Nexavar combined with Urepearl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lower Gastrointestinal Haemorrhage Hospitalization 2/20/2009 67 Female 97 lb 3/30/2009 Physician Japan
Primary
Concomitant
Shock Life Threatening 3/13/2009 76 Male 123 lb 5/15/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 12/19/2008 56 Male 148 lb 6/10/2009 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 5/29/2009 69 Male 7/8/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 12/19/2008 56 Male 148 lb 7/9/2009 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 7/2/2009 66 Female 7/31/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/1/2009 85 Female 106 lb 8/14/2009 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 7/9/2009 74 Male 152 lb 8/17/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 7/22/2009 49 Male 132 lb 8/17/2009 Physician Japan
Primary
Concomitant
Shock Life Threatening 3/13/2009 76 Male 123 lb 8/18/2009 Physician Japan
Primary
Concomitant
Shock Life Threatening 3/13/2009 76 Male 123 lb 8/19/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/15/2008 71 Male 121 lb 8/20/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/2/2009 66 Female 112 lb 8/26/2009 Physician Japan
Primary
Concomitant
Varices Oesophageal Hospitalization 7/25/2009 55 Female 123 lb 9/9/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 7/24/2009 70 Male 9/10/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/15/2008 71 Male 121 lb 9/10/2009 Physician Japan
Primary
Concomitant
Varices Oesophageal Other Serious 7/25/2009 55 Female 123 lb 9/16/2009 Physician Japan
Primary
Concomitant
Truncus Coeliacus Thrombosis Hospitalization 7/8/2009 70 Male 106 lb 9/29/2009 Pharmacist Japan
Primary
Concomitant
Rash Hospitalization 7/25/2009 55 Female 123 lb 10/7/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/19/2009 69 Male 168 lb 10/7/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/30/2009 55 Male 161 lb 10/9/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/29/2008 69 Male 119 lb 10/9/2009 Physician Japan
Primary
Concomitant
Rash Death 7/2/2009 66 Female 112 lb 10/16/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 8/17/2009 82 Male 99 lb 10/16/2009 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/26/2009 61 Male 126 lb 10/30/2009 Physician Japan
Primary
Concomitant
Pyrexia 7/24/2009 70 Male 11/13/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/26/2009 61 Male 126 lb 11/30/2009 Physician Japan
Primary
Concomitant
Hypertension Death 9/20/2009 57 Male 176 lb 12/3/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/26/2009 85 Male 123 lb 12/3/2009 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 9/22/2009 67 Male 126 lb 12/8/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 10/15/2009 54 Male 176 lb 12/8/2009 Physician Japan
Primary
Concomitant
Rash Other Serious 7/2/2009 66 Female 112 lb 12/18/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 9/24/2009 67 Male 130 lb 12/22/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/26/2009 85 Male 123 lb 12/28/2009 Physician Japan
Primary
Concomitant
Hepatic Failure Death 12/18/2009 64 Male 1/8/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/26/2009 61 Male 126 lb 1/11/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 1/18/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 1/19/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/16/2009 78 Female 112 lb 1/25/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 1/25/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/30/2009 55 Male 161 lb 2/9/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/31/2009 59 Male 172 lb 2/11/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/26/2009 61 Male 126 lb 2/11/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 8/16/2009 74 Male 106 lb 2/12/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/1/2009 85 Female 106 lb 2/15/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 8/23/2009 74 Male 181 lb 2/17/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/1/2009 85 Female 106 lb 2/23/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 11/22/2009 61 Male 146 lb 2/24/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 7/2/2009 66 Female 112 lb 3/4/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 9/2/2009 58 Male 152 lb 3/9/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/30/2009 55 Male 161 lb 3/10/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 3/26/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 3/30/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/26/2009 61 Male 126 lb 4/6/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/16/2009 78 Female 112 lb 4/12/2010 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 12/3/2009 71 Male 141 lb 4/13/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/24/2010 89 Male 121 lb 4/14/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 8/16/2009 74 Male 106 lb 4/20/2010 Physician Japan
Primary
Concomitant
Rash Death 8/19/2009 57 Male 141 lb 4/20/2010 Physician Japan
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 11/22/2009 61 Male 146 lb 4/28/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 12/28/2009 56 Female 101 lb 4/29/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 12/3/2009 71 Male 141 lb 4/30/2010 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 6/1/2009 56 Male 157 lb 5/5/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 7/6/2009 69 Male 139 lb 5/7/2010 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 6/1/2009 56 Male 157 lb 5/11/2010 Physician Japan
Primary
Concomitant
Weight Decreased Death 12/3/2009 71 Male 141 lb 5/12/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 12/28/2009 56 Female 101 lb 5/21/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 3/13/2009 76 Male 123 lb 5/21/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/1/2009 85 Female 106 lb 5/21/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 7/9/2009 74 Male 152 lb 5/21/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/31/2009 59 Male 172 lb 5/24/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/17/2009 75 Female 5/27/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 8/11/2009 58 Male 170 lb 6/1/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 9/28/2009 63 Male 6/1/2010 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 12/26/2009 81 Male 117 lb 6/16/2010 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 2/2/2010 77 Male 141 lb 6/16/2010 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2009 67 Male 6/23/2010 Physician Japan
Primary
Concomitant
Weight Decreased 2/2/2010 77 Male 141 lb 7/1/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/30/2009 55 Male 161 lb 7/7/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/26/2009 61 Male 126 lb 7/7/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 7/7/2010 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 6/1/2009 56 Male 157 lb 7/12/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 9/2/2009 58 Male 152 lb 7/12/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Hospitalization 12/25/2009 73 Male 137 lb 7/12/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 11/30/2009 27 Female 123 lb 7/12/2010 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2009 67 Male 7/13/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 7/22/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 9/22/2009 67 Male 126 lb 7/27/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Hospitalization 12/25/2009 73 Male 137 lb 7/28/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/2/2009 82 Female 7/28/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 9/22/2009 67 Male 126 lb 7/29/2010 Physician Japan
Primary
Concomitant
Renal Disorder Life Threatening 7/23/2009 68 Male 141 lb 7/27/2010 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/22/2010 76 Male 141 lb 7/30/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/3/2009 64 Male 128 lb 8/2/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 7/2/2009 66 Female 112 lb 8/2/2010 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 9/1/2009 67 Male 8/4/2010 Physician Japan
Primary
Concomitant
Parkinson's Disease Hospitalization 10/15/2009 54 Male 176 lb 8/10/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/3/2009 64 Male 128 lb 8/12/2010 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 5/29/2009 69 Male 132 lb 8/12/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 7/2/2009 66 Female 112 lb 8/12/2010 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 2/24/2010 89 Male 121 lb 8/20/2010 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 9/1/2009 67 Male 8/24/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Death 5/28/2010 80 Male 99 lb 8/26/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/19/2009 82 Female 86 lb 8/31/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 7/22/2009 49 Male 132 lb 9/1/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 7/9/2009 74 Male 152 lb 9/3/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/20/2009 77 Female 9/3/2010 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 5/29/2009 69 Male 132 lb 9/8/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 9/2/2009 58 Male 152 lb 9/8/2010 Physician Japan
Primary
Concomitant
Parkinson's Disease Hospitalization 10/15/2009 54 Male 176 lb 9/8/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 5/6/2010 45 Male 139 lb 9/20/2010 Physician Japan
Primary
Concomitant
Truncus Coeliacus Thrombosis Hospitalization 7/15/2009 70 Male 106 lb 9/20/2010 Pharmacist Japan
Primary
Concomitant
Parkinsonism Hospitalization 10/15/2009 54 Male 176 lb 9/22/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/30/2009 55 Male 161 lb 9/22/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 9/14/2010 77 Male 104 lb 10/6/2010 Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 9/1/2009 67 Male 10/7/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 7/9/2009 74 Male 152 lb 10/15/2010 Physician Japan
Primary
Concomitant
Pneumonia Life Threatening 7/22/2009 49 Male 132 lb 10/15/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 9/2/2009 58 Male 152 lb 10/18/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 9/2/2009 58 Male 152 lb 10/20/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 9/2/2009 58 Male 152 lb 10/29/2010 Physician Japan
Primary
Concomitant
Dizziness Hospitalization 10/1/2010 78 Female 97 lb 10/29/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 12/28/2009 56 Female 101 lb 10/29/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome 8/1/2010 70 Male 143 lb 11/4/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/2/2009 82 Female 11/16/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/1/2009 85 Female 106 lb 11/18/2010 Physician Japan
Primary
Concomitant
Pneumonia Life Threatening 7/22/2009 49 Male 132 lb 11/18/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 3/27/2010 65 Male 165 lb 11/19/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/25/2009 59 Male 172 lb 11/19/2010 Physician Japan
Primary
Concomitant
Urticaria Chronic Other Serious 7/2/2009 66 Female 112 lb 11/23/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 2/18/2010 66 Male 119 lb 12/3/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 7/9/2009 74 Male 152 lb 11/30/2010 Japan
Primary
Concomitant
Rash Hospitalization 7/3/2009 76 Male 119 lb 12/21/2010 Physician Japan
Primary
Concomitant
Tumour Rupture Hospitalization 7/4/2010 86 Female 104 lb 12/21/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 8/14/2009 80 Female 104 lb 12/27/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 9/28/2009 62 Male 12/29/2010 Physician Japan
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 9/24/2009 66 Male 130 lb 1/12/2011 Physician Japan
Primary
Concomitant
Ascites Other Serious 10/31/2009 69 Female 157 lb 2/2/2011 Physician Japan
Primary
Concomitant
Oedema Hospitalization 6/15/2008 71 Male 121 lb 2/9/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Hospitalization 10/1/2010 84 Male 146 lb 2/9/2011 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 11/7/2010 61 Female 95 lb 2/11/2011 Physician Japan
Primary
Concomitant
Shock Life Threatening 3/13/2009 75 Male 123 lb 2/18/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 8/2/2009 81 Female 2/21/2011 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Death 8/31/2009 58 Male 172 lb 2/23/2011 Physician Japan
Primary
Concomitant
Dehydration Other Serious 11/7/2010 61 Female 95 lb 2/24/2011 Physician Japan
Primary
Concomitant
Hypertension Other Serious 12/4/2008 62 Female 99 lb 3/11/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 2/20/2009 67 Female 96 lb 3/11/2011 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 7/1/2010 66 Male 4/7/2011 Physician Japan
Primary
Concomitant
Dizziness Hospitalization 4/4/2011 81 Female 4/8/2011 Physician Japan
Primary
Concomitant
Hypertension Hospitalization 9/2/2009 58 Male 152 lb 4/8/2011 Other Health Professional Japan
Primary
Concomitant

Drug Data