Nexavar combined with Pursennid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Shock Haemorrhagic Death 7/11/2008 60 Male 198 lb 8/13/2008 Physician Japan
Primary
Concomitant
Hypertension 8/21/2008 74 Male 123 lb 9/22/2008 Physician Japan
Primary
Concomitant
Renal Failure Death 5/28/2008 76 Male 132 lb 9/24/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/2/2008 69 Female 110 lb 9/30/2008 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/9/2008 52 Male 143 lb 9/30/2008 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/11/2008 Female 10/7/2008 Physician Japan
Primary
Concomitant
Shock Haemorrhagic Death 7/11/2008 60 Male 198 lb 10/9/2008 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/19/2008 73 Male 179 lb 10/22/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/2/2008 69 Female 110 lb 10/24/2008 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/22/2008 80 Male 134 lb 11/7/2008 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/9/2008 52 Male 143 lb 11/14/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/2/2008 69 Female 110 lb 11/18/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/2/2008 69 Female 110 lb 12/1/2008 Physician Japan
Primary
Concomitant
Sudden Death Death 10/20/2008 75 Male 12/1/2008 Physician Japan
Primary
Concomitant
Hypertension Death 9/5/2008 72 Female 139 lb 12/5/2008 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 5/6/2008 65 Male 183 lb 12/18/2008 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 9/11/2008 61 Female 115 lb 12/29/2008 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/22/2008 80 Male 134 lb 1/22/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 10/30/2008 59 Male 150 lb 2/3/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/22/2008 80 Male 134 lb 2/9/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 8/27/2008 73 Female 99 lb 2/17/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Other Serious 8/29/2008 82 Female 3/5/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/22/2008 80 Male 134 lb 3/12/2009 Physician Japan
Primary
Concomitant
Rash Other Serious 11/21/2008 62 Male 148 lb 3/20/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 7/26/2008 67 Male 150 lb 3/30/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 8/27/2008 73 Female 99 lb 4/9/2009 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Life Threatening 4/11/2009 83 Female 108 lb 5/19/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 7/24/2008 77 Male 112 lb 6/4/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 7/24/2008 77 Male 112 lb 6/10/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 7/24/2008 77 Male 112 lb 6/16/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/22/2008 80 Male 134 lb 7/7/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 5/6/2008 65 Male 183 lb 7/10/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 4/26/2009 88 Male 123 lb 7/17/2009 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Disability 9/5/2008 72 Female 139 lb 7/23/2009 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 7/5/2009 61 Male 7/27/2009 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Other Serious 7/7/2009 58 Male 7/30/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 62 Male 121 lb 7/30/2009 Physician Japan
Primary
Concomitant
Rash Death 10/7/2008 84 Male 117 lb 8/6/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 62 Male 121 lb 8/14/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 6/26/2009 58 Male 143 lb 8/20/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/8/2009 55 Female 112 lb 8/21/2009 Physician Japan
Primary
Concomitant
Nausea Death 7/30/2009 80 Male 97 lb 8/27/2009 Physician Japan
Primary
Concomitant
Renal Failure Life Threatening 7/9/2009 70 Male 121 lb 9/3/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 4/26/2009 88 Male 123 lb 9/3/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/22/2008 80 Male 134 lb 9/17/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 12/22/2008 73 Male 134 lb 10/14/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/5/2009 61 Male 10/14/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 8/17/2009 82 Male 99 lb 10/16/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/1/2009 23 Male 130 lb 10/26/2009 Physician Japan
Primary
Concomitant
Nausea Life Threatening 7/30/2009 80 Male 97 lb 10/28/2009 Physician Japan
Primary
Concomitant
Septic Shock Hospitalization 7/17/2009 70 Female 108 lb 11/10/2009 Physician Japan
Primary
Concomitant
Depression Hospitalization 7/17/2009 70 Female 108 lb 11/12/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Other Serious 7/26/2008 67 Male 150 lb 11/13/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/22/2009 75 Male 11/20/2009 Physician Japan
Primary
Concomitant
Cholangitis Suppurative Death 10/7/2009 71 Female 108 lb 12/3/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 62 Male 121 lb 12/3/2009 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Death 10/9/2009 88 Male 130 lb 12/14/2009 Physician Japan
Primary
Concomitant
Tremor Hospitalization 3/14/2009 78 Male 137 lb 12/18/2009 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/1/2009 67 Female 123 lb 12/18/2009 Physician Japan
Primary
Concomitant
Rash Generalised Hospitalization 7/14/2008 81 Female 93 lb 12/28/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/19/2009 72 Male 165 lb 12/28/2009 Physician Japan
Primary
Concomitant
Erythema Multiforme Other Serious 7/31/2009 68 Female 99 lb 1/5/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Death 10/9/2009 88 Male 130 lb 1/6/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/22/2009 75 Male 1/6/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/22/2009 75 Male 1/7/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 9/4/2009 66 Male 128 lb 1/15/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Death 11/21/2009 71 Male 1/25/2010 Physician Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 9/9/2009 59 Female 134 lb 1/28/2010 Physician Japan
Primary
Concomitant
Thyroiditis Hospitalization 12/11/2009 74 Male 130 lb 2/1/2010 Physician Japan
Primary
Concomitant
Liver Carcinoma Ruptured Hospitalization 12/10/2009 74 Male 2/4/2010 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 12/1/2009 64 Male 2/9/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 4/26/2009 88 Male 123 lb 2/12/2010 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 12/25/2009 64 Male 2/16/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 4/26/2009 88 Male 123 lb 2/17/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 62 Male 121 lb 2/17/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 62 Male 121 lb 2/23/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/22/2009 75 Male 3/1/2010 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 9/1/2009 23 Male 130 lb 3/2/2010 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 7/9/2009 70 Male 121 lb 3/8/2010 Physician Japan
Primary
Concomitant
Depression Hospitalization 8/31/2009 71 Female 108 lb 3/9/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/2/2009 70 Male 132 lb 3/19/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/19/2009 72 Male 165 lb 4/12/2010 Physician Japan
Primary
Concomitant
Rash Life Threatening 9/21/2009 71 Male 168 lb 4/15/2010 Physician Japan
Primary
Concomitant
Rash Generalised Hospitalization 7/14/2008 81 Female 93 lb 4/16/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased 1/8/2009 55 Female 112 lb 4/16/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2009 66 Male 119 lb 4/29/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 62 Male 121 lb 4/29/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/1/2009 76 Male 132 lb 5/13/2010 Physician Japan
Primary
Concomitant
Hypertension Other Serious 8/29/2008 82 Female 5/17/2010 Physician Japan
Primary
Concomitant
Hypertension Other Serious 8/29/2008 82 Female 5/18/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 8/31/2009 71 Male 168 lb 5/24/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2009 66 Male 119 lb 6/1/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 8/11/2009 58 Male 170 lb 6/1/2010 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Stage Iii Life Threatening 4/11/2009 83 Female 108 lb 6/1/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/31/2009 67 Female 123 lb 6/9/2010 Physician Japan
Primary
Concomitant
Rash Death 9/1/2009 55 Male 6/15/2010 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 12/26/2009 81 Male 117 lb 6/16/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/22/2008 80 Male 134 lb 6/29/2010 Physician Japan
Primary
Concomitant
Rash Death 9/1/2009 55 Male 126 lb 7/7/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 6/22/2010 78 Female 117 lb 7/16/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Death 6/17/2010 36 Male 150 lb 7/26/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Death 6/17/2010 36 Male 150 lb 8/3/2010 Physician Japan
Primary
Concomitant
Skin Exfoliation Other Serious 5/6/2010 57 Male 179 lb 8/9/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 11/1/2009 57 Male 130 lb 8/10/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/1/2009 76 Male 132 lb 8/11/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 4/26/2009 88 Male 123 lb 8/11/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 6/18/2010 78 Female 117 lb 8/20/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Death 5/28/2010 80 Male 99 lb 8/26/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/10/2010 80 Male 126 lb 8/26/2010 Physician Japan
Primary
Concomitant
Sepsis Death 11/30/2009 81 Male 9/1/2010 Physician Japan
Primary
Concomitant
Liver Carcinoma Ruptured Hospitalization 8/16/2010 86 Female 104 lb 9/8/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 8/31/2009 71 Male 168 lb 9/15/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/4/2010 86 Female 104 lb 9/16/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 9/14/2010 77 Male 104 lb 10/6/2010 Japan
Primary
Concomitant
Rash Other Serious 8/3/2009 69 Female 121 lb 10/8/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/10/2010 80 Male 126 lb 10/11/2010 Physician Japan
Primary
Concomitant
Hypertension Hospitalization 9/8/2010 81 Male 115 lb 10/22/2010 Physician Japan
Primary
Concomitant
Infection Other Serious 5/27/2010 64 Male 247 lb 11/9/2010 Physician Japan
Primary
Secondary
Concomitant
Tinnitus Other Serious 4/7/2010 67 Male 117 lb 11/17/2010 Physician Japan
Primary
Concomitant
Tumour Rupture Hospitalization 7/4/2010 86 Female 104 lb 12/21/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/14/2009 77 Male 137 lb 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 5/21/2009 54 Male 126 lb 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 5/6/2010 57 Male 179 lb 12/29/2010 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Other Serious 5/19/2009 71 Male 163 lb 12/29/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 11/7/2010 61 Female 95 lb 2/11/2011 Physician Japan
Primary
Concomitant
Hypertension Other Serious 2/6/2009 70 Male 140 lb 2/25/2011 Physician Japan
Primary
Concomitant
Dehydration Other Serious 11/7/2010 61 Female 95 lb 2/24/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 2/6/2009 70 Male 140 lb 3/8/2011 Physician Japan
Primary
Concomitant
Deafness Other Serious 4/7/2010 67 Male 117 lb 3/11/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Carcinoma Ruptured Death 12/10/2009 74 Male 4/1/2011 Physician Japan
Primary
Concomitant
Pyrexia Death 9/29/2010 66 Male 126 lb 4/4/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 5/6/2010 57 Male 179 lb 4/5/2011 Physician Japan
Primary
Concomitant
Hypoglycaemia Other Serious 4/7/2010 67 Male 117 lb 4/18/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/1/2009 23 Male 130 lb 4/19/2011 Other Health Professional Japan
Primary
Concomitant
Sudden Death Death 1/5/2011 60 Male 141 lb 5/17/2011 Physician Japan
Primary
Secondary
Concomitant
Sudden Death Death 1/5/2011 60 Male 141 lb 5/21/2011 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 8/29/2009 63 Female 128 lb 5/21/2011 Physician Japan
Primary
Concomitant
Haematemesis Other Serious 5/3/2010 57 Male 179 lb 6/2/2011 Physician Japan
Primary
Concomitant
Hypothyroidism Hospitalization 7/29/2009 67 Female 99 lb 6/3/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Hospitalization 7/4/2010 86 Female 104 lb 6/3/2011 Physician Japan
Primary
Concomitant
Face Oedema Other Serious 8/5/2010 69 Male 152 lb 6/3/2011 Physician Japan
Primary
Concomitant
Pain Death 5/26/2008 33 Female 143 lb 6/3/2011 Physician Japan
Primary
Secondary
Concomitant
Rash Generalised Death 5/3/2010 57 Male 179 lb 6/6/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 5/16/2011 77 Female 137 lb 6/8/2011 Physician Japan
Primary
Concomitant
Oedema Peripheral Other Serious 8/5/2010 69 Male 152 lb 6/17/2011 Physician Japan
Primary
Concomitant
Aortic Dissection Death 10/7/2008 84 Male 117 lb 6/25/2011 Physician Japan
Primary
Concomitant
General Physical Health Deterioration Hospitalization 9/29/2010 74 Male 7/6/2011 Physician Japan
Primary
Concomitant
Respiratory Failure Death 7/20/2010 68 Male 139 lb 7/19/2011 Physician Japan
Primary
Concomitant
Rash Other Serious 8/5/2010 69 Male 152 lb 8/2/2011 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 8/28/2009 65 Male 128 lb 8/8/2011 Physician Japan
Primary
Concomitant

Drug Data