Nexavar combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Incontinence Other Serious 3/10/2006 Female 110 lb 3/15/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/19/2006 83 Female 112 lb 5/23/2006 Consumer United States
Primary
Concomitant
Nausea 1/1/2006 68 Male 4/24/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2006 83 Female 112 lb 6/21/2006 United States
Primary
Concomitant
Urinary Incontinence 3/10/2006 Female 110 lb 7/12/2006 United States
Primary
Concomitant
Vomiting 1/1/2006 68 Male 7/12/2006 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 2/1/2007 63 Male 4/2/2007 Physician United States
Primary
Concomitant
Vascular Pseudoaneurysm Hospitalization 2/1/2007 63 Male 185 lb 4/23/2007 Physician United States
Primary
Concomitant
Vascular Pseudoaneurysm Hospitalization 2/1/2007 63 Male 185 lb 5/10/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 11/1/2006 52 Male 320 lb 1/23/2007 Physician United States
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/1/2007 60 Female 7/27/2007 United States
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/1/2007 60 Female 8/2/2007 United States
Primary
Concomitant
Skin Cancer Other Serious 7/1/2007 73 Male 8/2/2007 United States
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/1/2007 60 Female 8/10/2007 United States
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/1/2007 60 Female 8/14/2007 United States
Primary
Concomitant
Vomiting 11/1/2007 58 Male 11/19/2007 Consumer United States
Primary
Concomitant
Skin Cancer Other Serious 7/1/2007 73 Male 2/7/2008 United States
Primary
Concomitant
Vomiting Hospitalization 4/3/2008 85 Male 132 lb 7/14/2008 Physician Germany
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 2/1/2008 60 Male 269 lb 1/16/2009 Other Health Professional United States
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 2/1/2008 60 Male 269 lb 1/19/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 10/10/2008 60 Male 183 lb 1/23/2009 Netherlands
Primary
Concomitant
Weight Decreased Other Serious 10/10/2008 60 Male 183 lb 2/2/2009 Netherlands
Primary
Concomitant
Weight Decreased Other Serious 10/10/2008 60 Male 183 lb 2/6/2009 Netherlands
Primary
Concomitant
Hepatic Failure Other Serious 9/24/2007 65 Male 262 lb 6/18/2009 United States
Primary
Concomitant
Hepatic Failure Other Serious 9/24/2007 65 Male 262 lb 6/24/2009 United States
Primary
Concomitant
Hepatic Function Abnormal Other Serious 6/1/2009 64 Male 6/25/2009 Netherlands
Primary
Concomitant
Nausea Other Serious 76 Male 170 lb 6/29/2009 Consumer Canada
Primary
Concomitant
Neoplasm Progression Other Serious 1/1/2009 64 Male 7/8/2009 Netherlands
Primary
Concomitant
Renal Failure Acute Death 7/7/2009 76 Male 7/28/2009 Physician Germany
Primary
Concomitant
Renal Failure Acute Life Threatening 7/7/2009 77 Male 7/29/2009 Physician Germany
Primary
Concomitant
Nausea Other Serious 2/3/2009 76 Male 170 lb 9/18/2009 Consumer Canada
Primary
Concomitant
Thrombocytopenia Other Serious 5/21/2009 71 Male 137 lb 9/29/2009 Korea, Republic Of
Primary
Concomitant
Rectal Haemorrhage Other Serious 11/2/2009 74 Male 11/4/2009 Netherlands
Primary
Concomitant
Rectal Haemorrhage Other Serious 11/2/2009 74 Male 11/6/2009 Netherlands
Primary
Concomitant
Rectal Haemorrhage Other Serious 11/2/2009 74 Male 11/10/2009 Netherlands
Primary
Concomitant
Renal Impairment Life Threatening 8/26/2009 71 Male 128 lb 11/24/2009 Physician Japan
Primary
Concomitant
Productive Cough Hospitalization 10/1/2007 62 Male 12/17/2009 Consumer France
Primary
Concomitant
Vaginal Haemorrhage Other Serious 10/1/2009 72 Female 3/25/2010 United States
Primary
Concomitant
Streptococcal Infection Hospitalization Male 4/12/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 5/21/2009 71 Male 143 lb 4/26/2010 Korea, Republic Of
Primary
Concomitant
Streptococcal Infection Hospitalization Male 270 lb 4/29/2010 Pharmacist United States
Primary
Concomitant
Lactose Intolerance Hospitalization 3/1/2009 80 Female 108 lb 6/9/2010 Germany
Primary
Concomitant
Malaise Other Serious 5/17/2010 54 Male 6/30/2010 Ireland
Primary
Concomitant
Malaise Hospitalization 5/17/2010 54 Male 7/28/2010 Ireland
Primary
Concomitant
Malaise Hospitalization 5/17/2010 54 Male 7/29/2010 Ireland
Primary
Concomitant
Lactose Intolerance Other Serious 3/1/2009 80 Female 108 lb 8/9/2010 Germany
Primary
Concomitant
Malaise Hospitalization 5/17/2010 54 Male 8/17/2010 Ireland
Primary
Concomitant
Malaise Hospitalization 5/17/2010 54 Male 8/18/2010 Ireland
Primary
Concomitant
Somnolence Other Serious 1/4/2010 71 Male 8/27/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/4/2010 71 Male 9/3/2010 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 7/29/2010 70 Male 176 lb 9/15/2010 Physician Germany
Primary
Concomitant
Open Wound Hospitalization 9/9/2010 67 Male 128 lb 9/16/2010 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 7/29/2010 70 Male 176 lb 9/20/2010 Physician Germany
Primary
Concomitant
Infection Hospitalization 3/25/2010 58 Female 9/20/2010 Sweden
Primary
Concomitant
Somnolence Other Serious 1/4/2010 71 Male 9/20/2010 Physician United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 8/26/2009 71 Male 128 lb 9/23/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 8/21/2010 71 Male 9/27/2010 Physician Spain
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 7/29/2010 70 Male 176 lb 9/29/2010 Physician Germany
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 10/1/2010 53 Female 10/21/2010 Physician Romania
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 6/29/2010 70 Male 176 lb 10/21/2010 Physician Germany
Primary
Concomitant
Hepatic Function Abnormal Death 7/5/2010 57 Male 11/1/2010 Portugal
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 10/1/2010 53 Female 11/1/2010 Physician Romania
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/17/2010 77 Male 134 lb 11/1/2010 Physician Japan
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/17/2010 77 Male 134 lb 11/9/2010 Physician Japan
Primary
Concomitant
Jaundice Death 7/5/2010 57 Male 11/10/2010 Portugal
Primary
Concomitant
Fatigue Hospitalization 10/26/2010 63 Female 143 lb 11/10/2010 Physician Sweden
Primary
Concomitant
Pulmonary Embolism Other Serious 10/27/2010 60 Male 11/23/2010 Venezuela
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 6/29/2010 70 Male 176 lb 12/27/2010 Physician Germany
Primary
Concomitant
Encephalopathy Death 1/4/2010 71 Male 1/14/2011 Physician United States
Primary
Concomitant
Ammonia Increased Hospitalization 11/9/2010 59 Male 235 lb 1/28/2011 Physician United States
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 9/9/2010 67 Male 128 lb 1/28/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Death 11/30/2010 66 Male 150 lb 1/28/2011 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 7/8/2010 70 Male 2/13/2011 Physician Spain
Primary
Concomitant
Arterial Thrombosis Limb Life Threatening 8/26/2009 71 Male 128 lb 2/14/2011 Physician Japan
Primary
Secondary
Concomitant
Open Wound Hospitalization 9/9/2010 67 Male 128 lb 2/23/2011 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Death 9/9/2010 67 Male 128 lb 2/24/2011 Physician Japan
Primary
Concomitant
Oesophageal Varices Haemorrhage Death 8/9/2010 69 Male 114 lb 3/9/2011 Physician New Zealand
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 11/30/2010 66 Male 154 lb 3/16/2011 Physician United States
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 8/9/2010 69 Male 114 lb 3/19/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 8/9/2010 69 Male 114 lb 3/23/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 9/20/2010 81 Male 112 lb 3/30/2011 Physician Japan
Primary
Concomitant
Ascites Death 11/13/2010 66 Male 154 lb 4/6/2011 Physician United States
Primary
Concomitant
Sepsis Death 3/27/2011 30 Male 4/7/2011 Physician Philippines
Primary
Concomitant
Anosmia Hospitalization 6/29/2010 70 Male 176 lb 4/7/2011 Physician Germany
Primary
Concomitant
Ascites Hospitalization 12/28/2010 67 Female 137 lb 4/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 9/20/2010 81 Male 112 lb 4/19/2011 Physician Japan
Primary
Concomitant
Necrotising Fasciitis Hospitalization 10/5/2009 51 Female 209 lb 4/15/2011 Consumer Germany
Primary
Concomitant
Hepatic Failure Other Serious 2/8/2011 69 Male 122 lb 5/9/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Chest Pain Hospitalization 6/14/2010 57 Female 272 lb 5/11/2011 Consumer United States
Primary
Concomitant
Vertigo Other Serious 10/25/2010 73 Male 5/11/2011 Consumer Germany
Primary
Concomitant
Pain In Extremity Death 9/17/2010 59 Male 5/11/2011 Physician Australia
Primary
Concomitant
Haematemesis Life Threatening 8/9/2010 69 Male 114 lb 5/27/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Pain In Jaw 53 Female 117 lb 5/19/2011 Pharmacist United States
Primary
Concomitant
Death Death 3/25/2010 58 Female 6/3/2011 Consumer Sweden
Primary
Concomitant
Loss Of Consciousness Hospitalization 5/1/2011 83 Female 6/13/2011 Consumer United States
Primary
Concomitant
Fatigue Other Serious 57 Male 7/8/2011 Pharmacist United States
Primary
Concomitant
Fatigue Hospitalization 10/26/2010 63 Female 143 lb 7/14/2011 Consumer Sweden
Primary
Concomitant
Fatigue Hospitalization 1/1/2011 50 Male 152 lb 7/15/2011 Other Health Professional United States
Primary
Concomitant
Jaundice Death 3/1/2011 69 Female 7/23/2011 Physician Japan
Primary
Concomitant
Atrial Fibrillation Other Serious 1/4/2010 71 Male 8/5/2011 Consumer United States
Primary
Secondary
Concomitant
Hyperkeratosis Palmaris And Plantaris Hospitalization 1/1/2011 50 Male 152 lb 8/5/2011 Physician United States
Primary
Concomitant
Portal Vein Thrombosis Death 7/20/2011 72 Male 8/18/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 7/22/2011 72 Male 121 lb 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Ascites Death 7/20/2011 72 Male 174 lb 8/30/2011 Physician Japan
Primary
Concomitant
Abdominal Pain Disability 6/1/2011 54 Male 192 lb 9/1/2011 Physician Brazil
Primary
Concomitant
Hepatic Failure Other Serious 8/15/2011 38 Male 9/6/2011 Consumer United States
Primary
Concomitant
Ascites Hospitalization 6/21/2011 66 Male 9/7/2011 Consumer United States
Primary
Concomitant
Nausea 1/1/2011 69 Male 9/27/2011 Consumer United States
Primary
Concomitant
Decreased Appetite Disability 1/1/2011 54 Male 192 lb 9/29/2011 Consumer Brazil
Primary
Concomitant
Dyspnoea Other Serious 4/1/2011 54 Male 10/1/2011 Consumer United States
Primary
Concomitant
Cerebral Haemorrhage Death 5/1/2011 83 Female 10/5/2011 Consumer United States
Primary
Concomitant
Fall Hospitalization 6/20/2011 66 Male 10/12/2011 Physician United States
Primary
Concomitant
Somnolence Life Threatening 1/4/2010 71 Male 10/20/2011 Physician United States
Primary
Secondary
Concomitant
Encephalopathy Disability 1/1/2011 54 Male 192 lb 10/24/2011 Physician Brazil
Primary
Concomitant
Fatigue 66 Female 10/27/2011 Consumer United States
Primary
Concomitant
Pain Of Skin Other Serious 6/1/2011 38 Female 10/31/2011 Physician United States
Primary
Concomitant
Chromaturia Other Serious 11/6/2010 59 Male 235 lb 10/31/2011 Other Health Professional United States
Primary
Concomitant
Fatigue Other Serious 57 Male 11/10/2011 Consumer United States
Primary
Concomitant
Diarrhoea 10/1/2011 66 Female 11/15/2011 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 8/2/2011 64 Male 154 lb 11/15/2011 Physician Hungary
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 59 Male 11/21/2011 Pharmacist United States
Primary
Concomitant
Fatigue Other Serious 57 Male 12/2/2011 Pharmacist United States
Primary
Concomitant
Fall Hospitalization 10/26/2010 63 Female 143 lb 12/22/2011 Physician Sweden
Primary
Concomitant
Diarrhoea Hospitalization 3/26/2009 70 Male 176 lb 1/3/2012 Consumer Germany
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Death 7/9/2011 59 Female 1/18/2012 Consumer United States
Primary
Concomitant
Blood Sodium Decreased Hospitalization 59 Male 1/24/2012 Pharmacist United States
Primary
Concomitant
Fatigue Hospitalization 10/26/2010 63 Female 143 lb 1/31/2012 Physician Sweden
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 3/16/2010 57 Male 2/6/2012 Consumer United States
Primary
Concomitant
Confusional State Hospitalization 11/26/2011 65 Male 209 lb 2/23/2012 Consumer United Kingdom
Primary
Concomitant
Fatigue Death 10/1/2011 66 Female 3/2/2012 Pharmacist United States
Primary
Concomitant
Confusional State Hospitalization 11/24/2011 Male 3/8/2012 Other Health Professional United Kingdom
Primary
Concomitant
Fatigue Hospitalization 59 Male 180 lb 3/8/2012 Pharmacist United States
Primary
Concomitant
Confusional State Hospitalization 11/26/2011 65 Male 209 lb 3/19/2012 Consumer United Kingdom
Primary
Concomitant
Fatigue Hospitalization 4/1/2012 59 Male 4/5/2012 Consumer United States
Primary
Concomitant
Pulmonary Embolism Death 10/27/2010 60 Male 4/13/2012 Consumer Venezuela
Primary
Concomitant
Pain In Jaw 9/21/2011 53 Female 117 lb 5/30/2012 Other Health Professional United States
Primary
Concomitant
Diarrhoea Death 10/1/2011 66 Female 5/30/2012 Pharmacist United States
Primary
Concomitant
Dehydration Other Serious 4/1/2012 72 Male 6/12/2012 Consumer United States
Primary
Concomitant
Ammonia Increased Hospitalization 4/1/2012 59 Male 172 lb 6/25/2012 Physician United States
Primary
Concomitant
Syncope Other Serious 2/1/2012 69 Female 132 lb 6/25/2012 Consumer Brazil
Primary
Concomitant
Ascites Hospitalization 12/6/2010 79 Male 126 lb 7/13/2012 Physician France
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 6/29/2010 70 Male 176 lb 7/23/2012 Consumer Germany
Primary
Concomitant
Hepatic Encephalopathy Other Serious 3/28/2010 76 Male 141 lb 7/24/2012 Physician Colombia
Primary
Concomitant
Hepatic Neoplasm Malignant Death 2/28/2012 72 Female 7/30/2012 Other Health Professional United States
Primary
Concomitant
Nephrotic Syndrome Hospitalization 4/30/2012 65 Male 181 lb 8/3/2012 Physician Chile
Primary
Secondary
Concomitant
Erythema Hospitalization 1/26/2011 67 Male 137 lb 8/6/2012 Other Health Professional Brazil
Primary
Concomitant
Oedema Hospitalization 1/20/2011 67 Male 137 lb 8/7/2012 Physician Brazil
Primary
Concomitant
Hepatic Failure Death 3/19/2012 65 Male 161 lb 8/8/2012 Physician Japan
Primary
Concomitant
Ascites Hospitalization 11/30/2010 66 Male 154 lb 8/15/2012 Other Health Professional United States
Primary
Concomitant
Malnutrition Death 6/3/2010 78 Female 128 lb 8/24/2012 Physician Czech Republic
Primary
Concomitant

Drug Data