Nexavar combined with Sutent

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Medication Error 5/3/2006 Pharmacist United States
Primary
Secondary
Monoplegia Disability 3/1/2007 52 Male 148 lb 4/10/2007 Consumer France
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Disability 3/1/2007 52 Male 148 lb 5/3/2007 Consumer France
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Disability 3/1/2007 52 Male 148 lb 5/7/2007 Consumer France
Primary
Concomitant
Retinal Vein Thrombosis Other Serious 30 Male 8/20/2007 Physician France
Primary
Concomitant
Retinal Vein Thrombosis Other Serious 30 Male 8/22/2007 Physician France
Primary
Concomitant
Retinal Vein Thrombosis Other Serious 30 Male 9/12/2007 Physician France
Primary
Concomitant
Oedema Peripheral 7/6/2007 56 Male 179 lb 10/12/2007 United States
Primary
Concomitant
Renal Cell Carcinoma Other Serious Male 2/11/2008 Consumer United States
Primary
Concomitant
Renal Cell Carcinoma Other Serious Male 2/15/2008 Consumer United States
Primary
Concomitant
Proteinuria Other Serious 42 Female 3/11/2008 Other Health Professional United States
Primary
Secondary
Proteinuria Other Serious 56 Male 3/11/2008 Other Health Professional United States
Primary
Secondary
Electrocardiogram St Segment Elevation Hospitalization 8/20/2007 70 Male 223 lb 4/14/2008 Consumer United States
Primary
Secondary
Renal Failure Hospitalization 11/7/2007 74 Male 196 lb 4/16/2008 Physician United States
Primary
Secondary
Concomitant
Proteinuria Other Serious 42 Female 7/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Proteinuria Other Serious 56 Male 7/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 6/25/2008 Male 207 lb 9/25/2008 Physician United States
Primary
Secondary
Concomitant
Electrocardiogram St Segment Elevation Hospitalization 8/20/2007 70 Male 223 lb 9/30/2008 Consumer United States
Primary
Secondary
Vomiting Other Serious 5/10/2007 73 Female 234 lb 11/11/2008 Consumer United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2006 48 Male 154 lb 11/18/2008 Physician Switzerland
Primary
Secondary
Tooth Extraction Other Serious 1/1/2006 Male 11/18/2008 Other Health Professional Switzerland
Primary
Secondary
Osteonecrosis Other Serious 1/1/2006 50 Male 1543 lb 11/26/2008 Physician Switzerland
Primary
Secondary
Gait Disturbance Other Serious Female 12/23/2008 Physician United States
Primary
Secondary
Hepatic Function Abnormal Other Serious 12/1/2008 80 Male 1/12/2009 Physician Japan
Primary
Concomitant
Gait Disturbance Other Serious Female 238 lb 1/12/2009 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2006 50 Male 154 lb 1/7/2009 Physician Switzerland
Primary
Secondary
Osteonecrosis Other Serious 1/1/2006 48 Male 154 lb 1/20/2009 Physician Switzerland
Primary
Secondary
Hypertension Other Serious 11/17/2008 83 Male 126 lb 1/23/2009 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2007 Male 1/28/2009 Other Health Professional Switzerland
Primary
Secondary
Condition Aggravated Other Serious 1/1/2007 49 Male 154 lb 1/30/2009 Physician Switzerland
Primary
Secondary
Renal Impairment Hospitalization 9/19/2008 70 Male 143 lb 2/23/2009 Physician Japan
Primary
Concomitant
Alopecia Female 3/23/2009 Other Health Professional United States
Primary
Concomitant
Hypertension Other Serious 11/17/2008 83 Male 126 lb 3/26/2009 Physician Japan
Primary
Concomitant
Osteitis Other Serious 4/1/2009 Physician Sweden
Primary
Concomitant
Withdrawal Syndrome Other Serious 11/20/2008 89 Female 106 lb 5/13/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/30/2008 67 Male 150 lb 5/26/2009 Physician Japan
Primary
Concomitant
Alopecia Female 6/1/2009 Other Health Professional United States
Primary
Concomitant
Hypertension Other Serious 11/17/2008 83 Male 126 lb 6/24/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/16/2008 54 Male 110 lb 7/2/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/30/2008 67 Male 150 lb 7/2/2009 Physician Japan
Primary
Concomitant
Rash Macular 2/1/2009 55 Male 8/10/2009 Consumer United States
Primary
Concomitant
Skin Exfoliation Other Serious 2/11/2009 71 Male 143 lb 8/31/2009 Physician Japan
Primary
Secondary
Concomitant
Angioedema Life Threatening 7/1/2008 63 Male 209 lb 9/9/2009 Physician Denmark
Primary
Secondary
Concomitant
Troponin T Increased Other Serious Male 10/22/2009 Physician Austria
Primary
Secondary
Concomitant
Temperature Regulation Disorder Hospitalization 6/6/2006 66 Male 216 lb 11/16/2009 Physician United States
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 1/1/2008 85 Female 12/17/2009 Consumer France
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/11/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/18/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/26/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/2/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/16/2008 54 Male 110 lb 3/3/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/11/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/18/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/30/2010 Physician United States
Primary
Concomitant
Skin Exfoliation Other Serious 2/11/2009 71 Male 143 lb 4/12/2010 Physician Japan
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/19/2009 62 Male 132 lb 4/22/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Death 4/13/2010 Male 4/29/2010 Physician Japan
Primary
Concomitant
Lymphoma Other Serious 11/16/2009 47 Female 152 lb 5/4/2010 Physician Denmark
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/6/2008 54 Male 110 lb 5/11/2010 Physician Japan
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/19/2009 62 Male 132 lb 5/26/2010 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 6/6/2008 54 Male 110 lb 6/3/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 6/6/2008 54 Male 110 lb 6/3/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar Erythema Disability 6/12/2008 51 Male 203 lb 6/3/2010 Physician Japan
Primary
Concomitant
Rash Death 9/1/2009 55 Male 6/15/2010 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening 5/2/2010 68 Male 7/15/2010 Physician Japan
Primary
Secondary
Rash Other Serious 6/30/2009 63 Male 126 lb 7/26/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 2/1/2010 Female 8/2/2010 Consumer United States
Primary
Concomitant
Skin Exfoliation Other Serious 5/6/2010 57 Male 179 lb 8/9/2010 Physician Japan
Primary
Concomitant
Palmar Erythema Death 6/12/2008 51 Male 159 lb 8/24/2010 Physician Japan
Primary
Secondary
Concomitant
Splenic Infarction Hospitalization 11/21/2009 75 Male 137 lb 9/1/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization Male 110 lb 9/7/2010 Physician Japan
Primary
Concomitant
Thyroiditis Other Serious 4/1/2010 53 Female 9/27/2010 Physician Germany
Primary
Secondary
Concomitant
Thyroiditis Other Serious 4/1/2010 53 Female 9/28/2010 Physician Germany
Primary
Secondary
Concomitant
Thyroiditis Other Serious 4/1/2010 53 Female 9/30/2010 Physician Germany
Primary
Secondary
Concomitant
Rash Other Serious 6/30/2009 63 Male 126 lb 9/30/2010 Physician Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization Male 110 lb 10/20/2010 Physician Japan
Primary
Concomitant
Pollakiuria Male 11/15/2010 Consumer United States
Primary
Concomitant
Stomatitis Other Serious 6/1/2010 Female 99 lb 11/30/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Death Male 110 lb 12/16/2010 Physician Japan
Primary
Concomitant
Thrombosis Life Threatening Male 12/23/2010 Other Health Professional United States
Primary
Secondary
Type 2 Diabetes Mellitus Hospitalization 1/19/2009 61 Male 132 lb 12/27/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 5/21/2009 54 Male 126 lb 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 5/6/2010 57 Male 179 lb 12/29/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 6/1/2010 Female 99 lb 12/30/2010 Physician Japan
Primary
Concomitant
Fatigue Male 1/13/2011 Pharmacist United States
Primary
Concomitant
Kidney Rupture Hospitalization 5/2/2010 68 Male 126 lb 1/28/2011 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/25/2009 52 Male 112 lb 2/3/2011 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 12/26/2010 74 Female 104 lb 3/9/2011 Physician Japan
Primary
Concomitant
Cerebellar Haemorrhage Other Serious 6/1/2010 69 Male 115 lb 3/24/2011 Physician Japan
Primary
Concomitant
Erythema Hospitalization 12/22/2010 68 Female 117 lb 4/5/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 5/6/2010 57 Male 179 lb 4/5/2011 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 11/21/2009 75 Male 136 lb 4/13/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 11/21/2009 75 Male 136 lb 4/19/2011 Physician Japan
Primary
Secondary
Concomitant
Splenic Infarction Death 11/21/2009 75 Male 136 lb 4/25/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Proteinuria Other Serious 12/1/2009 52 Male 194 lb 5/10/2011 Physician Japan
Primary
Concomitant
Nephrotic Syndrome Other Serious 12/1/2009 52 Male 194 lb 5/18/2011 Physician Japan
Primary
Concomitant
Alopecia Hospitalization 6/12/2008 51 Male 203 lb 5/18/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Disability 3/25/2009 52 Male 112 lb 5/26/2011 Physician Japan
Primary
Concomitant
Fatigue Male 6/1/2011 Pharmacist United States
Primary
Concomitant
Haematemesis Other Serious 5/3/2010 57 Male 179 lb 6/2/2011 Physician Japan
Primary
Concomitant
Rash Generalised Death 5/3/2010 57 Male 179 lb 6/6/2011 Physician Japan
Primary
Concomitant
Piriformis Syndrome Other Serious Male 6/10/2011 Lawyer United States
Primary
Concomitant
Bone Pain Other Serious Male 6/14/2011 Consumer United States
Primary
Concomitant
Muscle Spasms Other Serious Male 6/16/2011 Consumer United States
Primary
Concomitant
Mental Status Changes Other Serious Male 6/24/2011 Consumer United States
Primary
Concomitant
Exposed Bone In Jaw Death Male 6/28/2011 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious Male 6/29/2011 Lawyer United States
Primary
Concomitant
Osteoarthritis Other Serious Male 7/12/2011 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 60 Female 101 lb 7/12/2011 United States
Primary
Concomitant
Constipation Other Serious Male 7/14/2011 Lawyer United States
Primary
Concomitant
Metaplasia Other Serious Male 7/19/2011 Consumer United States
Primary
Concomitant
Constipation Death Male 7/21/2011 Physician United States
Primary
Concomitant
Papilloedema Disability 1/15/2011 57 Female 119 lb 7/31/2011 Physician Germany
Primary
Concomitant
Denture Wearer Death Male 8/5/2011 Consumer United States
Primary
Concomitant
Fall Death Male 8/8/2011 Physician United States
Primary
Concomitant
Dizziness Other Serious 6/2/2011 69 Female 123 lb 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Hypertension Disability Male 177 lb 8/25/2011 Lawyer United States
Primary
Concomitant
Lipid Metabolism Disorder Disability 7/9/2009 42 Female 8/30/2011 Lawyer United States
Primary
Concomitant
Tachycardia Other Serious 7/9/2009 42 Female 8/31/2011 Lawyer United States
Primary
Concomitant
Haemoptysis Other Serious 40 Male 8/31/2011 Other Health Professional Norway
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 48 Female 9/9/2011 Physician France
Primary
Secondary
Rash Generalised Other Serious 5/3/2010 57 Male 179 lb 9/16/2011 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Infection Disability 7/9/2009 42 Female 9/27/2011 Physician United States
Primary
Concomitant
Impaired Gastric Emptying Disability 7/9/2009 42 Female 10/3/2011 Physician United States
Primary
Concomitant
Quality Of Life Decreased Disability Male 177 lb 10/6/2011 Physician United States
Primary
Concomitant
Nasal Congestion Other Serious 7/9/2009 42 Female 10/7/2011 Lawyer United States
Primary
Concomitant
Rhinorrhoea Hospitalization 7/9/2009 42 Female 10/20/2011 Physician United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome 2/14/2011 61 Female 10/21/2011 Consumer United States
Primary
Concomitant
Jaundice Hospitalization 10/1/2011 66 Female 10/26/2011 Physician Germany
Primary
Concomitant
Syncope Hospitalization 1/1/2011 54 Female 10/27/2011 United States
Primary
Concomitant
Blood Pressure Increased 62 Male 11/9/2011 Consumer United States
Primary
Concomitant
Haematemesis Disability Male 177 lb 11/16/2011 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious Male 177 lb 11/21/2011 Physician United States
Primary
Concomitant
Nasal Congestion Hospitalization 7/9/2009 42 Female 11/23/2011 Lawyer United States
Primary
Concomitant
Renal Cell Carcinoma Death 4/26/2010 55 Male 11/28/2011 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 4/26/2010 55 Male 11/30/2011 Physician Japan
Primary
Concomitant
Death Death 11/25/2011 68 Male 12/1/2011 Consumer United States
Primary
Concomitant
Tongue Discolouration Other Serious 11/1/2011 64 Female 12/2/2011 Other Health Professional United States
Primary
Concomitant
Disease Progression Other Serious 1/1/2009 73 Female 108 lb 12/22/2011 Physician Germany
Primary
Secondary
Swollen Tongue Other Serious 11/1/2011 64 Female 12/26/2011 Physician United States
Primary
Concomitant
Rhinorrhoea Hospitalization 7/9/2009 42 Female 1/1/2012 Lawyer United States
Primary
Concomitant
Neoplasm Malignant Hospitalization 1/1/2009 73 Female 108 lb 1/4/2012 Consumer United States
Primary
Secondary
Concomitant
Carcinoma In Situ Death 7/9/2009 42 Female 1/6/2012 Lawyer United States
Primary
Concomitant
Joint Swelling Other Serious Male 177 lb 1/25/2012 Lawyer United States
Primary
Concomitant
Pneumonia Other Serious Male 177 lb 2/3/2012 Physician United States
Primary
Concomitant
Haemoptysis Hospitalization 10/2/2011 73 Female 146 lb 2/6/2012 Physician Germany
Primary
Concomitant
Joint Swelling Other Serious Male 177 lb 2/10/2012 Physician United States
Primary
Concomitant
Femur Fracture Hospitalization Male 177 lb 2/16/2012 Lawyer United States
Primary
Concomitant
Arteriosclerosis Hospitalization Male 177 lb 3/7/2012 Physician United States
Primary
Concomitant
Hypothyroidism Hospitalization Male 177 lb 3/29/2012 Lawyer United States
Primary
Concomitant

Drug Data