Nexium combined with Sorafenib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Life Threatening 12/31/2005 55 Male 155 lb 2/3/2006 United States
Primary
Concomitant
Sepsis Life Threatening 12/31/2005 55 Male 155 lb 2/6/2006 United States
Primary
Concomitant
Fatigue Hospitalization 1/30/2006 49 Male 148 lb 2/9/2006 France
Primary
Concomitant
Weight Decreased Hospitalization 1/30/2006 49 Male 148 lb 2/22/2006 France
Primary
Concomitant
Peptic Ulcer Haemorrhage Life Threatening 5/7/2006 54 Male 143 lb 5/16/2006 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization Male 5/18/2006 Switzerland
Primary
Concomitant
Nausea Life Threatening 5/7/2006 54 Male 143 lb 5/26/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/30/2006 49 Male 148 lb 5/30/2006 France
Primary
Concomitant
Dyspnoea Hospitalization Male 151 lb 6/1/2006 Switzerland
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 12/31/2005 55 Male 155 lb 6/1/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/27/2006 49 Male 121 lb 6/5/2006 Physician France
Primary
Concomitant
Refusal Of Treatment By Patient Life Threatening 3/27/2006 59 Male 156 lb 6/13/2006 France
Primary
Concomitant
Phlebitis Life Threatening 3/27/2006 59 Male 156 lb 6/19/2006 Physician France
Primary
Concomitant
Phlebitis Life Threatening 3/27/2006 59 Male 156 lb 6/23/2006 France
Primary
Concomitant
Vomiting Hospitalization 4/27/2006 49 Male 121 lb 7/5/2006 Physician France
Primary
Concomitant
Sepsis Other Serious 4/1/2006 49 Female 100 lb 7/7/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/27/2006 49 Male 121 lb 7/18/2006 Other Health Professional France
Primary
Concomitant
Pulmonary Hypertension Hospitalization 7/5/2006 54 Male 165 lb 7/25/2006 France
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 7/11/2006 66 Female 179 lb 8/4/2006 Physician Germany
Primary
Concomitant
Phlebitis Life Threatening 3/27/2006 59 Male 157 lb 8/10/2006 Physician France
Primary
Concomitant
Pneumonia Hospitalization 8/16/2006 Female 119 lb 8/28/2006 Physician Germany
Primary
Concomitant
Osteonecrosis Other Serious 6/23/2006 48 Male 9/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/16/2006 Female 119 lb 9/21/2006 Physician Germany
Primary
Concomitant
Respiratory Rate Increased Life Threatening 12/31/2005 56 Male 154 lb 9/25/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 5/7/2006 54 Male 143 lb 10/3/2006 Physician United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 7/5/2006 55 Male 165 lb 10/4/2006 Physician France
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 9/17/2006 56 Male 10/6/2006 Physician Switzerland
Primary
Concomitant
Haemoglobin Decreased Other Serious 5/7/2006 54 Male 143 lb 10/9/2006 Physician United States
Primary
Concomitant
Haemoglobin Decreased Life Threatening 9/13/2005 53 Male 143 lb 10/17/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/9/2006 72 Male 229 lb 10/18/2006 Physician Sweden
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 10/18/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 10/24/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 7/5/2006 55 Male 165 lb 10/25/2006 Physician France
Primary
Concomitant
Vomiting Hospitalization 10/6/2006 59 Male 174 lb 10/30/2006 Physician United States
Primary
Concomitant
Unevaluable Event Hospitalization 6/15/2006 40 Male 11/3/2006 Physician France
Primary
Concomitant
Pulmonary Hypertension Hospitalization 7/5/2006 55 Male 165 lb 11/15/2006 Physician Germany
Primary
Concomitant
Pulmonary Hypertension Hospitalization 7/5/2006 55 Male 165 lb 11/22/2006 Physician Germany
Primary
Concomitant
Fatigue Hospitalization 1/30/2006 50 Male 148 lb 12/4/2006 Physician France
Primary
Concomitant
Vomiting Hospitalization 4/18/2006 75 Male 152 lb 12/18/2006 Physician Switzerland
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 12/21/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 9/1/2005 65 Male 161 lb 12/29/2006 Physician United States
Primary
Concomitant
Duodenal Ulcer Haemorrhage Life Threatening 9/10/2005 53 Male 143 lb 12/29/2006 Physician United States
Primary
Concomitant
Tongue Oedema Other Serious 12/13/2006 51 Male 212 lb 1/3/2007 Physician France
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 1/23/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 9/1/2005 65 Male 161 lb 1/31/2007 Physician United States
Primary
Concomitant
Tongue Oedema Other Serious 12/12/2006 51 Male 212 lb 2/1/2007 Physician France
Primary
Concomitant
Hypophosphataemia Hospitalization 9/17/2006 56 Male 2/20/2007 Physician Switzerland
Primary
Concomitant
Tongue Oedema Other Serious 12/12/2006 51 Male 212 lb 3/1/2007 Physician France
Primary
Concomitant
Dyspnoea Hospitalization 4/18/2006 75 Male 152 lb 3/12/2007 Physician Switzerland
Primary
Concomitant
General Physical Health Deterioration Hospitalization 6/15/2006 40 Male 3/15/2007 Physician France
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 4/2/2007 Physician United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 3/26/2007 71 Female 130 lb 4/13/2007 Physician United States
Primary
Concomitant
Skin Exfoliation 10/1/2005 62 Male 1/23/2007 United States
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 7/16/2007 58 Male 191 lb 7/18/2007 United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 6/15/2006 40 Male 8/23/2007 Physician France
Primary
Concomitant
Alveolitis Hospitalization 8/16/2006 47 Female 119 lb 8/24/2007 Physician Germany
Primary
Concomitant
General Physical Health Deterioration Other Serious 6/15/2006 40 Male 9/4/2007 Physician France
Primary
Concomitant
Oedema Peripheral Hospitalization 8/3/2007 80 Male 157 lb 9/10/2007 Physician Thailand
Primary
Concomitant
Oedema Peripheral Hospitalization 8/3/2007 80 Male 157 lb 9/11/2007 Physician Thailand
Primary
Concomitant
Pyrexia Hospitalization 9/10/2007 60 Male 181 lb 9/24/2007 Physician Denmark
Primary
Concomitant
Hyponatraemia Hospitalization 8/23/2007 63 Male 194 lb 10/18/2007 Physician Italy
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/23/2007 63 Male 194 lb 10/22/2007 Physician Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 11/16/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/6/2006 59 Male 174 lb 12/28/2007 Physician United States
Primary
Concomitant
Hypophosphataemia Other Serious 8/23/2007 63 Male 194 lb 1/7/2008 Physician Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 1/22/2008 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 8/3/2007 80 Male 157 lb 2/1/2008 Physician Thailand
Primary
Concomitant
Oedema Peripheral Hospitalization 8/3/2007 80 Male 157 lb 2/7/2008 Physician Thailand
Primary
Concomitant
Renal Failure Other Serious 4/10/2007 74 Female 119 lb 3/20/2008 Physician United States
Primary
Secondary
Concomitant
Lobar Pneumonia Hospitalization 4/18/2008 66 Male 231 lb 5/6/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/10/2007 74 Female 119 lb 5/6/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/10/2007 74 Female 119 lb 4/9/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/9/2008 49 Female 143 lb 5/20/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/7/2008 49 Female 143 lb 5/20/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/7/2008 49 Female 143 lb 6/17/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 66 Male 229 lb 6/20/2008 Consumer United States
Primary
Secondary
Concomitant
Metastatic Renal Cell Carcinoma Hospitalization 6/22/2006 Male 6/20/2008 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 6/12/2008 73 Male 170 lb 6/26/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/10/2007 60 Male 181 lb 7/31/2008 Physician Denmark
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 9/8/2008 61 Male 141 lb 10/1/2008 United States
Primary
Secondary
Concomitant
Metastatic Renal Cell Carcinoma Hospitalization 6/22/2006 Male 10/7/2008 Physician United States
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 9/8/2008 61 Male 141 lb 10/17/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/20/2007 63 Female 220 lb 10/28/2008 Other Health Professional United States
Primary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 6/8/2007 73 Female 150 lb 10/31/2008 Physician Germany
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 9/3/2008 61 Male 141 lb 11/4/2008 United States
Primary
Secondary
Concomitant
Interacting
Upper Gastrointestinal Haemorrhage Other Serious 9/3/2008 61 Male 141 lb 11/5/2008 United States
Primary
Secondary
Concomitant
Interacting
Hepatic Neoplasm Malignant Life Threatening 6/8/2007 73 Female 150 lb 12/5/2008 Physician Germany
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 11/13/2008 54 Male 194 lb 12/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Lumbar Vertebral Fracture Hospitalization 12/10/2008 63 Female 196 lb 2/19/2009 Physician France
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 1/29/2009 80 Male 161 lb 2/26/2009 Other Health Professional Australia
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 11/28/2008 49 Female 121 lb 3/17/2009 Physician France
Primary
Concomitant
Vitreous Haemorrhage Other Serious 8/19/2008 66 Male 3/19/2009 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 2/21/2009 48 Male 148 lb 3/25/2009 Physician United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 9/27/2008 66 Male 3/30/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/11/2009 43 Male 4/1/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Vomiting Other Serious 10/6/2006 59 Male 174 lb 4/9/2009 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/18/2008 76 Male 141 lb 4/9/2009 United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 3/16/2009 81 Male 4/9/2009 Physician Italy
Primary
Concomitant
Rectal Haemorrhage Hospitalization 2/11/2009 43 Male 4/16/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Lymphopenia Hospitalization 2/20/2009 81 Male 143 lb 4/21/2009 Physician Italy
Primary
Concomitant
Hiccups Hospitalization 3/18/2009 66 Male 139 lb 4/22/2009 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 6/12/2008 73 Male 170 lb 4/30/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/6/2006 59 Male 174 lb 5/15/2009 Physician United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 11/28/2008 49 Female 121 lb 5/20/2009 Physician France
Primary
Concomitant
Radiation Skin Injury 5/12/2009 50 Female 229 lb 5/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 5/22/2009 67 Female 194 lb 5/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Hospitalization 5/21/2009 68 Female 194 lb 6/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Radiation Skin Injury 5/12/2009 50 Female 229 lb 6/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/22/2009 67 Female 194 lb 6/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/21/2009 68 Female 194 lb 6/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rash 5/12/2009 50 Female 229 lb 6/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Dysplastic Naevus Syndrome Other Serious Male 194 lb 6/24/2009 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 5/26/2009 47 Male 6/30/2009 Physician Australia
Primary
Concomitant
Liver Function Test Abnormal Death 6/28/2009 58 Female 120 lb 7/16/2009 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/21/2009 68 Female 194 lb 7/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/1/2009 Male 194 lb 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 7/12/2008 Male 157 lb 7/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/3/2008 61 Male 141 lb 8/3/2009 United States
Primary
Secondary
Concomitant
Interacting
Lymphopenia Hospitalization 2/20/2009 81 Male 143 lb 8/11/2009 Physician Italy
Primary
Concomitant
Vomiting Hospitalization 7/4/2009 Male 193 lb 9/1/2009 Physician United States
Primary
Secondary
Concomitant
Metastatic Renal Cell Carcinoma Other Serious 1/29/2009 80 Male 161 lb 9/2/2009 Other Health Professional Australia
Primary
Concomitant
Vomiting Hospitalization 7/4/2009 Male 193 lb 9/2/2009 Physician United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Other Serious 6/12/2008 73 Male 170 lb 9/11/2009 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 7/26/2009 62 Female 225 lb 9/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 9/9/2009 77 Male 269 lb 9/23/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2009 Male 193 lb 10/15/2009 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 9/9/2009 77 Male 269 lb 11/2/2009 Physician United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 3/26/2007 71 Female 130 lb 11/4/2009 Physician United States
Primary
Concomitant
Varices Oesophageal Other Serious 8/30/2009 55 Male 11/6/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/4/2009 64 Female 146 lb 11/17/2009 Physician Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/30/2009 76 Male 2/8/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/30/2009 55 Male 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 3/31/2010 69 Male 106 lb 5/21/2010 Physician France
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 4/29/2010 59 Female 157 lb 6/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/16/2010 41 Male 6/16/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 7/1/2009 48 Male 254 lb 6/23/2010 Physician Australia
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 4/28/2010 64 Male 7/7/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Presyncope Hospitalization 5/24/2010 70 Male 165 lb 7/26/2010 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 3/31/2010 69 Male 106 lb 8/3/2010 Physician France
Primary
Secondary
Concomitant
Pain Hospitalization 7/24/2010 78 Male 132 lb 8/10/2010 Ireland
Primary
Concomitant
Pain Hospitalization 7/24/2010 78 Male 132 lb 8/11/2010 Ireland
Primary
Concomitant
Toe Amputation Other Serious 6/3/2010 57 Male 9/1/2010 Physician France
Primary
Secondary
Concomitant
Peritonitis Life Threatening 8/20/2010 72 Male 9/3/2010 Physician Germany
Primary
Concomitant
Toe Amputation Other Serious 6/3/2010 57 Male 9/7/2010 Physician France
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 9/13/2010 67 Female 163 lb 10/4/2010 Physician France
Primary
Concomitant
Pleural Effusion Hospitalization 2/24/2010 69 Male 106 lb 10/15/2010 Physician France
Primary
Secondary
Concomitant
Dyslipidaemia Other Serious 10/11/2010 47 Female 115 lb 11/5/2010 Physician Switzerland
Primary
Secondary
Concomitant
Generalised Oedema Hospitalization 2/15/2010 68 Male 234 lb 11/5/2010 Physician France
Primary
Concomitant

Drug Data