Nexavar combined with Takepron

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyperglycaemia Hospitalization 6/13/2008 66 Male 157 lb 7/8/2008 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 7/19/2008 77 Male 176 lb 12/8/2008 Physician Japan
Primary
Concomitant
Tuberculosis Other Serious 9/18/2008 76 Male 121 lb 12/12/2008 Physician Japan
Primary
Concomitant
Interacting
Tuberculosis Other Serious 7/4/2008 76 Male 121 lb 1/6/2009 Physician Japan
Primary
Concomitant
Interacting
Tuberculosis Other Serious 7/4/2008 76 Male 121 lb 1/8/2009 Physician Japan
Primary
Concomitant
Interacting
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/13/2008 64 Male 137 lb 1/9/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/13/2009 73 Male 99 lb 2/3/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/13/2009 73 Male 99 lb 2/11/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 6/20/2008 65 Male 123 lb 2/17/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 12/18/2008 42 Female 95 lb 2/20/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Other Serious 8/29/2008 82 Female 3/5/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 8/14/2008 74 Male 99 lb 3/5/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 8/14/2008 74 Male 99 lb 3/24/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 8/14/2008 74 Male 99 lb 3/31/2009 Physician Japan
Primary
Concomitant
Tumour Excision Hospitalization 7/22/2008 66 Male 126 lb 4/2/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/13/2009 73 Male 99 lb 4/16/2009 Physician Japan
Primary
Concomitant
Rash Other Serious 12/14/2008 61 Male 134 lb 4/24/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 9/8/2008 53 Female 97 lb 5/19/2009 Physician Japan
Primary
Concomitant
Tumour Excision Hospitalization 7/22/2008 66 Male 126 lb 5/21/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 12/19/2008 56 Male 148 lb 6/10/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 8/14/2008 74 Male 99 lb 6/17/2009 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 4/27/2009 69 Male 150 lb 6/17/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 12/19/2008 56 Male 148 lb 7/9/2009 Physician Japan
Primary
Concomitant
Malaise Life Threatening 6/24/2009 75 Male 130 lb 7/17/2009 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 5/12/2008 79 Male 126 lb 7/22/2009 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 5/12/2008 79 Male 126 lb 7/28/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 8/29/2008 68 Male 146 lb 7/29/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/3/2009 64 Male 128 lb 8/4/2009 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 5/12/2008 79 Male 126 lb 8/6/2009 Physician Japan
Primary
Concomitant
Protein Urine Other Serious 4/25/2008 68 Male 110 lb 8/7/2009 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Death 6/27/2009 52 Female 88 lb 8/11/2009 Physician Japan
Primary
Concomitant
Malaise Death 6/24/2009 75 Male 130 lb 8/17/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 6/2/2009 46 Male 157 lb 8/24/2009 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Death 8/6/2009 67 Male 121 lb 8/24/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/2/2009 66 Female 112 lb 8/26/2009 Physician Japan
Primary
Concomitant
Malaise Hospitalization 7/2/2009 80 Male 117 lb 8/27/2009 Physician Japan
Primary
Concomitant
Malaise Death 6/24/2009 75 Male 126 lb 9/3/2009 Physician Japan
Primary
Concomitant
Renal Failure Life Threatening 7/9/2009 70 Male 121 lb 9/3/2009 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 7/3/2009 77 Male 110 lb 9/4/2009 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 8/21/2008 68 Male 146 lb 9/8/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2009 79 Female 9/16/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/24/2009 76 Male 119 lb 9/18/2009 Physician Japan
Primary
Concomitant
Malaise Hospitalization 8/19/2009 56 Male 168 lb 9/21/2009 Physician Japan
Primary
Concomitant
Tuberculosis Other Serious 7/4/2008 76 Male 121 lb 9/21/2009 Physician Japan
Primary
Concomitant
Interacting
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/24/2009 68 Female 106 lb 9/24/2009 Physician Japan
Primary
Concomitant
Rash Other Serious 6/30/2008 81 Male 121 lb 9/25/2009 Physician Japan
Primary
Concomitant
Rash Other Serious 6/30/2008 81 Male 121 lb 10/1/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 8/11/2009 61 Male 161 lb 10/2/2009 Physician Japan
Primary
Concomitant
Rash Death 7/2/2009 66 Female 112 lb 10/16/2009 Physician Japan
Primary
Concomitant
Malaise Death 6/24/2009 75 Male 126 lb 10/22/2009 Physician Japan
Primary
Concomitant
Pruritus Other Serious 7/26/2009 48 Male 123 lb 11/23/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/15/2008 60 Male 143 lb 11/24/2009 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening 8/26/2009 71 Male 128 lb 11/24/2009 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 6/24/2009 78 Male 121 lb 11/25/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/26/2009 61 Male 126 lb 11/30/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Death 9/12/2009 65 Male 12/3/2009 Physician Japan
Primary
Concomitant
Rash Other Serious 9/16/2009 76 Male 99 lb 12/3/2009 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/24/2009 73 Male 119 lb 12/4/2009 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 10/13/2009 66 Male 157 lb 12/4/2009 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 9/22/2009 67 Male 126 lb 12/8/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/13/2009 73 Male 99 lb 12/8/2009 Physician Japan
Primary
Concomitant
Red Blood Cell Count Decreased Life Threatening 9/17/2009 Male 137 lb 12/10/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 9/25/2009 77 Male 152 lb 12/15/2009 Physician Japan
Primary
Concomitant
Malaise Hospitalization 7/2/2009 80 Male 117 lb 12/16/2009 Physician Japan
Primary
Concomitant
Tremor Hospitalization 3/14/2009 78 Male 137 lb 12/18/2009 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/24/2009 68 Female 106 lb 12/18/2009 Physician Japan
Primary
Secondary
Concomitant
Malaise Life Threatening 6/24/2009 75 Male 126 lb 12/21/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/15/2008 60 Male 143 lb 12/22/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/27/2009 52 Female 117 lb 12/22/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 9/28/2009 77 Male 152 lb 12/22/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/19/2009 72 Male 165 lb 12/28/2009 Physician Japan
Primary
Concomitant
Erythema Multiforme Other Serious 10/13/2009 73 Female 110 lb 12/28/2009 Physician Japan
Primary
Concomitant
Red Blood Cell Count Abnormal Hospitalization 1/13/2009 76 Female 101 lb 1/6/2010 Physician Japan
Primary
Concomitant
Red Blood Cell Count Abnormal Hospitalization 1/13/2009 76 Female 101 lb 1/7/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/26/2009 61 Male 126 lb 1/11/2010 Physician Japan
Primary
Concomitant
Red Blood Cell Count Abnormal Hospitalization 1/13/2009 76 Female 101 lb 1/14/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 9/4/2009 66 Male 128 lb 1/15/2010 Physician Japan
Primary
Concomitant
Renal Failure Life Threatening 9/17/2009 Male 137 lb 1/19/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Death 11/21/2009 71 Male 1/25/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 9/10/2009 63 Male 141 lb 2/1/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/6/2009 73 Male 123 lb 2/2/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Death 12/24/2009 69 Male 2/4/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 11/6/2009 86 Male 148 lb 2/9/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 9/28/2009 77 Male 152 lb 2/9/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Death 12/24/2009 69 Male 2/9/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/26/2009 61 Male 126 lb 2/11/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/3/2009 64 Male 128 lb 2/15/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 5/1/2008 65 Male 123 lb 2/16/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 9/28/2009 77 Male 152 lb 2/16/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 9/26/2009 56 Male 119 lb 2/19/2010 Physician Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 12/17/2009 61 Male 132 lb 3/3/2010 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 7/9/2009 70 Male 121 lb 3/8/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/23/2009 70 Male 143 lb 3/9/2010 Physician Japan
Primary
Concomitant
Pneumonia Death 8/24/2009 75 Male 117 lb 3/10/2010 Physician Japan
Primary
Concomitant
Protein Urine Other Serious 4/25/2008 68 Male 110 lb 3/11/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 12/12/2009 75 Male 134 lb 3/15/2010 Physician Japan
Primary
Concomitant
Erythema Multiforme Other Serious 9/22/2008 83 Male 3/16/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 12/18/2008 42 Female 95 lb 3/16/2010 Physician Japan
Primary
Concomitant
Protein Urine Other Serious 4/25/2008 68 Male 110 lb 3/18/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome 7/13/2009 76 Male 119 lb 3/19/2010 Physician Japan
Primary
Concomitant
Tumour Excision Hospitalization 7/22/2008 66 Male 126 lb 4/12/2010 Physician Japan
Primary
Concomitant
Renal Failure Life Threatening 9/17/2009 Male 137 lb 4/12/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/19/2009 72 Male 165 lb 4/12/2010 Physician Japan
Primary
Concomitant
Rash Life Threatening 9/21/2009 71 Male 168 lb 4/15/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/24/2009 83 Male 115 lb 4/20/2010 Physician Japan
Primary
Concomitant
Stomatitis Life Threatening 11/14/2009 76 Female 115 lb 4/20/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 5/21/2009 50 Female 101 lb 4/20/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 9/16/2009 76 Male 99 lb 4/26/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2009 66 Male 119 lb 4/29/2010 Physician Japan
Primary
Concomitant
Tumour Excision Other Serious 7/22/2008 66 Male 126 lb 5/6/2010 Physician Japan
Primary
Concomitant
Tumour Excision Other Serious 7/22/2008 66 Male 126 lb 5/7/2010 Physician Japan
Primary
Concomitant
Shock Haemorrhagic Life Threatening 12/12/2009 75 Male 134 lb 5/7/2010 Physician Japan
Primary
Concomitant
Pruritus Other Serious 7/26/2009 48 Male 123 lb 5/11/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 8/26/2009 65 Male 130 lb 5/13/2010 Physician Japan
Primary
Concomitant
Hypertension Other Serious 8/29/2008 82 Female 5/17/2010 Physician Japan
Primary
Concomitant
Hypertension Other Serious 8/29/2008 82 Female 5/18/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 1/1/2009 79 Female 5/19/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 9/2/2009 69 Male 119 lb 5/20/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 7/29/2009 73 Female 77 lb 5/24/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased 7/14/2009 74 Male 163 lb 5/24/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 8/31/2009 71 Male 168 lb 5/24/2010 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 7/31/2009 33 Male 106 lb 5/25/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 10/20/2009 76 Male 5/26/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2009 66 Male 119 lb 6/1/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 5/21/2009 50 Female 101 lb 6/1/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 11/22/2009 77 Male 132 lb 6/1/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/15/2009 81 Male 6/1/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 76 Male 150 lb 6/1/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/28/2009 77 Female 106 lb 6/1/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 11/2/2009 74 Male 148 lb 6/1/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 2/26/2010 76 Male 150 lb 6/7/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/27/2009 52 Female 119 lb 6/10/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Disability 8/28/2009 21 Male 170 lb 6/10/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 7/9/2009 69 Female 99 lb 6/10/2010 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Life Threatening 8/13/2009 55 Male 90 lb 6/16/2010 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 7/31/2009 33 Male 106 lb 6/24/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/23/2009 70 Male 143 lb 6/29/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 5/30/2010 81 Male 119 lb 7/5/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 6/26/2009 80 Male 97 lb 7/7/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/26/2009 61 Male 126 lb 7/7/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/24/2009 83 Male 115 lb 7/7/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 7/2/2009 68 Male 126 lb 7/12/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 2/16/2010 76 Male 137 lb 7/12/2010 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 7/31/2009 33 Male 106 lb 7/12/2010 Physician Japan
Primary
Concomitant
Thyroid Disorder Other Serious 12/18/2008 42 Female 95 lb 7/14/2010 Japan
Primary
Concomitant
Malaise Hospitalization 4/15/2010 82 Male 115 lb 7/19/2010 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 7/3/2009 80 Male 117 lb 7/22/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 9/22/2009 67 Male 126 lb 7/27/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/15/2009 81 Male 7/26/2010 Physician Japan
Primary
Concomitant
Skin Disorder Other Serious 8/12/2009 79 Male 108 lb 7/28/2010 Physician Japan
Primary
Concomitant

Drug Data