Nexavar combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain Hospitalization 1/14/2006 81 Female 137 lb 2/2/2006 United States
Primary
Concomitant
Oedema Peripheral Other Serious 2/11/2006 65 Male 269 lb 3/24/2006 United States
Primary
Concomitant
Ulcer Haemorrhage Hospitalization 70 Female 5/1/2006 United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 12/1/2005 73 Male 163 lb 5/3/2006 Physician United States
Primary
Concomitant
Ulcer Haemorrhage Hospitalization 70 Female 5/24/2006 Consumer United States
Primary
Concomitant
Skin Exfoliation Hospitalization 3/20/2006 81 Male 6/29/2006 United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 12/1/2005 74 Male 6/30/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 2/1/2006 64 Female 140 lb 7/10/2006 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 9/1/2005 70 Female 5/31/2006 Other Health Professional United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 10/1/2005 70 Female 5/31/2006 Other Health Professional United States
Primary
Concomitant
Skin Ulcer 70 Female 5/31/2006 Physician United States
Primary
Concomitant
Femur Fracture Hospitalization 10/1/2005 78 Male 7/26/2006 Other Health Professional United States
Primary
Concomitant
Rash Erythematous 3/28/2006 78 Female 165 lb 7/12/2006 United States
Primary
Concomitant
Sinus Headache 2/1/2006 75 Male 7/12/2006 United States
Primary
Concomitant
Muscular Weakness 4/1/2006 56 Male 7/12/2006 United States
Primary
Concomitant
Tongue Disorder Other Serious 3/11/2006 58 Female 148 lb 7/12/2006 United States
Primary
Concomitant
Skin Exfoliation Hospitalization 3/20/2006 81 Male 185 lb 8/17/2006 Consumer United States
Primary
Secondary
Concomitant
Ulcer Haemorrhage Hospitalization 70 Female 9/22/2006 Consumer United States
Primary
Concomitant
Femur Fracture Hospitalization 10/1/2005 78 Male 10/4/2006 Other Health Professional United States
Primary
Concomitant
Vocal Cord Disorder 2/16/2006 69 Male 212 lb 10/18/2006 United States
Primary
Concomitant
Vision Blurred Other Serious 9/4/2006 62 Female 150 lb 11/7/2006 United States
Primary
Concomitant
Vomiting Hospitalization 2/1/2006 75 Male 146 lb 11/8/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2006 76 Male 146 lb 11/27/2006 Consumer United States
Primary
Concomitant
Facial Pain Hospitalization 2/1/2006 69 Male 207 lb 1/11/2007 United States
Primary
Secondary
Concomitant
Vomiting 3/28/2006 78 Female 141 lb 10/23/2006 United States
Primary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 3/11/2006 58 Female 150 lb 10/23/2006 United States
Primary
Concomitant
Facial Pain Other Serious 2/1/2006 69 Male 207 lb 2/6/2007 United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 1/29/2007 Male 2/19/2007 Consumer United States
Primary
Concomitant
Facial Pain Other Serious 2/1/2006 69 Male 207 lb 3/9/2007 United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 1/29/2007 64 Male 181 lb 3/22/2007 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 1/5/2007 75 Male 187 lb 4/17/2007 France
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 1/29/2007 64 Male 181 lb 5/7/2007 Other Health Professional United States
Primary
Concomitant
Vomiting 3/28/2006 78 Female 141 lb 1/23/2007 United States
Primary
Concomitant
Rash Pruritic Female 1/23/2007 Consumer United States
Primary
Concomitant
Pigmentation Disorder 10/19/2006 34 Male 1/23/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2006 76 Male 146 lb 5/14/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/23/2007 74 Female 5/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/1/2006 57 Female 134 lb 5/31/2007 United States
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 3/20/2006 81 Male 185 lb 7/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2007 74 Female 8/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2007 74 Female 8/21/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 12/1/2006 Female 8/23/2007 Consumer Germany
Primary
Concomitant
Vomiting Hospitalization 5/1/2007 74 Female 9/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 67 Male 180 lb 10/12/2007 United States
Primary
Concomitant
Diarrhoea Hospitalization 1/10/2007 57 Male 11/30/2007 Physician Italy
Primary
Concomitant
Subcutaneous Abscess Hospitalization 1/27/2008 56 Female 217 lb 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/26/2008 56 Female 217 lb 3/10/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/6/2008 56 Female 3/21/2008 United States
Primary
Concomitant
Haemolytic Anaemia Hospitalization 5/23/2008 53 Male 6/10/2008 United States
Primary
Secondary
Concomitant
Streptococcal Infection Death 4/20/2008 54 Male 130 lb 6/18/2008 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 45 Female 6/18/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2007 72 Male 6/19/2008 United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/3/2008 77 Male 146 lb 6/20/2008 Physician Japan
Primary
Concomitant
Rash Other Serious 4/29/2008 70 Male 6/25/2008 Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 45 Female 115 lb 6/26/2008 Consumer United States
Primary
Concomitant
Stomatitis Death 4/20/2008 54 Male 130 lb 6/30/2008 Physician Japan
Primary
Concomitant
Haemoptysis Hospitalization 5/23/2008 53 Male 7/2/2008 United States
Primary
Secondary
Concomitant
Rash Other Serious 4/29/2008 70 Male 7/14/2008 Japan
Primary
Concomitant
Rash Other Serious 4/29/2008 70 Male 8/11/2008 Japan
Primary
Concomitant
Surgery Hospitalization Male 8/15/2008 Other Health Professional United States
Primary
Concomitant
Surgery Hospitalization Male 8/15/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 3/6/2008 56 Female 9/5/2008 United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 7/19/2008 77 Male 176 lb 9/9/2008 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/24/2008 61 Male 106 lb 9/9/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/28/2008 53 Female 112 lb 9/10/2008 Physician Japan
Primary
Concomitant
Cerebrovascular Accident Hospitalization Female 161 lb 9/23/2008 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 45 Female 115 lb 9/30/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2007 72 Male 9/30/2008 United States
Primary
Concomitant
Rash Hospitalization 7/24/2008 61 Male 106 lb 10/2/2008 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 7/19/2008 77 Male 176 lb 10/7/2008 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 6/12/2008 82 Female 110 lb 10/9/2008 Physician Japan
Primary
Concomitant
Rash Other Serious 7/18/2008 73 Female 130 lb 10/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rash 7/18/2008 73 Female 130 lb 11/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2006 48 Male 154 lb 11/18/2008 Physician Switzerland
Primary
Secondary
Tooth Extraction Other Serious 1/1/2006 Male 11/18/2008 Other Health Professional Switzerland
Primary
Secondary
Weight Decreased Other Serious 6/12/2008 82 Female 110 lb 11/19/2008 Physician Japan
Primary
Concomitant
Sudden Death Death 11/16/2008 70 Male 121 lb 12/1/2008 Physician Japan
Primary
Concomitant
Sudden Death Death 10/20/2008 75 Male 12/1/2008 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2006 50 Male 1543 lb 11/26/2008 Physician Switzerland
Primary
Secondary
Hepatic Function Abnormal Hospitalization 8/1/2008 60 Male 130 lb 12/4/2008 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 7/19/2008 77 Male 176 lb 12/8/2008 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 7/22/2008 61 Male 148 lb 12/10/2008 Physician Japan
Primary
Concomitant
Tumour Haemorrhage Life Threatening 10/31/2008 57 Male 141 lb 12/11/2008 Physician Japan
Primary
Concomitant
Tumour Haemorrhage Life Threatening 10/31/2008 57 Male 141 lb 12/12/2008 Physician Japan
Primary
Concomitant
Tumour Haemorrhage Life Threatening 10/31/2008 57 Male 141 lb 12/22/2008 Physician Japan
Primary
Concomitant
Tumour Haemorrhage Life Threatening 10/31/2008 57 Male 141 lb 1/6/2009 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2006 50 Male 154 lb 1/7/2009 Physician Switzerland
Primary
Secondary
Bone Disorder Other Serious Male 1/16/2009 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2006 48 Male 154 lb 1/20/2009 Physician Switzerland
Primary
Secondary
Osteonecrosis Other Serious 1/1/2006 50 Male 154 lb 1/20/2009 Physician Switzerland
Primary
Secondary
Tooth Extraction Other Serious 1/1/2007 Male 1/28/2009 Other Health Professional Switzerland
Primary
Secondary
Weight Decreased Other Serious 6/12/2008 82 Female 110 lb 1/28/2009 Physician Japan
Primary
Concomitant
Condition Aggravated Other Serious 1/1/2007 49 Male 154 lb 1/30/2009 Physician Switzerland
Primary
Secondary
Rash Hospitalization 7/24/2008 61 Male 106 lb 2/9/2009 Physician Japan
Primary
Secondary
Concomitant
Angioedema Hospitalization 8/10/2008 68 Male 3/3/2009 Physician Germany
Primary
Secondary
Concomitant
Angioedema Hospitalization 8/10/2008 68 Male 3/10/2009 Other Health Professional
Primary
Secondary
Concomitant
Speech Disorder Other Serious 6/20/2007 Female 161 lb 3/24/2009 Physician Germany
Primary
Concomitant
Stomatitis Other Serious 7/8/2008 69 Male 132 lb 4/2/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/4/2009 79 Male 152 lb 4/14/2009 Physician Japan
Primary
Concomitant
Renal Haemorrhage Other Serious 5/7/2008 70 Male 4/14/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/28/2008 53 Female 112 lb 4/15/2009 Physician Japan
Primary
Concomitant
Visual Impairment Other Serious 81 Female 4/30/2009 Physician Israel
Primary
Concomitant
Renal Haemorrhage Other Serious 5/7/2008 70 Male 5/26/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/22/2008 73 Female 134 lb 6/5/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/22/2008 73 Female 134 lb 6/12/2009 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 9/12/2008 82 Male 95 lb 6/17/2009 Physician Japan
Primary
Concomitant
Vaginal Discharge Other Serious 12/9/2008 61 Female 141 lb 6/30/2009 United States
Primary
Concomitant
Pyrexia Life Threatening 9/12/2008 82 Male 95 lb 7/2/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/28/2008 53 Female 112 lb 7/2/2009 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 6/12/2008 82 Female 110 lb 7/6/2009 Physician Japan
Primary
Concomitant
Vaginal Discharge Other Serious 10/14/2008 61 Female 141 lb 7/7/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/28/2008 53 Female 112 lb 7/8/2009 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 7/1/2009 74 Male 148 lb 7/20/2009 Physician Japan
Primary
Secondary
Sudden Death Death 11/16/2008 70 Male 121 lb 7/28/2009 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 10/1/2007 72 Male 8/14/2009 United States
Primary
Concomitant
Osteomyelitis Other Serious 6/6/2008 Male 8/20/2009 Other Health Professional Italy
Primary
Concomitant
Pyrexia Other Serious 6/2/2009 46 Male 157 lb 8/24/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/4/2009 79 Male 152 lb 8/31/2009 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 10/1/2007 72 Male 9/1/2009 United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/23/2009 75 Male 117 lb 9/3/2009 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 7/1/2009 74 Male 148 lb 9/10/2009 Physician Japan
Primary
Secondary
Pyrexia Other Serious 9/17/2009 61 Female 9/21/2009 Greece
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/25/2008 61 Female 121 lb 10/8/2009 Physician Japan
Primary
Concomitant
Troponin T Increased Other Serious Male 10/22/2009 Physician Austria
Primary
Secondary
Concomitant
Hypophosphataemia Other Serious 8/10/2009 69 Female 10/23/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/17/2009 61 Female 11/2/2009 Greece
Primary
Concomitant
Hypertension Death 8/25/2009 62 Male 11/4/2009 Physician Japan
Primary
Concomitant
Hypophosphataemia Other Serious 8/10/2009 69 Female 11/11/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/25/2008 63 Female 101 lb 11/16/2009 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/25/2008 61 Female 121 lb 11/16/2009 Physician Japan
Primary
Concomitant
Stomatitis Disability 8/12/2009 39 Female 112 lb 12/28/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/27/2009 62 Male 12/29/2009 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 5/22/2009 58 Male 79 lb 12/29/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/17/2009 61 Female 12/31/2009 Greece
Primary
Concomitant
Rash Hospitalization 7/24/2008 61 Male 106 lb 1/6/2010 Physician Japan
Primary
Secondary
Concomitant
Metastases To Bone Other Serious 55 Male 2/1/2010 Other Health Professional Japan
Primary
Concomitant
Tooth Infection Other Serious 3/8/2006 Male 2/4/2010 Other Health Professional United States
Primary
Concomitant
Radiotherapy Other Serious 55 Male 2/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Yellow Skin Other Serious 8/6/2008 56 Female 99 lb 2/9/2010 Physician Japan
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/11/2010 Physician United States
Primary
Concomitant
Tumour Haemorrhage Life Threatening 10/31/2008 57 Male 141 lb 2/12/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 12/29/2009 66 Male 123 lb 2/17/2010 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 Male 200 lb 2/18/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/18/2010 Physician United States
Primary
Concomitant
Stomatitis Other Serious 7/22/2008 73 Female 134 lb 2/22/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/8/2008 69 Male 132 lb 2/22/2010 Physician Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 3/8/2006 Male 2/24/2010 Other Health Professional United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/26/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/2/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 61 Male 148 lb 3/4/2010 Physician Japan
Primary
Concomitant

Drug Data