Nadolol combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Therapeutic Agent Toxicity Hospitalization 42 Female 1/27/2006 Spain
Primary
Concomitant
Memory Impairment Other Serious Male 202 lb 2/1/2006 United States
Primary
Secondary
Concomitant
Portal Vein Thrombosis Other Serious 1/9/2006 67 Male 148 lb 3/13/2006 Physician Spain
Primary
Concomitant
Muscle Spasms Other Serious 10/1/2004 41 Male 4/12/2006 Physician United States
Primary
Concomitant
Postoperative Infection Hospitalization 7/22/2006 38 Male 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/22/2006 38 Male 210 lb 8/14/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/22/2006 38 Male 210 lb 8/25/2006 Consumer United States
Primary
Secondary
Concomitant
Back Pain 6/13/2006 35 Female 9/27/2006 Other Health Professional United States
Primary
Concomitant
Renal Haemorrhage Other Serious 1/1/1999 49 Female 175 lb 10/16/2006 Lawyer United States
Primary
Concomitant
Encephalopathy Hospitalization 87 Male 10/23/2006 Physician United States
Primary
Concomitant
Fatigue Hospitalization 11/15/2006 Male 12/6/2006 Consumer Canada
Primary
Concomitant
Liver Disorder Other Serious 11/15/2006 Male 12/21/2006 Consumer Canada
Primary
Concomitant
Renal Failure Acute Other Serious 10/4/2004 57 Male 2/5/2007 Pharmacist United States
Primary
Secondary
Disease Progression Death 2/5/2007 63 Male 223 lb 2/9/2007 Consumer United States
Primary
Secondary
Concomitant
Dry Mouth 1/1/2006 55 Male 12/5/2006 United States
Primary
Concomitant
Vision Blurred Required Intervention 12/18/2006 66 Male 12/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/21/2007 52 Female 6/4/2007 United States
Primary
Concomitant
Upper Respiratory Tract Infection 2/1/2007 74 Female 5/17/2007 United States
Primary
Concomitant
Metastases To Central Nervous System Death 3/5/2007 51 Female 7/10/2007 United States
Primary
Concomitant
Metastases To Central Nervous System Death 3/5/2007 51 Female 7/31/2007 United States
Primary
Concomitant
Vomiting Hospitalization 7/25/2007 61 Female 159 lb 9/27/2007 Pharmacist United States
Primary
Concomitant
Inguinal Hernia, Obstructive Hospitalization 12/3/2007 Female 1/7/2008 Physician Canada
Primary
Concomitant
Blood Pressure Increased Other Serious 1/8/2008 Male 160 lb 2/8/2008 United States
Primary
Concomitant
Paraesthesia 9/27/2007 53 Female 145 lb 1/10/2008 Consumer United States
Primary
Concomitant
Rash Pruritic Life Threatening 3/17/2008 Female 123 lb 3/21/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 Male 160 lb 3/21/2008 United States
Primary
Secondary
Concomitant
Rash Pruritic Life Threatening 3/17/2008 Female 123 lb 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Hypotension Required Intervention 2/22/2008 50 Male 163 lb 3/12/2008 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased Other Serious 6/22/2008 Female 172 lb 7/2/2008 Consumer United States
Primary
Concomitant
Transfusion Reaction Other Serious 5/1/2007 Female 7/7/2008 Consumer United States
Primary
Concomitant
Dyspnoea 6/18/2008 Female 7/24/2008 Consumer United States
Primary
Concomitant
Feeling Abnormal Other Serious 1/1/2008 Female 168 lb 7/25/2008 Consumer United States
Primary
Concomitant
Blood Pressure Increased 5/5/2008 56 Female 7/7/2008 Consumer United States
Primary
Concomitant
Dyspnoea 6/18/2008 Female 8/13/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2006 Male 321 lb 8/19/2008 Physician United States
Primary
Concomitant
Dyspnoea 6/18/2008 Female 185 lb 8/29/2008 Physician United States
Primary
Concomitant
Dyspnoea 6/18/2008 Female 185 lb 9/11/2008 Physician
Primary
Concomitant
Pain In Extremity Hospitalization 6/1/2008 42 Female 144 lb 9/4/2008 United States
Primary
Concomitant
Varices Oesophageal Other Serious 5/1/2007 Female 9/18/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2006 Male 321 lb 10/2/2008 Physician United States
Primary
Concomitant
Drug Screen Positive Other Serious 9/10/2008 Male 180 lb 10/9/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 64 Male 179 lb 11/6/2008 Consumer Canada
Primary
Concomitant
Oesophageal Varices Haemorrhage Other Serious 6/15/2008 Female 11/5/2008 Consumer United States
Primary
Concomitant
Retroperitoneal Fibrosis Hospitalization 33 Female 1/7/2009
Primary
Secondary
Retroperitoneal Fibrosis Hospitalization 33 Female 1/28/2009 Physician New Zealand
Primary
Secondary
Concomitant
Oedema 5/1/2008 Female 99 lb 2/5/2009 Physician United States
Primary
Concomitant
Pruritus Generalised Other Serious 1/1/2009 Female 110 lb 2/17/2009 Consumer United States
Primary
Concomitant
Infection Hospitalization 3/27/2009 Female 159 lb 3/30/2009 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 3/27/2009 Male 4/14/2009 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 3/27/2009 Male 4/24/2009 Physician United States
Primary
Concomitant
Portal Hypertension Other Serious Male 5/1/2009 Consumer United States
Primary
Concomitant
Presyncope Hospitalization Male 5/1/2009 Physician United States
Primary
Concomitant
Hyponatraemia Hospitalization 8/27/2008 Male 5/1/2009 Physician United States
Primary
Concomitant
Nausea Male 5/4/2009 Physician United States
Primary
Concomitant
Wheezing Hospitalization 4/8/2009 176 lb 5/15/2009 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/10/2009 79 Female 5/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 9/24/2007 65 Male 262 lb 6/18/2009 United States
Primary
Concomitant
Dizziness 2/1/2009 Male 6/12/2009 Pharmacist United States
Primary
Concomitant
Hepatic Failure Other Serious 9/24/2007 65 Male 262 lb 6/24/2009 United States
Primary
Concomitant
Wheezing Hospitalization 4/8/2009 176 lb 6/25/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 1/1/2008 Female 233 lb 6/29/2009 Consumer United States
Primary
Concomitant
Off Label Use Other Serious 55 Female 7/2/2009 Physician United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 1/1/2008 Female 238 lb 7/17/2009 Physician United States
Primary
Concomitant
Anaemia 1/1/2008 Female 7/23/2009 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 1/1/2008 Female 238 lb 8/19/2009 Physician United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 1/1/2008 Female 238 lb 9/11/2009 Physician United States
Primary
Concomitant
Weight Increased Life Threatening 7/5/2009 Male 254 lb 9/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tibia Fracture Required Intervention 7/12/2009 61 Male 195 lb 7/13/2009 United States
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 76 Female 10/19/2009 Pharmacist United States
Primary
Concomitant
Somnolence 3/1/2009 Male 175 lb 11/5/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 1/25/2008 56 Male 11/20/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 1/25/2008 56 Male 12/1/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 1/25/2008 56 Male 12/11/2009 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 12/1/2009 Male 292 lb 2/5/2010 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 12/1/2009 Male 292 lb 2/22/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 12/15/2009 62 Male 196 lb 5/17/2010 Consumer United States
Primary
Secondary
Concomitant
Incoherent Hospitalization 4/21/2010 73 Male 198 lb 5/15/2010 United States
Primary
Concomitant
Death Hospitalization 7/3/2010 53 Male 200 lb 7/21/2010 Consumer United States
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 7/3/2010 53 Male 200 lb 7/30/2010 Consumer United States
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 7/3/2010 53 Male 200 lb 8/3/2010 Consumer United States
Primary
Concomitant
Malignant Ascites Hospitalization 8/9/2010 70 Male 8/23/2010 Physician Australia
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious Female 9/2/2010 Pharmacist United States
Primary
Concomitant
Malignant Ascites Hospitalization 8/9/2010 70 Male 9/10/2010 Physician Australia
Primary
Secondary
Concomitant
Malignant Ascites Hospitalization 8/9/2010 70 Male 9/13/2010 Physician Australia
Primary
Secondary
Concomitant
Restlessness Required Intervention 53 Female 9/21/2010 Other Health Professional United States
Primary
Concomitant
Withdrawal Syndrome Hospitalization 53 Female 9/28/2010 Pharmacist United States
Primary
Concomitant
Peritonitis Bacterial Other Serious 8/9/2010 70 Male 11/10/2010 Physician Australia
Primary
Secondary
Concomitant
Weight Increased 2/1/2010 54 Female 11/23/2010 Consumer United States
Primary
Concomitant
Headache 12/1/2010 72 Female 1/11/2011 Consumer
Primary
Concomitant
Ammonia Increased Hospitalization 11/9/2010 59 Male 235 lb 1/28/2011 Physician United States
Primary
Concomitant
Anal Cancer Hospitalization 10/6/2010 69 Male 1/28/2011 Physician United States
Primary
Concomitant
Asthenia Other Serious 12/20/2010 60 Female 157 lb 3/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anal Cancer Hospitalization 10/6/2010 69 Male 3/7/2011 Physician United States
Primary
Concomitant
Oesophageal Varices Haemorrhage Death 8/9/2010 69 Male 114 lb 3/9/2011 Physician New Zealand
Primary
Secondary
Concomitant
Bile Duct Cancer Death 70 Male 266 lb 3/17/2011 Other Health Professional United States
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 8/9/2010 69 Male 114 lb 3/19/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 8/9/2010 69 Male 114 lb 3/23/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Hypothermia Death 12/20/2010 60 Female 157 lb 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Reticulocyte Count Increased Hospitalization 3/24/2010 47 Male 322 lb 3/14/2011 Physician United States
Primary
Secondary
Concomitant
Medication Error Other Serious 1/10/2011 39 Male 200 lb 4/6/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 10/1/2003 61 Male 200 lb 4/19/2011 Lawyer United States
Primary
Concomitant
Haematemesis Life Threatening 8/9/2010 69 Male 114 lb 5/27/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Dehydration Hospitalization 8/11/2010 69 Male 115 lb 6/10/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 53 Female 6/20/2011 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/26/2011 61 Female 6/22/2011 Consumer United States
Primary
Concomitant
Fatigue Other Serious 57 Male 7/8/2011 Pharmacist United States
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 1/22/2009 53 Female 7/6/2011 Pharmacist United States
Primary
Secondary
Scrotal Swelling Hospitalization 12/11/2010 63 Male 250 lb 7/12/2011 Physician Canada
Primary
Secondary
Concomitant
Hepatic Encephalopathy Other Serious 12/20/2010 60 Female 157 lb 7/28/2011 Consumer United States
Primary
Secondary
Concomitant
Generalised Oedema Hospitalization 12/20/2010 60 Female 157 lb 7/30/2011 Consumer United States
Primary
Secondary
Concomitant
Infectious Peritonitis Hospitalization 6/7/2011 59 Male 185 lb 7/28/2011 Consumer United States
Primary
Concomitant
Staphylococcal Osteomyelitis Hospitalization 5/15/2011 59 Male 193 lb 8/5/2011 Consumer Canada
Primary
Concomitant
Flushing 1/1/2009 61 Female 230 lb 8/5/2011 Consumer United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization Female 10/11/2011 Consumer United States
Primary
Concomitant
Splenomegaly Hospitalization 3/24/2010 47 Male 322 lb 10/11/2011 Physician United States
Primary
Secondary
Concomitant
Fatigue 66 Female 10/27/2011 Consumer United States
Primary
Concomitant
Chromaturia Other Serious 11/6/2010 59 Male 235 lb 10/31/2011 Other Health Professional United States
Primary
Concomitant
Heart Rate Increased Hospitalization 1/1/2011 67 Female 10/31/2011 Consumer United States
Primary
Concomitant
Fluid Retention Hospitalization 12/11/2010 63 Male 250 lb 11/2/2011 Physician Canada
Primary
Secondary
Concomitant
Fatigue Other Serious 57 Male 11/10/2011 Consumer United States
Primary
Concomitant
Diarrhoea 10/1/2011 66 Female 11/15/2011 Consumer United States
Primary
Concomitant
Movement Disorder Hospitalization 1/1/2011 67 Female 11/25/2011 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Disability 56 Male 280 lb 11/16/2011 Lawyer United States
Primary
Concomitant
Fatigue Other Serious 57 Male 12/2/2011 Pharmacist United States
Primary
Concomitant
Heart Rate Increased Hospitalization 1/1/2011 67 Female 12/19/2011 Physician United States
Primary
Concomitant
Nervousness Hospitalization 12/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lymphadenopathy Life Threatening 54 Female 12/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 4/25/2011 70 Male 249 lb 1/19/2012 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 11/12/2011 77 Female 124 lb 2/24/2012 Consumer United States
Primary
Concomitant
Fatigue Death 10/1/2011 66 Female 3/2/2012 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization Male 3/17/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea 2/22/2012 61 Female 3/14/2012 Pharmacist United States
Primary
Concomitant
Osteoarthritis Hospitalization 2/1/2012 68 Female 251 lb 4/9/2012 Consumer Canada
Primary
Concomitant
Platelet Count Decreased Hospitalization 2/29/2012 59 Male 143 lb 4/10/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Abasia Other Serious 77 Female 120 lb 4/6/2012 Lawyer United States
Primary
Concomitant
Drug Ineffective Other Serious 3/1/2011 54 Female 4/20/2012 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 4/13/2012 55 Female 4/24/2012 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 3/1/2011 54 Female 4/26/2012 Other Health Professional United States
Primary
Concomitant
Diarrhoea Death 10/1/2011 66 Female 5/30/2012 Pharmacist United States
Primary
Concomitant
Peritoneal Tuberculosis Other Serious 8/23/2010 69 Male 114 lb 6/11/2012 Consumer New Zealand
Primary
Secondary
Concomitant
Dehydration Other Serious 4/1/2012 72 Male 6/12/2012 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 5/15/2012 57 Male 240 lb 6/13/2012 Consumer United States
Primary
Concomitant
Insomnia Other Serious 5/11/2012 49 Female 74 lb 6/13/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Haematochezia 3/23/2012 55 Male 288 lb 6/19/2012 Consumer
Primary
Concomitant
Anal Pruritus 3/23/2012 55 Female 145 lb 6/19/2012 Pharmacist United States
Primary
Concomitant
Incorrect Drug Administration Duration 4/13/2012 56 Male 280 lb 6/19/2012 Other Health Professional United States
Primary
Concomitant
Asthenia Other Serious 5/11/2012 49 Female 174 lb 7/13/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 3/13/2012 8/2/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Anaemia Hospitalization 59 Female 97 lb 8/27/2012 Physician Canada
Primary
Concomitant
Ascites Hospitalization 59 Female 97 lb 8/27/2012 Physician Canada
Primary
Secondary
Concomitant

Drug Data