Navelbine combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Debridement Other Serious 4/1/2005 48 Female 117 lb 1/10/2006 Physician France
Primary
Secondary
Concomitant
Off Label Use Death 5/11/2005 62 Female 1/12/2006 Consumer United States
Primary
Concomitant
Pain In Jaw Other Serious 12/1/2005 59 Female 1/19/2006 United States
Primary
Concomitant
Toothache Other Serious 8/26/2005 56 Female 1/24/2006 Physician Belgium
Primary
Secondary
Concomitant
Pain In Jaw Death 5/1/2005 56 Female 2/2/2006 United States
Primary
Concomitant
Osteonecrosis Disability 11/10/2005 51 Female 176 lb 2/17/2006 Consumer France
Primary
Secondary
Concomitant
Tooth Extraction Disability 9/8/2005 51 Female 176 lb 2/18/2006 France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 8/1/2004 62 Female 2/24/2006 Physician Brazil
Primary
Concomitant
Vomiting Other Serious 6/27/2001 Female 2/24/2006 Lawyer United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 72 Female 3/1/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Other Serious 9/8/2004 63 Male 4/4/2006 United States
Primary
Concomitant
Pain In Jaw Disability 2/7/2006 64 Female 4/30/2006 Italy
Primary
Concomitant
Tooth Extraction Other Serious 4/18/2003 42 Female 111 lb 5/5/2006 Lawyer United States
Primary
Concomitant
Tooth Extraction Hospitalization 4/1/2005 25 Female 132 lb 5/5/2006 France
Primary
Secondary
Concomitant
Wound Treatment Other Serious 10/1/2005 69 Female 5/9/2006 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 10/1/2005 69 Female 5/9/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/30/2005 80 Female 6/5/2006 United States
Primary
Concomitant
Pain Other Serious 6/1/2005 91 Male 6/14/2006 Other Health Professional United States
Primary
Concomitant
Wound Debridement Other Serious 5/1/2005 63 Female 108 lb 6/21/2006 Physician France
Primary
Concomitant
Tooth Loss Other Serious 10/29/2004 39 Female 7/6/2006 Physician United States
Primary
Concomitant
Wound Debridement Other Serious 8/12/2005 51 Female 7/11/2006 Physician France
Primary
Concomitant
Wound Debridement Other Serious 6/1/2004 62 Female 117 lb 7/18/2006 Physician Germany
Primary
Concomitant
Stomatitis Other Serious 5/1/2006 64 Female 7/24/2006 Other Health Professional United States
Primary
Concomitant
Wound Debridement Other Serious 2/22/2005 67 Female 7/26/2006 Physician Germany
Primary
Concomitant
Tooth Extraction Other Serious 9/1/2004 76 Male 8/4/2006 Other Health Professional United States
Primary
Concomitant
Trismus Other Serious 3/1/2000 53 Female 8/4/2006 United States
Primary
Secondary
Concomitant
Trismus Other Serious 3/1/2000 53 Female 8/4/2006 United States
Primary
Secondary
Concomitant
Renal Vasculitis Hospitalization 6/10/2006 58 Female 183 lb 8/9/2006 Other Health Professional France
Primary
Secondary
Tooth Loss Other Serious 1/1/2006 65 Female 8/15/2006 Physician Japan
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 8/19/2006 France
Primary
Secondary
Surgery Hospitalization 9/1/2005 Female 117 lb 8/25/2006 Physician France
Primary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 8/19/2006 France
Primary
Secondary
Stomatitis Other Serious 5/1/2006 64 Female 8/30/2006 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 57 6/6/2006 Other Health Professional United States
Primary
Concomitant
Tooth Loss Other Serious 1/1/2006 65 Female 9/12/2006 Physician Japan
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 8/8/2006 France
Primary
Secondary
Concomitant
Toothache Other Serious 8/26/2005 56 Female 9/26/2006 Physician Belgium
Primary
Secondary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2006 65 Female 10/4/2006 Physician Japan
Primary
Secondary
Concomitant
Wound Debridement Other Serious 3/17/2005 64 Female 10/18/2006 United States
Primary
Concomitant
Tooth Loss Other Serious 1/1/2006 65 Female 10/25/2006 Physician Japan
Primary
Secondary
Concomitant
Tooth Abscess Death 5/9/2006 43 Female 148 lb 11/6/2006 Physician Germany
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 11/8/2006 Other Health Professional France
Primary
Secondary
Swelling Disability 1/1/2005 61 Female 11/9/2006 Switzerland
Primary
Concomitant
Pyrexia Death 5/9/2006 43 Female 148 lb 11/10/2006 Physician Germany
Primary
Secondary
Concomitant
Sequestrectomy Other Serious 4/23/2006 52 Female 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Periodontitis Disability 1/1/2004 50 Female 11/15/2006 Switzerland
Primary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 11/17/2006 France
Primary
Secondary
Restlessness Death 5/9/2006 43 Female 148 lb 11/10/2006 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/13/2006 56 Female 190 lb 11/18/2006 Other Health Professional Brazil
Primary
Concomitant
Wound Debridement Other Serious 11/1/2005 67 Female 134 lb 11/18/2006 Physician Brazil
Primary
Concomitant
Vomiting Other Serious 6/27/2001 66 Female 159 lb 11/20/2006 Lawyer United States
Primary
Secondary
Concomitant
Tooth Infection Other Serious 3/1/2006 66 Female 174 lb 12/5/2006 Physician France
Primary
Concomitant
Osteonecrosis Disability 6/1/2006 57 Female 12/20/2006 Physician Belgium
Primary
Secondary
Concomitant
Wound Debridement Other Serious 3/17/2005 64 Female 12/21/2006 Physician United States
Primary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Sequestrectomy Other Serious 4/23/2006 53 Female 12/29/2006 Japan
Primary
Secondary
Concomitant
Trismus Other Serious 3/1/2000 53 Female 1/8/2007 United States
Primary
Secondary
Concomitant
Sequestrectomy Other Serious 4/23/2006 53 Female 1/18/2007 Japan
Primary
Secondary
Concomitant
Tremor Other Serious 7/1/2006 59 Female 1/19/2007 Physician Japan
Primary
Secondary
Toothache Other Serious 7/12/2005 37 Female 1/24/2007 Physician United States
Primary
Concomitant
Tooth Extraction Disability 2/1/2005 37 Female 1/27/2007 France
Primary
Concomitant
Tumour Ulceration Other Serious 4/23/2006 53 Female 132 lb 1/29/2007 Japan
Primary
Secondary
Concomitant
Wound Debridement Other Serious 7/9/2002 59 Female 1/30/2007 United States
Primary
Secondary
Concomitant
Renal Vasculitis Hospitalization 6/10/2006 58 Female 183 lb 2/2/2007 Other Health Professional France
Primary
Secondary
Tooth Extraction Other Serious 6/1/2005 77 Female 2/2/2007 France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2004 73 Male 2/2/2007 Switzerland
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 70 Female 2/2/2007 Switzerland
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 70 Female 2/2/2007 Switzerland
Primary
Secondary
Concomitant
Vomiting Other Serious 6/27/2001 66 Female 159 lb 2/6/2007 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/27/2001 66 Female 159 lb 2/14/2007 Lawyer United States
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 2/15/2007 France
Primary
Secondary
Vomiting Other Serious 4/18/2003 42 Female 111 lb 2/16/2007 Lawyer United States
Primary
Concomitant
Wound Drainage Other Serious 4/13/2000 47 Female 179 lb 2/21/2007 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 1/22/2007 Female 2/22/2007 Physician Belgium
Primary
Concomitant
Tremor Other Serious 7/1/2006 59 Female 3/7/2007 Physician Japan
Primary
Secondary
Tooth Extraction Other Serious 1/1/2006 Female 3/7/2007 Physician Belgium
Primary
Concomitant
Pain Other Serious 1/22/2007 Female 3/14/2007 Physician Belgium
Primary
Concomitant
Wound Treatment Other Serious 1/1/1998 57 Female 150 lb 3/17/2007 Lawyer United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/13/2000 47 Female 207 lb 3/20/2007 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2005 69 Female 3/27/2007 United States
Primary
Secondary
Concomitant
Renal Vasculitis Hospitalization 6/10/2006 58 Female 3/2/2007 France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/23/2006 73 Female 119 lb 3/31/2007 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 4/13/2000 47 Female 207 lb 4/5/2007 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/2006 59 124 lb 4/5/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2007 53 Female 4/11/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2005 Female 127 lb 4/11/2007 United States
Primary
Concomitant
Tooth Abscess Other Serious 2/1/2007 Female 4/13/2007 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Other Serious 2/1/2007 64 Female 150 lb 4/17/2007 Physician Germany
Primary
Concomitant
X-ray Abnormal Other Serious 9/1/2006 59 Female 124 lb 4/18/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2007 53 Female 5/8/2007 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/23/2006 53 Female 132 lb 5/22/2007 Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/8/2007 42 Female 121 lb 5/30/2007 Physician France
Primary
Concomitant
Vomiting Other Serious 4/18/2003 5/30/2007 Lawyer United States
Primary
Concomitant
Tooth Extraction Other Serious 12/11/2006 53 Female 6/8/2007 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 4/13/2000 47 Female 207 lb 6/8/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/11/2006 53 Female 6/8/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 6/27/2001 6/12/2007 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/14/2007 Female 6/19/2007 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/23/2006 53 Female 132 lb 6/22/2007 Japan
Primary
Secondary
Concomitant
Weight Decreased Disability 11/1/2006 Female 150 lb 6/22/2007 Physician France
Primary
Concomitant
Toothache Disability 1/1/2003 66 Female 6/28/2007 France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 6/29/2007 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Disability 6/23/2006 66 110 lb 7/2/2007 Other Health Professional France
Primary
Secondary
Concomitant
Wound Drainage Other Serious 11/23/2001 52 Female 178 lb 7/12/2007 Lawyer United States
Primary
Concomitant
Osteonecrosis Disability 6/23/2006 66 110 lb 7/12/2007 Other Health Professional France
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2001 Female 167 lb 7/19/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2001 Female 167 lb 7/19/2007 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/7/2005 68 Female 8/10/2007 United States
Primary
Concomitant
Tooth Extraction Other Serious 9/7/2005 68 Female 8/10/2007 United States
Primary
Concomitant
Renal Failure Acute Death 7/10/2007 52 Female 8/17/2007 Physician Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Wound Dehiscence Other Serious 2/22/2005 67 Female 8/31/2007 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 12/1/2005 75 Female 9/6/2007 France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/15/2007 75 Female 9/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Death 7/10/2007 52 Female 9/7/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/19/2007 64 Female 9/8/2007 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/12/2000 60 Female 9/19/2007 France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/19/2007 64 Female 9/21/2007 Physician Japan
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 1/1/2004 53 Female 9/29/2007 France
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/12/2000 60 Female 10/6/2007 France
Primary
Secondary
Concomitant
Toothache Hospitalization 2/1/2006 61 Female 95 lb 10/6/2007 Japan
Primary
Secondary
Concomitant
Toothache Hospitalization 2/1/2006 61 Female 95 lb 10/16/2007 Japan
Primary
Secondary
Concomitant
Toothache Hospitalization 2/1/2006 61 Female 95 lb 10/26/2007 Japan
Primary
Secondary
Concomitant
Renal Failure Acute Death 7/10/2007 52 Female 10/29/2007 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/1/2003 46 Female 166 lb 10/29/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 6/1/2007 54 Female 11/23/2007 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 6/1/2007 54 Female 11/23/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/14/2007 63 Female 12/12/2007 Physician United States
Primary
Secondary
Sequestrectomy Other Serious 2/1/2007 Female 12/19/2007 Physician Germany
Primary
Concomitant
Wound Drainage Other Serious 11/23/2001 52 Female 178 lb 1/7/2008 Lawyer United States
Primary
Secondary
Concomitant
Ulcer Other Serious 10/1/2007 Male 154 lb 1/17/2008 Physician France
Primary
Secondary
Osteonecrosis Disability 52 Female 1/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 4/20/2006 52 Female 1/22/2008 France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/18/2008 1/31/2008 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 1/18/2008 47 Female 106 lb 2/11/2008 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 12/14/2007 Female 2/13/2008 Physician United States
Primary
Concomitant
Osteonecrosis Disability 4/20/2006 Female 2/14/2008 Physician United Kingdom
Primary
Secondary
Tumour Marker Increased Other Serious 1/1/2000 67 Female 167 lb 2/14/2008 United States
Primary
Secondary
Concomitant
Breast Cancer Metastatic Death 7/1/2007 Female 2/15/2008 Physician United States
Primary
Concomitant
Osteonecrosis Disability 4/20/2006 Female 2/20/2008 Physician United Kingdom
Primary
Secondary
Tooth Extraction Other Serious 1/1/2003 46 Female 170 lb 2/29/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2000 67 Female 167 lb 3/3/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/18/2008 47 Female 106 lb 3/10/2008 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/5/2007 62 Female 3/8/2008 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/23/2004 3/18/2008 United States
Primary
Concomitant
Wound Drainage Other Serious 4/13/2000 47 Female 207 lb 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/23/2006 Female 3/25/2008 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/5/2007 62 Female 3/27/2008 Physician Japan
Primary
Secondary
Concomitant

Drug Data