Nexavar combined with Oxycontin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sinus Cancer Metastatic Death 3/28/2006 36 Female 4/13/2006 United States
Primary
Concomitant
Therapy Non-responder Death 4/13/2006 Male 164 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Thrombophlebitis Hospitalization 3/7/2006 61 Male 5/10/2006 Physician United States
Primary
Concomitant
Yellow Skin Hospitalization 3/7/2006 61 Male 5/25/2006 Physician United States
Primary
Concomitant
Rash Disability 2/13/2006 61 Female 4/24/2006 United States
Primary
Concomitant
Neuropathy Peripheral Disability 2/10/2006 56 Male 270 lb 4/24/2006 United States
Primary
Concomitant
Rash Pruritic 2/15/2005 65 Female 4/24/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred 2/1/2006 69 Female 4/24/2006 United States
Primary
Concomitant
Hypercalcaemia Hospitalization 5/16/2006 55 Male 201 lb 7/5/2006 France
Primary
Concomitant
Yellow Skin Hospitalization 3/7/2006 61 Male 7/10/2006 Physician United States
Primary
Concomitant
Yellow Skin Hospitalization 3/7/2006 61 Male 7/18/2006 United States
Primary
Concomitant
Femur Fracture Hospitalization 10/1/2005 78 Male 7/26/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 5/16/2006 55 Male 201 lb 7/27/2006 France
Primary
Concomitant
Vision Blurred 2/1/2006 70 Female 7/12/2006 United States
Primary
Concomitant
Skin Burning Sensation 5/23/2006 36 Female 180 lb 7/12/2006 United States
Primary
Concomitant
Sinus Congestion Hospitalization 5/1/2006 27 Male 7/12/2006 United States
Primary
Secondary
Concomitant
Urticaria Disability 2/13/2006 61 Female 7/12/2006 United States
Primary
Concomitant
Neuropathy Peripheral Disability 2/10/2006 56 Male 270 lb 7/12/2006 United States
Primary
Concomitant
Rash Macular 3/1/2006 73 Male 7/12/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 59 Male 134 lb 10/2/2006 Physician United States
Primary
Concomitant
Femur Fracture Hospitalization 10/1/2005 78 Male 10/4/2006 Other Health Professional United States
Primary
Concomitant
Rash Maculo-papular 7/15/2006 61 Male 10/23/2006 United States
Primary
Concomitant
Vision Blurred 2/1/2006 70 Female 155 lb 10/23/2006 United States
Primary
Concomitant
Rash Macular 3/1/2006 73 Male 10/23/2006 United States
Primary
Concomitant
Urticaria Disability 2/13/2006 61 Female 10/23/2006 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 5/16/2006 55 Male 201 lb 2/1/2007 France
Primary
Concomitant
Mental Status Changes Other Serious 1/11/2007 46 Male 3/5/2007 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 5/1/2006 54 Male 5/11/2007 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 5/6/2006 54 Male 8/24/2007 Physician United States
Primary
Concomitant
Death Death 7/10/2007 53 Male 8/24/2007 Physician United States
Primary
Concomitant
Neurological Examination Abnormal Disability 3/15/2007 57 Male 10/19/2007 Physician Italy
Primary
Concomitant
Hepatic Neoplasm Malignant Death 30 Male 146 lb 12/17/2007 Physician Australia
Primary
Concomitant
Haemorrhage Hospitalization 2/1/2008 71 Male 4/3/2008 Netherlands
Primary
Concomitant
Pulmonary Haemorrhage Hospitalization 2/1/2008 71 Male 4/7/2008 Netherlands
Primary
Concomitant
Dehydration Hospitalization 4/14/2008 61 Male 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/14/2008 61 Male 5/2/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/9/2008 49 Male 6/4/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting 5/1/2008 47 Male 6/9/2008 Consumer United States
Primary
Concomitant
Haemolytic Anaemia Hospitalization 5/23/2008 53 Male 6/10/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/9/2008 49 Male 6/11/2008 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 4/22/2008 72 Male 132 lb 6/16/2008 Physician Japan
Primary
Concomitant
Hypoaesthesia Hospitalization 1/18/2008 52 6/18/2008 Physician France
Primary
Concomitant
Stomatitis Other Serious 4/22/2008 72 Male 132 lb 6/26/2008 Physician Japan
Primary
Concomitant
Haemoptysis Hospitalization 5/23/2008 53 Male 7/2/2008 United States
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 6/13/2008 66 Male 157 lb 7/8/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 6/6/2008 73 Male 141 lb 7/9/2008 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Stage Iv Death 6/30/2008 73 Male 134 lb 8/11/2008 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 7/4/2008 59 Male 8/13/2008 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/16/2008 60 Male 161 lb 8/21/2008 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 7/10/2008 64 Male 8/25/2008 Physician Japan
Primary
Concomitant
Peritonitis Hospitalization 7/10/2008 64 Male 9/8/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 6/6/2008 73 Male 141 lb 9/9/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/28/2008 53 Female 112 lb 9/10/2008 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 5/15/2008 41 Male 150 lb 9/10/2008 Physician Japan
Primary
Concomitant
Sepsis Other Serious 7/29/2008 71 Male 95 lb 9/11/2008 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/9/2008 52 Male 143 lb 9/30/2008 Physician Japan
Primary
Concomitant
Jaundice Hospitalization 5/31/2008 67 Male 115 lb 10/2/2008 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/16/2008 60 Male 161 lb 10/3/2008 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/11/2008 Female 10/7/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 6/5/2008 73 Male 141 lb 10/10/2008 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 5/15/2008 41 Male 150 lb 10/10/2008 Physician Japan
Primary
Concomitant
Sepsis Death 3/31/2008 72 Male 141 lb 10/30/2008 Physician Japan
Primary
Concomitant
Oropharyngeal Blistering 1/1/2008 54 Male 11/3/2008 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 5/9/2008 52 Male 143 lb 11/14/2008 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 9/8/2008 53 Female 97 lb 11/17/2008 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 9/2/2008 58 Male 132 lb 11/21/2008 Physician Japan
Primary
Concomitant
Hypernatraemia Hospitalization 50 Male 11/21/2008 Physician Australia
Primary
Concomitant
Rash Death 10/5/2008 69 Male 154 lb 12/1/2008 Physician Japan
Primary
Concomitant
Sudden Death Death 11/16/2008 70 Male 121 lb 12/1/2008 Physician Japan
Primary
Concomitant
Sudden Death Death 10/20/2008 75 Male 12/1/2008 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 10/31/2008 57 Male 141 lb 12/4/2008 Physician Japan
Primary
Concomitant
Tumour Haemorrhage Life Threatening 10/31/2008 57 Male 141 lb 12/11/2008 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 7/4/2008 59 Male 12/12/2008 Physician Japan
Primary
Secondary
Tumour Haemorrhage Life Threatening 10/31/2008 57 Male 141 lb 12/12/2008 Physician Japan
Primary
Concomitant
Large Intestinal Ulcer Hospitalization 11/21/2008 74 Male 123 lb 12/17/2008 Physician Japan
Primary
Concomitant
Tumour Haemorrhage Life Threatening 10/31/2008 57 Male 141 lb 12/22/2008 Physician Japan
Primary
Concomitant
Jaundice Hospitalization 5/31/2008 67 Male 115 lb 12/26/2008 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 6/13/2008 62 Male 139 lb 12/29/2008 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 9/11/2008 61 Female 115 lb 12/29/2008 Physician Japan
Primary
Concomitant
Rash Other Serious 3/28/2008 72 Male 141 lb 12/29/2008 Physician Japan
Primary
Concomitant
Oropharyngeal Blistering 1/1/2008 54 Male 10/3/2008 Pharmacist United States
Primary
Concomitant
Tumour Haemorrhage Life Threatening 10/31/2008 57 Male 141 lb 1/6/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 4/28/2008 54 Male 161 lb 1/13/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/8/2008 61 Male 139 lb 1/19/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 4/28/2008 54 Male 161 lb 1/22/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/13/2009 73 Male 99 lb 2/3/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 10/30/2008 59 Male 150 lb 2/3/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/13/2009 73 Male 99 lb 2/11/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 4/28/2008 54 Male 161 lb 2/16/2009 Physician Japan
Primary
Concomitant
Renal Necrosis Hospitalization 1/6/2009 59 Male 2/16/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 4/28/2008 54 Male 161 lb 2/17/2009 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 7/29/2008 71 Male 95 lb 2/19/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 12/18/2008 42 Female 95 lb 2/20/2009 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Stage Iv Life Threatening 7/4/2008 59 Male 2/23/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 9/19/2008 70 Male 143 lb 2/23/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 11/17/2008 75 Male 152 lb 3/18/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 7/26/2008 67 Male 150 lb 3/30/2009 Physician Japan
Primary
Concomitant
Performance Status Decreased Other Serious 1/31/2009 91 Male 154 lb 3/31/2009 United States
Primary
Concomitant
Tumour Excision Hospitalization 7/22/2008 66 Male 126 lb 4/2/2009 Physician Japan
Primary
Concomitant
Hyperkalaemia Hospitalization 3/5/2009 69 Male 121 lb 4/14/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/28/2008 53 Female 112 lb 4/15/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/13/2009 73 Male 99 lb 4/16/2009 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 6/13/2008 62 Male 139 lb 4/20/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 1/11/2009 54 Female 4/24/2009 Netherlands
Primary
Concomitant
Malaise Hospitalization 7/22/2008 71 Male 139 lb 4/28/2009 Physician Japan
Primary
Concomitant
Atrioventricular Block Complete Hospitalization 4/19/2009 72 Female 5/11/2009 Physician Norway
Primary
Concomitant
Renal Cell Carcinoma Other Serious 4/1/2009 70 Male 5/19/2009 Physician Ireland
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 9/8/2008 53 Female 97 lb 5/19/2009 Physician Japan
Primary
Concomitant
Tumour Excision Hospitalization 7/22/2008 66 Male 126 lb 5/21/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 1/11/2009 54 Female 5/28/2009 Netherlands
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 11/17/2008 75 Male 152 lb 6/1/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 5/23/2009 81 Male 157 lb 6/1/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 4/1/2009 70 Male 6/3/2009 Physician Ireland
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 3/5/2009 69 Male 121 lb 6/9/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 7/22/2008 71 Male 139 lb 6/24/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/16/2008 60 Male 161 lb 6/30/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/28/2008 53 Female 112 lb 7/2/2009 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 6/13/2008 62 Male 139 lb 7/8/2009 Physician Japan
Primary
Concomitant
Respiratory Arrest Hospitalization 7/22/2008 71 Male 139 lb 7/8/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/28/2008 53 Female 112 lb 7/8/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 4/28/2008 54 Male 161 lb 7/10/2009 Physician Japan
Primary
Concomitant
Vomiting Death 6/5/2009 75 Female 101 lb 7/20/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Other Serious 5/12/2008 79 Male 126 lb 7/22/2009 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 7/5/2009 61 Male 7/27/2009 Physician Japan
Primary
Concomitant
Sudden Death Death 11/16/2008 70 Male 121 lb 7/28/2009 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 5/12/2008 79 Male 126 lb 7/28/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 62 Male 121 lb 7/30/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/25/2008 59 Male 134 lb 8/3/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/3/2009 64 Male 128 lb 8/4/2009 Physician Japan
Primary
Concomitant
Vomiting Death 6/5/2009 75 Female 101 lb 8/5/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Other Serious 5/12/2008 79 Male 126 lb 8/6/2009 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 3/5/2009 69 Male 95 lb 8/6/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/15/2008 72 Male 146 lb 8/13/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 62 Male 121 lb 8/14/2009 Physician Japan
Primary
Concomitant
Vomiting Death 6/5/2009 75 Female 101 lb 8/17/2009 Physician Japan
Primary
Secondary
Concomitant
Metabolic Encephalopathy Hospitalization 6/8/2009 67 Male 112 lb 8/20/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/8/2009 55 Female 112 lb 8/21/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 6/2/2009 46 Male 157 lb 8/24/2009 Physician Japan
Primary
Concomitant
Malaise Hospitalization 7/2/2009 80 Male 117 lb 8/27/2009 Physician Japan
Primary
Concomitant
Tumour Haemorrhage Other Serious 7/5/2009 52 Male 143 lb 8/28/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/25/2008 59 Male 134 lb 8/31/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/25/2008 59 Male 134 lb 8/31/2009 Physician Japan
Primary
Concomitant
Liver Disorder Life Threatening 7/6/2009 48 Male 170 lb 9/8/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/9/2009 62 Male 159 lb 9/10/2009 Physician Japan
Primary
Secondary
Varicose Vein Ruptured Life Threatening 6/24/2009 36 Male 117 lb 9/10/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 6/24/2009 58 Male 225 lb 9/16/2009 Other Health Professional United States
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 6/8/2009 67 Male 112 lb 9/18/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 6/24/2009 58 Male 225 lb 9/24/2009 Other Health Professional United States
Primary
Concomitant
Varicose Vein Ruptured Life Threatening 6/24/2009 36 Male 117 lb 9/24/2009 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 6/13/2008 62 Male 139 lb 10/7/2009 Physician Japan
Primary
Concomitant

Drug Data