
Concomitant
Mediastinitis Hospitalization 10/27/2006 Male 116 lb 8/10/2007 Physician Japan
Primary
Concomitant
Venous Thrombosis Other Serious 8/9/2007 8/27/2007 Physician Germany
Primary
Concomitant
Venous Thrombosis Other Serious 8/9/2007 8/30/2007 Physician Germany
Primary
Concomitant
Proteus Infection Life Threatening 8/18/2007 69 Male 9/7/2007 United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 8/9/2007 9/13/2007 Physician Germany
Primary
Concomitant
Leukopenia Life Threatening 8/17/2007 69 Male 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Leukopenia Life Threatening 8/17/2007 69 Male 10/5/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 8/9/2007 11/20/2007 Physician Germany
Primary
Concomitant
Heart Rate Abnormal Required Intervention 58 Female 11/27/2007 Consumer Australia
Primary
Concomitant
Vascular Occlusion 3/19/2006 Male 12/5/2007 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 7/17/2007 22 Female 12/13/2007 Germany
Primary
Concomitant
Drug Physiologic Incompatibility Life Threatening 7/17/2007 22 Female 12/20/2007 Germany
Primary
Concomitant
Loss Of Consciousness Life Threatening 10/29/2007 56 Female 12/6/2007 Germany
Primary
Concomitant
Venous Thrombosis Limb Other Serious 8/9/2007 12/28/2007 Physician Germany
Primary
Concomitant
Drug Physiologic Incompatibility Life Threatening 7/17/2007 22 Female 1/16/2008 Germany
Primary
Concomitant
Multi-organ Failure Hospitalization 8/22/2007 80 Female 194 lb 1/31/2008 Physician Germany
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 9/1/2004 33 Female 2/28/2008 Consumer United States
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 8/22/2007 Female 194 lb 2/28/2008 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/16/2005 Female 3/4/2008 Consumer
Primary
Secondary
Concomitant
Drug Physiologic Incompatibility Life Threatening 7/17/2007 22 Female 3/6/2008 Pharmacist Germany
Primary
Concomitant
Venous Thrombosis Limb Other Serious 8/9/2007 Male 187 lb 3/17/2008 Physician Germany
Primary
Concomitant
Venous Thrombosis Limb Other Serious 8/9/2007 Male 187 lb 3/20/2008 Physician Germany
Primary
Concomitant
Toxic Encephalopathy Hospitalization 49 Female 4/17/2008 Physician Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 24 Female 4/24/2008 Consumer Canada
Primary
Concomitant
Rebound Effect Other Serious 53 Male 4/24/2008 Consumer Canada
Primary
Concomitant
Rebound Effect Other Serious 32 Male 4/24/2008 Consumer Canada
Primary
Concomitant
Shock Death 64 Male 6/19/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Death 33 Female 6/19/2008 Other Health Professional United States
Primary
Concomitant
Venous Thrombosis Limb Other Serious 8/9/2007 Male 187 lb 7/25/2008 Physician Germany
Primary
Concomitant
Troponin Increased Hospitalization 49 Female 9/19/2008 Canada
Primary
Secondary
Venous Thrombosis Limb Other Serious 8/9/2007 Male 187 lb 9/25/2008 Physician Germany
Primary
Concomitant
Pyrexia Hospitalization 8/28/2008 9/16/2008 Pharmacist United States
Primary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 1/1/2009 Male 157 lb 2/4/2009 Other Health Professional Germany
Primary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 1/1/2009 Male 157 lb 2/9/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/22/2009 4/20/2009 Pharmacist United States
Primary
Concomitant
Propofol Infusion Syndrome Other Serious 36 Female 5/26/2009 Pharmacist United States
Primary
Concomitant
Rash Morbilliform Other Serious 36 Female 137 lb 5/20/2009 Physician United States
Primary
Secondary
Concomitant
Device Failure Other Serious 4/6/2007 61 Male 5/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Death 73 Male 8/7/2009 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Anaphylactic Reaction Death 73 Male 225 lb 8/27/2009 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 42 Female 183 lb 9/21/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 65 Male 207 lb 9/21/2009 Physician United States
Primary
Secondary
Concomitant
Diabetic Coma Other Serious 5/6/2007 52 Female 122 lb 9/23/2009 United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Required Intervention 21 Female 128 lb 10/6/2009 Switzerland
Primary
Concomitant
Vomiting Other Serious 7/8/2008 34 Female 1/7/2010 Consumer United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2008 59 Female 2/26/2010 Lawyer United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2008 34 Female 117 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 8/25/2008 72 Male 7/15/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 4/28/2008 74 Male 190 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Vascular Graft Occlusion Other Serious 2/1/2008 53 Male 203 lb 8/12/2010 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1/1/2008 65 Male 258 lb 8/12/2010 Lawyer United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/2008 68 Male 8/20/2010 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 7/1/2010 75 Male 179 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 10/1/2007 75 Male 9/2/2010 Lawyer United States
Primary
Concomitant
Serratia Infection Other Serious 1/1/2008 64 Male 165 lb 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2008 78 Female 205 lb 9/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 9/1/2007 71 Male 9/27/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/1/2008 34 Female 117 lb 11/29/2010 Consumer United States
Primary
Secondary
Concomitant
Vascular Graft Occlusion Other Serious 2/1/2008 53 Male 203 lb 12/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 23 Female 132 lb 12/30/2010 Other Health Professional Israel
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Chills Life Threatening 1/1/2008 70 Male 256 lb 1/31/2011 Lawyer United States
Primary
Secondary
Concomitant
Asthenia Other Serious 1/1/2008 74 Male 190 lb 2/3/2011 Lawyer United States
Primary
Concomitant
Headache Other Serious 1/1/2008 65 Male 258 lb 2/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 1/12/2008 59 Male 2/23/2011 Physician United States
Primary
Secondary
Concomitant
Pain Death 12/9/2004 62 Female 342 lb 2/28/2011 Consumer United States
Primary
Concomitant
Anhedonia Other Serious 12/9/2004 62 Female 342 lb 2/28/2011 Consumer United States
Primary
Concomitant
Respiratory Failure Death 12/1/2007 50 Male 309 lb 3/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Injury Other Serious 9/5/2005 51 Male 295 lb 3/9/2011 Lawyer United States
Primary
Concomitant
Arrhythmia Other Serious 9/5/2005 51 Male 295 lb 3/9/2011 Consumer United States
Primary
Concomitant
Multi-organ Failure Death 12/17/2002 79 Female 244 lb 3/18/2011 Lawyer United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 1/1/2008 59 Male 3/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 1/16/2004 75 Female 165 lb 3/22/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 7/12/2006 64 Female 190 lb 3/29/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 7/12/2006 64 Female 190 lb 3/29/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 11/4/2006 74 Male 165 lb 3/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypovolaemic Shock Death 10/1/2007 75 Male 157 lb 3/31/2011 Lawyer United States
Primary
Secondary
Concomitant
Injury Other Serious 1/31/2007 72 Male 205 lb 4/4/2011 Consumer United States
Primary
Concomitant
Fear Other Serious 1/31/2007 72 Male 205 lb 4/4/2011 Other Health Professional United States
Primary
Concomitant
Anaemia Other Serious 2/10/2011 53 Male 4/6/2011 Other Health Professional Japan
Primary
Concomitant
Jaundice Hospitalization 9/12/2010 74 Male 4/8/2011 Other Health Professional Italy
Primary
Concomitant
Depression Other Serious 1/1/2003 44 Male 258 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Injury Death 1/1/2003 44 Male 258 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Acute Hepatic Failure Death 23 Female 132 lb 4/11/2011 Physician United States
Primary
Concomitant
Pneumonia Other Serious 23 Female 132 lb 4/12/2011 Physician United States
Primary
Concomitant
Anhedonia Death Female 247 lb 4/13/2011 Consumer United States
Primary
Concomitant
Anhedonia Death Female 247 lb 4/13/2011 Lawyer United States
Primary
Concomitant
Death Death 2/19/2007 80 Male 180 lb 4/14/2011 Other Health Professional United States
Primary
Concomitant
Off Label Use Death 68 Male 4/15/2011 Consumer Canada
Primary
Concomitant
Emotional Distress Hospitalization 6/22/2005 56 Male 251 lb 4/15/2011 Lawyer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 4/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 12/1/2010 71 Female 127 lb 4/19/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Stress Other Serious 10/8/2001 22 Male 209 lb 4/19/2011 Lawyer United States
Primary
Concomitant
Depression Other Serious 6/22/2005 56 Male 200 lb 4/19/2011 Consumer United States
Primary
Concomitant
Atrial Fibrillation Other Serious 2/10/2011 53 Male 4/19/2011 Other Health Professional Japan
Primary
Concomitant
Anxiety Death 12/1/2006 67 Male 161 lb 4/20/2011 Lawyer United States
Primary
Concomitant
Shock Other Serious 1/1/2011 72 Female 4/26/2011 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 1/31/2007 72 Male 205 lb 4/26/2011 Other Health Professional United States
Primary
Concomitant
Atrial Fibrillation Other Serious 12/1/2010 71 Female 127 lb 4/27/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Anhedonia Death Female 247 lb 4/29/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Other Serious 42 Female 137 lb 5/6/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Other Serious 8/1/2005 74 Female 111 lb 5/12/2011 Other Health Professional United States
Primary
Concomitant
Hypoxia Other Serious 1/6/2011 59 Female 130 lb 4/13/2011 Pharmacist United States
Primary
Concomitant
Injury Other Serious 29 Male 190 lb 5/17/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 48 Female 118 lb 5/18/2011 Other Health Professional United States
Primary
Concomitant
Emotional Distress Other Serious 3/11/2001 63 Male 190 lb 5/18/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Death 2/27/2005 76 Female 160 lb 5/19/2011 Other Health Professional United States
Primary
Concomitant
Cerebral Infarction Hospitalization 8/2/2009 62 Male 165 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Convulsion Other Serious 6/15/2010 5/23/2011 Other Health Professional Australia
Primary
Secondary
Renal Tubular Necrosis Hospitalization 6/22/2005 56 Male 200 lb 5/21/2011 Lawyer United States
Primary
Concomitant
Haematemesis Death 11/10/2010 75 Male 148 lb 5/25/2011 Physician France
Primary
Concomitant
Anxiety Death 3/27/2001 76 Male 203 lb 5/25/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/25/2007 59 Female 166 lb 5/25/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/2/2005 77 Male 5/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2005 77 Male 5/27/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2005 77 Male 161 lb 5/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2005 77 Male 5/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization Female 5/31/2011 Pharmacist United Kingdom
Primary
Secondary
Convulsion Other Serious 6/15/2010 75 Male 5/31/2011 Other Health Professional Australia
Primary
Secondary
Oedema Hospitalization Female 6/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Liver Function Test Abnormal Hospitalization 1/2/2005 77 Male 6/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Phosphorus Decreased Hospitalization Female 5/18/2011 Pharmacist United Kingdom
Primary
Secondary
Fear Other Serious 12/30/2002 55 Male 280 lb 6/4/2011 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 6/15/2010 75 Male 5/26/2011 Other Health Professional Australia
Primary
Secondary

Drug Data