Nifedipine combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vitamin B Complex Deficiency Hospitalization 6/1/2001 64 Female 351 lb 1/23/2006 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 8/14/2001 81 Female 2/2/2006 Other Health Professional France
Primary
Concomitant
Malaise Hospitalization 11/17/2005 59 Female 106 lb 2/8/2006 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 11/29/2005 52 Male 190 lb 1/23/2006 Pharmacist United States
Primary
Concomitant
Sinus Tachycardia Other Serious 1/1/2003 43 Female 181 lb 2/27/2006 Physician United States
Primary
Concomitant
Rash Other Serious 49 Female 237 lb 2/27/2006 Consumer United States
Primary
Concomitant
Odynophagia Hospitalization 1/15/2006 71 Male 3/10/2006 Physician Japan
Primary
Secondary
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/21/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 11/17/2005 59 Female 99 lb 3/14/2006 Physician Japan
Primary
Secondary
Concomitant
Angioneurotic Oedema Hospitalization 1/15/2006 71 Male 3/17/2006 Physician Japan
Primary
Secondary
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/24/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/15/2006 71 Male 4/3/2006 Physician Japan
Primary
Secondary
Ventricular Hypertrophy Hospitalization 5/21/2002 66 Male 216 lb 4/21/2006 Physician United States
Primary
Concomitant
Malaise Hospitalization 11/17/2005 59 Female 99 lb 5/25/2006 Physician Japan
Primary
Secondary
Concomitant
Abdominal Pain Upper Other Serious 1/1/2005 79 Female 220 lb 4/20/2006 United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/22/2005 57 Female 143 lb 6/23/2006 Belgium
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/28/2005 58 Male 7/20/2006 Japan
Primary
Concomitant
Urinary Bladder Haemorrhage Other Serious 3/29/2006 66 Female 8/3/2006 Pharmacist United States
Primary
Concomitant
Respiratory Rate Increased Hospitalization 42 Female 8/28/2006 Italy
Primary
Concomitant
Thirst 63 Male 355 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 42 Female 9/4/2006 Physician Italy
Primary
Concomitant
Hypotension Hospitalization 42 Female 9/18/2006 Physician Italy
Primary
Concomitant
Pneumonitis Other Serious 9/3/2004 57 Male 209 lb 10/3/2006 Physician Greece
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/18/2006 77 Female 213 lb 10/5/2006 United States
Primary
Concomitant
Loss Of Consciousness Other Serious 11/21/2006 51 Male 12/13/2006 Pharmacist Netherlands
Primary
Concomitant
Polymyalgia Rheumatica Required Intervention 7/1/2006 59 Female 159 lb 12/18/2006 Other Health Professional Netherlands
Primary
Concomitant
Vomiting Life Threatening 10/16/2006 54 Female 77 lb 1/5/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/16/2006 54 Female 100 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/16/2006 54 Female 100 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 7/4/2006 49 Female 179 lb 10/20/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 10/18/2006 54 Female 100 lb 1/24/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/12/2005 Male 201 lb 2/6/2007 Physician United States
Primary
Concomitant
Productive Cough Hospitalization 11/20/2006 Male 230 lb 12/22/2006 Pharmacist United States
Primary
Concomitant
Polymyalgia Rheumatica Required Intervention 7/1/2006 59 Female 159 lb 2/21/2007 Other Health Professional Netherlands
Primary
Concomitant
Hypomagnesaemia Hospitalization 1/3/2007 48 Female 2/28/2007 Physician United States
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 3/29/2006 66 Female 3/29/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Hypertension 3/1/2006 65 Female 152 lb 1/23/2007 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/5/2007 65 Male 4/20/2007 Japan
Primary
Concomitant
Rhabdomyolysis Required Intervention 4/28/2006 82 Female 90 lb 4/25/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 15 Male 93 lb 5/14/2007
Primary
Concomitant
Fatigue 11/4/2006 Male 2/22/2007 United States
Primary
Concomitant
Supraventricular Extrasystoles Other Serious 1/5/2007 65 Male 5/21/2007 Japan
Primary
Concomitant
Vomiting Hospitalization 15 Male 92 lb 5/18/2007 United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/3/2004 57 Male 209 lb 6/5/2007 Physician Greece
Primary
Concomitant
Vomiting Hospitalization 15 Male 93 lb 6/15/2007 United States
Primary
Concomitant
Nausea Other Serious 7/16/2007 Female 280 lb 7/27/2007 United States
Primary
Concomitant
Weight Increased 52 Female 227 lb 9/18/2007 Consumer United States
Primary
Concomitant
Asthenia Hospitalization 5/12/2005 Male 201 lb 10/9/2007 Physician United States
Primary
Concomitant
Prothrombin Time Abnormal Other Serious 9/25/2007 Female 11/1/2007 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 10/29/2007 Female 180 lb 11/12/2007 United States
Primary
Concomitant
Death Death 10/31/2007 45 Male 11/21/2007 Other Health Professional United States
Primary
Concomitant
Palpitations 7/21/2007 73 Male 11/16/2007 United States
Primary
Concomitant
Prothrombin Time Abnormal Other Serious 9/25/2007 Female 2/18/2008 Other Health Professional United States
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 4/8/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 4/22/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 5/1/2008 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 6/1/2007 88 Female 5/21/2008 Other Health Professional Sweden
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/6/2008 Male 132 lb 5/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Fall 11/1/2007 Male 210 lb 6/13/2008 United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/6/2008 Male 132 lb 6/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization 6/20/2008 51 Male 6/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Other Serious 2/1/2008 Male 7/3/2008 Physician Japan
Primary
Concomitant
Rash Generalised 1/1/2007 Female 185 lb 7/25/2008 Physician United States
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization 6/20/2008 51 Male 7/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Hospitalization 6/20/2008 51 Male 8/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 12/20/2006 8/8/2008 Consumer United States
Primary
Secondary
Concomitant
Syncope Other Serious 84 Female 8/27/2008 Physician United States
Primary
Secondary
Pulmonary Embolism Other Serious 1 Male 35 lb 9/12/2008 Other Health Professional Canada
Primary
Concomitant
Fall 11/1/2007 Male 210 lb 9/12/2008 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 1 Male 35 lb 9/24/2008 Other Health Professional Canada
Primary
Concomitant
Thrombocytopenia Other Serious 5/1/2007 Male 35 lb 9/24/2008 Other Health Professional Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 1 Male 35 lb 9/29/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 83 Female 130 lb 10/3/2008 Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1 Male 35 lb 10/13/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Impairment Other Serious 83 Female 130 lb 10/14/2008 Japan
Primary
Secondary
Concomitant
Chest Discomfort Hospitalization 11/12/2008 Female 11/26/2008 Consumer United States
Primary
Concomitant
Death Death 9/3/2008 Male 12/19/2008 Physician Netherlands
Primary
Concomitant
Death Death 9/3/2008 Male 172 lb 12/23/2008 Physician Netherlands
Primary
Concomitant
Thrombocytopenia Hospitalization 1 Male 12/22/2008 Other Health Professional Canada
Primary
Concomitant
Drug Interaction Hospitalization 9/29/2008 64 Female 1/5/2009 Consumer Portugal
Primary
Secondary
Concomitant
Vomiting Other Serious 5/1/2007 68 Male 2/20/2009 Lawyer United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 1/1/2009 71 Male 3/4/2009 South Africa
Primary
Concomitant
Pruritus 1/30/2009 Male 184 lb 3/16/2009 Physician United States
Primary
Concomitant
Chest Discomfort Hospitalization 11/12/2008 Female 3/27/2009 Physician United States
Primary
Concomitant
Feeling Jittery 10/1/2008 69 Female 190 lb 3/23/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/24/2009 Female 5/13/2009 Consumer United States
Primary
Concomitant
Weight Decreased Death 68 Male 6/5/2009 United States
Primary
Concomitant
Right Ventricular Failure Life Threatening 4/24/2009 Female 6/24/2009 Physician United States
Primary
Concomitant
Weight Decreased Death 68 Male 7/1/2009 Lawyer United States
Primary
Concomitant
Myositis Other Serious 3/7/2009 Female 124 lb 7/13/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Death 68 Male 7/14/2009 United States
Primary
Concomitant
Weight Decreased Death 68 Male 7/17/2009 United States
Primary
Concomitant
Weight Decreased Death 68 Male 7/21/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 4/5/2005 8/2/2009 Consumer United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 5/4/2006 46 Male 310 lb 8/24/2009 United States
Primary
Concomitant
Weight Decreased Death 68 Male 8/25/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 68 Male 9/25/2009 United States
Primary
Concomitant
Pancreatitis Chronic Other Serious 7/21/2006 65 Male 10/15/2009 United States
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 76 Female 10/19/2009 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 55 Female 11/18/2009 United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 11/18/2009 79 Male 330 lb 11/25/2009 Other Health Professional United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2006 Female 12/4/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 55 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 8/13/2008 54 Female 132 lb 12/9/2009 Other Health Professional Korea, Republic Of
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 4/5/2005 12/17/2009 Consumer United States
Primary
Secondary
Concomitant
Medication Error 10/21/2009 69 Female 184 lb 12/22/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/1/2007 68 Male 12/22/2009 Lawyer United States
Primary
Concomitant
Liver Function Test Abnormal 47 Male 12/22/2009 Physician Germany
Primary
Concomitant
Liver Function Test Abnormal 47 Male 1/6/2010 Physician Germany
Primary
Concomitant
Liver Function Test Abnormal 47 Male 1/8/2010 Physician Germany
Primary
Concomitant
Fatigue Other Serious 12/2/2009 Male 1/20/2010 Other Health Professional Sweden
Primary
Concomitant
Urinary Tract Infection Hospitalization 55 Female 1/13/2010 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Disability 12/10/2009 47 Male 176 lb 2/9/2010 Germany
Primary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 74 Male 2/5/2010 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 74 Male 2/5/2010 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Right Ventricular Failure Life Threatening 4/24/2009 Female 3/4/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/1999 Female 186 lb 3/19/2010 Physician Netherlands
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 4/5/2005 3/24/2010 Consumer United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal 12/10/2009 47 Male 196 lb 4/13/2010 Physician Germany
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 7/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Hospitalization 55 Female 6/25/2010 United States
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 7/13/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 10/14/2002 41 Female 165 lb 7/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Death 6/15/2010 63 Female 7/23/2010 Pharmacist Canada
Primary
Concomitant
Pulmonary Arterial Hypertension Other Serious 8/13/2008 54 Female 132 lb 7/28/2010 Korea, Republic Of
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 7/1/2010 72 Female 128 lb 8/30/2010 Other Health Professional Colombia
Primary
Concomitant
Scleral Haemorrhage Other Serious Female 110 lb 8/24/2010 United States
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/1/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 9/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/28/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Vitamin B12 Decreased Other Serious 1/1/2009 69 Female 10/8/2010 Consumer United States
Primary
Secondary
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 10/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 75 Male 10/19/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/17/2010 77 Male 134 lb 11/1/2010 Physician Japan
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/17/2010 77 Male 134 lb 11/9/2010 Physician Japan
Primary
Concomitant
Underdose Other Serious 1/1/2009 73 Male 254 lb 12/3/2010 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal 12/10/2009 47 Male 196 lb 11/17/2010 Germany
Primary
Concomitant
Thirst Death 12/15/2006 12/6/2010 Physician United States
Primary
Concomitant
Pain In Extremity Death 1/1/2006 12/6/2010 Physician United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 11/18/2009 79 Male 330 lb 3/1/2010 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal 12/10/2009 47 Male 196 lb 12/7/2010 Pharmacist Germany
Primary
Concomitant

Drug Data