Nitrous Oxide combined with Sevoflurane

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vision Blurred Other Serious 15 Male 7/18/2007 Australia
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 9/24/2006 62 Female 7/27/2007 Japan
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 15 Male 152 lb 7/27/2007
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 9/28/2006 50 Female 7/27/2007 Japan
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 49 Male 7/30/2007 Physician Japan
Primary
Concomitant
Respiratory Depression Other Serious 49 Male 7/30/2007 Physician Japan
Primary
Concomitant
Supraventricular Tachycardia Other Serious 76 Male 8/17/2007 Other Health Professional Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 1 Female 13 lb 8/27/2007 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 0 Male 13 lb 8/28/2007 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 0 Female 10 lb 8/28/2007 United States
Primary
Secondary
Ventricular Tachycardia Other Serious 0 Female 12 lb 8/28/2007 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 65 Male 9/17/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypotension Other Serious 55 Male 130 lb 9/21/2007 Japan
Primary
Secondary
Concomitant
Miosis Hospitalization 9/27/2007 Physician United States
Primary
Secondary
Shock Other Serious 67 Male 9/28/2007 Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 0 Female 12 lb 9/19/2007 Other Health Professional United States
Primary
Secondary
Venous Haemorrhage Other Serious 67 Male 10/5/2007 Japan
Primary
Concomitant
Multi-organ Failure Life Threatening 3/14/2007 Male 146 lb 10/23/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 75 Male 10/29/2007 Physician Japan
Primary
Concomitant
Delayed Recovery From Anaesthesia Hospitalization 65 Female 11/2/2007 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 13 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 4/23/2004 30 Male 11/1/2007 Japan
Primary
Secondary
Concomitant
Shock Disability 4/23/2004 27 Male 11/7/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1 Female 11/7/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 11 Male 90 lb 11/14/2007 Japan
Primary
Concomitant
Ventricular Arrhythmia Other Serious 13 Female 121 lb 11/14/2007
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 4/23/2004 27 Male 11/14/2007 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 4/23/2004 27 Male 11/14/2007 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 4/23/2004 27 Male 11/14/2007 United States
Primary
Secondary
Concomitant
Strabismus Other Serious 11/15/2007 Physician Spain
Primary
Concomitant
Strabismus Other Serious 11/15/2007 Physician Spain
Primary
Concomitant
Strabismus Other Serious 11/15/2007 Physician Spain
Primary
Concomitant
Strabismus Other Serious 11/15/2007 Physician Spain
Primary
Concomitant
Strabismus Other Serious 11/15/2007 Physician Spain
Primary
Concomitant
Strabismus Other Serious 11/15/2007 Physician Spain
Primary
Concomitant
Strabismus Other Serious 11/15/2007 Physician Spain
Primary
Concomitant
Strabismus Other Serious 11/16/2007 Physician Spain
Primary
Concomitant
Delayed Recovery From Anaesthesia Life Threatening 65 Female 106 lb 11/16/2007 Japan
Primary
Concomitant
Strabismus Other Serious 11/21/2007 Physician Spain
Primary
Concomitant
Hypotension Other Serious 5/16/2007 55 Male 130 lb 11/27/2007 United States
Primary
Secondary
Concomitant
Iga Nephropathy Other Serious 5/16/2007 Male 130 lb 11/30/2007 Japan
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 66 Male 12/20/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Overdose Hospitalization 12/4/2007 4 Male 1/9/2008 Physician Finland
Primary
Concomitant
Somnolence Life Threatening 12/19/2007 38 Female 159 lb 1/14/2008 United States
Primary
Secondary
Concomitant
Hyperthermia Malignant Other Serious 37 Female 1/16/2008 Other Health Professional Japan
Primary
Concomitant
Pco2 Decreased Other Serious 76 Female 1/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulse Absent Other Serious 12/4/2007 4 Male 40 lb 1/23/2008 Physician Finland
Primary
Concomitant
Acute Myocardial Infarction Other Serious 67 Male 1/25/2008 Japan
Primary
Concomitant
Acute Myocardial Infarction Other Serious 67 Male 146 lb 2/14/2008 Japan
Primary
Concomitant
Unresponsive To Stimuli Required Intervention 2 Male 30 lb 2/11/2008 United States
Primary
Concomitant
Procedural Complication Other Serious 62 Male 112 lb 2/20/2008 Japan
Primary
Concomitant
Renal Impairment Other Serious 11 Female 66 lb 2/27/2008 Turkey
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11 Female 66 lb 2/29/2008 Turkey
Primary
Secondary
Concomitant
Pco2 Decreased Other Serious 2/10/1999 76 Female 3/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 7/22/2005 65 Male 176 lb 3/1/2008 United Kingdom
Primary
Concomitant
Procedural Complication Death 76 Female 3/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Haematocrit Decreased Hospitalization 7/20/2007 71 Male 5/20/2008 Other Health Professional United States
Primary
Concomitant
Migraine With Aura Hospitalization 15 Male 152 lb 6/6/2008 Australia
Primary
Secondary
Concomitant
Ventricular Arrhythmia Life Threatening 13 Female 121 lb 6/18/2008
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 53 Female 7/16/2008 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 53 Female 7/18/2008 Consumer Japan
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 53 Female 7/21/2008 Japan
Primary
Secondary
Rhabdomyolysis Other Serious 45 Male 7/23/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Death 9/16/2005 Female 121 lb 7/23/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Death 53 Female 7/28/2008 Consumer Japan
Primary
Secondary
Drug Toxicity Other Serious 32 Male 148 lb 7/28/2008 Other Health Professional Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 9/16/2005 53 Female 7/30/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Swelling Other Serious 45 Male 140 lb 7/30/2008 Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 53 Female 7/31/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Death 9/16/2005 Female 126 lb 8/8/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 9/16/2005 53 Female 8/11/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 53 Female 8/13/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 9/16/2005 53 Female 8/14/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 31 Female 8/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 8/12/2008 Female 20 lb 9/3/2008 Other Health Professional Japan
Primary
Concomitant
Grand Mal Convulsion Other Serious 4 Female 9/11/2008 Japan
Primary
Concomitant
Drug Ineffective Other Serious 31 Female 9/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diplegia Disability 88 Female 141 lb 9/15/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 9/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 6/27/2008 8 Male 35 lb 8/8/2008 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 30 Female 159 lb 9/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 37 Male 134 lb 10/17/2008 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 37 Male 134 lb 10/29/2008 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/17/2008 Male 134 lb 11/3/2008 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/17/2008 Male 134 lb 11/20/2008 Japan
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 11/6/2008 70 Female 11/25/2008 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 45 Female 141 lb 12/2/2008 Consumer Canada
Primary
Concomitant
Unresponsive To Stimuli Required Intervention 4 Male 37 lb 11/26/2008 Canada
Primary
Concomitant
Angle Closure Glaucoma Other Serious 59 Male 12/10/2008 Other Health Professional Japan
Primary
Concomitant
Tachypnoea Hospitalization 2 Male 20 lb 11/24/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 11/6/2008 70 Female 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 3/12/2008 Male 137 lb 12/16/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/8/2007 Female 12/16/2008 Physician Japan
Primary
Concomitant
Bronchospasm Other Serious 1 Female 20 lb 12/16/2008
Primary
Secondary
Concomitant
Angle Closure Glaucoma Other Serious 59 Male 12/18/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 7 Male 12/23/2008 Japan
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 7 Male 12/23/2008 Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Life Threatening 11/2/2008 0 Male 18 lb 1/5/2009 Physician Japan
Primary
Concomitant
Atrioventricular Block Complete Other Serious 4 Male 35 lb 1/9/2009 Other Health Professional United States
Primary
Concomitant
Tryptase Increased Other Serious 2/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Dystonia Other Serious 1/22/2009 17 Male 2/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dystonia Other Serious 1/22/2009 17 Male 2/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2008 30 Female 2/27/2009 Physician Japan
Primary
Secondary
Concomitant
Dystonia Other Serious 1/22/2009 17 Male 2/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dystonia Other Serious 1/22/2009 17 Male 2/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sensory Disturbance Other Serious 3/14/2007 66 Male 3/3/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2008 30 Female 128 lb 3/18/2009 Physician Japan
Primary
Secondary
Concomitant
Drug Administration Error Other Serious 3/13/2009 69 Female 110 lb 3/31/2009 Physician Canada
Primary
Concomitant
Sensory Disturbance Other Serious 3/14/2007 66 Male 4/7/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3 Female 16 lb 5/4/2009 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 35 Female 4/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 3 Female 16 lb 5/15/2009 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 35 Female 5/18/2009
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 2 Female 35 lb 5/22/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 35 Female 5/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 30 Male 5/28/2009 France
Primary
Concomitant
Interacting
Serotonin Syndrome Other Serious 40 Female 5/29/2009 Consumer Turkey
Primary
Secondary
Concomitant
Long Qt Syndrome Other Serious 35 Female 5/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 40 Female 5/28/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 6/15/2009 United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 40 Female 6/15/2009 Other Health Professional Turkey
Primary
Concomitant
Interacting
Ventricular Tachycardia Life Threatening 35 Female 6/18/2009 United Kingdom
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 7/1/2009 United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/10/2007 Female 16 lb 7/1/2009 Japan
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 7/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 11/8/2001 8 Male 82 lb 7/2/2009 Physician United Kingdom
Primary
Concomitant
Hemiplegia Hospitalization 81 Male 161 lb 7/6/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Serotonin Syndrome Other Serious 1/1/2009 40 Female 7/8/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 7/13/2009 United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 35 Female 7/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/10/2007 Female 16 lb 8/6/2009 Japan
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 32 Female 93 lb 9/4/2009 Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/10/2007 Female 16 lb 9/4/2009 Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 6/27/2008 8 Male 35 lb 8/25/2009 Pharmacist United States
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 9/14/2009 United Kingdom
Primary
Secondary
Concomitant
Swelling Hospitalization 9/14/2009 United Kingdom
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia Other Serious 9/14/2009 United Kingdom
Primary
Secondary
Concomitant
Swelling Hospitalization 9/14/2009 United Kingdom
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Other Serious 9/14/2009 United Kingdom
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Other Serious 9/24/2009 United Kingdom
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Other Serious 9/24/2009 United Kingdom
Primary
Secondary
Concomitant
Swelling Hospitalization 9/24/2009 United Kingdom
Primary
Secondary
Concomitant
Swelling Hospitalization 9/24/2009 United Kingdom
Primary
Secondary
Concomitant
Jaundice Hospitalization 9/1/2009 Female 10/8/2009 Physician Sweden
Primary
Concomitant
Neuromuscular Block Prolonged Hospitalization 10/20/2009
Primary
Secondary
Concomitant
Musculoskeletal Pain Hospitalization 9/14/2009 Female 10/23/2009 Physician Sweden
Primary
Secondary
Concomitant
Musculoskeletal Pain Hospitalization 9/14/2009 Female 12/2/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant

Drug Data