Morphine combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tooth Extraction Other Serious 1/7/2005 58 Female 1/27/2006 Norway
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 11/25/2005 63 Male 2/3/2006
Primary
Secondary
Concomitant
Pain In Jaw Hospitalization 11/25/2005 63 Male 2/3/2006 France
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 11/25/2005 63 Male 2/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 1/23/2006 71 Female 2/17/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 2/24/2006 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 11/25/2005 63 Male 2/21/2006 Physician France
Primary
Secondary
Concomitant
Retching Other Serious 1/10/2006 53 Male 153 lb 2/17/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 12/20/2005 53 Male 153 lb 3/1/2006 United States
Primary
Concomitant
Swelling Other Serious 7/1/2005 86 Female 179 lb 3/28/2006 United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 1/7/2005 58 Female 4/5/2006 Norway
Primary
Secondary
Concomitant
Swelling Other Serious 6/28/2005 86 Female 179 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 6/16/2003 68 Male 4/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 6/16/2003 68 Male 4/23/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Disorder Death 3/25/2006 73 Male 126 lb 4/24/2006 Pharmacist Japan
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 67 Female 5/5/2006 Physician Switzerland
Primary
Concomitant
Treatment Noncompliance Other Serious 49 Female 132 lb 5/4/2006 United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 1/7/2005 58 Female 5/17/2006 Norway
Primary
Secondary
Concomitant
Jaundice Life Threatening 3/23/2006 73 Male 126 lb 5/22/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Hypocalcaemia Other Serious 12/15/2005 79 Female 5/24/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 1/7/2005 58 Female 5/23/2006 Norway
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/23/2006 73 Male 126 lb 6/13/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/6/2006 59 Male 6/16/2006 United States
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/23/2006 71 Female 7/5/2006 Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 67 Female 7/12/2006 Physician Switzerland
Primary
Concomitant
Tooth Extraction Other Serious 4/18/2006 49 Female 121 lb 7/25/2006 Physician Bulgaria
Primary
Secondary
Concomitant
Swelling Other Serious 5/27/2006 59 Male 7/28/2006 United States
Primary
Concomitant
Hypotension Hospitalization 1/28/2006 71 Male 5/24/2006 Other Health Professional United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2004 67 Female 8/4/2006 Physician Switzerland
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 163 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 163 lb 9/12/2006 Other Health Professional United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 9/13/2006 United States
Primary
Secondary
Concomitant
Multiple Myeloma Hospitalization 8/17/2006 63 Male 9/18/2006 Physician United States
Primary
Concomitant
Dysphonia Hospitalization 8/18/2006 62 Female 10/16/2006 Physician Japan
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 9/4/2006 62 Female 150 lb 11/7/2006 United States
Primary
Concomitant
Respiratory Disorder Life Threatening 3/23/2006 73 Male 126 lb 11/8/2006 Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious Male 11/10/2006 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 4/1/2006 68 Female 12/12/2006 United States
Primary
Concomitant
Hepatic Failure Hospitalization 8/25/2006 63 Male 11/28/2006 Physician United States
Primary
Concomitant
Stomatitis Hospitalization 11/5/2006 20 Male 132 lb 12/15/2006 France
Primary
Secondary
Concomitant
Resorption Bone Increased Other Serious 3/8/2006 67 Male 12/20/2006 Pharmacist United States
Primary
Concomitant
Tooth Extraction Disability 9/17/2004 74 Female 104 lb 1/11/2007 France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 4/1/2006 68 Female 1/12/2007 United States
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 1/15/2007 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 5/12/2004 61 Female 139 lb 1/15/2007 France
Primary
Concomitant
Urinary Incontinence Life Threatening 1/31/2007 40 Male 231 lb 2/2/2007 Other Health Professional United States
Primary
Concomitant
Resorption Bone Increased Other Serious 3/8/2006 67 Male 3/15/2007 Pharmacist United States
Primary
Concomitant
Toothache Other Serious 12/1/2005 43 Female 243 lb 3/24/2007 France
Primary
Secondary
Concomitant
Toothache Other Serious Female 4/17/2007 Physician Australia
Primary
Concomitant
Intestinal Perforation Other Serious 1/1/2007 Female 4/27/2007 Other Health Professional Australia
Primary
Concomitant
Toothache Other Serious 4/1/2006 61 Female 5/15/2007 Physician Australia
Primary
Concomitant
Respiratory Disorder Life Threatening 1/31/2007 40 Male 231 lb 6/5/2007 Other Health Professional United States
Primary
Concomitant
Surgery Hospitalization 11/1/2006 65 Male 6/8/2007 Physician Australia
Primary
Secondary
Concomitant
Asthenia Hospitalization 5/5/2005 52 Male 162 lb 5/5/2005 Physician United States
Primary
Secondary
Concomitant
Hepatitis Acute Death 6/14/2007 68 Male 7/3/2007 Physician
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 3/1/2007 56 Male 7/12/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 8/13/2007 Female 8/20/2007 Pharmacist United States
Primary
Concomitant
Waldenstrom's Macroglobulinaemia Hospitalization 8/4/2003 88 Male 165 lb 9/6/2007 Consumer Germany
Primary
Concomitant
Weight Decreased Other Serious 8/1/2007 71 Female 9/14/2007 United States
Primary
Concomitant
Sensory Loss Hospitalization 7/8/2007 64 Male 222 lb 9/13/2007 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 11/25/2003 9/28/2007 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 11/25/2003 10/10/2007 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 11/1/2003 55 Male 261 lb 10/11/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2007 71 Female 10/13/2007 United States
Primary
Concomitant
Surgery Hospitalization 11/1/2006 62 Male 10/19/2007 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2000 71 Female 10/20/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Analysis Increased Other Serious 1/1/2000 71 Female 11/22/2007 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 11/6/2007 Male 240 lb 11/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 11/1/2003 55 Male 261 lb 12/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 12/26/2007 Physician United States
Primary
Secondary
Concomitant
Soft Tissue Disorder Life Threatening 11/28/2007 75 Male 12/19/2007 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 3/1/2007 56 Male 2/13/2008 Other Health Professional United States
Primary
Concomitant
Tooth Infection Other Serious 2/1/2004 54 Female 180 lb 3/3/2008 Physician United States
Primary
Secondary
Concomitant
Insomnia Hospitalization 2/28/2008 46 Female 3/11/2008 Physician United States
Primary
Concomitant
Paranoia Hospitalization 2/28/2008 46 Female 150 lb 3/19/2008 Physician United States
Primary
Concomitant
Paranoia Hospitalization 2/28/2008 46 Female 150 lb 3/19/2008 Physician United States
Primary
Concomitant
Breast Cancer Metastatic Death 56 Female 4/2/2008 United States
Primary
Concomitant
Stomatitis Other Serious 2/20/2007 63 Male 3/31/2008 Physician Japan
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/2/2006 64 Male 4/26/2008 United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2005 Female 210 lb 4/29/2008 United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 1/26/2008 56 Female 218 lb 5/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 6/1/2003 Male 261 lb 5/30/2008 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 5/19/2008 85 Female 5/29/2008 Pharmacist United States
Primary
Concomitant
Toothache Other Serious 10/2/2006 Male 6/3/2008 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1999 Male 182 lb 6/11/2008 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2004 Female 180 lb 6/12/2008 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 4/19/2008 6/12/2008 Physician Japan
Primary
Concomitant
Eschar Hospitalization 4/11/2006 Male 7/8/2008 France
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2006 Male 8/5/2008 Consumer France
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2006 Male 8/8/2008 France
Primary
Concomitant
Vomiting Other Serious 2/1/2004 Female 180 lb 8/12/2008 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1999 Male 182 lb 8/13/2008 United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 Male 130 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2005 Male 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 5/1/2004 Male 297 lb 8/21/2008 United States
Primary
Concomitant
Wound Treatment Other Serious 5/1/2004 Male 297 lb 8/21/2008 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1999 Male 182 lb 8/27/2008 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 4/9/2008 Female 9/3/2008 Other Health Professional France
Primary
Concomitant
Pain Other Serious Male 9/3/2008 United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 1/26/2008 56 Female 218 lb 9/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/9/2008 61 Female 108 lb 9/30/2008 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/9/2008 61 Female 108 lb 9/30/2008 Physician United States
Primary
Secondary
Concomitant
Metastasis Other Serious 8/18/2008 Female 120 lb 10/10/2008 Consumer United States
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 7/2/2008 Female 10/7/2008 Physician France
Primary
Secondary
Concomitant
Tachycardia Hospitalization 11/26/2007 65 Male 161 lb 10/12/2008 Physician Japan
Primary
Secondary
Concomitant
Breast Cancer Metastatic Death 56 Female 9/26/2008 Physician United States
Primary
Concomitant
Toothache Other Serious 10/2/2006 64 Male 9/26/2008 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 3/1/2006 Male 11/7/2008 France
Primary
Concomitant
Osteoarthritis Other Serious 1/17/2008 69 Female 80 lb 11/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/9/2008 61 Female 108 lb 12/4/2008 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2001 Female 147 lb 12/9/2008 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2008 Male 152 lb 12/12/2008 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/26/2007 65 Male 161 lb 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
Tooth Loss Disability 10/1/2008 78 Female 12/29/2008 Other Health Professional Switzerland
Primary
Concomitant
Vomiting Other Serious 1/1/2004 Female 207 lb 1/13/2009 Physician United States
Primary
Concomitant
Tenderness Other Serious 1/1/2004 Female 1/15/2009 Physician United States
Primary
Secondary
Concomitant
Tenderness Required Intervention 1/1/2004 Female 6/24/2008 Physician United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 10/1/2006 Male 1/23/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 12/5/2008 Male 203 lb 1/22/2009 United States
Primary
Secondary
Concomitant
Sepsis Death 1/24/2009 Male 157 lb 2/3/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/21/2004 Female 150 lb 2/3/2009 Physician United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 10/1/2006 Male 2/5/2009 Physician United States
Primary
Concomitant
Toothache Other Serious 1/1/2007 Male 172 lb 2/11/2009 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 4/21/2004 Female 150 lb 2/10/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 2/17/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Death 1/24/2009 Male 157 lb 2/20/2009 Physician United States
Primary
Secondary
Concomitant
Tachycardia Death 1/24/2009 Male 157 lb 2/21/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 1/1/2001 Female 147 lb 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2004 Female 180 lb 3/3/2009 United States
Primary
Secondary
Concomitant
Tachycardia Death 1/24/2009 Male 157 lb 3/5/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/3/2003 Male 3/9/2009 Physician United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 10/1/2006 Male 3/20/2009 Physician United States
Primary
Concomitant
Toothache Other Serious 1/1/2007 Male 172 lb 3/22/2009 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 1/1/2007 Male 172 lb 3/25/2009 Other Health Professional United States
Primary
Concomitant
Swelling Hospitalization 5/1/2008 Female 4/2/2009 Physician Germany
Primary
Concomitant
Interacting
Tooth Extraction Other Serious 4/21/2004 Female 150 lb 4/9/2009 Physician United States
Primary
Secondary
Concomitant
Metastases To Spine Other Serious 5/1/2008 Female 146 lb 4/9/2009 Physician Germany
Primary
Concomitant
Uterine Leiomyoma Other Serious 4/3/2003 Female 4/20/2009 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 4/1/2008 Female 4/21/2009 Physician Japan
Primary
Concomitant
Stem Cell Transplant Other Serious Male 4/22/2009 Other Health Professional United States
Primary
Concomitant
Uterine Leiomyoma Other Serious 4/3/2003 Female 4/29/2009 Physician United States
Primary
Concomitant
Vaginal Infection Other Serious 1/1/2003 Female 218 lb 5/12/2009 Physician United States
Primary
Secondary
Concomitant
Vaginal Infection Other Serious 1/1/2003 Female 218 lb 5/14/2009 Physician United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 3/1/2009 Male 5/19/2009 Physician Japan
Primary
Concomitant
Wheezing Other Serious 2/1/2002 5/20/2009 Lawyer United States
Primary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 Female 5/20/2009 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 1/1/2007 Male 172 lb 5/20/2009 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 10/11/2004 Female 5/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data